iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049707

Ensembl Protein ID

ENSLACP00000011614.1

UniProt Accession

H3APP3; H3APP3_LATCH

Genbank Protein ID

ENSLACP00000011614

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01092229

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010222.1	ENSLACT00000011703.1	ENSLACP00000011614.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.00e-60	206.1	1011	1190

Active Site

Position(s)	Description	Evidence
1159	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 153  eeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggy 239
            + ++pgG+nip t  N++eYv++v+eyrl+e +++qv a+reG+ ++ip  llsl+tee+le l+cG +e++v +lk+  +y++  
   Q: 1011 PVPIIPGGSNIPLTFGNRKEYVERVIEYRLHE-MDQQVRAVREGMASIIPVPLLSLLTEEQLERLVCGVPEVSVAMLKSIVRYRD-A 1095
           3459****************************.**************************************************87.* PP
   S: 240  tedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyA 326
            e+ p i w+w++l+efs+eer  fL+Fv+g+srlP +  + ++ r+ +ir d+  + lP+++TCf++L+LP+Y+s++i+ ++L+y 
   Q: 1096 DESLPLIGWLWQTLQEFSNEERVLFLRFVSGRSRLPDNAADVMQ-RFQIIRVDRPVNGLPTAQTCFFQLRLPPYTSQSIMADRLRYS 1181
           ************************************66655555.99999999999******************************* PP
   S: 327  ieetkgFel 335
           i+++ ++++
   Q: 1182 INNCCSIDM 1190
           ****99886 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MVKIWGRVGT IWLAVQSLYH SALVNTAAWC PLPGVGEDPK LLLAVGCQHG LVYVWAFPQG 60
GAAVPAPGVR NSTQEKAKQK QDRYPSHGSA NCVFRLNGHI TAVKTVSFSP DGLALLSGGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTCATCAG AACAATGCTG ATCTTCTTCC AACAAAGATA AAAATTAATT TCCTTTATTC 60
CAGTGAGGAT TCCTCTCTGC AGACAGACTC ATCTACTGGC ATCGATGTGT CATCAGTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006441	Arabidopsis lyrata	35.24	3.00e-42	167.00
IUUC-Lpe-051165	Leersia perrieri	35.25	7.00e-50	191.00
IUUC-Oba-075262	Oryza barthii	36.16	2.00e-49	189.00
IUUC-Ogl-077586	Oryza glaberrima	36.16	2.00e-49	190.00
IUUC-Ogu-078796	Oryza glumaepatula	35.89	7.00e-49	187.00
IUUC-Oin-079298	Oryza indica	35.89	4.00e-49	188.00
IUUC-Ome-081908	Oryza meridionalis	35.10	2.00e-48	186.00
IUUC-Oni-082049	Oryza nivara	35.89	7.00e-49	187.00
IUUC-Opu-083608	Oryza punctata	35.71	1.00e-49	190.00
IUUC-Oru-084712	Oryza rufipogon	35.89	7.00e-49	187.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence