iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021504

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02007179

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000005822.3	ENSCPOT00000005885.2	ENSCPOP00000005251.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.90e-114	381.9	703	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 703  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 787
           7899********************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di +lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 788  EGIVVDVPFASFFLSQLLGHhhsifYSSVDELPSLDSEFYKNLTSIKRY-DGDIADLGLTLSY--DEDVMGQLVCHELIPGGKTIPV 871
           ********************777777999********************.6788887777766..6999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++a+ +Gf+++i++e++++F++ el+ li+G+ +eid++dlkk+t y gg++ ++++i+w+w+
   Q: 872  TNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSAPELQRLISGDnAEIDLDDLKKHTVYYGGFHGSHRVIIWLWD 958
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ +er++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+Y
   Q: 959  ILaSDFTPDERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPNY 1045
           **99*************************************************************8888****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k+il+ekL+yAi++++gFels
   Q: 1046 SKKSILREKLRYAISMNTGFELS 1068
           ********************985 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MFTVSQTSRA WFIDRTRQAR EERLVQKERE RAAVEIQAHV RSFLCRRQLH RDIRKEIDEF 60
LQGGDSESSK RSALYIFKIA RKLLFLFRIK EDKERFEKLC RCILSSMDAE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCACTG TATCTCAGAC CTCGAGAGCA TGGTTTATCG ACAGAACCCG GCAGGCACGA 60
GAAGAAAGGC TGGTTCAGAA GGAACGGGAG CGCGCAGCTG TGGAGATCCA GGCCCACGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.72	5.00e-107	382.00
IUUC-Aml-002107	Ailuropoda melanoleuca	95.32	0.00e+00	2072.00
IUUC-Atr-003017	Amborella trichopoda	38.65	4.00e-111	396.00
IUUC-Apl-003328	Anas platyrhynchos	87.84	0.00e+00	1856.00
IUUC-Aly-005794	Arabidopsis lyrata	39.29	3.00e-110	393.00
IUUC-Ath-007269	Arabidopsis thaliana	39.64	5.00e-113	402.00
IUUC-Bta-013547	Bos taurus	94.85	0.00e+00	2085.00
IUUC-Bdi-014502	Brachypodium distachyon	39.32	5.00e-111	395.00
IUUC-Bol-015093	Brassica oleracea	40.00	4.00e-113	402.00
IUUC-Bra-016722	Brassica rapa	40.36	5.00e-115	409.00
IUUC-Cel-018447	Caenorhabditis elegans	37.94	0.00e+00	685.00
IUUC-Cja-019855	Callithrix jacchus	95.32	0.00e+00	2070.00
IUUC-Cfa-020066	Canis familiaris	95.08	0.00e+00	2049.00
IUUC-Csa-023579	Chlorocebus sabaeus	95.41	0.00e+00	2072.00
IUUC-Cho-024430	Choloepus hoffmanni	84.62	0.00e+00	1524.00
IUUC-Cin-025750	Ciona intestinalis	47.03	0.00e+00	969.00
IUUC-Csv-026016	Ciona savignyi	48.13	0.00e+00	1028.00
IUUC-Dre-028271	Danio rerio	81.50	0.00e+00	1759.00
IUUC-Dno-029054	Dasypus novemcinctus	94.66	0.00e+00	2055.00
IUUC-Dor-030938	Dipodomys ordii	87.08	0.00e+00	1857.00
IUUC-Dme-031602	Drosophila melanogaster	48.52	0.00e+00	969.00
IUUC-Ete-033041	Echinops telfairi	75.64	0.00e+00	1359.00
IUUC-Eca-034411	Equus caballus	95.13	0.00e+00	2043.00
IUUC-Eeu-035201	Erinaceus europaeus	84.48	0.00e+00	804.00
IUUC-Fca-036594	Felis catus	94.10	0.00e+00	2033.00
IUUC-Fal-037317	Ficedula albicollis	84.04	0.00e+00	1864.00
IUUC-Gmo-039412	Gadus morhua	77.84	0.00e+00	1724.00
IUUC-Gga-040149	Gallus gallus	87.66	0.00e+00	1883.00
IUUC-Gac-042088	Gasterosteus aculeatus	80.60	0.00e+00	1806.00
IUUC-Gma-042728	Glycine max	41.56	9.00e-113	401.00
IUUC-Ggo-045279	Gorilla gorilla	95.22	0.00e+00	2070.00
IUUC-Hsa-045660	Homo sapiens	94.94	0.00e+00	2065.00
IUUC-Hvu-047770	Hordeum vulgare	36.82	9.00e-108	384.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	93.79	0.00e+00	1055.00
IUUC-Lch-050664	Latimeria chalumnae	81.98	0.00e+00	1813.00
IUUC-Lpe-050755	Leersia perrieri	37.39	1.00e-99	357.00
IUUC-Loc-052791	Lepisosteus oculatus	82.59	0.00e+00	1785.00
IUUC-Laf-053902	Loxodonta africana	95.04	0.00e+00	2067.00
IUUC-Mcc-054730	Macaca mulatta	95.32	0.00e+00	2071.00
IUUC-Meu-056527	Macropus eugenii	79.76	0.00e+00	1673.00
IUUC-Mtr-057671	Medicago truncatula	40.14	9.00e-113	401.00
IUUC-Mga-059260	Meleagris gallopavo	87.31	0.00e+00	1880.00
IUUC-Mmr-060804	Microcebus murinus	93.45	0.00e+00	1987.00
IUUC-Mdo-062575	Monodelphis domestica	83.38	0.00e+00	1781.00
IUUC-Mmu-063636	Mus musculus	91.03	0.00e+00	1939.00
IUUC-Mac-064989	Musa acuminata	39.54	2.00e-108	387.00
IUUC-Mpu-066677	Mustela putorius furo	94.73	0.00e+00	1933.00
IUUC-Mlu-067952	Myotis lucifugus	93.83	0.00e+00	1971.00
IUUC-Nle-069153	Nomascus leucogenys	95.22	0.00e+00	2068.00
IUUC-Opr-070554	Ochotona princeps	93.26	0.00e+00	1863.00
IUUC-Ont-071372	Oreochromis niloticus	81.57	0.00e+00	1785.00
IUUC-Oan-073327	Ornithorhynchus anatinus	71.02	0.00e+00	734.00
IUUC-Ocu-074183	Oryctolagus cuniculus	93.74	0.00e+00	2019.00
IUUC-Oba-075006	Oryza barthii	37.03	2.00e-110	393.00
IUUC-Obr-076320	Oryza brachyantha	39.61	2.00e-110	394.00
IUUC-Ogl-077093	Oryza glaberrima	35.28	2.00e-110	394.00
IUUC-Ogu-078947	Oryza glumaepatula	37.12	1.00e-110	394.00
IUUC-Oin-080058	Oryza indica	35.37	3.00e-110	393.00
IUUC-Olo-080475	Oryza longistaminata	37.28	1.00e-110	394.00
IUUC-Ome-081741	Oryza meridionalis	34.68	8.00e-103	368.00
IUUC-Oni-082385	Oryza nivara	37.12	1.00e-110	394.00
IUUC-Opu-083529	Oryza punctata	39.17	3.00e-110	393.00
IUUC-Oru-084554	Oryza rufipogon	34.91	7.00e-98	352.00
IUUC-Osa-085355	Oryza sativa	37.28	1.00e-110	394.00
IUUC-Ola-087337	Oryzias latipes	81.01	0.00e+00	1731.00
IUUC-Oga-088342	Otolemur garnettii	94.57	0.00e+00	1970.00
IUUC-Oar-090234	Ovis aries	94.42	0.00e+00	2051.00
IUUC-Ptr-091661	Pan troglodytes	95.32	0.00e+00	2072.00
IUUC-Pan-092728	Papio anubis	95.14	0.00e+00	2068.00
IUUC-Psi-093251	Pelodiscus sinensis	87.29	0.00e+00	1744.00
IUUC-Pma-094195	Petromyzon marinus	69.55	0.00e+00	1442.00
IUUC-Ppa-095544	Physcomitrella patens	38.20	5.00e-111	396.00
IUUC-Pfo-097472	Poecilia formosa	81.20	0.00e+00	1792.00
IUUC-Pab-098570	Pongo abelii	95.13	0.00e+00	2070.00
IUUC-Pca-100110	Procavia capensis	82.40	0.00e+00	1722.00
IUUC-Ppe-101281	Prunus persica	39.36	1.00e-108	388.00
IUUC-Pva-102887	Pteropus vampyrus	89.71	0.00e+00	1913.00
IUUC-Rno-106028	Rattus norvegicus	87.86	0.00e+00	1831.00
IUUC-Sha-107331	Sarcophilus harrisii	84.98	0.00e+00	1809.00
IUUC-Smo-109488	Selaginella moellendorffii	36.96	1.00e-106	381.00
IUUC-Sit-109811	Setaria italica	35.95	3.00e-112	399.00
IUUC-Sly-111362	Solanum lycopersicum	35.50	9.00e-101	361.00
IUUC-Sar-113287	Sorex araneus	83.84	0.00e+00	720.00
IUUC-Sbi-114433	Sorghum bicolor	36.14	9.00e-112	398.00
IUUC-Ssc-116103	Sus scrofa	95.42	0.00e+00	2045.00
IUUC-Tgu-117275	Taeniopygia guttata	87.38	0.00e+00	1874.00
IUUC-Tru-118681	Takifugu rubripes	80.17	0.00e+00	1800.00
IUUC-Tsy-118985	Tarsius syrichta	91.21	0.00e+00	1033.00
IUUC-Tni-120850	Tetraodon nigroviridis	91.73	0.00e+00	777.00
IUUC-Tca-121770	Theobroma cacao	39.54	9.00e-113	401.00
IUUC-Tae-125466	Triticum aestivum	36.82	2.00e-108	387.00
IUUC-Tur-126086	Triticum urartu	39.72	3.00e-106	380.00
IUUC-Tbe-127461	Tupaia belangeri	90.45	0.00e+00	1885.00
IUUC-Ttr-129269	Tursiops truncatus	94.76	0.00e+00	2029.00
IUUC-Vpa-130523	Vicugna pacos	80.46	5.00e-124	439.00
IUUC-Vvi-131524	Vitis vinifera	39.22	1.00e-109	391.00
IUUC-Xtr-132146	Xenopus tropicalis	83.40	0.00e+00	1838.00
IUUC-Xma-133526	Xiphophorus maculatus	81.10	0.00e+00	1790.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence