iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025156

UUCD1 version

UUC-CiI-00387

Ensembl Protein ID

ENSCINP00000028278.2

UniProt Accession

F6Z7E0; F6Z7E0_CIOIN

Protein Name

Katanin p80 WD40 repeat-containing subunit B1; p80 katanin

Gene Name

KATNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000016265.2	ENSCINT00000028524.2	ENSCINP00000028278.2
ENSCING00000016265.2	ENSCINT00000028526.2	ENSCINP00000028280.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-33	113.7	143	181
UBD/Beta-Prp	9.10e-52	175.9	6	148

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+dsv+c++f +d + + s s+D+t+k+WD++ g+ll+
   Q: 143  GHEDSVNCVQFsPDgRWIGSVSNDKTCKLWDITAGKLLH 181
           8***********99999******************9987 PP

UBD/Beta-Prp

   S: 124  etgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           +t ++l+  + gh +vv+++++ +++ +++++G+ D++v++W + + +++ tl+   t++v+ l+f+s+ +++ +gs+ g +++w+l++
   Q: 6    KTTWKLQ-EFVGHGSVVTSATLGKKSgRVMATGGEDGKVNMWHVGSPNCIMTLSP-LTSAVETLQFNSSEEFVCAGSRSGALRIWNLSA 92
           5667777.88899999999999998889999999999999999999999999987.999999999999999999999999999999999 PP
   S: 212  gecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           +++vr+l+gh++ v+sv+f++ ++++ sgs+D  +r+Wd+r + ++ t+++h++sv
   Q: 93   SKVVRQLTGHKAAVRSVDFHSYGDFVTSGSDDHKVRMWDIRRKGCIFTYKGHEDSV 148
           99999999999999999999999999999999999999999999999999998876 PP

Organism

Ciona intestinalis

Functional Description
(View)

Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.

Protein Sequence
(Fasta)

MASSTKTTWK LQEFVGHGSV VTSATLGKKS GRVMATGGED GKVNMWHVGS PNCIMTLSPL 60
TSAVETLQFN SSEEFVCAGS RSGALRIWNL SASKVVRQLT GHKAAVRSVD FHSYGDFVTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCAAACTTA TTATAAGCAC ATTTTATAAA GTTTGTTGCT GTGGTTTATT GAACAATTTG 60
TTGCCTGCAT GCTGCATACG GGGTGGGTTG ATTCGTAATT TTCGTTATAT TTGGATTGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0007067--P:mitotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	44.48	6.00e-75	275.00
IUUC-Aml-002187	Ailuropoda melanoleuca	39.34	2.00e-141	494.00
IUUC-Atr-002899	Amborella trichopoda	47.59	1.00e-85	309.00
IUUC-Apl-003305	Anas platyrhynchos	39.31	3.00e-146	510.00
IUUC-Aca-004635	Anolis carolinensis	42.43	1.00e-138	485.00
IUUC-Aly-006226	Arabidopsis lyrata	45.79	9.00e-85	306.00
IUUC-Ath-007323	Arabidopsis thaliana	45.79	1.00e-84	306.00
IUUC-Ame-010870	Astyanax mexicanus	35.29	6.00e-49	186.00
IUUC-Bta-012527	Bos taurus	41.41	2.00e-152	531.00
IUUC-Bdi-014652	Brachypodium distachyon	46.18	8.00e-87	313.00
IUUC-Bol-015355	Brassica oleracea	44.59	6.00e-84	304.00
IUUC-Bra-017265	Brassica rapa	44.59	8.00e-84	304.00
IUUC-Cja-019706	Callithrix jacchus	42.11	3.00e-143	500.00
IUUC-Cfa-020139	Canis familiaris	35.08	3.00e-87	314.00
IUUC-Cpo-021710	Cavia porcellus	42.56	2.00e-150	524.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	36.24	4.00e-55	208.00
IUUC-Csa-023546	Chlorocebus sabaeus	40.90	1.00e-137	481.00
IUUC-Csv-025962	Ciona savignyi	83.16	6.00e-157	545.00
IUUC-Dre-028215	Danio rerio	47.68	1.00e-91	329.00
IUUC-Dno-029314	Dasypus novemcinctus	41.05	4.00e-143	500.00
IUUC-Dor-030482	Dipodomys ordii	42.04	7.00e-155	539.00
IUUC-Dme-032188	Drosophila melanogaster	36.64	4.00e-52	198.00
IUUC-Eca-034143	Equus caballus	40.81	3.00e-145	507.00
IUUC-Fca-035924	Felis catus	41.65	2.00e-149	521.00
IUUC-Fal-037387	Ficedula albicollis	41.72	2.00e-148	518.00
IUUC-Gmo-038692	Gadus morhua	40.72	9.00e-93	333.00
IUUC-Gga-040597	Gallus gallus	41.55	3.00e-150	524.00
IUUC-Gac-042004	Gasterosteus aculeatus	36.47	1.00e-132	465.00
IUUC-Gma-044134	Glycine max	46.31	1.00e-82	299.00
IUUC-Ggo-044761	Gorilla gorilla	41.20	6.00e-142	496.00
IUUC-Hsa-045698	Homo sapiens	41.05	6.00e-143	499.00
IUUC-Hvu-047649	Hordeum vulgare	46.51	1.00e-87	316.00
IUUC-Itr-048697	Ictidomys tridecemlineatus	42.79	2.00e-149	521.00
IUUC-Lch-049674	Latimeria chalumnae	38.80	1.00e-140	492.00
IUUC-Lpe-051554	Leersia perrieri	46.84	1.00e-88	320.00
IUUC-Loc-052623	Lepisosteus oculatus	40.43	1.00e-144	505.00
IUUC-Laf-054587	Loxodonta africana	41.11	3.00e-148	517.00
IUUC-Mcc-055851	Macaca mulatta	41.20	6.00e-142	496.00
IUUC-Meu-056704	Macropus eugenii	42.34	4.00e-154	536.00
IUUC-Mtr-058053	Medicago truncatula	46.31	1.00e-87	315.00
IUUC-Mga-059608	Meleagris gallopavo	40.96	6.00e-148	516.00
IUUC-Mmr-061154	Microcebus murinus	41.20	1.00e-147	515.00
IUUC-Mdo-062365	Monodelphis domestica	40.66	1.00e-140	492.00
IUUC-Mmu-063754	Mus musculus	41.87	5.00e-151	526.00
IUUC-Mac-065100	Musa acuminata	47.08	2.00e-85	308.00
IUUC-Mpu-066245	Mustela putorius furo	41.35	2.00e-145	507.00
IUUC-Mlu-067692	Myotis lucifugus	41.44	2.00e-150	524.00
IUUC-Nle-070051	Nomascus leucogenys	40.84	7.00e-142	496.00
IUUC-Opr-070855	Ochotona princeps	42.19	6.00e-151	526.00
IUUC-Ont-071883	Oreochromis niloticus	44.70	6.00e-83	300.00
IUUC-Oan-073293	Ornithorhynchus anatinus	43.02	7.00e-140	489.00
IUUC-Ocu-074644	Oryctolagus cuniculus	42.56	5.00e-153	533.00
IUUC-Oba-075448	Oryza barthii	46.51	1.00e-88	320.00
IUUC-Obr-076385	Oryza brachyantha	46.51	1.00e-88	319.00
IUUC-Ogl-077427	Oryza glaberrima	46.51	8.00e-89	320.00
IUUC-Ogu-079022	Oryza glumaepatula	43.14	1.00e-82	300.00
IUUC-Oin-079811	Oryza indica	44.41	1.00e-85	310.00
IUUC-Olo-080245	Oryza longistaminata	44.41	1.00e-85	309.00
IUUC-Ome-081239	Oryza meridionalis	46.39	3.00e-85	308.00
IUUC-Oni-082640	Oryza nivara	46.51	1.00e-88	320.00
IUUC-Opu-083748	Oryza punctata	46.84	3.00e-89	321.00
IUUC-Oru-084609	Oryza rufipogon	46.51	1.00e-88	320.00
IUUC-Osa-086267	Oryza sativa	43.14	2.00e-82	298.00
IUUC-Ola-087483	Oryzias latipes	33.39	2.00e-102	365.00
IUUC-Oga-087964	Otolemur garnettii	41.89	5.00e-152	530.00
IUUC-Oar-089483	Ovis aries	40.90	4.00e-145	506.00
IUUC-Ptr-091387	Pan troglodytes	41.20	2.00e-143	501.00
IUUC-Pan-092623	Papio anubis	41.20	6.00e-142	496.00
IUUC-Psi-093830	Pelodiscus sinensis	42.62	7.00e-150	522.00
IUUC-Ppa-095379	Physcomitrella patens	49.83	1.00e-83	303.00
IUUC-Pfo-096755	Poecilia formosa	34.76	3.00e-127	447.00
IUUC-Pab-097564	Pongo abelii	39.97	7.00e-124	436.00
IUUC-Pop-099489	Populus trichocarpa	47.16	3.00e-86	311.00
IUUC-Pca-100357	Procavia capensis	54.90	1.00e-73	269.00
IUUC-Ppe-101237	Prunus persica	46.98	9.00e-88	316.00
IUUC-Pva-102397	Pteropus vampyrus	39.91	3.00e-140	491.00
IUUC-Rno-105349	Rattus norvegicus	42.26	7.00e-155	539.00
IUUC-Smo-109558	Selaginella moellendorffii	46.10	9.00e-82	296.00
IUUC-Sit-110360	Setaria italica	47.51	2.00e-89	322.00
IUUC-Sly-111307	Solanum lycopersicum	46.15	1.00e-81	296.00
IUUC-Stu-112053	Solanum tuberosum	44.48	9.00e-85	306.00
IUUC-Sar-112953	Sorex araneus	38.26	6.00e-47	180.00
IUUC-Sbi-114389	Sorghum bicolor	42.95	1.00e-79	290.00
IUUC-Ssc-115949	Sus scrofa	37.74	3.00e-97	347.00
IUUC-Tgu-117461	Taeniopygia guttata	40.92	9.00e-151	525.00
IUUC-Tru-117865	Takifugu rubripes	35.90	2.00e-130	458.00
IUUC-Tsy-119036	Tarsius syrichta	55.83	2.00e-38	152.00
IUUC-Tni-120903	Tetraodon nigroviridis	36.85	2.00e-130	458.00
IUUC-Tca-121185	Theobroma cacao	45.97	1.00e-85	310.00
IUUC-Tae-125307	Triticum aestivum	46.18	4.00e-87	315.00
IUUC-Tur-126181	Triticum urartu	42.19	2.00e-80	292.00
IUUC-Tbe-127518	Tupaia belangeri	33.76	8.00e-63	233.00
IUUC-Ttr-128172	Tursiops truncatus	42.11	2.00e-148	518.00
IUUC-Vvi-131489	Vitis vinifera	46.98	4.00e-87	314.00
IUUC-Xtr-132915	Xenopus tropicalis	42.61	3.00e-146	510.00
IUUC-Xma-134133	Xiphophorus maculatus	40.63	2.00e-82	298.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence