iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059575

UUCD1 version

UUC-MeG-00844

Ensembl Protein ID

ENSMGAP00000012498.2

UniProt Accession

G1NH68; G1NH68_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000011913.2	ENSMGAT00000013394.2	ENSMGAP00000012498.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.90e-99	331.2	39	368

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l+ +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 39   FGLVNFGNTCYCNSVLQALYFCRPFRENVLS-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 120
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l   ++++k+e+++ + ++ ++++ e+++k++ ++++++Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 121  MQQDAHEFLNYLLNTIADIL---QEEKKQEKQNGKLKNGNMNEAEENNKQELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 206
           ********************...33444445455555566666778888888************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 207  EQNT-----SITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 288
           ****.....9**********************************************************************55555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts  ++++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 289  TSG-DAVNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 368
           774.45556****************************.888*******************999*****************97 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

EVCGGRTTVV VTCSLQGTNA SALEKDIGPE QFPINEHYFG LVNFGNTCYC NSVLQALYFC 60
RPFRENVLSY KAQQKKKENL LTCLADLFHS IATQKKKVGV IPPKKFISRL RKENDLFDNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGTGTGTG GGGGGAGAAC CACTGTTGTT GTGACCTGTT CACTTCAAGT CAGCCATCAT 60
CAGAGCACCT AGATCAGGCC AGCTTCACTA CCTACAACTG CAAATATTTG TGTTGGCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008343--P:adult feeding behavior
GO:0001662--P:behavioral fear response
GO:0048149--P:behavioral response to ethanol
GO:0016579--P:protein deubiquitination
GO:0032228--P:regulation of synaptic transmission, GABAergic
GO:0060013--P:righting reflex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000193	Aegilops tauschii	59.07	2.00e-123	435.00
IUUC-Aml-002353	Ailuropoda melanoleuca	96.95	0.00e+00	689.00
IUUC-Atr-002650	Amborella trichopoda	59.45	3.00e-124	437.00
IUUC-Apl-003380	Anas platyrhynchos	99.72	0.00e+00	698.00
IUUC-Aca-005031	Anolis carolinensis	95.86	0.00e+00	732.00
IUUC-Aly-005830	Arabidopsis lyrata	58.70	2.00e-121	428.00
IUUC-Ath-006663	Arabidopsis thaliana	59.23	1.00e-124	439.00
IUUC-Ame-010862	Astyanax mexicanus	92.88	0.00e+00	702.00
IUUC-Bta-013023	Bos taurus	98.31	0.00e+00	689.00
IUUC-Bdi-014008	Brachypodium distachyon	60.44	5.00e-125	440.00
IUUC-Bra-017483	Brassica rapa	59.94	3.00e-124	437.00
IUUC-Cel-018379	Caenorhabditis elegans	61.92	7.00e-145	506.00
IUUC-Cja-018956	Callithrix jacchus	98.04	0.00e+00	688.00
IUUC-Cfa-021064	Canis familiaris	97.47	0.00e+00	680.00
IUUC-Cpo-022443	Cavia porcellus	98.03	0.00e+00	689.00
IUUC-Csa-023841	Chlorocebus sabaeus	96.69	0.00e+00	689.00
IUUC-Cne-026900	Cryptococcus neoformans	42.28	1.00e-60	227.00
IUUC-Dre-028230	Danio rerio	92.35	0.00e+00	699.00
IUUC-Dno-029209	Dasypus novemcinctus	97.77	0.00e+00	687.00
IUUC-Dme-032038	Drosophila melanogaster	81.28	3.00e-100	358.00
IUUC-Eca-033721	Equus caballus	98.59	0.00e+00	688.00
IUUC-Eeu-034916	Erinaceus europaeus	97.28	1.00e-159	554.00
IUUC-Fca-036299	Felis catus	98.31	0.00e+00	689.00
IUUC-Fox-037682	Fusarium oxysporum	42.01	4.00e-73	269.00
IUUC-Fso-038299	Fusarium solani	37.07	3.00e-74	272.00
IUUC-Gmo-038611	Gadus morhua	94.63	0.00e+00	694.00
IUUC-Gga-041157	Gallus gallus	98.07	0.00e+00	698.00
IUUC-Gac-041764	Gasterosteus aculeatus	96.06	0.00e+00	702.00
IUUC-Gma-042927	Glycine max	60.82	5.00e-126	443.00
IUUC-Ggo-044659	Gorilla gorilla	98.59	0.00e+00	686.00
IUUC-Hsa-046156	Homo sapiens	96.69	0.00e+00	689.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	96.69	0.00e+00	689.00
IUUC-Kpa-049250	Komagataella pastoris	44.83	2.00e-69	256.00
IUUC-Lch-049969	Latimeria chalumnae	94.75	0.00e+00	658.00
IUUC-Lpe-051368	Leersia perrieri	59.34	2.00e-121	428.00
IUUC-Loc-052479	Lepisosteus oculatus	89.78	0.00e+00	668.00
IUUC-Laf-054085	Loxodonta africana	96.69	0.00e+00	689.00
IUUC-Mcc-055566	Macaca mulatta	97.23	0.00e+00	690.00
IUUC-Mtr-057715	Medicago truncatula	60.27	3.00e-126	444.00
IUUC-Mla-059142	Melampsora laricipopulina	53.40	1.00e-94	340.00
IUUC-Mvi-060357	Microbotryum violaceum	53.96	4.00e-78	286.00
IUUC-Mdo-062579	Monodelphis domestica	96.69	0.00e+00	688.00
IUUC-Mmu-063611	Mus musculus	96.69	0.00e+00	689.00
IUUC-Mac-065323	Musa acuminata	60.28	2.00e-122	431.00
IUUC-Mpu-066038	Mustela putorius furo	98.03	0.00e+00	688.00
IUUC-Mlu-068183	Myotis lucifugus	97.23	0.00e+00	691.00
IUUC-Nle-069330	Nomascus leucogenys	96.69	0.00e+00	689.00
IUUC-Opr-070980	Ochotona princeps	98.31	0.00e+00	686.00
IUUC-Ont-072134	Oreochromis niloticus	93.70	0.00e+00	709.00
IUUC-Oan-073583	Ornithorhynchus anatinus	93.22	0.00e+00	681.00
IUUC-Ocu-074923	Oryctolagus cuniculus	98.31	0.00e+00	689.00
IUUC-Oba-075220	Oryza barthii	59.62	3.00e-122	431.00
IUUC-Obr-076208	Oryza brachyantha	56.83	2.00e-118	418.00
IUUC-Ogl-077216	Oryza glaberrima	59.62	3.00e-122	431.00
IUUC-Ogu-078836	Oryza glumaepatula	59.62	3.00e-122	431.00
IUUC-Oin-079522	Oryza indica	59.62	3.00e-122	431.00
IUUC-Olo-080882	Oryza longistaminata	59.62	3.00e-122	431.00
IUUC-Ome-081549	Oryza meridionalis	59.62	3.00e-122	431.00
IUUC-Oni-082982	Oryza nivara	59.62	3.00e-122	431.00
IUUC-Opu-083532	Oryza punctata	59.62	3.00e-122	431.00
IUUC-Oru-084568	Oryza rufipogon	59.62	3.00e-122	431.00
IUUC-Osa-085299	Oryza sativa	59.62	3.00e-122	431.00
IUUC-Ola-086546	Oryzias latipes	95.00	0.00e+00	708.00
IUUC-Oga-088073	Otolemur garnettii	98.59	0.00e+00	688.00
IUUC-Oar-089248	Ovis aries	98.32	0.00e+00	693.00
IUUC-Ptr-090814	Pan troglodytes	96.69	0.00e+00	689.00
IUUC-Pan-091753	Papio anubis	96.69	0.00e+00	689.00
IUUC-Psi-094012	Pelodiscus sinensis	99.16	0.00e+00	696.00
IUUC-Ppa-095415	Physcomitrella patens	58.65	1.00e-125	442.00
IUUC-Pfo-097369	Poecilia formosa	93.70	0.00e+00	709.00
IUUC-Pab-098594	Pongo abelii	98.59	0.00e+00	688.00
IUUC-Pop-099798	Populus trichocarpa	59.73	5.00e-125	440.00
IUUC-Pca-100913	Procavia capensis	82.49	3.00e-156	544.00
IUUC-Ppe-101474	Prunus persica	60.00	1.00e-125	442.00
IUUC-Pva-102892	Pteropus vampyrus	98.03	0.00e+00	687.00
IUUC-Rno-104909	Rattus norvegicus	96.41	0.00e+00	687.00
IUUC-Sce-106367	Saccharomyces cerevisiae	37.63	1.00e-55	211.00
IUUC-Sha-107400	Sarcophilus harrisii	97.49	0.00e+00	689.00
IUUC-Smo-109064	Selaginella moellendorffii	59.94	4.00e-120	424.00
IUUC-Sit-110819	Setaria italica	59.62	3.00e-123	434.00
IUUC-Sly-111210	Solanum lycopersicum	59.62	3.00e-125	440.00
IUUC-Stu-112398	Solanum tuberosum	59.78	1.00e-125	442.00
IUUC-Sbi-114724	Sorghum bicolor	59.34	5.00e-123	433.00
IUUC-Ssc-115550	Sus scrofa	98.59	0.00e+00	687.00
IUUC-Tgu-116800	Taeniopygia guttata	98.07	0.00e+00	698.00
IUUC-Tru-118212	Takifugu rubripes	93.70	0.00e+00	711.00
IUUC-Tni-120071	Tetraodon nigroviridis	93.70	0.00e+00	711.00
IUUC-Tca-121329	Theobroma cacao	59.73	1.00e-125	442.00
IUUC-Tae-124807	Triticum aestivum	59.34	3.00e-124	437.00
IUUC-Tur-126563	Triticum urartu	59.34	3.00e-124	437.00
IUUC-Tme-126890	Tuber melanosporum	46.49	1.00e-90	327.00
IUUC-Uma-129409	Ustilago maydis	48.78	4.00e-81	296.00
IUUC-Vpa-130590	Vicugna pacos	94.07	0.00e+00	641.00
IUUC-Vvi-131371	Vitis vinifera	59.84	3.00e-125	441.00
IUUC-Xma-133111	Xiphophorus maculatus	93.97	0.00e+00	709.00
IUUC-Yli-134632	Yarrowia lipolytica	44.00	1.00e-79	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence