iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006695

UUCD1 version

UUC-ArT-01632

Ensembl Protein ID

AT3G55380.2

UniProt Accession

P42747; Q4TYZ6; UBC14_ARATH

Genbank Protein ID

CAA51200.1; AAC49323.1; AAY44854.1; CAB75896.1; AEE79376.1; AAM51337.1; AAK76557.1; AAM63492.1; CAA79212.1

Protein Name

Ubiquitin-conjugating enzyme E2 14; E2 ubiquitin-conjugating enzyme 14; TAYO29; UbcAt3; Ubiquitin carrier protein 14; Ubiquitin-protein ligase 14

Genbank Nucleotide ID

X72625; U33759; DQ027028; AL132975; CP002686; AY117262; AY045883; AY086490; Z18513

Gene Name

UBC14; UBC3; UBC7; At3g55380; T22E16.40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G55380	AT3G55380.1	AT3G55380.1
AT3G55380	AT3G55380.2	AT3G55380.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Post-translational Modifications (PTMs)
UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.50e-45	154.1	10	130

Active Site

Position(s)	Description	Evidence
90	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........e 88
           l+k+lk+l k+p++g+sa++vde+++++w+v i+Gp+dt Yegg+F++ ++fpe+YP++PP+v+f+++++hPnvy++GkvC+sil+            
   Q: 10   LQKQLKDLCKKPVDGFSAGLVDEKNVFQWSVSIMGPPDTLYEGGFFNAIMSFPENYPVSPPTVTFTSEMWHPNVYSDGKVCISILHppgddphgyelA 107
           799**********************************************************************************989999999*999 PP
   S: 89   eekWspalsv..esvllsiqsll 109
           +e+W+p++++  ++ + si sl 
   Q: 108  SERWTPVHTLveTDMFCSILSLY 130
           ******99982234566776665 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Involved in the formation of multiubiquitin chains. Signal the protein for selective degradation.

Protein Sequence
(Fasta)

MANNQASLLL QKQLKDLCKK PVDGFSAGLV DEKNVFQWSV SIMGPPDTLY EGGFFNAIMS 60
FPENYPVSPP TVTFTSEMWH PNVYSDGKVC ISILHPPGDD PHGYELASER WTPVHTLVET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAGTAGTA AAAATAATAT CGAGACGAGA CGGGTTTGTT TCTTCTCTCT ATCTCTATAT 60
CTACCAAAAT CCTTTGCCCC CCGAATCTAG TTCTCTCGAT CGACCCTGTG ACGATGGCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0000209--P:protein polyubiquitination

KEGG

ath:AT3G55380

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence