iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053975

UUCD1 version

UUC-LoA-00723

Ensembl Protein ID

ENSLAFP00000019156.1

UniProt Accession

G3TU98; G3TU98_LOXAF

Protein Name

Uncharacterized protein

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000031490.1	ENSLAFT00000029187.1	ENSLAFP00000020444.1
ENSLAFG00000031490.1	ENSLAFT00000030528.1	ENSLAFP00000019156.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	86.32	0.00e+00	1269.00	IUUC-Hsa-046484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MHPLGLCNNN DEEDWYDYGW VGVVKLEQPE LDPKPCLTVL GKAKRAVQRG ATAVIFDVSE 60
NPEAIDQLNQ GSEDPLKRPV VYVKGADAIK LMNIVNKQKV ARARIQHRPP RQPTEYFDMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACCCAC TGGGCCTGTG TAATAACAAT GATGAAGAAG ACTGGTATGA CTATGGCTGG 60
GTAGGAGTGG TGAAGCTGGA ACAGCCAGAA TTGGACCCAA AACCATGCCT CACTGTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	82.94	0.00e+00	1167.00
IUUC-Apl-004188	Anas platyrhynchos	74.30	0.00e+00	987.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	1.00e-15	75.50
IUUC-Ath-007372	Arabidopsis thaliana	42.68	5.00e-15	73.60
IUUC-Ame-011764	Astyanax mexicanus	63.22	0.00e+00	723.00
IUUC-Bta-012478	Bos taurus	63.44	0.00e+00	635.00
IUUC-Bdi-014783	Brachypodium distachyon	34.65	4.00e-13	68.90
IUUC-Bol-016217	Brassica oleracea	54.00	2.00e-14	71.60
IUUC-Bra-017970	Brassica rapa	40.00	2.00e-14	72.00
IUUC-Cja-019504	Callithrix jacchus	83.99	0.00e+00	1249.00
IUUC-Cfa-020048	Canis familiaris	84.14	0.00e+00	1269.00
IUUC-Cpo-021725	Cavia porcellus	81.75	0.00e+00	1186.00
IUUC-Csa-023586	Chlorocebus sabaeus	83.58	0.00e+00	1211.00
IUUC-Cho-024867	Choloepus hoffmanni	90.20	0.00e+00	679.00
IUUC-Cin-025569	Ciona intestinalis	47.11	2.00e-55	210.00
IUUC-Csv-025869	Ciona savignyi	44.35	2.00e-48	187.00
IUUC-Dre-027553	Danio rerio	64.88	0.00e+00	787.00
IUUC-Dno-029370	Dasypus novemcinctus	84.33	0.00e+00	1195.00
IUUC-Dor-030816	Dipodomys ordii	75.64	0.00e+00	1062.00
IUUC-Ete-033060	Echinops telfairi	73.98	0.00e+00	833.00
IUUC-Eca-034044	Equus caballus	84.62	0.00e+00	1247.00
IUUC-Eeu-034591	Erinaceus europaeus	66.87	9.00e-134	470.00
IUUC-Fca-036000	Felis catus	84.39	0.00e+00	1253.00
IUUC-Fal-037147	Ficedula albicollis	71.53	0.00e+00	1005.00
IUUC-Fox-037731	Fusarium oxysporum	39.33	3.00e-13	68.20
IUUC-Gmo-039099	Gadus morhua	61.52	9.00e-112	397.00
IUUC-Ggr-039947	Gaeumannomyces graminis	30.43	3.00e-11	63.50
IUUC-Gga-041243	Gallus gallus	67.94	0.00e+00	773.00
IUUC-Gac-041340	Gasterosteus aculeatus	49.66	3.00e-115	408.00
IUUC-Gma-044387	Glycine max	47.69	4.00e-16	77.80
IUUC-Ggo-044953	Gorilla gorilla	85.29	0.00e+00	1256.00
IUUC-Hsa-046484	Homo sapiens	85.52	0.00e+00	1266.00
IUUC-Hvu-047249	Hordeum vulgare	43.21	4.00e-13	67.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	82.03	0.00e+00	1214.00
IUUC-Lch-050004	Latimeria chalumnae	59.89	0.00e+00	671.00
IUUC-Lpe-051459	Leersia perrieri	32.23	3.00e-13	69.30
IUUC-Loc-051830	Lepisosteus oculatus	67.34	0.00e+00	779.00
IUUC-Mcc-055302	Macaca mulatta	83.09	0.00e+00	1195.00
IUUC-Meu-056263	Macropus eugenii	75.60	0.00e+00	786.00
IUUC-Mtr-058744	Medicago truncatula	39.56	2.00e-14	71.60
IUUC-Mga-059706	Meleagris gallopavo	71.45	0.00e+00	1006.00
IUUC-Mvi-060267	Microbotryum violaceum	33.33	4.00e-10	60.50
IUUC-Mmr-061372	Microcebus murinus	83.54	0.00e+00	1156.00
IUUC-Mdo-062651	Monodelphis domestica	66.55	0.00e+00	882.00
IUUC-Mmu-064339	Mus musculus	82.48	0.00e+00	1196.00
IUUC-Mac-065574	Musa acuminata	44.16	4.00e-14	70.90
IUUC-Mpu-066211	Mustela putorius furo	82.05	0.00e+00	1176.00
IUUC-Mlu-067058	Myotis lucifugus	85.11	0.00e+00	1190.00
IUUC-Nle-069886	Nomascus leucogenys	85.03	0.00e+00	1241.00
IUUC-Opr-070218	Ochotona princeps	77.49	0.00e+00	1048.00
IUUC-Ont-072483	Oreochromis niloticus	61.47	0.00e+00	762.00
IUUC-Oan-073718	Ornithorhynchus anatinus	71.88	0.00e+00	939.00
IUUC-Ocu-073847	Oryctolagus cuniculus	74.10	0.00e+00	1018.00
IUUC-Oba-075528	Oryza barthii	42.86	2.00e-12	66.60
IUUC-Obr-076466	Oryza brachyantha	45.07	5.00e-14	70.50
IUUC-Ogl-077034	Oryza glaberrima	52.00	2.00e-11	63.50
IUUC-Oin-079182	Oryza indica	52.00	1.00e-11	64.30
IUUC-Olo-080549	Oryza longistaminata	43.66	4.00e-13	68.20
IUUC-Ome-081485	Oryza meridionalis	52.00	9.00e-12	64.30
IUUC-Opu-083993	Oryza punctata	49.09	8.00e-12	64.70
IUUC-Oru-084953	Oryza rufipogon	52.00	1.00e-11	63.90
IUUC-Osa-085734	Oryza sativa	52.00	1.00e-11	63.90
IUUC-Ola-087358	Oryzias latipes	62.39	0.00e+00	762.00
IUUC-Oga-088362	Otolemur garnettii	82.93	0.00e+00	1237.00
IUUC-Oar-090197	Ovis aries	97.97	6.00e-97	348.00
IUUC-Ptr-091350	Pan troglodytes	85.28	0.00e+00	1263.00
IUUC-Pan-091700	Papio anubis	82.97	0.00e+00	1187.00
IUUC-Psi-093301	Pelodiscus sinensis	70.98	0.00e+00	952.00
IUUC-Ppa-095409	Physcomitrella patens	42.25	1.00e-13	70.50
IUUC-Pfo-096917	Poecilia formosa	62.23	0.00e+00	751.00
IUUC-Pab-097932	Pongo abelii	84.93	0.00e+00	1268.00
IUUC-Pop-099640	Populus trichocarpa	56.86	2.00e-15	75.90
IUUC-Pca-101054	Procavia capensis	91.16	0.00e+00	937.00
IUUC-Ppe-102030	Prunus persica	33.85	1.00e-14	73.90
IUUC-Pva-102879	Pteropus vampyrus	84.75	0.00e+00	1262.00
IUUC-Pgr-103645	Puccinia graminis	52.00	4.00e-11	61.20
IUUC-Sha-106507	Sarcophilus harrisii	54.77	5.00e-171	594.00
IUUC-Sit-109802	Setaria italica	52.08	1.00e-12	67.80
IUUC-Sly-111371	Solanum lycopersicum	49.12	1.00e-13	69.30
IUUC-Stu-112010	Solanum tuberosum	46.58	1.00e-13	70.90
IUUC-Sar-113182	Sorex araneus	80.28	7.00e-111	394.00
IUUC-Sbi-114414	Sorghum bicolor	41.03	2.00e-13	68.20
IUUC-Ssc-115966	Sus scrofa	79.18	0.00e+00	1028.00
IUUC-Tgu-116864	Taeniopygia guttata	63.65	0.00e+00	647.00
IUUC-Tru-118502	Takifugu rubripes	61.94	0.00e+00	731.00
IUUC-Tsy-119210	Tarsius syrichta	83.68	0.00e+00	1196.00
IUUC-Tni-120344	Tetraodon nigroviridis	53.68	3.00e-126	445.00
IUUC-Tca-121005	Theobroma cacao	40.00	1.00e-14	73.20
IUUC-Tae-125497	Triticum aestivum	49.15	3.00e-14	72.40
IUUC-Tur-125977	Triticum urartu	45.45	3.00e-14	72.40
IUUC-Tbe-127735	Tupaia belangeri	80.43	1.00e-127	450.00
IUUC-Ttr-128714	Tursiops truncatus	73.94	0.00e+00	968.00
IUUC-Vvi-131280	Vitis vinifera	31.50	5.00e-15	75.10
IUUC-Xtr-132280	Xenopus tropicalis	61.59	0.00e+00	709.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence