iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033842

Ensembl Protein ID

ENSECAP00000001121.1

UniProt Accession

F6TUR2; F6TUR2_HORSE

Protein Name

Uncharacterized protein

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000000227.1	ENSECAT00000001478.1	ENSECAP00000001121.1
ENSECAG00000000227.1	ENSECAT00000001829.1	ENSECAP00000001343.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	82.50	0.00e+00	1921.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

RGEASPTMTS TGQDSTTTRQ RRSRHNPHSP PHDSSVASKR SVKKGATLRS SPNLAEVKKK 60
GRMKKLSQAA DQDLIMGLQG LDLNLEAKTL SGTGLVFDEQ LNEFHCLWDD SFPEGPERLH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAAGTCCC CCGAGGAGCA GGGCTAGTTG AAACGTTAGG GGCGGGATCT GGCCAAGTGA 60
AAGGTGCCGG TCCGGCCTGA TAAGGGGTGG AGTTAAGTGG CTCGTTAAGG GTGGAGTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	42.90	8.00e-73	268.00
IUUC-Aml-002087	Ailuropoda melanoleuca	85.34	0.00e+00	1992.00
IUUC-Atr-002745	Amborella trichopoda	43.75	3.00e-87	315.00
IUUC-Apl-003250	Anas platyrhynchos	43.61	8.00e-82	298.00
IUUC-Aca-004303	Anolis carolinensis	51.00	0.00e+00	1184.00
IUUC-Aly-006432	Arabidopsis lyrata	43.04	3.00e-82	299.00
IUUC-Ath-007355	Arabidopsis thaliana	43.12	1.00e-87	317.00
IUUC-Ago-007972	Ashbya gossypii	40.61	5.00e-82	298.00
IUUC-Acl-008187	Aspergillus clavatus	45.99	5.00e-86	312.00
IUUC-Afl-008399	Aspergillus flavus	48.74	2.00e-49	189.00
IUUC-Afu-008954	Aspergillus fumigatus	41.51	1.00e-74	274.00
IUUC-Ani-009142	Aspergillus nidulans	43.28	3.00e-78	286.00
IUUC-Ang-009522	Aspergillus niger	34.58	2.00e-49	190.00
IUUC-Aor-010069	Aspergillus oryzae	40.70	3.00e-77	282.00
IUUC-Ate-010291	Aspergillus terreus	42.01	1.00e-85	311.00
IUUC-Ame-010780	Astyanax mexicanus	51.05	0.00e+00	794.00
IUUC-Bta-013052	Bos taurus	77.02	0.00e+00	1762.00
IUUC-Bci-013789	Botrytis cinerea	42.37	2.00e-77	284.00
IUUC-Bdi-014007	Brachypodium distachyon	43.18	7.00e-87	315.00
IUUC-Bol-015468	Brassica oleracea	43.72	1.00e-85	310.00
IUUC-Bra-016680	Brassica rapa	43.98	4.00e-86	312.00
IUUC-Cel-018220	Caenorhabditis elegans	38.43	3.00e-150	525.00
IUUC-Cja-019473	Callithrix jacchus	78.94	0.00e+00	1816.00
IUUC-Cfa-020263	Canis familiaris	84.51	0.00e+00	1937.00
IUUC-Cpo-021691	Cavia porcellus	79.19	0.00e+00	1840.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	53.74	1.00e-56	212.00
IUUC-Csa-024223	Chlorocebus sabaeus	82.76	0.00e+00	1920.00
IUUC-Csv-026359	Ciona savignyi	48.59	2.00e-61	229.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	40.31	5.00e-79	288.00
IUUC-Cne-026978	Cryptococcus neoformans	44.18	6.00e-89	322.00
IUUC-Dre-028820	Danio rerio	56.84	0.00e+00	943.00
IUUC-Dno-029160	Dasypus novemcinctus	74.54	0.00e+00	1676.00
IUUC-Dor-030859	Dipodomys ordii	70.58	0.00e+00	1689.00
IUUC-Dse-031186	Dothistroma septosporum	41.71	1.00e-80	294.00
IUUC-Dme-031963	Drosophila melanogaster	45.13	0.00e+00	705.00
IUUC-Ete-032279	Echinops telfairi	68.10	2.00e-161	562.00
IUUC-Eeu-034487	Erinaceus europaeus	79.34	8.00e-162	564.00
IUUC-Fca-036430	Felis catus	84.52	0.00e+00	1939.00
IUUC-Fox-038067	Fusarium oxysporum	41.60	1.00e-81	297.00
IUUC-Fso-038263	Fusarium solani	39.17	1.00e-82	301.00
IUUC-Gmo-038473	Gadus morhua	42.64	6.00e-77	282.00
IUUC-Ggr-040062	Gaeumannomyces graminis	40.96	3.00e-77	283.00
IUUC-Gga-040501	Gallus gallus	43.86	6.00e-82	299.00
IUUC-Gac-042335	Gasterosteus aculeatus	44.39	2.00e-83	303.00
IUUC-Gma-043738	Glycine max	37.52	4.00e-88	318.00
IUUC-Ggo-045022	Gorilla gorilla	82.76	0.00e+00	1913.00
IUUC-Hsa-046904	Homo sapiens	82.67	0.00e+00	1909.00
IUUC-Hvu-047285	Hordeum vulgare	45.82	4.00e-85	308.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	79.87	0.00e+00	1888.00
IUUC-Kpa-049281	Komagataella pastoris	41.43	1.00e-86	313.00
IUUC-Lch-050330	Latimeria chalumnae	47.03	0.00e+00	989.00
IUUC-Lpe-051214	Leersia perrieri	39.07	1.00e-87	317.00
IUUC-Loc-052231	Lepisosteus oculatus	44.27	1.00e-82	301.00
IUUC-Lma-053263	Leptosphaeria maculans	44.76	6.00e-90	325.00
IUUC-Laf-053386	Loxodonta africana	77.92	0.00e+00	1803.00
IUUC-Mcc-055530	Macaca mulatta	82.93	0.00e+00	1911.00
IUUC-Meu-056442	Macropus eugenii	67.88	0.00e+00	975.00
IUUC-Mor-057095	Magnaporthe oryzae	39.36	1.00e-84	307.00
IUUC-Mpo-057389	Magnaporthe poae	41.88	3.00e-75	276.00
IUUC-Mtr-058463	Medicago truncatula	43.73	3.00e-89	322.00
IUUC-Mla-059143	Melampsora laricipopulina	42.63	1.00e-85	310.00
IUUC-Mmr-060637	Microcebus murinus	83.06	0.00e+00	1980.00
IUUC-Mdo-062198	Monodelphis domestica	67.56	0.00e+00	1087.00
IUUC-Mmu-063346	Mus musculus	73.23	0.00e+00	1713.00
IUUC-Mac-064630	Musa acuminata	41.01	4.00e-85	308.00
IUUC-Mpu-065884	Mustela putorius furo	84.24	0.00e+00	1985.00
IUUC-Mlu-068117	Myotis lucifugus	81.99	0.00e+00	1854.00
IUUC-Nfi-068404	Neosartorya fischeri	45.19	9.00e-86	311.00
IUUC-Ncr-068672	Neurospora crassa	41.52	5.00e-82	298.00
IUUC-Nle-069868	Nomascus leucogenys	92.21	0.00e+00	752.00
IUUC-Opr-071074	Ochotona princeps	69.87	0.00e+00	1110.00
IUUC-Ont-072246	Oreochromis niloticus	46.34	0.00e+00	941.00
IUUC-Oan-072911	Ornithorhynchus anatinus	69.72	2.00e-109	390.00
IUUC-Ocu-074627	Oryctolagus cuniculus	80.00	0.00e+00	1906.00
IUUC-Oba-075489	Oryza barthii	46.15	4.00e-86	311.00
IUUC-Obr-076150	Oryza brachyantha	45.99	4.00e-86	312.00
IUUC-Ogl-077437	Oryza glaberrima	43.38	1.00e-86	313.00
IUUC-Ogu-078370	Oryza glumaepatula	43.66	2.00e-87	316.00
IUUC-Oin-079210	Oryza indica	43.66	2.00e-87	316.00
IUUC-Olo-080971	Oryza longistaminata	47.31	2.00e-75	276.00
IUUC-Oni-082031	Oryza nivara	43.66	3.00e-87	316.00
IUUC-Opu-083471	Oryza punctata	45.85	4.00e-86	312.00
IUUC-Oru-084755	Oryza rufipogon	43.66	2.00e-87	316.00
IUUC-Osa-085447	Oryza sativa	43.66	3.00e-87	316.00
IUUC-Ola-087031	Oryzias latipes	44.76	4.00e-82	299.00
IUUC-Oga-089155	Otolemur garnettii	81.63	0.00e+00	1905.00
IUUC-Oar-089620	Ovis aries	77.74	0.00e+00	1785.00
IUUC-Ptr-090812	Pan troglodytes	89.30	0.00e+00	1273.00
IUUC-Pan-092340	Papio anubis	82.59	0.00e+00	1903.00
IUUC-Psi-093734	Pelodiscus sinensis	43.89	9.00e-81	295.00
IUUC-Pma-094386	Petromyzon marinus	54.08	0.00e+00	834.00
IUUC-Pno-095131	Phaeosphaeria nodorum	48.30	2.00e-77	283.00
IUUC-Ppa-095550	Physcomitrella patens	46.01	7.00e-90	325.00
IUUC-Pfo-096110	Poecilia formosa	51.18	0.00e+00	726.00
IUUC-Pab-098422	Pongo abelii	82.24	0.00e+00	1883.00
IUUC-Pop-099174	Populus trichocarpa	41.90	4.00e-83	302.00
IUUC-Pca-100833	Procavia capensis	74.98	0.00e+00	1630.00
IUUC-Ppe-101644	Prunus persica	42.11	4.00e-90	325.00
IUUC-Pva-102410	Pteropus vampyrus	77.82	0.00e+00	1751.00
IUUC-Ptt-103841	Puccinia triticina	40.05	5.00e-83	302.00
IUUC-Pte-104383	Pyrenophora teres	43.58	1.00e-85	311.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	43.90	3.00e-86	313.00
IUUC-Rno-105131	Rattus norvegicus	74.28	0.00e+00	1730.00
IUUC-Sce-106274	Saccharomyces cerevisiae	39.74	9.00e-81	294.00
IUUC-Sha-106661	Sarcophilus harrisii	55.64	0.00e+00	836.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	40.91	4.00e-88	319.00
IUUC-Spo-108300	Schizosaccharomyces pombe	45.48	1.00e-87	317.00
IUUC-Smo-109615	Selaginella moellendorffii	48.94	2.00e-87	316.00
IUUC-Sit-110160	Setaria italica	43.41	2.00e-82	300.00
IUUC-Sly-111164	Solanum lycopersicum	39.67	3.00e-83	302.00
IUUC-Stu-112685	Solanum tuberosum	41.69	3.00e-71	262.00
IUUC-Sar-113692	Sorex araneus	68.23	0.00e+00	803.00
IUUC-Sbi-114301	Sorghum bicolor	46.46	8.00e-82	298.00
IUUC-Sre-115013	Sporisorium reilianum	41.67	2.00e-82	300.00
IUUC-Ssc-115724	Sus scrofa	81.31	0.00e+00	1786.00
IUUC-Tgu-116605	Taeniopygia guttata	49.15	0.00e+00	709.00
IUUC-Tru-117614	Takifugu rubripes	54.81	0.00e+00	861.00
IUUC-Tsy-118807	Tarsius syrichta	71.60	0.00e+00	977.00
IUUC-Tni-119809	Tetraodon nigroviridis	55.89	0.00e+00	815.00
IUUC-Tca-121312	Theobroma cacao	43.19	3.00e-86	313.00
IUUC-Tre-121930	Trichoderma reesei	40.84	2.00e-83	303.00
IUUC-Tvi-122373	Trichoderma virens	42.12	2.00e-83	303.00
IUUC-Tae-123064	Triticum aestivum	41.10	3.00e-79	288.00
IUUC-Tme-127027	Tuber melanosporum	41.96	5.00e-72	265.00
IUUC-Tbe-127675	Tupaia belangeri	59.06	4.00e-106	379.00
IUUC-Ttr-128411	Tursiops truncatus	80.12	0.00e+00	1885.00
IUUC-Uma-129408	Ustilago maydis	47.40	1.00e-76	280.00
IUUC-Vda-129994	Verticillium dahliae	38.94	4.00e-75	275.00
IUUC-Vpa-130525	Vicugna pacos	81.91	2.00e-66	246.00
IUUC-Vvi-131038	Vitis vinifera	42.34	3.00e-87	316.00
IUUC-Xtr-132618	Xenopus tropicalis	56.90	0.00e+00	974.00
IUUC-Xma-133730	Xiphophorus maculatus	56.17	5.00e-152	532.00
IUUC-Yli-134680	Yarrowia lipolytica	37.33	3.00e-85	309.00
IUUC-Zma-135110	Zea mays	43.01	1.00e-82	300.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence