iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006911

UUCD1 version

UUC-ArT-01446

Ensembl Protein ID

AT2G39810.1

UniProt Accession

Q84JU6; O22289; HOS1_ARATH

Genbank Protein ID

AAB87130.1; AEC09734.1; AAO42259.1; AAO63937.1

Protein Name

E3 ubiquitin-protein ligase HOS1; Protein HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 1; RING finger protein HOS1; RING-type E3 ubiquitin transferase HOS1

Genbank Nucleotide ID

AC003000; CP002685; BT004255; BT005517

Gene Name

HOS1; At2g39810; T5I7.11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G39810	AT2G39810.1	AT2G39810.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT	dbPTM
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	21447070; 16702557; 19941154; 23135282

Reviewed

Classification

Family	Identity	E-value	Score	Source Orthology
E3 activity/RING/RING	44.89	0.00e+00	678.00	IUUC-Osa-086280

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of the transcription factor ICE1. Acts as a negative regulator of cold signaling pathways (PubMed:16702557). Probably involved in recruiting the NUP107-160 subcomplex of the nuclear pore complex to chromatin (Probable). Controls flowering time in response to ambient temperatures (16 and 23 degrees Celsius) and intermittent cold, probably via the regulation of FT and TSF levels (PubMed:22960247).

Protein Sequence
(Fasta)

MDTREINGFA SAARSISLPT QPNYSSKPVQ EALKHLASIN LRELCNEAKV ERCRATRDLA 60
SCGRFVNYVL NPCGHASLCT ECCQRCDVCP ICRSTLPKFG DRLRLRLYYE CVEAGLISRT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGACTTGACC CGTTTGAGGA GAAATTCACT CAACAGTGTT TCCTCTCTTC GTCTTCCCTC 60
CCGAGAAAGC TCAACGGAGC CCTAGACTGG TTTTATCACT CTCGCCAACA CCAACCACGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0716--Sensory transduction
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025151--ELYS_dom

Pfam

PF13934--ELYS

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0016567--P:protein ubiquitination
GO:0009966--P:regulation of signal transduction
GO:0009409--P:response to cold
GO:0010228--P:vegetative to reproductive phase transition of meristem

KEGG

ath:AT2G39810

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000377	Aegilops tauschii	42.17	5.00e-107	381.00
IUUC-Atr-003128	Amborella trichopoda	55.43	0.00e+00	781.00
IUUC-Aly-005703	Arabidopsis lyrata	92.46	0.00e+00	1715.00
IUUC-Bdi-014716	Brachypodium distachyon	48.04	0.00e+00	628.00
IUUC-Bol-015719	Brassica oleracea	82.70	0.00e+00	1538.00
IUUC-Bra-017997	Brassica rapa	80.66	0.00e+00	1524.00
IUUC-Cja-019346	Callithrix jacchus	23.00	4.00e-08	54.30
IUUC-Cfa-021184	Canis familiaris	23.00	9.00e-07	50.10
IUUC-Cpo-021809	Cavia porcellus	23.08	4.00e-05	44.70
IUUC-Csa-024229	Chlorocebus sabaeus	22.04	3.00e-06	48.10
IUUC-Eeu-034782	Erinaceus europaeus	24.20	3.00e-07	51.60
IUUC-Fca-036466	Felis catus	23.81	3.00e-06	48.50
IUUC-Gmo-039692	Gadus morhua	21.88	1.00e-05	45.40
IUUC-Gma-044277	Glycine max	51.37	0.00e+00	810.00
IUUC-Hsa-046642	Homo sapiens	23.00	5.00e-07	51.20
IUUC-Hvu-047462	Hordeum vulgare	47.06	0.00e+00	668.00
IUUC-Itr-048971	Ictidomys tridecemlineatus	23.64	8.00e-06	47.00
IUUC-Lpe-051358	Leersia perrieri	44.51	5.00e-167	581.00
IUUC-Loc-052453	Lepisosteus oculatus	20.58	3.00e-07	50.80
IUUC-Mcc-055404	Macaca mulatta	22.04	3.00e-06	48.50
IUUC-Mtr-058237	Medicago truncatula	50.75	0.00e+00	857.00
IUUC-Mla-058918	Melampsora laricipopulina	28.78	6.00e-05	40.80
IUUC-Mmr-061515	Microcebus murinus	23.23	1.00e-05	45.80
IUUC-Mmu-063425	Mus musculus	23.40	1.00e-05	46.20
IUUC-Mac-065210	Musa acuminata	46.61	0.00e+00	724.00
IUUC-Nle-070006	Nomascus leucogenys	23.00	2.00e-07	52.00
IUUC-Oba-075582	Oryza barthii	42.57	7.00e-176	610.00
IUUC-Obr-076132	Oryza brachyantha	42.91	0.00e+00	664.00
IUUC-Ogl-077653	Oryza glaberrima	44.64	0.00e+00	659.00
IUUC-Ogu-078815	Oryza glumaepatula	44.07	0.00e+00	652.00
IUUC-Oin-079544	Oryza indica	33.22	7.00e-78	284.00
IUUC-Olo-080263	Oryza longistaminata	35.83	6.00e-129	454.00
IUUC-Oni-082232	Oryza nivara	43.32	0.00e+00	632.00
IUUC-Opu-083296	Oryza punctata	48.59	8.00e-96	344.00
IUUC-Oru-084438	Oryza rufipogon	43.32	0.00e+00	632.00
IUUC-Osa-086280	Oryza sativa	100.00	0.00e+00	1849.00
IUUC-Olu-087642	Ostreococcus lucimarinus	23.29	9.00e-18	85.90
IUUC-Pan-092702	Papio anubis	22.04	2.00e-06	48.50
IUUC-Ppa-095437	Physcomitrella patens	39.92	3.00e-95	342.00
IUUC-Pab-097569	Pongo abelii	23.00	4.00e-07	51.20
IUUC-Pop-099913	Populus trichocarpa	55.19	0.00e+00	934.00
IUUC-Ppe-102080	Prunus persica	52.88	0.00e+00	911.00
IUUC-Sja-107901	Schizosaccharomyces japonicus	36.84	3.70e-02	31.60
IUUC-Ssl-108458	Sclerotinia sclerotiorum	24.26	2.30e-02	33.10
IUUC-Smo-109433	Selaginella moellendorffii	46.93	1.00e-156	546.00
IUUC-Sit-110519	Setaria italica	50.90	0.00e+00	657.00
IUUC-Sly-111501	Solanum lycopersicum	50.32	0.00e+00	865.00
IUUC-Stu-112823	Solanum tuberosum	50.66	0.00e+00	872.00
IUUC-Sbi-113975	Sorghum bicolor	39.61	5.00e-39	154.00
IUUC-Sre-114890	Sporisorium reilianum	23.24	4.00e-03	36.60
IUUC-Tni-119734	Tetraodon nigroviridis	27.06	5.20e-02	33.50
IUUC-Tca-121088	Theobroma cacao	54.11	0.00e+00	956.00
IUUC-Tvi-122315	Trichoderma virens	42.86	1.50e-01	30.40
IUUC-Tae-123947	Triticum aestivum	48.95	0.00e+00	657.00
IUUC-Tur-126265	Triticum urartu	41.40	9.00e-158	550.00
IUUC-Vvi-130863	Vitis vinifera	52.67	0.00e+00	873.00
IUUC-Xtr-132698	Xenopus tropicalis	23.32	6.00e-08	52.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence