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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106368
UUCD1 version UUC-SaC-00275
Ensembl Protein ID YFR005C
UniProt Accession P43589; D6VTN5; SAD1_YEAST
Genbank Protein ID BAA09244.1; AAT92785.1; DAA12445.1
Protein Name Pre-mRNA-splicing factor SAD1; snRNP assembly-defective protein 1
Genbank Nucleotide ID D50617; AY692766; BK006940
Gene Name SAD1; YFR005C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YFR005C YFR005C YFR005C
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
dbPAFdbPTMUniProtBioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
DUB/USP 29.32 1.00e-44 179.00 IUUC-Hsa-046041
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Promotes the assembly of newly synthesized U4 snRNA into the U4/U6 snRNP particle. Required for splicing of pre-mRNA.
 Promotes the assembly of newly synthesized U4 snRNA into the U4/U6 snRNP particle. Required for splicing of pre-mRNA.
Protein Sequence
(Fasta)
MEVDNKRRHS EDELKQEAVK KIKSQEPNYA YLETVVREKL DFDSEKICCI TLSPLNVYCC 60
LVCGHYYQGR HEKSPAFIHS IDENHHVFLN LTSLKFYMLP QNVQILHDGE VQLLNSIKFA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106368|DUB,USP|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGAGGTTG ATAACAAAAG GAGACATTCA GAAGATGAGT TAAAACAGGA GGCAGTAAAA 60
AAGATAAAGT CTCAGGAACC AAACTATGCC TATCTTGAGA CTGTAGTAAG AGAAAAACTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106368|DUB,USP|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0687--Ribonucleoprotein
KW-0747--Spliceosome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR033809--USP39
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0005634--C:nucleus
GO:0005681--C:spliceosomal complex
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0000398--P:mRNA splicing, via spliceosome
GO:0016579--P:protein deubiquitination
GO:0000245--P:spliceosomal complex assembly
KEGG sce:YFR005C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000483 Aegilops tauschii 28.51 3.00e-40 157.00
IUUC-Aml-001846 Ailuropoda melanoleuca 29.32 3.00e-49 187.00
IUUC-Atr-002758 Amborella trichopoda 28.48 2.00e-40 158.00
IUUC-Apl-003336 Anas platyrhynchos 24.78 1.00e-14 72.40
IUUC-Aca-004846 Anolis carolinensis 30.45 5.00e-49 186.00
IUUC-Aly-005683 Arabidopsis lyrata 27.45 3.00e-37 147.00
IUUC-Ath-007652 Arabidopsis thaliana 27.45 5.00e-36 143.00
IUUC-Ago-007802 Ashbya gossypii 37.86 2.00e-85 307.00
IUUC-Acl-008304 Aspergillus clavatus 28.77 4.00e-48 184.00
IUUC-Afl-008735 Aspergillus flavus 41.32 5.00e-25 107.00
IUUC-Afu-009100 Aspergillus fumigatus 28.83 4.00e-46 177.00
IUUC-Ani-009138 Aspergillus nidulans 29.12 1.00e-48 185.00
IUUC-Ang-009661 Aspergillus niger 29.19 7.00e-49 186.00
IUUC-Aor-010235 Aspergillus oryzae 28.17 2.00e-40 158.00
IUUC-Ate-010346 Aspergillus terreus 26.16 3.00e-29 121.00
IUUC-Ame-011688 Astyanax mexicanus 29.75 1.00e-47 181.00
IUUC-Bgr-011998 Blumeria graminis 32.02 4.00e-59 220.00
IUUC-Bta-013407 Bos taurus 29.32 3.00e-49 187.00
IUUC-Bci-013977 Botrytis cinerea 33.89 2.00e-60 224.00
IUUC-Bdi-014361 Brachypodium distachyon 28.94 3.00e-41 160.00
IUUC-Bol-016317 Brassica oleracea 28.10 2.00e-38 151.00
IUUC-Bra-016694 Brassica rapa 28.89 2.00e-43 167.00
IUUC-Cel-018491 Caenorhabditis elegans 28.54 3.00e-47 181.00
IUUC-Cja-019134 Callithrix jacchus 29.32 3.00e-49 187.00
IUUC-Cfa-020098 Canis familiaris 29.32 3.00e-49 187.00
IUUC-Cpo-021595 Cavia porcellus 29.32 4.00e-49 187.00
IUUC-Cre-022886 Chlamydomonas reinhardtii 26.09 2.00e-05 39.30
IUUC-Csa-024121 Chlorocebus sabaeus 29.32 3.00e-49 187.00
IUUC-Cho-025057 Choloepus hoffmanni 27.57 2.00e-13 68.20
IUUC-Cin-025473 Ciona intestinalis 28.39 4.00e-11 59.30
IUUC-Csv-025815 Ciona savignyi 36.55 1.00e-35 142.00
IUUC-Cgl-026416 Colletotrichum gloeosporioides 32.97 5.00e-63 233.00
IUUC-Cne-026802 Cryptococcus neoformans 31.19 8.00e-48 182.00
IUUC-Dre-027870 Danio rerio 29.47 3.00e-48 184.00
IUUC-Dno-029655 Dasypus novemcinctus 29.32 5.00e-49 186.00
IUUC-Dor-030762 Dipodomys ordii 29.32 4.00e-49 187.00
IUUC-Dse-031441 Dothistroma septosporum 31.51 4.00e-61 226.00
IUUC-Dme-032101 Drosophila melanogaster 30.77 5.00e-54 203.00
IUUC-Ete-032841 Echinops telfairi 39.90 1.00e-35 142.00
IUUC-Eca-033463 Equus caballus 29.32 3.00e-49 187.00
IUUC-Eeu-034438 Erinaceus europaeus 37.31 1.00e-30 125.00
IUUC-Fca-035774 Felis catus 29.32 3.00e-49 187.00
IUUC-Fal-036988 Ficedula albicollis 30.56 6.00e-51 192.00
IUUC-Fox-037895 Fusarium oxysporum 32.46 2.00e-62 231.00
IUUC-Fso-038450 Fusarium solani 33.55 2.00e-62 231.00
IUUC-Gmo-038874 Gadus morhua 28.81 5.00e-45 173.00
IUUC-Ggr-040115 Gaeumannomyces graminis 32.14 3.00e-55 207.00
IUUC-Gac-041650 Gasterosteus aculeatus 30.06 2.00e-47 181.00
IUUC-Gma-043697 Glycine max 29.32 8.00e-43 166.00
IUUC-Ggo-044707 Gorilla gorilla 28.00 5.00e-39 153.00
IUUC-Hsa-046041 Homo sapiens 29.32 3.00e-49 187.00
IUUC-Hvu-047816 Hordeum vulgare 28.97 9.00e-36 142.00
IUUC-Itr-048945 Ictidomys tridecemlineatus 32.40 8.00e-38 148.00
IUUC-Lch-050419 Latimeria chalumnae 32.13 2.00e-51 194.00
IUUC-Lpe-051593 Leersia perrieri 28.79 2.00e-42 164.00
IUUC-Loc-052930 Lepisosteus oculatus 30.49 9.00e-50 189.00
IUUC-Lma-053256 Leptosphaeria maculans 31.56 5.00e-61 226.00
IUUC-Laf-053555 Loxodonta africana 29.60 3.00e-48 184.00
IUUC-Mcc-055630 Macaca mulatta 29.32 3.00e-49 187.00
IUUC-Meu-056579 Macropus eugenii 22.46 2.00e-12 65.50
IUUC-Mor-057078 Magnaporthe oryzae 32.24 9.00e-55 206.00
IUUC-Mpo-057607 Magnaporthe poae 29.30 8.00e-43 166.00
IUUC-Mtr-058644 Medicago truncatula 29.65 2.00e-45 174.00
IUUC-Mla-059120 Melampsora laricipopulina 29.16 2.00e-56 211.00
IUUC-Mvi-060429 Microbotryum violaceum 31.16 5.00e-41 160.00
IUUC-Mmr-061313 Microcebus murinus 29.32 4.00e-49 187.00
IUUC-Mdo-062801 Monodelphis domestica 29.32 4.00e-49 187.00
IUUC-Mmu-064424 Mus musculus 29.54 1.00e-50 192.00
IUUC-Mac-065115 Musa acuminata 27.85 3.00e-39 154.00
IUUC-Mpu-065980 Mustela putorius furo 27.00 1.00e-33 135.00
IUUC-Mlu-067007 Myotis lucifugus 29.32 3.00e-49 187.00
IUUC-Nfi-068274 Neosartorya fischeri 29.03 3.00e-47 181.00
IUUC-Ncr-068829 Neurospora crassa 32.24 1.00e-57 215.00
IUUC-Nle-069171 Nomascus leucogenys 29.32 6.00e-49 186.00
IUUC-Opr-070494 Ochotona princeps 26.32 1.00e-31 129.00
IUUC-Ont-072290 Oreochromis niloticus 30.34 3.00e-49 187.00
IUUC-Oan-073099 Ornithorhynchus anatinus 29.32 6.00e-49 186.00
IUUC-Ocu-074642 Oryctolagus cuniculus 29.32 4.00e-49 187.00
IUUC-Oba-075886 Oryza barthii 28.57 4.00e-43 167.00
IUUC-Obr-076220 Oryza brachyantha 28.91 1.00e-43 169.00
IUUC-Ogl-077682 Oryza glaberrima 28.79 2.00e-43 168.00
IUUC-Ogu-078492 Oryza glumaepatula 29.12 6.00e-43 166.00
IUUC-Oin-079956 Oryza indica 28.57 5.00e-43 166.00
IUUC-Olo-080239 Oryza longistaminata 27.27 3.00e-29 122.00
IUUC-Ome-081573 Oryza meridionalis 28.51 7.00e-44 169.00
IUUC-Oni-082975 Oryza nivara 28.57 5.00e-43 166.00
IUUC-Opu-083724 Oryza punctata 28.31 9.00e-44 169.00
IUUC-Oru-084566 Oryza rufipogon 28.79 2.00e-43 168.00
IUUC-Osa-086008 Oryza sativa 28.79 1.00e-43 168.00
IUUC-Ola-086967 Oryzias latipes 30.77 3.00e-50 190.00
IUUC-Olu-087614 Ostreococcus lucimarinus 28.03 6.00e-41 159.00
IUUC-Oga-088047 Otolemur garnettii 28.69 8.00e-31 125.00
IUUC-Oar-089393 Ovis aries 29.32 3.00e-49 187.00
IUUC-Ptr-090561 Pan troglodytes 29.32 3.00e-49 187.00
IUUC-Pan-091812 Papio anubis 29.32 3.00e-49 187.00
IUUC-Psi-093507 Pelodiscus sinensis 23.03 2.00e-14 70.90
IUUC-Pno-095104 Phaeosphaeria nodorum 31.91 2.00e-61 228.00
IUUC-Ppa-095995 Physcomitrella patens 27.78 2.00e-43 168.00
IUUC-Pfo-096754 Poecilia formosa 29.96 2.00e-48 184.00
IUUC-Pab-098053 Pongo abelii 29.32 3.00e-49 187.00
IUUC-Pop-099158 Populus trichocarpa 28.63 3.00e-40 157.00
IUUC-Pca-100407 Procavia capensis 25.75 9.00e-31 126.00
IUUC-Ppe-101699 Prunus persica 29.06 1.00e-40 159.00
IUUC-Pva-103159 Pteropus vampyrus 30.54 2.00e-48 185.00
IUUC-Pgr-103433 Puccinia graminis 32.19 6.00e-61 226.00
IUUC-Ptt-103701 Puccinia triticina 28.93 1.00e-51 195.00
IUUC-Pte-104281 Pyrenophora teres 32.08 3.00e-62 230.00
IUUC-Pyt-104714 Pyrenophora triticirepentis 32.63 3.00e-63 233.00
IUUC-Rno-105531 Rattus norvegicus 29.75 3.00e-51 194.00
IUUC-Sha-107093 Sarcophilus harrisii 29.32 4.00e-49 187.00
IUUC-Sja-108004 Schizosaccharomyces japonicus 31.59 3.00e-62 230.00
IUUC-Spo-108018 Schizosaccharomyces pombe 31.72 4.00e-63 233.00
IUUC-Ssl-108460 Sclerotinia sclerotiorum 31.80 5.00e-52 196.00
IUUC-Smo-108892 Selaginella moellendorffii 28.38 3.00e-42 164.00
IUUC-Sit-110782 Setaria italica 27.91 5.00e-42 163.00
IUUC-Sly-111308 Solanum lycopersicum 29.89 1.00e-47 182.00
IUUC-Stu-112447 Solanum tuberosum 28.82 5.00e-47 180.00
IUUC-Sar-113352 Sorex araneus 27.04 3.00e-27 114.00
IUUC-Sbi-114806 Sorghum bicolor 28.48 5.00e-43 167.00
IUUC-Sre-115059 Sporisorium reilianum 29.54 4.00e-51 194.00
IUUC-Ssc-115677 Sus scrofa 31.10 4.00e-38 150.00
IUUC-Tru-118478 Takifugu rubripes 29.98 1.00e-47 182.00
IUUC-Tsy-119082 Tarsius syrichta 35.48 3.00e-19 87.40
IUUC-Tni-120419 Tetraodon nigroviridis 29.36 2.00e-44 171.00
IUUC-Tca-121294 Theobroma cacao 28.99 6.00e-49 186.00
IUUC-Tre-121962 Trichoderma reesei 32.82 3.00e-57 214.00
IUUC-Tvi-122280 Trichoderma virens 32.46 3.00e-60 224.00
IUUC-Tae-124442 Triticum aestivum 29.03 4.00e-43 167.00
IUUC-Tur-126551 Triticum urartu 29.03 5.00e-43 166.00
IUUC-Tme-126959 Tuber melanosporum 31.43 1.00e-60 225.00
IUUC-Tbe-127737 Tupaia belangeri 29.03 7.00e-47 179.00
IUUC-Ttr-129211 Tursiops truncatus 39.90 1.00e-35 142.00
IUUC-Uma-129591 Ustilago maydis 28.44 1.00e-51 196.00
IUUC-Vda-129674 Verticillium dahliae 32.31 4.00e-56 210.00
IUUC-Vpa-130793 Vicugna pacos 39.67 2.00e-33 135.00
IUUC-Xtr-132430 Xenopus tropicalis 30.93 2.00e-48 184.00
IUUC-Xma-133515 Xiphophorus maculatus 29.54 1.00e-48 185.00
IUUC-Yli-134488 Yarrowia lipolytica 33.33 1.00e-60 224.00
IUUC-Zma-134748 Zea mays 28.69 9.00e-44 169.00
Created Date 25-Jun-2017

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