iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090502

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03143919

Gene Name

HUWE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000021930.5	ENSPTRT00000049267.4	ENSPTRP00000047397.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.70e-08	32.9	823	860

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           ++++l+ql++MGF+re+a +aL++   + e A+eyLl++
   Q: 823  NQQQLQQLMDMGFTREHAMEALLN-TSTMEQATEYLLTH 860
           89**********************.7***********98 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

PGVQCIPQRA ALLKSMLNFL KKAIQDPAFS DGIRHVMDGS LPTSLKHIIS NAEYYGPSLF 60
LLATEVVTVF VFQEPSLLSS LQDNGLTDVM LHALLIKDVP ATREVLGSLP NVFSALCLNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTTTGAGC TGAGCCGAAG CGGGGAGGCT TTCGACTGAG GGCTAGCGAG GGGAGCAGGG 60
CTGGAGCAGG GCTGGAGCAG GGCTGAAGCA GGGCTGAAGC AGGGCCGCGG ACCCCGCACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR025527--DUF4414
IPR010314--E3_Ub_ligase_DUF913
IPR015940--UBA
IPR009060--UBA-like
IPR004170--WWE-dom

PROSITE

PS50030--UBA
PS50918--WWE

Pfam

PF14377--DUF4414
PF06025--DUF913
PF00627--UBA
PF02825--WWE

SMART

SM00165--UBA

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0003723--F:RNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006284--P:base-excision repair
GO:0016574--P:histone ubiquitination
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001684	Ailuropoda melanoleuca	99.22	0.00e+00	3428.00
IUUC-Aca-005263	Anolis carolinensis	92.60	0.00e+00	3133.00
IUUC-Ame-011067	Astyanax mexicanus	80.00	0.00e+00	2791.00
IUUC-Bta-012813	Bos taurus	98.85	0.00e+00	3460.00
IUUC-Bol-015228	Brassica oleracea	24.34	4.00e-11	65.10
IUUC-Cja-018741	Callithrix jacchus	99.42	0.00e+00	3449.00
IUUC-Cfa-020083	Canis familiaris	99.22	0.00e+00	3440.00
IUUC-Cpo-021923	Cavia porcellus	97.86	0.00e+00	3392.00
IUUC-Csa-023853	Chlorocebus sabaeus	99.63	0.00e+00	3449.00
IUUC-Cho-024718	Choloepus hoffmanni	97.57	0.00e+00	677.00
IUUC-Cin-025627	Ciona intestinalis	39.50	0.00e+00	1322.00
IUUC-Csv-025824	Ciona savignyi	43.99	0.00e+00	891.00
IUUC-Dre-028525	Danio rerio	81.49	0.00e+00	2779.00
IUUC-Dno-029680	Dasypus novemcinctus	97.96	0.00e+00	3367.00
IUUC-Dor-030902	Dipodomys ordii	96.20	0.00e+00	1216.00
IUUC-Dme-032122	Drosophila melanogaster	39.62	9.00e-107	384.00
IUUC-Ete-032690	Echinops telfairi	83.94	0.00e+00	1131.00
IUUC-Eca-033915	Equus caballus	98.54	0.00e+00	3434.00
IUUC-Eeu-034963	Erinaceus europaeus	91.63	0.00e+00	1967.00
IUUC-Fca-035824	Felis catus	99.16	0.00e+00	3432.00
IUUC-Gmo-039073	Gadus morhua	81.11	0.00e+00	2759.00
IUUC-Gac-042430	Gasterosteus aculeatus	81.46	0.00e+00	2815.00
IUUC-Ggo-044785	Gorilla gorilla	99.95	0.00e+00	3423.00
IUUC-Hsa-046879	Homo sapiens	100.00	0.00e+00	3425.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	97.06	0.00e+00	1118.00
IUUC-Lch-050252	Latimeria chalumnae	88.16	0.00e+00	2962.00
IUUC-Loc-052472	Lepisosteus oculatus	83.32	0.00e+00	2828.00
IUUC-Laf-054154	Loxodonta africana	98.12	0.00e+00	3398.00
IUUC-Mcc-055085	Macaca mulatta	99.74	0.00e+00	3447.00
IUUC-Meu-056727	Macropus eugenii	92.06	0.00e+00	1851.00
IUUC-Mmr-060820	Microcebus murinus	98.96	0.00e+00	3387.00
IUUC-Mdo-062930	Monodelphis domestica	92.95	0.00e+00	3199.00
IUUC-Mmu-063601	Mus musculus	98.38	0.00e+00	3289.00
IUUC-Mpu-066653	Mustela putorius furo	96.76	0.00e+00	3304.00
IUUC-Mlu-067418	Myotis lucifugus	98.01	0.00e+00	3471.00
IUUC-Nle-069418	Nomascus leucogenys	99.48	0.00e+00	3388.00
IUUC-Opr-070187	Ochotona princeps	98.58	0.00e+00	681.00
IUUC-Ont-071300	Oreochromis niloticus	81.73	0.00e+00	2786.00
IUUC-Oan-073046	Ornithorhynchus anatinus	88.71	0.00e+00	4439.00
IUUC-Ocu-074178	Oryctolagus cuniculus	98.54	0.00e+00	3460.00
IUUC-Ogl-077590	Oryza glaberrima	25.00	8.00e-16	79.70
IUUC-Osa-086016	Oryza sativa	25.00	7.00e-16	80.10
IUUC-Ola-087437	Oryzias latipes	85.00	0.00e+00	1898.00
IUUC-Olu-087645	Ostreococcus lucimarinus	21.04	2.00e-10	63.20
IUUC-Oga-088903	Otolemur garnettii	99.01	0.00e+00	3395.00
IUUC-Oar-090210	Ovis aries	98.95	0.00e+00	3431.00
IUUC-Pan-092368	Papio anubis	99.69	0.00e+00	3449.00
IUUC-Pma-094246	Petromyzon marinus	74.50	0.00e+00	1294.00
IUUC-Pfo-096232	Poecilia formosa	79.72	0.00e+00	2771.00
IUUC-Pab-098583	Pongo abelii	99.95	0.00e+00	3420.00
IUUC-Pca-100310	Procavia capensis	94.47	0.00e+00	1310.00
IUUC-Pva-102116	Pteropus vampyrus	98.80	0.00e+00	3472.00
IUUC-Rno-105889	Rattus norvegicus	88.52	0.00e+00	2889.00
IUUC-Sha-106961	Sarcophilus harrisii	90.90	0.00e+00	3137.00
IUUC-Sar-113291	Sorex araneus	93.28	0.00e+00	2753.00
IUUC-Sre-115094	Sporisorium reilianum	29.04	2.00e-32	136.00
IUUC-Ssc-115754	Sus scrofa	99.42	0.00e+00	3439.00
IUUC-Tru-118570	Takifugu rubripes	81.07	0.00e+00	2841.00
IUUC-Tsy-119159	Tarsius syrichta	98.79	0.00e+00	2040.00
IUUC-Tni-120836	Tetraodon nigroviridis	77.63	0.00e+00	2008.00
IUUC-Tae-123539	Triticum aestivum	26.28	1.00e-13	72.40
IUUC-Tbe-127506	Tupaia belangeri	96.15	0.00e+00	1506.00
IUUC-Ttr-129253	Tursiops truncatus	91.48	0.00e+00	2206.00
IUUC-Uma-129331	Ustilago maydis	30.79	4.00e-32	135.00
IUUC-Vpa-130708	Vicugna pacos	97.92	0.00e+00	2920.00
IUUC-Xtr-132123	Xenopus tropicalis	83.51	0.00e+00	4099.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence