iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000008304.1	ENSPSIT00000009158.1	ENSPSIP00000009112.1
ENSPSIG00000008304.1	ENSPSIT00000009167.1	ENSPSIP00000009121.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.70e-09	36.0	37	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 37   CPICLDRFDNVAYLDRCLHRFCFRCVQEW------SKNKAECPLCK 76
           **********888899*************......**********7 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MISSSEEFTV DSSFSPKAGT SKLHQTVPTD TSPDSKCPIC LDRFDNVAYL DRCLHRFCFR 60
CVQEWSKNKA ECPLCKQPFH SIFHSVRAED DFKEYVLRPL QNGSFASPDG RRFRYRTTLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACATGATA TCATCAAGTG AGGAGTTTAC AGTGGATAGC AGTTTTTCAC CGAAAGCTGG 60
CACAAGCAAG CTGCATCAGA CAGTGCCAAC AGATACATCT CCAGATTCTA AATGTCCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	38.24	2.00e-09	55.80
IUUC-Aml-002240	Ailuropoda melanoleuca	74.25	0.00e+00	647.00
IUUC-Atr-002964	Amborella trichopoda	31.91	1.00e-10	60.10
IUUC-Apl-003666	Anas platyrhynchos	65.19	6.00e-170	590.00
IUUC-Aca-005305	Anolis carolinensis	68.02	1.00e-175	610.00
IUUC-Aly-005926	Arabidopsis lyrata	34.04	9.00e-11	60.50
IUUC-Ath-007299	Arabidopsis thaliana	42.37	4.00e-10	58.20
IUUC-Ame-011109	Astyanax mexicanus	54.50	4.00e-116	412.00
IUUC-Bta-012637	Bos taurus	74.71	0.00e+00	652.00
IUUC-Bdi-014270	Brachypodium distachyon	40.54	1.00e-11	63.20
IUUC-Bol-015147	Brassica oleracea	43.94	2.00e-09	57.80
IUUC-Bra-016799	Brassica rapa	34.69	4.00e-09	55.80
IUUC-Cja-019105	Callithrix jacchus	68.55	0.00e+00	681.00
IUUC-Cfa-021203	Canis familiaris	69.84	0.00e+00	647.00
IUUC-Cpo-022335	Cavia porcellus	66.04	2.00e-179	622.00
IUUC-Csa-023870	Chlorocebus sabaeus	68.55	0.00e+00	675.00
IUUC-Cho-024870	Choloepus hoffmanni	71.55	0.00e+00	645.00
IUUC-Dre-027535	Danio rerio	51.19	3.00e-123	436.00
IUUC-Dno-028963	Dasypus novemcinctus	75.58	0.00e+00	649.00
IUUC-Dor-030239	Dipodomys ordii	68.08	2.00e-179	622.00
IUUC-Dme-031941	Drosophila melanogaster	32.88	6.00e-39	156.00
IUUC-Ete-032300	Echinops telfairi	58.85	0.00e+00	714.00
IUUC-Eca-033690	Equus caballus	68.74	0.00e+00	657.00
IUUC-Eeu-035257	Erinaceus europaeus	73.55	0.00e+00	628.00
IUUC-Fca-036383	Felis catus	68.17	0.00e+00	643.00
IUUC-Fal-037209	Ficedula albicollis	70.00	0.00e+00	638.00
IUUC-Gmo-039416	Gadus morhua	51.79	1.00e-115	409.00
IUUC-Gga-041267	Gallus gallus	82.38	0.00e+00	709.00
IUUC-Gac-042227	Gasterosteus aculeatus	53.18	5.00e-125	440.00
IUUC-Gma-043386	Glycine max	35.42	6.00e-12	64.30
IUUC-Ggo-044445	Gorilla gorilla	67.60	0.00e+00	676.00
IUUC-Hsa-045844	Homo sapiens	67.79	0.00e+00	677.00
IUUC-Hvu-047531	Hordeum vulgare	48.00	2.00e-10	56.60
IUUC-Itr-048818	Ictidomys tridecemlineatus	70.88	0.00e+00	658.00
IUUC-Lch-050031	Latimeria chalumnae	71.49	0.00e+00	635.00
IUUC-Lpe-051274	Leersia perrieri	39.62	8.00e-09	53.90
IUUC-Loc-052944	Lepisosteus oculatus	61.13	2.00e-152	533.00
IUUC-Laf-053820	Loxodonta africana	73.47	0.00e+00	652.00
IUUC-Mcc-054800	Macaca mulatta	68.55	0.00e+00	676.00
IUUC-Meu-056806	Macropus eugenii	74.88	2.00e-180	625.00
IUUC-Mtr-058378	Medicago truncatula	35.58	9.00e-14	70.10
IUUC-Mmr-061481	Microcebus murinus	76.05	0.00e+00	660.00
IUUC-Mdo-062219	Monodelphis domestica	73.53	8.00e-109	387.00
IUUC-Mmu-064138	Mus musculus	68.68	6.00e-173	601.00
IUUC-Mac-064635	Musa acuminata	33.67	3.00e-11	60.50
IUUC-Mlu-067088	Myotis lucifugus	69.84	0.00e+00	644.00
IUUC-Nle-069862	Nomascus leucogenys	68.55	0.00e+00	674.00
IUUC-Opr-071076	Ochotona princeps	74.01	5.00e-177	614.00
IUUC-Ont-072225	Oreochromis niloticus	52.29	9.00e-119	421.00
IUUC-Oan-073069	Ornithorhynchus anatinus	66.52	2.00e-164	572.00
IUUC-Ocu-074826	Oryctolagus cuniculus	74.83	0.00e+00	661.00
IUUC-Oba-075429	Oryza barthii	39.13	1.00e-10	60.10
IUUC-Obr-076084	Oryza brachyantha	37.68	4.00e-10	58.20
IUUC-Ogl-077444	Oryza glaberrima	39.13	1.00e-10	59.70
IUUC-Ogu-078603	Oryza glumaepatula	39.13	1.00e-10	60.10
IUUC-Oin-079777	Oryza indica	39.13	1.00e-10	59.30
IUUC-Oni-082396	Oryza nivara	39.13	1.00e-10	60.10
IUUC-Opu-083698	Oryza punctata	38.03	8.00e-10	57.40
IUUC-Oru-084305	Oryza rufipogon	39.13	2.00e-10	59.70
IUUC-Ola-087377	Oryzias latipes	55.02	7.00e-115	407.00
IUUC-Oga-088059	Otolemur garnettii	73.07	0.00e+00	655.00
IUUC-Oar-089592	Ovis aries	75.17	0.00e+00	651.00
IUUC-Ptr-091233	Pan troglodytes	67.80	0.00e+00	677.00
IUUC-Pan-092743	Papio anubis	68.55	0.00e+00	676.00
IUUC-Ppa-095668	Physcomitrella patens	26.42	2.00e-20	93.60
IUUC-Pfo-096706	Poecilia formosa	53.78	7.00e-111	394.00
IUUC-Pca-100967	Procavia capensis	71.01	2.00e-170	592.00
IUUC-Pva-102982	Pteropus vampyrus	68.36	0.00e+00	649.00
IUUC-Rno-105730	Rattus norvegicus	73.07	6.00e-168	584.00
IUUC-Sha-106588	Sarcophilus harrisii	73.52	9.00e-180	624.00
IUUC-Smo-109039	Selaginella moellendorffii	25.16	5.00e-16	78.60
IUUC-Sar-113622	Sorex araneus	65.37	2.00e-114	407.00
IUUC-Sre-115041	Sporisorium reilianum	40.32	4.00e-08	51.60
IUUC-Ssc-115244	Sus scrofa	70.24	5.00e-178	618.00
IUUC-Tgu-117180	Taeniopygia guttata	69.29	0.00e+00	659.00
IUUC-Tru-118393	Takifugu rubripes	55.03	1.00e-126	446.00
IUUC-Tsy-119408	Tarsius syrichta	68.18	0.00e+00	654.00
IUUC-Tni-120664	Tetraodon nigroviridis	55.78	2.00e-122	433.00
IUUC-Tca-121712	Theobroma cacao	27.13	5.00e-18	84.70
IUUC-Tae-122787	Triticum aestivum	40.00	1.00e-10	60.10
IUUC-Tbe-127301	Tupaia belangeri	73.59	9.00e-167	580.00
IUUC-Ttr-128204	Tursiops truncatus	70.78	0.00e+00	656.00
IUUC-Uma-129420	Ustilago maydis	44.29	1.00e-09	57.00
IUUC-Vpa-130297	Vicugna pacos	69.81	0.00e+00	662.00
IUUC-Xtr-132845	Xenopus tropicalis	72.44	0.00e+00	674.00
IUUC-Xma-133439	Xiphophorus maculatus	52.52	1.00e-114	407.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence