PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus AGO3 TNRC6C 24778252,19383768,19470757 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G GP G G CNOT1 TNRC6C 21984185,23463101,21981923,21984184 biogrid,intact,dip exp G G G G G G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TNRC6C CNOT6 21981923,21984184 biogrid,intact exp G G G G G G G G GP G G G G G G P G G G G G G G GP GP GP G G RQCD1 TNRC6C 21984185 dip exp G G G G G G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TNRC6C CNOT8 21981923,21984184 biogrid,intact exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G PABPC1 TNRC6C 20098421,21063388,21981923,21984184,23340509,20181956,19716330 biogrid,mint,intact,dip exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TNRC6C AGO4 19383768 biogrid,intact exp G G G G GP G G G G G G G G G G P G G GP G G G G GP G GP G G PABPC4 TNRC6C 21984184 biogrid exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G CNOT6L TNRC6C 21984185,21981923 biogrid,intact,dip exp G G G G G G G G GP G G G G G G P G G G G G G G GP GP GP G G NAPRT TNRC6C 26344197 biogrid exp G G G G G G G G GP G G G G G P G G P G G GP G GP GP G SCLT1 TNRC6C 26638075 biogrid,intact exp G G G G GP G G G P G G G GP G P G G GP G P G GP GP GP GP TNRC6C CNOT2 21984185,21981923 biogrid,intact,dip exp G G G G G G G G G G G G G G G G G G G G G G G G G G G PTBP3 TNRC6C 22575643 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G CNOT10 TNRC6C 21984185,21981923,21984184 biogrid,intact,dip exp G G G G GP G G G GP G G G G GP G P G G P G P G G G GP GP GP GP G CUL3 TNRC6C 21145461 biogrid exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G CEP44 TNRC6C 26638075 biogrid,intact exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G XPO1 TNRC6C 26673895 biogrid exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TNRC6C CNOT7 21984185,21981923 biogrid,intact,dip exp G G G G G G G G G G G G G G G G G G G G G G G G G G G ODF2 TNRC6C 26638075 biogrid,intact exp P GP EIF4G1 TNRC6C 19716330 intact exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G HNRNPUL2 TNRC6C 24778252 biogrid exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP G GP GP G AURKA TNRC6C 26186194 biogrid exp G GP G G G G GP G P G G G G GP GNB2L1 TNRC6C 26186194 biogrid exp P P P P P P P P P P PAN3 TNRC6C 21981923,21984184 biogrid,intact exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G MAPK6 TNRC6C 20936779 i2d exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G CNOT3 TNRC6C 21984185,21981923,21984184 biogrid,intact,dip exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TNRC6C NR2E1 26186194 biogrid exp G G G P G P P CAND1 TNRC6C 21145461 biogrid exp G G G G G G G G GP G G G G G G P G G G G G G G GP G G GP G CNTROB TNRC6C 26638075 biogrid,intact exp G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TNRC6C AGO1 24778252,26344197,19383768,19470757 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G PAN2 TNRC6C 21984185,21981923,21984184 biogrid,intact,dip exp G G G G G G G G G G G G G G G G G G G G G G G G G G G TNRC6C SSX2IP 26638075 biogrid,intact exp G G G G G G G GP G G G G G P G G GP G P G G G GP GP GP G TNRC6C AGO2 24778252,19838187,19383768,21981923,19470757 biogrid,intact,dip exp, ortho G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G CBLB TNRC6C 23023127 pred G G G G G G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G PARK2 TNRC6C 23023127 pred G G P G G G GP G G G P G G P G P G G GP P GP G TNRC6C AUP1 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G SOX6 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G GP G P G GP GP GP GP G SOX5 TNRC6C 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBQLN3 TNRC6C 23023127 pred G G G G G G GP G TNRC6C TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G NFATC2IP TNRC6C 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G DGCR8 TNRC6C 23023127 pred P P P P P P P P P P TDRD1 TNRC6C 23023127 pred P P P P P P P P P GP LATS1 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP G GP GP G RAPH1 TNRC6C 23023127 pred G G G P G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G UBQLNL TNRC6C 23023127 pred P P P P G P P P GP TNRC6C UBQLN2 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G DND1 TNRC6C 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G EP300 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TMUB1 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP G GP GP G TNRC6C CUEDC1 23023127 pred G G G G GP G G G GP G G G G GP G P G G P G P G G G GP GP GP P G SATB1 TNRC6C 23023127 pred G G G G G G G G G G G G G GP G G G G G G G G G G G GP G UBFD1 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TNRC6C UBQLN1 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G ASZ1 TNRC6C 23023127 pred P GP SUMO2 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G BAG6 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TNRC6C ITSN2 23023127 pred G G G G G G G G GP G G G G G G P G G GP G P G G G GP G GP GP G FAU TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G MDM4 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G UBASH3A TNRC6C 23023127 pred G G TNRC6C RHBDD3 23023127 pred G G G G GP G G G GP G G G G G G P G G GP G P G G G GP GP GP GP G UBXN2A TNRC6C 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TNRC6C FAF1 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TDRD3 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP UBL7 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G USP5 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TNRC6C NSFL1C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G HUWE1 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G NF2 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G UBTF TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G SUMO4 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G G G GP G P G G G G GP GP GP G UBXN11 TNRC6C 23023127 pred G G G G G G G G P G G G G G G P G G GP G P G G G GP G GP GP G TMUB2 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G UBC TNRC6C 23023127 pred AXIN1 TNRC6C 23023127 pred G G G GP G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G TNRC6C FBXO7 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP G GP GP G POU5F1 TNRC6C 23023127 pred P P P P P P P P P P TNRC6C DROSHA 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G CIDEA TNRC6C 23023127 pred G G G G G G G UBXN10 TNRC6C 23023127 pred G G G G GP G G G GP G G G G P G G GP G P G G G GP G GP GP G UBL4B TNRC6C 23023127 pred P P P P P P P P P P MIDN TNRC6C 23023127 pred G G G G GP G G G GP G G G G G G P G G G G P G G G GP G GP GP G TNRC6C TAB2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G NLRP13 TNRC6C 23023127 pred GP P P P P G P P P P PRKRA TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G UBXN2B TNRC6C 23023127 pred G G G G G G G G GP G G G G G G P G G G G G G G GP G GP GP G DCDC2B TNRC6C 23023127 pred G G G G G G P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9HCJ0 pull down 21984185 - C 5 Q9HCJ0 pull down 21984185 - C 4 Q9HCJ0 pull down 21984185 - C 6 Q9HCJ0 pull down 21984185 - C 3 Q9HCJ0 pull down 21984185 - C 3 Q9HCJ0 A0A024R9C1 molecular sieving 20098421 direct interaction X 2 Q9HCJ0 A0A024R9C1 x-ray crystallography 20098421 direct interaction X 2 Q9HCJ0 A0A024R9C1 pull down 20098421 direct interaction X 2 Q9HCJ0 A0A024R9C1 pull down 20098421 direct interaction X 2 Q9HCJ0 A0A024R9C1 pull down 20098421 direct interaction X 2 Q9HCJ0 A5YKK6 pull down 21984185 direct interaction X 2 Q9HCJ0 A5YKK6 pull down 21984185 direct interaction X 2 Q9HCJ0 A5YKK6 pull down 21984185 direct interaction X 2 Q9HCJ0 A5YKK6 pull down 21984185 direct interaction X 2 Q9HCJ0 A5YKK6 pull down 21984185 direct interaction X 2 Q9HCJ0 A5YKK6 pull down 21984185 direct interaction X 2 Q9HCJ0 A5YKK6 pull down 21984185 direct interaction X 2 Q9HCJ0 A5YKK6 anti tag coimmunoprecipitation 21984185 direct interaction X 2 Q9HCJ0 A5YKK6 pull down 21984185 direct interaction X 2 Q9HCJ0 A5YKK6 pull down 21984185 direct interaction X 2 Q60809 Q9HCJ0 pull down 21984185 physical association X 2 Q9UKV8 Q9HCJ0 anti tag coimmunoprecipitation 19838187 physical association X 2 A0A024RBD8 Q9HCJ0 pull down 21984185 physical association X 2 Q9HCJ0 pull down 21984185 - C 4 Q9HCJ0 pull down 21984185 - C 7 Q9HCJ0 anti tag coimmunoprecipitation 21984185 - C 6 Q9HCJ0 pull down 21984185 - C 6 Q9HCJ0 pull down 21984185 - C 6 Q9HCJ0 pull down 21984185 - C 6 Q9HCJ0 pull down 21984185 - C 8 Q9HCJ0 A0A024R4R3 pull down 21984185 physical association X 2 Q9HCJ0 A0A024R4R3 pull down 21984185 physical association X 2 Q9HCJ0 A0A024R4R3 anti tag coimmunoprecipitation 21984185 physical association X 2 Q9HCJ0 A0A024R4R3 pull down 21984185 physical association X 2 Q9HCJ0 A0A024R4R3 pull down 21984185 physical association X 2 Q9HCJ0 A0A024R4R3 pull down 21984185 physical association X 2 Q9HCJ0 A0A024R4R3 pull down 21984185 physical association X 2 Q9HCJ0 A0A024R4R3 pull down 21984185 physical association X 2 Q9HCJ0 A0A024R4R3 pull down 21984185 physical association X 2 Q8CJG0 Q9HCJ0 anti tag coimmunoprecipitation 19838187 physical association X 2 D5MQE1 Q9HCJ0 pull down 21984185 physical association X 2 D5MQE1 Q9HCJ0 pull down 21984185 physical association X 2 D5MQE1 Q9HCJ0 pull down 21984185 physical association X 2 D5MQE1 Q9HCJ0 pull down 21984185 physical association X 2 D5MQE1 Q9HCJ0 pull down 21984185 physical association X 2 Q9UIV1 Q9HCJ0 pull down 21984185 physical association X 2 Q9UIV1 Q9HCJ0 pull down 21984185 physical association X 2 Q9UIV1 Q9HCJ0 pull down 21984185 physical association X 2 Q9UIV1 Q9HCJ0 pull down 21984185 physical association X 2 Q9UIV1 Q9HCJ0 anti tag coimmunoprecipitation 21984185 physical association X 2 Q9UIV1 Q9HCJ0 pull down 21984185 physical association X 2 Q9UIV1 Q9HCJ0 pull down 21984185 physical association X 2 Q9UIV1 Q9HCJ0 pull down 21984185 physical association X 2 Q6ZQ08 Q9HCJ0 pull down 21984185 physical association X 2 Q9H9A5 Q9HCJ0 pull down 21984185 physical association X 2 Q9H9A5 Q9HCJ0 anti tag coimmunoprecipitation 21984185 physical association X 2 Q9H9A5 Q9HCJ0 pull down 21984185 physical association X 2 Q9H9A5 Q9HCJ0 pull down 21984185 physical association X 2 Q9H9A5 Q9HCJ0 pull down 21984185 physical association X 2 Q9H9A5 Q9HCJ0 pull down 21984185 physical association X 2 Q9H9A5 Q9HCJ0 pull down 21984185 physical association X 2 Q9H9A5 Q9HCJ0 pull down 21984185 physical association X 2 Q9H9A5 Q9HCJ0 pull down 21984185 physical association X 2 Q96LI5 Q9HCJ0 pull down 21984185 physical association X 2 Q96LI5 Q9HCJ0 anti tag coimmunoprecipitation 21984185 physical association X 2 Q96LI5 Q9HCJ0 pull down 21984185 physical association X 2 Q96LI5 Q9HCJ0 pull down 21984185 physical association X 2 Q96LI5 Q9HCJ0 pull down 21984185 physical association X 2 Q504Q3 Q9HCJ0 pull down 21984185 physical association X 2 Q504Q3 Q9HCJ0 pull down 21984185 physical association X 2 Q504Q3 Q9HCJ0 pull down 21984185 physical association X 2 Q504Q3 Q9HCJ0 pull down 21984185 physical association X 2 Q504Q3 Q9HCJ0 pull down 21984185 physical association X 2 Q504Q3 Q9HCJ0 pull down 21984185 physical association X 2 Q9HCJ0 anti tag coimmunoprecipitation 21981923 association C 3 Q9HCJ0 pull down 19716330 association C 3 Q9HCJ0 anti tag coimmunoprecipitation 23340509 association C 3 Q9HCJ0 A0A024R9C1 pull down 19716330 physical association X 2 Q9HCJ0 A0A024R9C1 anti tag coimmunoprecipitation 19716330 physical association X 2 Q9HCJ0 A0A024R9C1 pull down 19716330 physical association X 2 Q9HCJ0 A0A024R9C1 pull down 19716330 physical association X 2 Q9HCJ0 A0A024R9C1 x-ray crystallography 20181956 direct interaction X 2 Q9HCJ0 A0A024R9C1 nuclear magnetic resonance 20181956 direct interaction X 2 Q9HCJ0 A0A024R9C1 nuclear magnetic resonance 20181956 direct interaction X 2 Q9HCJ0 A0A024R9C1 isothermal titration calorimetry 20181956 direct interaction X 2 Q9HCJ0 A0A024R9C1 anti tag coimmunoprecipitation 21063388 physical association X 2 Q9HCJ0 A0A024R9C1 anti tag coimmunoprecipitation 21063388 physical association X 2 Q9HCJ0 A0A024R9C1 anti tag coimmunoprecipitation 21063388 physical association X 2 Q9HCJ0 A0A024R9C1 anti tag coimmunoprecipitation 21063388 physical association X 2 Q9HCJ0 A0A024R9C1 anti tag coimmunoprecipitation 21063388 physical association X 2 Q9HCJ0 P21187 anti tag coimmunoprecipitation 21063388 physical association X 2 Q9HCJ0 A5YKK6 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9HCJ0 Q58A45 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9HCJ0 Q58A45 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9HCJ0 A5YKK6 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9HCJ0 A0A024R9C1 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9HCJ0 A5YKK6 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9HCJ0 A5YKK6 anti tag coimmunoprecipitation 23463101 physical association X 2 Q9HCJ0 A5YKK6 anti tag coimmunoprecipitation 23463101 physical association X 2 Q9HCJ0 P21187 anti tag coimmunoprecipitation 23463101 physical association X 2 Q9HCJ0 P21187 anti tag coimmunoprecipitation 23463101 physical association X 2 Q9HCJ0 P21187 anti tag coimmunoprecipitation 23463101 physical association X 2 Q9HCJ0 P21187 anti tag coimmunoprecipitation 23463101 physical association X 2 Q9UKV8 Q9HCJ0 confocal microscopy 19383768 colocalization X 2 Q9UKV8 Q9HCJ0 anti tag coimmunoprecipitation 19383768 physical association X 2 Q9UKV8 Q9HCJ0 anti tag coimmunoprecipitation 21981923 physical association X 2 A0A024RBD8 Q9HCJ0 anti tag coimmunoprecipitation 21981923 physical association X 2 A0A024RBD8 Q9HCJ0 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9HCJ0 anti tag coimmunoprecipitation 21981923 association C 4 Q9HCJ0 anti tag coimmunoprecipitation 23340509 association C 4 Q9HCJ0 anti tag coimmunoprecipitation 21981923 association C 3 Q9HCJ0 Q9UL18 confocal microscopy 19383768 colocalization X 2 Q9HCJ0 Q9UL18 anti tag coimmunoprecipitation 19383768 physical association X 2 Q9HCJ0 Q9H9G7 anti tag coimmunoprecipitation 19383768 physical association X 2 Q9HCJ0 Q9H9G7 confocal microscopy 19383768 colocalization X 2 Q9HCJ0 Q9HCK5 anti tag coimmunoprecipitation 19383768 physical association X 2 Q9HCJ0 Q9HCK5 confocal microscopy 19383768 colocalization X 2 Q9HCJ0 Q9UFF9 anti tag coimmunoprecipitation 21981923 association X 2 Q9HCJ0 A0A024R4R3 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9HCJ0 Q9ULM6 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9HCJ0 Q9ULM6 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9UIV1 Q9HCJ0 anti tag coimmunoprecipitation 21981923 physical association X 2 Q9H9A5 Q9HCJ0 anti tag coimmunoprecipitation 21981923 physical association X 2 Q96LI5 Q9HCJ0 anti tag coimmunoprecipitation 21981923 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B TNRC6C CNOT2 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_115555|UniProt_115558|UniProt_115530 bait|bait|bait prey|prey|prey TNRC6C EIF2C4 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19383768 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(biogrid)|(intact) BIOGRID_218096|UniProt_98321|BIOGRID_218093|UniProt_98314 prey|neutral component|prey|prey bait|neutral component|bait|bait CNOT10 TNRC6C MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_115551 prey bait CNOT6L TNRC6C MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_115531 prey bait EIF2C3 TNRC6C MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19383768,19470757 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact)|(intact)|(biogrid)|(biogrid) BIOGRID_218090|UniProt_98317|UniProt_98318|BIOGRID_218099|BIOGRID_206992 bait|bait|neutral component|bait|bait prey|prey|neutral component|prey|prey CAND1 TNRC6C MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_206532 bait prey PAN3 TNRC6C MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (intact)|(intact)|(intact)|(intact) UniProt_115555|UniProt_115529|UniProt_115552|UniProt_115536 prey|prey|bait|prey bait|bait|prey|bait PABPC1 TNRC6C MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0114(x-ray crystallography)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0007(anti tag coimmunoprecipitation)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 19716330,20098421,20181956,21063388,21981923,23340509 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (intact)|(intact)|MI:0465(dip)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid)|(intact)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact) UniProt_126574|UniProt_174213|DIP_55193|UniProt_104256|UniProt_102184|UniProt_102183|UniProt_104254|UniProt_104255|UniProt_102182|UniProt_104252|BIOGRID_195445|BIOGRID_195444|UniProt_111542|UniProt_111543|BIOGRID_194834|UniProt_111544|UniProt_111545|UniProt_111546|BIOGRID_259586|UniProt_115554|UniProt_102179|UniProt_115526|UniProt_102180 prey|prey|-|neutral component|bait|prey|neutral component|neutral component|prey|neutral component|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey bait|bait|-|neutral component|prey|bait|neutral component|neutral component|bait|neutral component|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait CUL3 TNRC6C MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_202026 bait prey CNOT3 TNRC6C MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_115525 prey bait TNRC6C EIF2C2 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19383768,19470757,19838187,21981923 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact)|(intact)|MI:0465(dip)|(biogrid)|(biogrid)|(biogrid) UniProt_98316|UniProt_98319|UniProt_115528|DIP_54942|BIOGRID_218087|BIOGRID_218102|BIOGRID_206991 prey|neutral component|prey|-|prey|prey|prey bait|neutral component|bait|-|bait|bait|bait TNRC6C EIF2C1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19383768,19470757 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact)|(biogrid)|(biogrid) UniProt_98315|BIOGRID_218084|UniProt_98320|BIOGRID_218105|BIOGRID_206990 prey|prey|neutral component|prey|prey bait|bait|neutral component|bait|bait TNRC6C CNOT6 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_115556|UniProt_115520 bait|bait prey|prey TNRC6C CNOT7 MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_115534 bait prey TNRC6C CNOT8 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21981923 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association) (intact)|(intact) UniProt_115521|UniProt_115526 bait|bait prey|prey TNRC6C CNOT1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21981923,23463101 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_115555|UniProt_115523|UniProt_115557|UniProt_130119|UniProt_130117|UniProt_115553|UniProt_46817|UniProt_46815 bait|bait|bait|bait|bait|prey|bait|bait prey|prey|prey|prey|prey|bait|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality CNOT1 TNRC6C 21981923,21981923,23463101,21984185,21984185,21984184 0007,0004,0007,0096,0007,0004 LC AURKA TNRC6C 26186194 0004 HT CNOT3 TNRC6C 21981923,21984185,21981923,21984184,21984185 0007,0007,0004,0004,0096 LC PABPC1 TNRC6C 21063388,21063388,21981923,19716330,23340509,19716330,23340509,20098421,19716330,21981923,21984184,20098421,20098421 0007,0004,0007,0004,0007,0007,0004,0096,0096,0004,0004,0114,0071 LC RACK1 TNRC6C 26186194 0004 HT CUL3 TNRC6C 21145461 0004 HT PAN2 TNRC6C 21981923,21984184,21981923,21984185 0007,0004,0004,0096 LC PAN3 TNRC6C 21981923,21984184,21981923 0007,0004,0004 LC ODF2 TNRC6C 26638075,26638075 1314,1313 HT NAPRT TNRC6C 26344197 0401 HT CAND1 TNRC6C 21145461 0004 HT CNTROB TNRC6C 26638075,26638075 1314,1313 HT CNOT6L TNRC6C 21981923,21984185,21981923,21984185 0007,0007,0004,0096 LC SCLT1 TNRC6C 26638075,26638075 1314,1313 HT CEP44 TNRC6C 26638075,26638075 1314,1313 HT CNOT10 TNRC6C 21981923,21984185,21984184,21984185 0007,0007,0004,0096 LC AGO3 TNRC6C 19383768,19383768,24778252,19470757,19383768,19383768 0007,0004,0004,0004,0096,0663 LC TNRC6C CNOT2 21981923,21981923,21984185 0007,0004,0096 LC TNRC6C CNOT8 21981923,21984184,21981923 0007,0004,0004 LC TNRC6C CNOT7 21981923,21984185,21981923,21984185 0007,0007,0004,0096 LC TNRC6C AGO2 21981923,21981923,19383768,19383768,24778252,19470757,19383768,19383768,19838187 0007,0004,0007,0004,0004,0004,0096,0663,0007 LC TNRC6C AGO1 26344197,19383768,19383768,24778252,19470757,19383768,19383768 0401,0007,0004,0004,0004,0096,0663 HT,LC TNRC6C CNOT6 21981923,21984184,21981923 0007,0004,0004 LC TNRC6C SSX2IP 26638075,26638075 1314,1313 HT TNRC6C NR2E1 26186194 0004 HT AURKA TNRC6C 26186194 0004 HT RACK1 TNRC6C 26186194 0004 HT CUL3 TNRC6C 21145461 0004 HT ODF2 TNRC6C 26638075,26638075 1314,1313 HT NAPRT TNRC6C 26344197 0401 HT CAND1 TNRC6C 21145461 0004 HT CNTROB TNRC6C 26638075,26638075 1314,1313 HT SCLT1 TNRC6C 26638075,26638075 1314,1313 HT CEP44 TNRC6C 26638075,26638075 1314,1313 HT TNRC6C AGO1 26344197 0401 HT TNRC6C SSX2IP 26638075,26638075 1314,1313 HT TNRC6C NR2E1 26186194 0004 HT CNOT1 TNRC6C 21981923,21981923,23463101,21984185,21984185,21984184 0007,0004,0007,0096,0007,0004 LC CNOT3 TNRC6C 21981923,21984185,21981923,21984184,21984185 0007,0007,0004,0004,0096 LC PABPC1 TNRC6C 21063388,21063388,21981923,19716330,23340509,19716330,23340509,20098421,19716330,21981923,21984184,20098421,20098421 0007,0004,0007,0004,0007,0007,0004,0096,0096,0004,0004,0114,0071 LC PAN2 TNRC6C 21981923,21984184,21981923,21984185 0007,0004,0004,0096 LC PAN3 TNRC6C 21981923,21984184,21981923 0007,0004,0004 LC CNOT6L TNRC6C 21981923,21984185,21981923,21984185 0007,0007,0004,0096 LC CNOT10 TNRC6C 21981923,21984185,21984184,21984185 0007,0007,0004,0096 LC AGO3 TNRC6C 19383768,19383768,24778252,19470757,19383768,19383768 0007,0004,0004,0004,0096,0663 LC TNRC6C CNOT2 21981923,21981923,21984185 0007,0004,0096 LC TNRC6C CNOT8 21981923,21984184,21981923 0007,0004,0004 LC TNRC6C CNOT7 21981923,21984185,21981923,21984185 0007,0007,0004,0096 LC TNRC6C AGO2 21981923,21981923,19383768,19383768,24778252,19470757,19383768,19383768,19838187 0007,0004,0007,0004,0004,0004,0096,0663,0007 LC TNRC6C AGO1 19383768,19383768,24778252,19470757,19383768,19383768 0007,0004,0004,0004,0096,0663 LC TNRC6C CNOT6 21981923,21984184,21981923 0007,0004,0004 LC PABPC1 TNRC6C 20181956,20181956,20098421,20181956,20098421,20098421 0114,0065,0096,0077,0114,0071 LC NAPRT TNRC6C 26344197 0401 LC TNRC6C TNRC6C 20098421 0114 LC TNRC6C AGO1 26344197 0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9HCJ0 Q58A45 TNRC6C PAN3 0.507 21981923,21984184 Q9HCJ0 O14965 TNRC6C AURKA 0.126 26186194 Q9HCJ0 O14980 TNRC6C XPO1 0.126 26673895 Q9HCJ0 Q8CJG0 TNRC6C AGO2 0.376 19838187,23340509 Q9HCJ0 Q8N137 TNRC6C CNTROB 0.126 26638075 Q9HCJ0 O75175 TNRC6C CNOT3 0.21 21981923 Q9HCJ0 P29341 TNRC6C PABPC1 0.21 23340509 Q9HCJ0 Q1KMD3 TNRC6C HNRNPUL2 0.126 24778252 Q9HCJ0 Q504Q3 TNRC6C PAN2 0.21 21981923 Q9HCJ0 Q96LI5 TNRC6C CNOT6L 0.21 21981923 Q9HCJ0 Q9H9G7 TNRC6C AGO3 0.671 24778252,19383768,19470757 Q9NZN8 Q9HCJ0 CNOT2 TNRC6C 0.21 21981923 Q9UFF9 Q9HCJ0 CNOT8 TNRC6C 0.21 21981923 Q9UIV1 Q9HCJ0 CNOT7 TNRC6C 0.21 21981923 Q9ULM6 Q9HCJ0 CNOT6 TNRC6C 0.21 21981923 Q9Y466 Q9HCJ0 NR2E1 TNRC6C 0.126 26186194 Q9Y2D8 Q9HCJ0 SSX2IP TNRC6C 0.126 26638075 Q9HCJ0 Q6XQN6 TNRC6C NAPRT1 0.081 26344197 Q9HCJ0 Q6P5F9 TNRC6C XPO1 0.126 26673895 Q9HCJ0 Q86VP6 TNRC6C CAND1 0.126 21145461 Q9HCJ0 O95758 TNRC6C PTBP3 0.126 22575643 Q9UKV8 Q9HCJ0 AGO2 TNRC6C 0.794 21981923,24778252,19838187,19383768,19470757 Q9UL18 Q9HCJ0 AGO1 TNRC6C 0.697 24778252,26344197,19383768,19470757 Q9HCK5 Q9HCJ0 AGO4 TNRC6C 0.454 19383768 Q9HCJ0 Q9C0F1 TNRC6C CEP44 0.236 26638075 Q9HCJ0 A5YKK6 TNRC6C CNOT1 0.692 21981923,23463101,21984184 Q9HCJ0 Q5BJF6 TNRC6C ODF2 0.236 26638075 Q9HCJ0 P11940 TNRC6C PABPC1 0.992 19716330,21981923,20181956,21063388,23340509,20098421 Q9HCJ0 Q96NL6 TNRC6C SCLT1 0.126 26638075 Q9HCJ0 Q13618 TNRC6C CUL3 0.126 21145461 Q9HCJ0 P63244 TNRC6C GNB2L1 0.126 26186194 Q9HCJ0 P21187 TNRC6C PABP 0.507 23463101,21063388

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 CNOT1 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database AURKA TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database XPO1 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database CNOT3 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database PTBP3 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database PABPC1 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database NOVA1 TNRC6C MI:0362 inference MI:0461 interaction database RACK1 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database EIF4G1 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database PABPC4 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database CUL3 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database TOB2 TNRC6C MI:0362 inference MI:0461 interaction database TARBP2 TNRC6C MI:0362 inference MI:0461 interaction database HNRNPUL2 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database PABPC1L TNRC6C MI:0362 inference MI:0461 interaction database PAN2 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database PAN3 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database ODF2 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database PABPC1L2A TNRC6C MI:0362 inference MI:0461 interaction database TAOK1 TNRC6C MI:0362 inference MI:0461 interaction database CAND1 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database GSPT2 TNRC6C MI:0362 inference MI:0461 interaction database CNTROB TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database TNRC6A TNRC6C MI:0362 inference MI:0461 interaction database RQCD1 TNRC6C MI:0362 inference MI:0461 interaction database FUBP3 TNRC6C MI:0362 inference MI:0461 interaction database CNOT6L TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database SCLT1 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database CEP44 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database TAOK3 TNRC6C MI:0362 inference MI:0461 interaction database PABPC3 TNRC6C MI:0362 inference MI:0461 interaction database CNOT10 TNRC6C MI:0045 experimental interaction detection MI:0461 interaction database AGO3 TNRC6C MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database MOV10 TNRC6C MI:0362 inference MI:1106 pathways database TNRC6C AGO4 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TNRC6C CNOT2 MI:0045 experimental interaction detection MI:0461 interaction database TNRC6C CNOT8 MI:0045 experimental interaction detection MI:0461 interaction database TNRC6C CNOT7 MI:0045 experimental interaction detection MI:0461 interaction database TNRC6C AGO2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TNRC6C AGO1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TNRC6C TAOK2 MI:0362 inference MI:0461 interaction database TNRC6C CNOT6 MI:0045 experimental interaction detection MI:0461 interaction database TNRC6C NOVA2 MI:0362 inference MI:0461 interaction database TNRC6C TNRC6B MI:0362 inference MI:0461 interaction database TNRC6C DICER1 MI:0362 inference MI:0461 interaction database TNRC6C SSX2IP MI:0045 experimental interaction detection MI:0461 interaction database TNRC6C NR2E1 MI:0045 experimental interaction detection MI:0461 interaction database