PTM - CPLM Gene Name UniProt ID Type Position Code GRAP2; GADS; GRB2L; GRID O75791 Acetylation 106 K GRAP2; GADS; GRB2L; GRID O75791 Ubiquitination 48 K GRAP2; GADS; GRB2L; GRID O75791 Ubiquitination 112 K GRAP2; GADS; GRB2L; GRID O75791 Ubiquitination 127 K GRAP2; GADS; GRB2L; GRID O75791 Ubiquitination 121 K GRAP2; GADS; GRB2L; GRID O75791 Ubiquitination 36 K GRAP2; GADS; GRB2L; GRID O75791 Ubiquitination 57 K GRAP2; GADS; GRB2L; GRID O75791 Ubiquitination 141 K

PTM - dbPAF Gene Name UniProt ID Position Type Species GRAP2; GADS; GRB2L; GRID O75791 131 Y Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 164 S Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 181 S Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 187 S Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 192 T Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 207 Y Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 222 Y Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 236 S Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 246 T Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 250 S Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 262 T Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 324 Y Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 41 S Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 45 Y Homo sapiens(Human) GRAP2; GADS; GRB2L; GRID O75791 87 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O75791 K106-ac Acetylation EDDVQHFkVMRDNKG O75791 R233-m1 Methylation HHFHQERrGGsLDIN O75791 S41-p Phosphorylation WFKAELGsQEGyVPK O75791 Y45-p Phosphorylation ELGsQEGyVPKNFID O75791 Y131-p Phosphorylation SLNKLVDyYRTNSIS O75791 S159-p Phosphorylation DQGHRGNsLDRRsQG O75791 S164-p Phosphorylation GNsLDRRsQGGPHLS O75791 S181-p Phosphorylation VGEEIRPsMNRKLsD O75791 S187-p Phosphorylation PsMNRKLsDHPPtLP O75791 T192-p Phosphorylation KLsDHPPtLPLQQHQ O75791 Y207-p Phosphorylation HQPQPPQyAPAPQQL O75791 Y222-p Phosphorylation QQPPQQRyLQHHHFH O75791 S236-p Phosphorylation HQERrGGsLDINDGH O75791 T246-p Phosphorylation INDGHCGtGLGsEMN O75791 S250-p Phosphorylation HCGtGLGsEMNAALM O75791 T262-p Phosphorylation ALMHRRHtDPVQLQA O75791 Y324-p Phosphorylation LGLFPANyVAPMTR_

PTM - dbPTM UniProt ID Position Code Type Resources References O75791 45 Y Phosphorylation Swiss-Prot 1010711 15144186;19690332 O75791 106 K Acetylation Swiss-Prot 1010711 19608861 O75791 262 T Phosphorylation Swiss-Prot 1010711 12522270;18088087;19690332 O75791 262 T Phosphorylation PhosphoELM.10011 18088087;15144186;12522270 O75791 45 Y Phosphorylation PhosphoELM.10011 15144186 O75791 106 K Acetylation Phosphositeplus.1010730 19608861 O75791 236 S Phosphorylation Phosphositeplus.1010730 22115753 O75791 262 T Phosphorylation Phosphositeplus.1010730 12522270;14729942;15144186;15570572;18088087;19690332 O75791 222 Y Phosphorylation Phosphositeplus.1010730 19690332 O75791 45 Y Phosphorylation Phosphositeplus.1010730 14729942;15144186;15570572;16493040;19690332 O75791 106 K Acetylation HPRD 9.0 19608861 O75791 262 T Phosphorylation HPRD 9.0 12522270,15144186,18088087 O75791 45 Y Phosphorylation HPRD 9.0 15144186 O75791 262 T Phosphorylation SysPTM 1.1 15144186;18088087

PTM - HPRD Symbol Position Code Type References GRAP2 106 K Acetylation 19608861 GRAP2 262 T Phosphorylation 12522270,15144186,18088087 GRAP2 45 Y Phosphorylation 15144186

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O75791 262 T 18088087 HTP Phosphorylation O75791 262 T 15144186 HTP Phosphorylation O75791 262 T 12522270 HTP Phosphorylation O75791 45 Y 15144186 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs O75791 45 Phosphotyrosine 15144186;19690332 O75791 106 N6-acetyllysine 19608861 O75791 262 Phosphothreonine 12522270;15144186;18088087;23186163;24275569

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type GRAP2 IPI00026928 K 106 DDVQHFaKVMRDNK acetylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 9402 114799 - K Ubiquitination 24816145 9402 114799 - K Ubiquitination 19850743