Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 16 731220 731220 + IGR SNP C C T TCGA-KQ-A41R-01A-21D-A34U-08 TCGA-KQ-A41R-10G-01D-A34X-08 g.chr16:731220C>T BLCA 16 731257 731257 + IGR SNP C C T TCGA-FD-A62S-01A-11D-A30E-08 TCGA-FD-A62S-10A-01D-A30H-08 g.chr16:731257C>T BLCA 16 731323 731323 + IGR SNP G G C TCGA-C4-A0F6-01A-11D-A10S-08 TCGA-C4-A0F6-10A-01D-A10S-08 g.chr16:731323G>C BLCA 16 731803 731803 + 3'UTR SNP G G C TCGA-G2-A2EO-01A-11D-A17V-08 TCGA-G2-A2EO-11A-21D-A17V-08 g.chr16:731803G>C BLCA 16 732373 732373 + 3'UTR SNP C C T TCGA-C4-A0F6-01A-11D-A10S-08 TCGA-C4-A0F6-10A-01D-A10S-08 g.chr16:732373C>T BLCA 16 732417 732417 + 3'UTR SNP C C T TCGA-CF-A3MG-01A-11D-A20D-08 TCGA-CF-A3MG-10A-01D-A20D-08 g.chr16:732417C>T BRCA 16 731457 731457 + IGR SNP G G A TCGA-BH-A0B6-01A-11D-A19Y-09 TCGA-BH-A0B6-10A-01D-A19Y-09 g.chr16:731457G>A BRCA 16 731505 731507 + IGR DEL GAA GAA - TCGA-BH-A0HA-01A-11D-A12Q-09 TCGA-BH-A0HA-11A-31D-A12Q-09 g.chr16:731505_731507delGAA BRCA 16 731865 731865 + 3'UTR SNP C C T TCGA-AR-A24N-01A-11D-A167-09 TCGA-AR-A24N-10A-01D-A167-09 g.chr16:731865C>T BRCA 16 732065 732065 + 3'UTR SNP G G A TCGA-AC-A23H-01A-11D-A159-09 TCGA-AC-A23H-11A-12D-A17G-09 g.chr16:732065G>A BRCA 16 732207 732207 + 3'UTR SNP G G C TCGA-PE-A5DE-01A-11D-A27P-09 TCGA-PE-A5DE-10A-01D-A27P-09 g.chr16:732207G>C CESC 16 731466 731466 + IGR SNP G G A TCGA-EK-A2RA-01A-11D-A18J-09 TCGA-EK-A2RA-10A-01D-A18J-09 g.chr16:731466G>A COAD 16 731333 731333 + IGR SNP T T C TCGA-AD-5900-01A-11D-1650-10 TCGA-AD-5900-10A-01D-1650-10 g.chr16:731333T>C COAD 16 731503 731503 + IGR SNP G G A TCGA-AY-6197-01A-11D-1719-10 TCGA-AY-6197-10A-01D-1719-10 g.chr16:731503G>A COAD 16 731505 731507 + IGR DEL GAA GAA - TCGA-AD-6895-01A-11D-1924-10 TCGA-AD-6895-10A-01D-1924-10 g.chr16:731505_731507delGAA COAD 16 731539 731539 + IGR SNP C C T TCGA-D5-6540-01A-11D-1719-10 TCGA-D5-6540-10A-01D-1719-10 g.chr16:731539C>T COAD 16 732019 732019 + 3'UTR SNP G G T TCGA-CA-6716-01A-11D-1835-10 TCGA-CA-6716-10A-01D-1835-10 g.chr16:732019G>T COAD 16 732261 732261 + 3'UTR SNP G G C TCGA-DM-A28F-01A-11D-A16V-10 TCGA-DM-A28F-10A-01D-A16V-10 g.chr16:732261G>C COADREAD 16 731333 731333 + IGR SNP T T C TCGA-AD-5900-01A-11D-1650-10 TCGA-AD-5900-10A-01D-1650-10 g.chr16:731333T>C COADREAD 16 731503 731503 + IGR SNP G G A TCGA-AY-6197-01A-11D-1719-10 TCGA-AY-6197-10A-01D-1719-10 g.chr16:731503G>A COADREAD 16 731505 731507 + IGR DEL GAA GAA - TCGA-AD-6895-01A-11D-1924-10 TCGA-AD-6895-10A-01D-1924-10 g.chr16:731505_731507delGAA COADREAD 16 731539 731539 + IGR SNP C C T TCGA-D5-6540-01A-11D-1719-10 TCGA-D5-6540-10A-01D-1719-10 g.chr16:731539C>T COADREAD 16 732019 732019 + 3'UTR SNP G G T TCGA-CA-6716-01A-11D-1835-10 TCGA-CA-6716-10A-01D-1835-10 g.chr16:732019G>T COADREAD 16 732261 732261 + 3'UTR SNP G G C TCGA-DM-A28F-01A-11D-A16V-10 TCGA-DM-A28F-10A-01D-A16V-10 g.chr16:732261G>C GBM 16 731823 731823 + 3'UTR SNP G G T TCGA-32-1982-01A-01D-1494-08 TCGA-32-1982-10A-01D-1494-08 g.chr16:731823G>T GBMLGG 16 731823 731823 + 3'UTR SNP G G T TCGA-32-1982-01A-01D-1494-08 TCGA-32-1982-10A-01D-1494-08 g.chr16:731823G>T GBMLGG 16 732441 732441 + 3'UTR SNP G G T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr16:732441G>T HNSC 16 731286 731286 + IGR SNP C C T TCGA-CQ-5331-01A-02D-1870-08 TCGA-CQ-5331-10A-01D-1870-08 g.chr16:731286C>T HNSC 16 731314 731314 + IGR SNP G G A TCGA-CV-7568-01A-11D-2229-08 TCGA-CV-7568-10A-01D-2229-08 g.chr16:731314G>A HNSC 16 732421 732421 + 3'UTR SNP C C T TCGA-BA-4076-01A-01D-1434-08 TCGA-BA-4076-10A-01D-1434-08 g.chr16:732421C>T HNSC 16 732456 732456 + 3'UTR SNP C C T TCGA-CV-7252-01A-11D-2012-08 TCGA-CV-7252-10A-01D-2013-08 g.chr16:732456C>T KIPAN 16 732019 732019 + 3'UTR SNP G G T TCGA-IA-A40U-01A-11D-A25F-10 TCGA-IA-A40U-10A-01D-A25F-10 g.chr16:732019G>T KIRP 16 732019 732019 + 3'UTR SNP G G T TCGA-IA-A40U-01A-11D-A25F-10 TCGA-IA-A40U-10A-01D-A25F-10 g.chr16:732019G>T LGG 16 732441 732441 + 3'UTR SNP G G T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr16:732441G>T LIHC 16 731813 731813 + 3'UTR SNP G G A TCGA-2Y-A9H7-01A-11D-A38X-10 TCGA-2Y-A9H7-10A-01D-A38X-10 g.chr16:731813G>A LIHC 16 731861 731892 + 3'UTR DEL CCTGCATTGAGGCCAAGCACGTGAGGGTGCCC CCTGCATTGAGGCCAAGCACGTGAGGGTGCCC - TCGA-2Y-A9GS-01A-12D-A382-10 TCGA-2Y-A9GS-10A-01D-A385-10 g.chr16:731861_731892delCCTGCATTGAGGCCAAGCACGTGAGGGTGCCC LIHC 16 732214 732214 + 3'UTR SNP T T C TCGA-CC-5262-01A-01D-A12Z-10 TCGA-CC-5262-10B-01D-A12Z-10 g.chr16:732214T>C LUAD 16 731479 731479 + IGR SNP G G A TCGA-75-5126-01A-01D-1753-08 TCGA-75-5126-10A-01D-1753-08 g.chr16:731479G>A OV 16 731186 731186 + IGR SNP A A T TCGA-42-2587-01A-01D-1526-09 TCGA-42-2587-10A-01D-1526-09 g.chr16:731186A>T SKCM 16 731537 731537 + IGR SNP G G A TCGA-D3-A51N-06A-11D-A25O-08 TCGA-D3-A51N-10A-01D-A25O-08 g.chr16:731537G>A

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US 16 726418 726418 single base substitution C T upstream_gene_variant BLCA-US 16 726483 726483 single base substitution G A upstream_gene_variant BLCA-US 16 726497 726497 single base substitution G A upstream_gene_variant BLCA-US 16 731323 731323 single base substitution G C exon_variant BLCA-US 16 731323 731323 single base substitution G C missense_variant D111H 331G>C BLCA-US 16 731323 731323 single base substitution G C missense_variant D16H 46G>C BLCA-US 16 731323 731323 single base substitution G C missense_variant D39H 115G>C BLCA-US 16 731323 731323 single base substitution G C missense_variant D92H 274G>C BLCA-US 16 731323 731323 single base substitution G C upstream_gene_variant BLCA-US 16 731803 731803 single base substitution G C downstream_gene_variant BLCA-US 16 731803 731803 single base substitution G C exon_variant BLCA-US 16 731803 731803 single base substitution G C missense_variant E107Q 319G>C BLCA-US 16 731803 731803 single base substitution G C missense_variant E160Q 478G>C BLCA-US 16 731803 731803 single base substitution G C missense_variant E179Q 535G>C BLCA-US 16 731803 731803 single base substitution G C missense_variant E45Q 133G>C BLCA-US 16 731803 731803 single base substitution G C missense_variant E84Q 250G>C BLCA-US 16 731803 731803 single base substitution G C upstream_gene_variant BLCA-US 16 732373 732373 single base substitution C T 3_prime_UTR_variant BLCA-US 16 732373 732373 single base substitution C T downstream_gene_variant BLCA-US 16 732373 732373 single base substitution C T exon_variant BLCA-US 16 732373 732373 single base substitution C T missense_variant H119Y 355C>T BLCA-US 16 732373 732373 single base substitution C T missense_variant H194Y 580C>T BLCA-US 16 732373 732373 single base substitution C T missense_variant H266Y 796C>T BLCA-US 16 732373 732373 single base substitution C T upstream_gene_variant BLCA-US 16 732417 732417 single base substitution C T 3_prime_UTR_variant BLCA-US 16 732417 732417 single base substitution C T 5_prime_UTR_variant BLCA-US 16 732417 732417 single base substitution C T downstream_gene_variant BLCA-US 16 732417 732417 single base substitution C T exon_variant BLCA-US 16 732417 732417 single base substitution C T synonymous_variant L133L 399C>T BLCA-US 16 732417 732417 single base substitution C T synonymous_variant L208L 624C>T BLCA-US 16 732417 732417 single base substitution C T synonymous_variant L280L 840C>T BLCA-US 16 735419 735419 single base substitution G C downstream_gene_variant BLCA-US 16 735939 735939 single base substitution G C downstream_gene_variant BLCA-US 16 737292 737292 single base substitution C T downstream_gene_variant BRCA-EU 16 725586 725586 single base substitution G C upstream_gene_variant BRCA-EU 16 725593 725593 single base substitution G A upstream_gene_variant BRCA-EU 16 725931 725931 single base substitution C G upstream_gene_variant BRCA-EU 16 726544 726544 single base substitution G A upstream_gene_variant BRCA-EU 16 730296 730296 single base substitution C G 5_prime_UTR_variant BRCA-EU 16 730296 730296 single base substitution C G upstream_gene_variant BRCA-EU 16 730450 730450 single base substitution C A 5_prime_UTR_variant BRCA-EU 16 730450 730450 single base substitution C A exon_variant BRCA-EU 16 730450 730450 single base substitution C A upstream_gene_variant BRCA-EU 16 731058 731058 single base substitution T G 5_prime_UTR_premature_start_codon_gain_variant BRCA-EU 16 731058 731058 single base substitution T G exon_variant BRCA-EU 16 731058 731058 single base substitution T G intron_variant BRCA-EU 16 731058 731058 single base substitution T G splice_region_variant BRCA-EU 16 731058 731058 single base substitution T G upstream_gene_variant BRCA-EU 16 731557 731557 single base substitution G A downstream_gene_variant BRCA-EU 16 731557 731557 single base substitution G A exon_variant BRCA-EU 16 731557 731557 single base substitution G A missense_variant E141K 421G>A BRCA-EU 16 731557 731557 single base substitution G A missense_variant E160K 478G>A BRCA-EU 16 731557 731557 single base substitution G A missense_variant E26K 76G>A BRCA-EU 16 731557 731557 single base substitution G A missense_variant E65K 193G>A BRCA-EU 16 731557 731557 single base substitution G A missense_variant E88K 262G>A BRCA-EU 16 731557 731557 single base substitution G A upstream_gene_variant BRCA-EU 16 731803 731803 single base substitution G C downstream_gene_variant BRCA-EU 16 731803 731803 single base substitution G C exon_variant BRCA-EU 16 731803 731803 single base substitution G C missense_variant E107Q 319G>C BRCA-EU 16 731803 731803 single base substitution G C missense_variant E160Q 478G>C BRCA-EU 16 731803 731803 single base substitution G C missense_variant E179Q 535G>C BRCA-EU 16 731803 731803 single base substitution G C missense_variant E45Q 133G>C BRCA-EU 16 731803 731803 single base substitution G C missense_variant E84Q 250G>C BRCA-EU 16 731803 731803 single base substitution G C upstream_gene_variant BRCA-EU 16 732745 732745 single base substitution G A 3_prime_UTR_variant BRCA-EU 16 732745 732745 single base substitution G A downstream_gene_variant BRCA-EU 16 732745 732745 single base substitution G A intron_variant BRCA-EU 16 732921 732921 single base substitution C T downstream_gene_variant BRCA-EU 16 733290 733290 single base substitution C T downstream_gene_variant BRCA-EU 16 733359 733359 single base substitution C T downstream_gene_variant BRCA-EU 16 733554 733554 insertion of <=200bp - G downstream_gene_variant BRCA-EU 16 734453 734453 single base substitution C T downstream_gene_variant BRCA-EU 16 735647 735647 single base substitution C G downstream_gene_variant BRCA-FR 16 725931 725931 single base substitution C G upstream_gene_variant BRCA-FR 16 735647 735647 single base substitution C G downstream_gene_variant BRCA-US 16 730615 730615 deletion of <=200bp G - 5_prime_UTR_variant BRCA-US 16 730615 730615 deletion of <=200bp G - exon_variant BRCA-US 16 730615 730615 deletion of <=200bp G - frameshift_variant K30 BRCA-US 16 730615 730615 deletion of <=200bp G - upstream_gene_variant BRCA-US 16 731457 731457 single base substitution G A downstream_gene_variant BRCA-US 16 731457 731457 single base substitution G A exon_variant BRCA-US 16 731457 731457 single base substitution G A synonymous_variant E107E 321G>A BRCA-US 16 731457 731457 single base substitution G A synonymous_variant E126E 378G>A BRCA-US 16 731457 731457 single base substitution G A synonymous_variant E31E 93G>A BRCA-US 16 731457 731457 single base substitution G A synonymous_variant E54E 162G>A BRCA-US 16 731457 731457 single base substitution G A upstream_gene_variant BRCA-US 16 731505 731507 deletion of <=200bp GAA - downstream_gene_variant BRCA-US 16 731505 731507 deletion of <=200bp GAA - exon_variant BRCA-US 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK123A BRCA-US 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK142A BRCA-US 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK47A BRCA-US 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK70A BRCA-US 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK8A BRCA-US 16 731505 731507 deletion of <=200bp GAA - upstream_gene_variant BRCA-US 16 731865 731865 single base substitution C T downstream_gene_variant BRCA-US 16 731865 731865 single base substitution C T exon_variant BRCA-US 16 731865 731865 single base substitution C T synonymous_variant C104C 312C>T BRCA-US 16 731865 731865 single base substitution C T synonymous_variant C127C 381C>T BRCA-US 16 731865 731865 single base substitution C T synonymous_variant C180C 540C>T BRCA-US 16 731865 731865 single base substitution C T synonymous_variant C199C 597C>T BRCA-US 16 731865 731865 single base substitution C T synonymous_variant C65C 195C>T BRCA-US 16 731865 731865 single base substitution C T upstream_gene_variant BRCA-US 16 732065 732065 single base substitution G A downstream_gene_variant BRCA-US 16 732065 732065 single base substitution G A exon_variant BRCA-US 16 732065 732065 single base substitution G A missense_variant E125K 373G>A BRCA-US 16 732065 732065 single base substitution G A missense_variant E148K 442G>A BRCA-US 16 732065 732065 single base substitution G A missense_variant E201K 601G>A BRCA-US 16 732065 732065 single base substitution G A missense_variant E220K 658G>A BRCA-US 16 732065 732065 single base substitution G A missense_variant E73K 217G>A BRCA-US 16 732065 732065 single base substitution G A upstream_gene_variant BRCA-US 16 733406 733406 single base substitution C T downstream_gene_variant BRCA-US 16 735108 735108 insertion of <=200bp - A downstream_gene_variant BRCA-US 16 735944 735944 single base substitution G A downstream_gene_variant BRCA-US 16 737628 737628 single base substitution C T downstream_gene_variant BTCA-JP 16 725813 725813 single base substitution A G upstream_gene_variant BTCA-JP 16 727798 727798 single base substitution C T upstream_gene_variant BTCA-JP 16 731236 731236 single base substitution G A exon_variant BTCA-JP 16 731236 731236 single base substitution G A missense_variant D10N 28G>A BTCA-JP 16 731236 731236 single base substitution G A missense_variant D63N 187G>A BTCA-JP 16 731236 731236 single base substitution G A missense_variant D82N 244G>A BTCA-JP 16 731236 731236 single base substitution G A upstream_gene_variant BTCA-JP 16 731505 731505 single base substitution G T downstream_gene_variant BTCA-JP 16 731505 731505 single base substitution G T exon_variant BTCA-JP 16 731505 731505 single base substitution G T synonymous_variant A123A 369G>T BTCA-JP 16 731505 731505 single base substitution G T synonymous_variant A142A 426G>T BTCA-JP 16 731505 731505 single base substitution G T synonymous_variant A47A 141G>T BTCA-JP 16 731505 731505 single base substitution G T synonymous_variant A70A 210G>T BTCA-JP 16 731505 731505 single base substitution G T synonymous_variant A8A 24G>T BTCA-JP 16 731505 731505 single base substitution G T upstream_gene_variant BTCA-JP 16 731512 731512 single base substitution A C downstream_gene_variant BTCA-JP 16 731512 731512 single base substitution A C exon_variant BTCA-JP 16 731512 731512 single base substitution A C missense_variant K11Q 31A>C BTCA-JP 16 731512 731512 single base substitution A C missense_variant K126Q 376A>C BTCA-JP 16 731512 731512 single base substitution A C missense_variant K145Q 433A>C BTCA-JP 16 731512 731512 single base substitution A C missense_variant K50Q 148A>C BTCA-JP 16 731512 731512 single base substitution A C missense_variant K73Q 217A>C BTCA-JP 16 731512 731512 single base substitution A C upstream_gene_variant BTCA-JP 16 732984 732984 single base substitution C T downstream_gene_variant BTCA-JP 16 733159 733159 single base substitution G A downstream_gene_variant BTCA-JP 16 734704 734704 single base substitution G A downstream_gene_variant BTCA-JP 16 737261 737261 single base substitution A G downstream_gene_variant CESC-US 16 731466 731466 single base substitution G A downstream_gene_variant CESC-US 16 731466 731466 single base substitution G A exon_variant CESC-US 16 731466 731466 single base substitution G A synonymous_variant L110L 330G>A CESC-US 16 731466 731466 single base substitution G A synonymous_variant L129L 387G>A CESC-US 16 731466 731466 single base substitution G A synonymous_variant L34L 102G>A CESC-US 16 731466 731466 single base substitution G A synonymous_variant L57L 171G>A CESC-US 16 731466 731466 single base substitution G A upstream_gene_variant CESC-US 16 736989 736989 single base substitution C T downstream_gene_variant CESC-US 16 737621 737621 single base substitution C T downstream_gene_variant CLLE-ES 16 737354 737354 single base substitution C T downstream_gene_variant CLLE-ES 16 737825 737825 single base substitution A T downstream_gene_variant COAD-US 16 726297 726297 insertion of <=200bp - C upstream_gene_variant COAD-US 16 726705 726705 single base substitution G A upstream_gene_variant COAD-US 16 731333 731333 single base substitution T C exon_variant COAD-US 16 731333 731333 single base substitution T C missense_variant I114T 341T>C COAD-US 16 731333 731333 single base substitution T C missense_variant I19T 56T>C COAD-US 16 731333 731333 single base substitution T C missense_variant I42T 125T>C COAD-US 16 731333 731333 single base substitution T C missense_variant I95T 284T>C COAD-US 16 731333 731333 single base substitution T C upstream_gene_variant COAD-US 16 731452 731452 single base substitution A G downstream_gene_variant COAD-US 16 731452 731452 single base substitution A G exon_variant COAD-US 16 731452 731452 single base substitution A G missense_variant K106E 316A>G COAD-US 16 731452 731452 single base substitution A G missense_variant K125E 373A>G COAD-US 16 731452 731452 single base substitution A G missense_variant K30E 88A>G COAD-US 16 731452 731452 single base substitution A G missense_variant K53E 157A>G COAD-US 16 731452 731452 single base substitution A G upstream_gene_variant COAD-US 16 731503 731503 single base substitution G A downstream_gene_variant COAD-US 16 731503 731503 single base substitution G A exon_variant COAD-US 16 731503 731503 single base substitution G A missense_variant A123T 367G>A COAD-US 16 731503 731503 single base substitution G A missense_variant A142T 424G>A COAD-US 16 731503 731503 single base substitution G A missense_variant A47T 139G>A COAD-US 16 731503 731503 single base substitution G A missense_variant A70T 208G>A COAD-US 16 731503 731503 single base substitution G A missense_variant A8T 22G>A COAD-US 16 731503 731503 single base substitution G A upstream_gene_variant COAD-US 16 731505 731507 deletion of <=200bp GAA - downstream_gene_variant COAD-US 16 731505 731507 deletion of <=200bp GAA - exon_variant COAD-US 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK123A COAD-US 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK142A COAD-US 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK47A COAD-US 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK70A COAD-US 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK8A COAD-US 16 731505 731507 deletion of <=200bp GAA - upstream_gene_variant COAD-US 16 731539 731539 single base substitution C T downstream_gene_variant COAD-US 16 731539 731539 single base substitution C T exon_variant COAD-US 16 731539 731539 single base substitution C T missense_variant R135C 403C>T COAD-US 16 731539 731539 single base substitution C T missense_variant R154C 460C>T COAD-US 16 731539 731539 single base substitution C T missense_variant R20C 58C>T COAD-US 16 731539 731539 single base substitution C T missense_variant R59C 175C>T COAD-US 16 731539 731539 single base substitution C T missense_variant R82C 244C>T COAD-US 16 731539 731539 single base substitution C T upstream_gene_variant COAD-US 16 732019 732019 single base substitution G T downstream_gene_variant COAD-US 16 732019 732019 single base substitution G T exon_variant COAD-US 16 732019 732019 single base substitution G T intron_variant COAD-US 16 732019 732019 single base substitution G T splice_acceptor_variant COAD-US 16 732019 732019 single base substitution G T upstream_gene_variant COAD-US 16 732800 732800 single base substitution G A downstream_gene_variant COAD-US 16 732800 732800 single base substitution G A intron_variant COAD-US 16 732993 732993 single base substitution G A downstream_gene_variant COAD-US 16 735686 735686 single base substitution G A downstream_gene_variant COAD-US 16 735921 735921 single base substitution T C downstream_gene_variant COAD-US 16 735946 735946 single base substitution C T downstream_gene_variant COAD-US 16 736959 736959 single base substitution G A downstream_gene_variant COAD-US 16 737269 737269 single base substitution C T downstream_gene_variant COAD-US 16 737323 737323 single base substitution G A downstream_gene_variant COAD-US 16 737726 737726 single base substitution G A downstream_gene_variant COCA-CN 16 726366 726366 single base substitution G A upstream_gene_variant COCA-CN 16 727043 727043 single base substitution A G upstream_gene_variant COCA-CN 16 727364 727364 single base substitution C T upstream_gene_variant COCA-CN 16 728054 728054 single base substitution C T upstream_gene_variant COCA-CN 16 730569 730569 single base substitution C T 5_prime_UTR_premature_start_codon_gain_variant COCA-CN 16 730569 730569 single base substitution C T exon_variant COCA-CN 16 730569 730569 single base substitution C T missense_variant A15V 44C>T COCA-CN 16 730569 730569 single base substitution C T upstream_gene_variant COCA-CN 16 732252 732252 single base substitution G A downstream_gene_variant COCA-CN 16 732252 732252 single base substitution G A exon_variant COCA-CN 16 732252 732252 single base substitution G A missense_variant D106N 316G>A COCA-CN 16 732252 732252 single base substitution G A missense_variant D158N 472G>A COCA-CN 16 732252 732252 single base substitution G A missense_variant D181N 541G>A COCA-CN 16 732252 732252 single base substitution G A missense_variant D253N 757G>A COCA-CN 16 732252 732252 single base substitution G A upstream_gene_variant COCA-CN 16 732391 732391 single base substitution C T 3_prime_UTR_variant COCA-CN 16 732391 732391 single base substitution C T downstream_gene_variant COCA-CN 16 732391 732391 single base substitution C T exon_variant COCA-CN 16 732391 732391 single base substitution C T missense_variant R125W 373C>T COCA-CN 16 732391 732391 single base substitution C T missense_variant R200W 598C>T COCA-CN 16 732391 732391 single base substitution C T missense_variant R272W 814C>T COCA-CN 16 732391 732391 single base substitution C T upstream_gene_variant COCA-CN 16 732711 732711 single base substitution C T 3_prime_UTR_variant COCA-CN 16 732711 732711 single base substitution C T downstream_gene_variant COCA-CN 16 732711 732711 single base substitution C T exon_variant COCA-CN 16 732711 732711 single base substitution C T intron_variant COCA-CN 16 732985 732985 single base substitution G A downstream_gene_variant COCA-CN 16 735194 735194 single base substitution C T downstream_gene_variant COCA-CN 16 735386 735386 single base substitution G A downstream_gene_variant COCA-CN 16 736045 736045 single base substitution G A downstream_gene_variant COCA-CN 16 736913 736913 single base substitution G T downstream_gene_variant COCA-CN 16 737377 737377 single base substitution C A downstream_gene_variant COCA-CN 16 737768 737768 single base substitution G A downstream_gene_variant ESAD-UK 16 725278 725278 single base substitution A G upstream_gene_variant ESAD-UK 16 730303 730303 single base substitution C T 5_prime_UTR_premature_start_codon_gain_variant ESAD-UK 16 730303 730303 single base substitution C T upstream_gene_variant ESAD-UK 16 731597 731597 single base substitution G A downstream_gene_variant ESAD-UK 16 731597 731597 single base substitution G A exon_variant ESAD-UK 16 731597 731597 single base substitution G A missense_variant R101H 302G>A ESAD-UK 16 731597 731597 single base substitution G A missense_variant R154H 461G>A ESAD-UK 16 731597 731597 single base substitution G A missense_variant R173H 518G>A ESAD-UK 16 731597 731597 single base substitution G A missense_variant R39H 116G>A ESAD-UK 16 731597 731597 single base substitution G A missense_variant R78H 233G>A ESAD-UK 16 731597 731597 single base substitution G A upstream_gene_variant ESAD-UK 16 735295 735295 single base substitution C T downstream_gene_variant ESAD-UK 16 737085 737085 single base substitution C T downstream_gene_variant ESAD-UK 16 737088 737088 single base substitution C T downstream_gene_variant ESAD-UK 16 737582 737582 single base substitution G T downstream_gene_variant ESAD-UK 16 737687 737687 single base substitution G T downstream_gene_variant ESCA-CN 16 726039 726039 single base substitution A G upstream_gene_variant ESCA-CN 16 733396 733396 single base substitution G C downstream_gene_variant ESCA-CN 16 734141 734141 single base substitution G A downstream_gene_variant ESCA-CN 16 735748 735748 single base substitution C T downstream_gene_variant ESCA-CN 16 736953 736953 single base substitution G A downstream_gene_variant GBM-US 16 726867 726867 single base substitution G A upstream_gene_variant GBM-US 16 727080 727080 single base substitution G A upstream_gene_variant GBM-US 16 727863 727863 single base substitution G A upstream_gene_variant GBM-US 16 731823 731823 single base substitution G T downstream_gene_variant GBM-US 16 731823 731823 single base substitution G T exon_variant GBM-US 16 731823 731823 single base substitution G T missense_variant E113D 339G>T GBM-US 16 731823 731823 single base substitution G T missense_variant E166D 498G>T GBM-US 16 731823 731823 single base substitution G T missense_variant E185D 555G>T GBM-US 16 731823 731823 single base substitution G T missense_variant E51D 153G>T GBM-US 16 731823 731823 single base substitution G T missense_variant E90D 270G>T GBM-US 16 731823 731823 single base substitution G T upstream_gene_variant KIRC-US 16 726989 726989 insertion of <=200bp - AA upstream_gene_variant KIRP-US 16 732019 732019 single base substitution G T downstream_gene_variant KIRP-US 16 732019 732019 single base substitution G T exon_variant KIRP-US 16 732019 732019 single base substitution G T intron_variant KIRP-US 16 732019 732019 single base substitution G T splice_acceptor_variant KIRP-US 16 732019 732019 single base substitution G T upstream_gene_variant LAML-KR 16 735794 735794 single base substitution A G downstream_gene_variant LAML-KR 16 735921 735921 single base substitution T C downstream_gene_variant LICA-CN 16 727800 727800 single base substitution G T upstream_gene_variant LICA-FR 16 726120 726120 single base substitution G C upstream_gene_variant LICA-FR 16 726393 726393 single base substitution C T upstream_gene_variant LICA-FR 16 731505 731507 deletion of <=200bp GAA - downstream_gene_variant LICA-FR 16 731505 731507 deletion of <=200bp GAA - exon_variant LICA-FR 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK123A LICA-FR 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK142A LICA-FR 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK47A LICA-FR 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK70A LICA-FR 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK8A LICA-FR 16 731505 731507 deletion of <=200bp GAA - upstream_gene_variant LICA-FR 16 733021 733021 insertion of <=200bp - G downstream_gene_variant LICA-FR 16 737603 737603 single base substitution G C downstream_gene_variant LIHC-US 16 726998 726998 single base substitution C T upstream_gene_variant LIHC-US 16 727801 727801 insertion of <=200bp - A upstream_gene_variant LIHC-US 16 732214 732214 single base substitution T C downstream_gene_variant LIHC-US 16 732214 732214 single base substitution T C exon_variant LIHC-US 16 732214 732214 single base substitution T C missense_variant M145T 434T>C LIHC-US 16 732214 732214 single base substitution T C missense_variant M168T 503T>C LIHC-US 16 732214 732214 single base substitution T C missense_variant M240T 719T>C LIHC-US 16 732214 732214 single base substitution T C missense_variant M93T 278T>C LIHC-US 16 732214 732214 single base substitution T C upstream_gene_variant LIHC-US 16 733364 733364 single base substitution C T downstream_gene_variant LIHC-US 16 735892 735892 single base substitution G A downstream_gene_variant LIHC-US 16 736891 736891 single base substitution A G downstream_gene_variant LIHC-US 16 737415 737415 single base substitution C T downstream_gene_variant LINC-JP 16 725813 725813 single base substitution A G upstream_gene_variant LINC-JP 16 726791 726791 single base substitution C A upstream_gene_variant LINC-JP 16 731505 731507 deletion of <=200bp GAA - downstream_gene_variant LINC-JP 16 731505 731507 deletion of <=200bp GAA - exon_variant LINC-JP 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK123A LINC-JP 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK142A LINC-JP 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK47A LINC-JP 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK70A LINC-JP 16 731505 731507 deletion of <=200bp GAA - inframe_deletion AK8A LINC-JP 16 731505 731507 deletion of <=200bp GAA - upstream_gene_variant LINC-JP 16 731903 731903 single base substitution T G downstream_gene_variant LINC-JP 16 731903 731903 single base substitution T G exon_variant LINC-JP 16 731903 731903 single base substitution T G intron_variant LINC-JP 16 731903 731903 single base substitution T G splice_region_variant LINC-JP 16 731903 731903 single base substitution T G upstream_gene_variant LINC-JP 16 736849 736849 single base substitution C A downstream_gene_variant LINC-JP 16 737666 737666 single base substitution G T downstream_gene_variant LINC-JP 16 737774 737774 single base substitution G A downstream_gene_variant LIRI-JP 16 730913 730913 single base substitution C T exon_variant LIRI-JP 16 730913 730913 single base substitution C T intron_variant LIRI-JP 16 730913 730913 single base substitution C T upstream_gene_variant LIRI-JP 16 732558 732558 single base substitution A T 3_prime_UTR_variant LIRI-JP 16 732558 732558 single base substitution A T downstream_gene_variant LIRI-JP 16 732558 732558 single base substitution A T exon_variant LIRI-JP 16 732563 732563 single base substitution A G 3_prime_UTR_variant LIRI-JP 16 732563 732563 single base substitution A G downstream_gene_variant LIRI-JP 16 732563 732563 single base substitution A G exon_variant LIRI-JP 16 732735 732735 single base substitution C T 3_prime_UTR_variant LIRI-JP 16 732735 732735 single base substitution C T downstream_gene_variant LIRI-JP 16 732735 732735 single base substitution C T intron_variant LUSC-KR 16 730010 730010 single base substitution G T upstream_gene_variant LUSC-US 16 726323 726323 single base substitution C T upstream_gene_variant LUSC-US 16 735761 735761 single base substitution G A downstream_gene_variant LUSC-US 16 737632 737632 single base substitution C T downstream_gene_variant MALY-DE 16 733775 733775 single base substitution G A downstream_gene_variant MALY-DE 16 733794 733794 single base substitution G A downstream_gene_variant MALY-DE 16 735165 735165 single base substitution G A downstream_gene_variant MALY-DE 16 735271 735271 single base substitution C G downstream_gene_variant MELA-AU 16 725431 725431 single base substitution G A upstream_gene_variant MELA-AU 16 726372 726372 single base substitution G A upstream_gene_variant MELA-AU 16 726565 726565 single base substitution C T upstream_gene_variant MELA-AU 16 726698 726698 single base substitution C T upstream_gene_variant MELA-AU 16 727241 727241 single base substitution C T upstream_gene_variant MELA-AU 16 729425 729425 single base substitution C T upstream_gene_variant MELA-AU 16 729431 729431 single base substitution G A upstream_gene_variant MELA-AU 16 729485 729485 single base substitution C T upstream_gene_variant MELA-AU 16 730388 730389 multiple base substitution (>=2bp and <=200bp) CC TT 5_prime_UTR_variant MELA-AU 16 730388 730389 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 16 731162 731162 single base substitution C T 5_prime_UTR_premature_start_codon_gain_variant MELA-AU 16 731162 731162 single base substitution C T exon_variant MELA-AU 16 731162 731162 single base substitution C T intron_variant MELA-AU 16 731162 731162 single base substitution C T missense_variant P57L 170C>T MELA-AU 16 731162 731162 single base substitution C T upstream_gene_variant MELA-AU 16 731754 731754 single base substitution G C downstream_gene_variant MELA-AU 16 731754 731754 single base substitution G C intron_variant MELA-AU 16 731754 731754 single base substitution G C upstream_gene_variant MELA-AU 16 731894 731894 single base substitution C T downstream_gene_variant MELA-AU 16 731894 731894 single base substitution C T exon_variant MELA-AU 16 731894 731894 single base substitution C T intron_variant MELA-AU 16 731894 731894 single base substitution C T upstream_gene_variant MELA-AU 16 732243 732243 single base substitution A G downstream_gene_variant MELA-AU 16 732243 732243 single base substitution A G exon_variant MELA-AU 16 732243 732243 single base substitution A G missense_variant I103V 307A>G MELA-AU 16 732243 732243 single base substitution A G missense_variant I155V 463A>G MELA-AU 16 732243 732243 single base substitution A G missense_variant I178V 532A>G MELA-AU 16 732243 732243 single base substitution A G missense_variant I250V 748A>G MELA-AU 16 732243 732243 single base substitution A G upstream_gene_variant MELA-AU 16 734423 734423 single base substitution G A downstream_gene_variant MELA-AU 16 734464 734464 single base substitution G A downstream_gene_variant MELA-AU 16 735231 735231 deletion of <=200bp G - downstream_gene_variant MELA-AU 16 735542 735542 single base substitution G A downstream_gene_variant MELA-AU 16 736708 736708 single base substitution G A downstream_gene_variant MELA-AU 16 736949 736949 single base substitution G A downstream_gene_variant MELA-AU 16 737292 737292 single base substitution C T downstream_gene_variant MELA-AU 16 737423 737423 single base substitution G A downstream_gene_variant MELA-AU 16 737820 737820 single base substitution C A downstream_gene_variant ORCA-IN 16 733860 733860 single base substitution C A downstream_gene_variant ORCA-IN 16 735678 735678 single base substitution C T downstream_gene_variant OV-AU 16 726315 726331 deletion of <=200bp GCTGGCGGCTCCTCACT - upstream_gene_variant OV-AU 16 737082 737082 single base substitution T C downstream_gene_variant PACA-AU 16 736146 736146 single base substitution C T downstream_gene_variant PACA-AU 16 736389 736390 deletion of <=200bp AG - downstream_gene_variant PACA-AU 16 737683 737683 single base substitution C T downstream_gene_variant PACA-CA 16 729174 729174 single base substitution C T upstream_gene_variant PACA-CA 16 730156 730156 single base substitution C T upstream_gene_variant PACA-CA 16 731774 731774 single base substitution G A downstream_gene_variant PACA-CA 16 731774 731774 single base substitution G A intron_variant PACA-CA 16 731774 731774 single base substitution G A upstream_gene_variant PACA-CA 16 733123 733123 single base substitution T C downstream_gene_variant PACA-CA 16 734115 734115 single base substitution A G downstream_gene_variant PACA-CA 16 735491 735491 single base substitution C T downstream_gene_variant PACA-CA 16 735559 735559 single base substitution G C downstream_gene_variant PACA-CA 16 736797 736797 single base substitution C A downstream_gene_variant PACA-CA 16 737182 737182 single base substitution G A downstream_gene_variant PBCA-DE 16 734115 734115 single base substitution A C downstream_gene_variant PRAD-CA 16 728500 728500 single base substitution C T upstream_gene_variant PRAD-UK 16 731525 731525 single base substitution G A downstream_gene_variant PRAD-UK 16 731525 731525 single base substitution G A exon_variant PRAD-UK 16 731525 731525 single base substitution G A missense_variant S130N 389G>A PRAD-UK 16 731525 731525 single base substitution G A missense_variant S149N 446G>A PRAD-UK 16 731525 731525 single base substitution G A missense_variant S15N 44G>A PRAD-UK 16 731525 731525 single base substitution G A missense_variant S54N 161G>A PRAD-UK 16 731525 731525 single base substitution G A missense_variant S77N 230G>A PRAD-UK 16 731525 731525 single base substitution G A upstream_gene_variant PRAD-US 16 733031 733031 single base substitution C T downstream_gene_variant PRAD-US 16 734790 734790 single base substitution G C downstream_gene_variant RECA-EU 16 725355 725355 single base substitution G C upstream_gene_variant RECA-EU 16 735921 735921 single base substitution T C downstream_gene_variant SKCA-BR 16 725239 725239 single base substitution T G upstream_gene_variant SKCA-BR 16 725249 725249 single base substitution C G upstream_gene_variant SKCA-BR 16 725256 725256 single base substitution A G upstream_gene_variant SKCA-BR 16 726579 726579 single base substitution T G upstream_gene_variant SKCA-BR 16 727222 727222 single base substitution T G upstream_gene_variant SKCA-BR 16 727243 727243 single base substitution A C upstream_gene_variant SKCA-BR 16 727410 727410 single base substitution G C upstream_gene_variant SKCA-BR 16 727438 727438 single base substitution A C upstream_gene_variant SKCA-BR 16 730253 730253 single base substitution T C 5_prime_UTR_variant SKCA-BR 16 730253 730253 single base substitution T C upstream_gene_variant SKCA-BR 16 730528 730528 single base substitution G A 5_prime_UTR_variant SKCA-BR 16 730528 730528 single base substitution G A exon_variant SKCA-BR 16 730528 730528 single base substitution G A start_lost M1I 3G>A SKCA-BR 16 730528 730528 single base substitution G A upstream_gene_variant SKCA-BR 16 731615 731615 single base substitution A C downstream_gene_variant SKCA-BR 16 731615 731615 single base substitution A C intron_variant SKCA-BR 16 731615 731615 single base substitution A C upstream_gene_variant SKCA-BR 16 734427 734427 single base substitution G A downstream_gene_variant SKCA-BR 16 734693 734693 single base substitution T G downstream_gene_variant SKCA-BR 16 736000 736000 single base substitution G A downstream_gene_variant SKCA-BR 16 736558 736558 insertion of <=200bp - TCTGGCCCACCCTGGAGCC downstream_gene_variant SKCM-US 16 726311 726311 single base substitution C T upstream_gene_variant SKCM-US 16 726698 726698 single base substitution C T upstream_gene_variant SKCM-US 16 727045 727045 single base substitution G A upstream_gene_variant SKCM-US 16 727513 727513 single base substitution G A upstream_gene_variant SKCM-US 16 727788 727788 single base substitution C A upstream_gene_variant SKCM-US 16 731277 731277 single base substitution G A 5_prime_UTR_variant SKCM-US 16 731277 731277 single base substitution G A exon_variant SKCM-US 16 731277 731277 single base substitution G A synonymous_variant K23K 69G>A SKCM-US 16 731277 731277 single base substitution G A synonymous_variant K76K 228G>A SKCM-US 16 731277 731277 single base substitution G A synonymous_variant K95K 285G>A SKCM-US 16 731277 731277 single base substitution G A upstream_gene_variant SKCM-US 16 731537 731537 single base substitution G A downstream_gene_variant SKCM-US 16 731537 731537 single base substitution G A exon_variant SKCM-US 16 731537 731537 single base substitution G A missense_variant R134Q 401G>A SKCM-US 16 731537 731537 single base substitution G A missense_variant R153Q 458G>A SKCM-US 16 731537 731537 single base substitution G A missense_variant R19Q 56G>A SKCM-US 16 731537 731537 single base substitution G A missense_variant R58Q 173G>A SKCM-US 16 731537 731537 single base substitution G A missense_variant R81Q 242G>A SKCM-US 16 731537 731537 single base substitution G A upstream_gene_variant SKCM-US 16 734758 734758 single base substitution G A downstream_gene_variant SKCM-US 16 735547 735547 single base substitution C T downstream_gene_variant SKCM-US 16 735959 735959 single base substitution C T downstream_gene_variant SKCM-US 16 736754 736754 single base substitution C T downstream_gene_variant SKCM-US 16 736958 736958 single base substitution C T downstream_gene_variant SKCM-US 16 737365 737365 single base substitution C T downstream_gene_variant SKCM-US 16 737679 737679 single base substitution G A downstream_gene_variant SKCM-US 16 737699 737699 single base substitution C T downstream_gene_variant STAD-US 16 726267 726267 single base substitution C A upstream_gene_variant STAD-US 16 726836 726836 single base substitution C T upstream_gene_variant STAD-US 16 727109 727109 single base substitution A G upstream_gene_variant STAD-US 16 727688 727688 single base substitution C A upstream_gene_variant STAD-US 16 727934 727934 single base substitution G A upstream_gene_variant STAD-US 16 731217 731217 single base substitution G A exon_variant STAD-US 16 731217 731217 single base substitution G A synonymous_variant Q3Q 9G>A STAD-US 16 731217 731217 single base substitution G A synonymous_variant Q56Q 168G>A STAD-US 16 731217 731217 single base substitution G A synonymous_variant Q75Q 225G>A STAD-US 16 731217 731217 single base substitution G A upstream_gene_variant STAD-US 16 731318 731318 single base substitution G A exon_variant STAD-US 16 731318 731318 single base substitution G A missense_variant S109N 326G>A STAD-US 16 731318 731318 single base substitution G A missense_variant S14N 41G>A STAD-US 16 731318 731318 single base substitution G A missense_variant S37N 110G>A STAD-US 16 731318 731318 single base substitution G A missense_variant S90N 269G>A STAD-US 16 731318 731318 single base substitution G A upstream_gene_variant STAD-US 16 731592 731592 single base substitution G A downstream_gene_variant STAD-US 16 731592 731592 single base substitution G A exon_variant STAD-US 16 731592 731592 single base substitution G A synonymous_variant A152A 456G>A STAD-US 16 731592 731592 single base substitution G A synonymous_variant A171A 513G>A STAD-US 16 731592 731592 single base substitution G A synonymous_variant A37A 111G>A STAD-US 16 731592 731592 single base substitution G A synonymous_variant A76A 228G>A STAD-US 16 731592 731592 single base substitution G A synonymous_variant A99A 297G>A STAD-US 16 731592 731592 single base substitution G A upstream_gene_variant STAD-US 16 731803 731803 single base substitution G C downstream_gene_variant STAD-US 16 731803 731803 single base substitution G C exon_variant STAD-US 16 731803 731803 single base substitution G C missense_variant E107Q 319G>C STAD-US 16 731803 731803 single base substitution G C missense_variant E160Q 478G>C STAD-US 16 731803 731803 single base substitution G C missense_variant E179Q 535G>C STAD-US 16 731803 731803 single base substitution G C missense_variant E45Q 133G>C STAD-US 16 731803 731803 single base substitution G C missense_variant E84Q 250G>C STAD-US 16 731803 731803 single base substitution G C upstream_gene_variant STAD-US 16 732036 732036 single base substitution A C downstream_gene_variant STAD-US 16 732036 732036 single base substitution A C exon_variant STAD-US 16 732036 732036 single base substitution A C intron_variant STAD-US 16 732036 732036 single base substitution A C missense_variant D115A 344A>C STAD-US 16 732036 732036 single base substitution A C missense_variant D138A 413A>C STAD-US 16 732036 732036 single base substitution A C missense_variant D191A 572A>C STAD-US 16 732036 732036 single base substitution A C missense_variant D210A 629A>C STAD-US 16 732036 732036 single base substitution A C upstream_gene_variant STAD-US 16 732226 732226 single base substitution G A downstream_gene_variant STAD-US 16 732226 732226 single base substitution G A exon_variant STAD-US 16 732226 732226 single base substitution G A missense_variant C149Y 446G>A STAD-US 16 732226 732226 single base substitution G A missense_variant C172Y 515G>A STAD-US 16 732226 732226 single base substitution G A missense_variant C244Y 731G>A STAD-US 16 732226 732226 single base substitution G A missense_variant C97Y 290G>A STAD-US 16 732226 732226 single base substitution G A upstream_gene_variant STAD-US 16 733072 733072 single base substitution G A downstream_gene_variant STAD-US 16 733220 733220 deletion of <=200bp C - downstream_gene_variant STAD-US 16 735396 735396 single base substitution C T downstream_gene_variant STAD-US 16 735692 735692 single base substitution C T downstream_gene_variant STAD-US 16 736817 736817 single base substitution G A downstream_gene_variant STAD-US 16 737013 737013 single base substitution C T downstream_gene_variant STAD-US 16 737628 737628 single base substitution C T downstream_gene_variant THCA-US 16 732365 732365 single base substitution G A 3_prime_UTR_variant THCA-US 16 732365 732365 single base substitution G A downstream_gene_variant THCA-US 16 732365 732365 single base substitution G A missense_variant R116H 347G>A THCA-US 16 732365 732365 single base substitution G A missense_variant R191H 572G>A THCA-US 16 732365 732365 single base substitution G A missense_variant R263H 788G>A THCA-US 16 732365 732365 single base substitution G A splice_region_variant THCA-US 16 732365 732365 single base substitution G A upstream_gene_variant UCEC-US 16 727946 727946 single base substitution G A upstream_gene_variant UCEC-US 16 732233 732233 single base substitution G A downstream_gene_variant UCEC-US 16 732233 732233 single base substitution G A exon_variant UCEC-US 16 732233 732233 single base substitution G A synonymous_variant T151T 453G>A UCEC-US 16 732233 732233 single base substitution G A synonymous_variant T174T 522G>A UCEC-US 16 732233 732233 single base substitution G A synonymous_variant T246T 738G>A UCEC-US 16 732233 732233 single base substitution G A synonymous_variant T99T 297G>A UCEC-US 16 732233 732233 single base substitution G A upstream_gene_variant UCEC-US 16 732452 732452 single base substitution C T 3_prime_UTR_variant UCEC-US 16 732452 732452 single base substitution C T downstream_gene_variant UCEC-US 16 732452 732452 single base substitution C T exon_variant UCEC-US 16 732452 732452 single base substitution C T missense_variant A145V 434C>T UCEC-US 16 732452 732452 single base substitution C T missense_variant A220V 659C>T UCEC-US 16 732452 732452 single base substitution C T missense_variant A292V 875C>T UCEC-US 16 733166 733166 single base substitution C T downstream_gene_variant UCEC-US 16 735053 735053 single base substitution G T downstream_gene_variant UCEC-US 16 735512 735512 single base substitution C T downstream_gene_variant UCEC-US 16 736079 736079 single base substitution C T downstream_gene_variant UCEC-US 16 736816 736816 single base substitution C T downstream_gene_variant UCEC-US 16 737174 737174 single base substitution G A downstream_gene_variant UCEC-US 16 737359 737359 single base substitution C T downstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-IH-A3EA-01 COSM3512099 c.285G>A p.K95K Substitution - coding silent 16:681277-681277 + TCGA-BR-8591-01 COSM4062737 c.326G>A p.S109N Substitution - Missense 16:681318-681318 + TCGA-F1-6177-01 COSM4062736 c.225G>A p.Q75Q Substitution - coding silent 16:681217-681217 + TCGA-AD-6895-01 COSM435760 c.426_428delGAA p.K145delK Deletion - In frame 16:681505-681507 + TCGA-BR-4370-01 COSM4062738 c.513G>A p.A171A Substitution - coding silent 16:681592-681592 + OVCAR-5 COSM1684424 c.863_865delAGG p.E288delE Deletion - In frame 16:682440-682442 + TCGA-CD-8529-01 COSM1302238 c.535G>C p.E179Q Substitution - Missense 16:681803-681803 + TCGA-AC-A2QH-01 COSM5833168 c.90delG p.E31fs*41 Deletion - Frameshift 16:680615-680615 + SJRHB036A COSM3737130 c.786+8delC p.? Unknown 16:682289-682289 + HN_62298 COSM129483 c.710T>C p.F237S Substitution - Missense 16:682205-682205 + TCGA-AC-A23H-01 COSM3818529 c.658G>A p.E220K Substitution - Missense 16:682065-682065 + ESCC_158 COSM5646661 c.514G>C p.E172Q Substitution - Missense 16:681593-681593 + TCGA-CA-6716-01 COSM1379122 c.613-1G>T p.? Unknown 16:682019-682019 + I2L-P19Tb-Tumor-Biopsy COSM5363469 c.528G>A p.E176E Substitution - coding silent 16:681796-681796 + TCGA-CF-A3MG-01 COSM1302239 c.840C>T p.L280L Substitution - coding silent 16:682417-682417 + 255 COSM3732252 c.874G>A p.A292T Substitution - Missense 16:682451-682451 + TCGA-C4-A0F6-01 COSM417268 c.331G>C p.D111H Substitution - Missense 16:681323-681323 + 35M COSM5582656 c.7G>A p.G3S Substitution - Missense 16:680532-680532 + sysucc-834T COSM5485820 c.814C>T p.R272W Substitution - Missense 16:682391-682391 + ESO-160 COSM1266988 c.547A>C p.N183H Substitution - Missense 16:681815-681815 + TCGA-AR-A24N-01 COSM1479082 c.597C>T p.C199C Substitution - coding silent 16:681865-681865 + TCGA-BR-8361-01 COSM4062740 c.731G>A p.C244Y Substitution - Missense 16:682226-682226 + QC2-25-T2 COSM5625157 c.418C>T p.R140* Substitution - Nonsense 16:681497-681497 + LP6005334-DNA_F03 COSM5036015 c.518G>A p.R173H Substitution - Missense 16:681597-681597 + ACINAR28 COSM1735193 c.394G>A p.G132R Substitution - Missense 16:681473-681473 + T2769 COSM3277056 c.674G>A p.R225Q Substitution - Missense 16:682169-682169 + TCGA-IA-A40U-01 COSM1379122 c.613-1G>T p.? Unknown 16:682019-682019 + TCGA-CC-5262-01 COSM4919283 c.719T>C p.M240T Substitution - Missense 16:682214-682214 + TCGA-BH-A0B6-01 COSM3818528 c.378G>A p.E126E Substitution - coding silent 16:681457-681457 + I2L-P19Tb-Tumor-Organoid COSM5363469 c.528G>A p.E176E Substitution - coding silent 16:681796-681796 + TCGA-BS-A0TA-01 COSM973571 c.875C>T p.A292V Substitution - Missense 16:682452-682452 + TCGA-AY-6197-01 COSM1379112 c.424G>A p.A142T Substitution - Missense 16:681503-681503 + YUPEET COSM1708606 c.454G>A p.E152K Substitution - Missense 16:681533-681533 + BD105T COSM5514439 c.426G>T p.A142A Substitution - coding silent 16:681505-681505 + TCGA-EK-A2RA-01 COSM4848169 c.387G>A p.L129L Substitution - coding silent 16:681466-681466 + LIM1899 COSM4640075 c.27C>T p.G9G Substitution - coding silent 16:680552-680552 + T98G COSM5713260 c.786+7delC p.? Unknown 16:682288-682288 + PD9694a COSM5789580 c.478G>A p.E160K Substitution - Missense 16:681557-681557 + TCGA-AD-5900-01 COSM1379111 c.341T>C p.I114T Substitution - Missense 16:681333-681333 + TCGA-EM-A3AP-01 COSM3370552 c.788G>A p.R263H Substitution - Missense 16:682365-682365 + TCGA-AM-5820-01 COSM3691167 c.373A>G p.K125E Substitution - Missense 16:681452-681452 + LN18 COSM5713260 c.786+7delC p.? Unknown 16:682288-682288 + TCGA-32-1982-01 COSM3402474 c.555G>T p.E185D Substitution - Missense 16:681823-681823 + 587222 COSM1227938 c.294C>A p.F98L Substitution - Missense 16:681286-681286 + sysucc-1237T COSM5764498 c.44C>T p.A15V Substitution - Missense 16:680569-680569 + TCGA-BH-A0HA-01 COSM435760 c.426_428delGAA p.K145delK Deletion - In frame 16:681505-681507 + T2991 COSM4730712 c.690_691insAGT p.Y230_L231insS Insertion - In frame 16:682185-682186 + TCGA-D1-A177-01 COSM973570 c.738G>A p.T246T Substitution - coding silent 16:682233-682233 + BCM723T COSM5347360 c.433_435delAAG p.K145delK Deletion - In frame 16:681512-681514 + TCGA-42-2587-01 COSM1324347 c.194A>T p.N65I Substitution - Missense 16:681186-681186 + CA2 COSM1166135 c.433A>C p.K145Q Substitution - Missense 16:681512-681512 + ESO-0079 COSM1266987 c.760C>A p.R254S Substitution - Missense 16:682255-682255 + T3174 COSM4730711 c.571A>C p.S191R Substitution - Missense 16:681839-681839 + 2293744 COSM1166135 c.433A>C p.K145Q Substitution - Missense 16:681512-681512 + TCGA-D7-6817-01 COSM4062739 c.629A>C p.D210A Substitution - Missense 16:682036-682036 + BD114T COSM5504151 c.244G>A p.D82N Substitution - Missense 16:681236-681236 + LUAD-NYU284 COSM372806 c.717G>C p.L239L Substitution - coding silent 16:682212-682212 + 473 COSM4438118 c.636C>T p.D212D Substitution - coding silent 16:682043-682043 + 587350 COSM1227939 c.461G>A p.R154H Substitution - Missense 16:681540-681540 + U343 COSM5713260 c.786+7delC p.? Unknown 16:682288-682288 + TCGA-D3-A51N-06 COSM3512100 c.458G>A p.R153Q Substitution - Missense 16:681537-681537 + ESCC_13 COSM5625157 c.418C>T p.R140* Substitution - Nonsense 16:681497-681497 + U87 COSM5713260 c.786+7delC p.? Unknown 16:682288-682288 + TCGA-D5-6540-01 COSM1379113 c.460C>T p.R154C Substitution - Missense 16:681539-681539 + GC_313T-GC_313N COSM4774481 c.123G>A p.K41K Substitution - coding silent 16:680648-680648 + TCGA-G2-A2EO-01 COSM1302238 c.535G>C p.E179Q Substitution - Missense 16:681803-681803 + LN229 COSM5713260 c.786+7delC p.? Unknown 16:682288-682288 + TCGA-C4-A0F6-01 COSM417267 c.796C>T p.H266Y Substitution - Missense 16:682373-682373 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.592081 16p13.3 607207 2481882|CGAP|BC007545|C/T|coding|Gln102end|402|Candidate; 2481882|CGAP|BC017178|C/T|coding|Gln102end|389|Candidate; 2481882|CGAP|BC022788|C/T|coding|Gln102end|402|Candidate; 2481882|CGAP|BC063617|C/T|coding|Gln102end|333|Candidate

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Missense p.D210A c.629A>C 16 732036 STAD A C Missense p.N183H c.547A>C 16 731815 ESCA C A Missense p.R254S c.760C>A 16 732255 ESCA C T Missense p.A292V c.875C>T 16 732452 UCEC C T Missense p.H266Y c.796C>T 16 732373 BLCA C T Missense p.P282S c.844C>T 16 732421 HNSC C T Synonymous p.F98F c.294C>T 16 731286 HNSC G A Missense p.D134N c.400G>A 16 731479 LUAD G A Missense p.R263H c.788G>A 16 732365 THCA G A Synonymous p.A171A c.513G>A 16 731592 STAD G A Synonymous p.K95K c.285G>A 16 731277 CM G A Synonymous p.Q75Q c.225G>A 16 731217 STAD G C Missense p.D111H c.331G>C 16 731323 BLCA G C Missense p.E179Q c.535G>C 16 731803 BLCA G T Missense p.E185D c.555G>T 16 731823 GBM T C Missense p.F237S c.710T>C 16 732205 HNSC