Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 8 25293948 25293948 + Nonsense_Mutation SNP C C A TCGA-DK-AA6X-01A-12D-A42E-08 TCGA-DK-AA6X-10A-01D-A42H-08 g.chr8:25293948C>A c.553G>T c.(553-555)Gaa>Taa p.E185* BRCA 8 25292958 25292958 + Missense_Mutation SNP A A G TCGA-E2-A15R-01A-11D-A10Y-09 TCGA-E2-A15R-10A-01D-A110-09 g.chr8:25292958A>G c.734T>C c.(733-735)tTa>tCa p.L245S COAD 8 25290078 25290078 + Frame_Shift_Del DEL T T - TCGA-AD-5900-01A-11D-1650-10 TCGA-AD-5900-10A-01D-1650-10 g.chr8:25290078delT c.995delA c.(994-996)aatfs p.N332fs COAD 8 25290078 25290078 + Frame_Shift_Del DEL T T - TCGA-CM-6162-01A-11D-1650-10 TCGA-CM-6162-10A-01D-1650-10 g.chr8:25290078delT c.995delA c.(994-996)aatfs p.N332fs COAD 8 25290083 25290083 + Missense_Mutation SNP T T A TCGA-AD-5900-01A-11D-1650-10 TCGA-AD-5900-10A-01D-1650-10 g.chr8:25290083T>A c.990A>T c.(988-990)ttA>ttT p.L330F COAD 8 25290090 25290090 + Missense_Mutation SNP G G A TCGA-CM-6674-01A-11D-1835-10 TCGA-CM-6674-10A-01D-1835-10 g.chr8:25290090G>A c.983C>T c.(982-984)gCt>gTt p.A328V COAD 8 25296833 25296833 + Missense_Mutation SNP T T C TCGA-A6-6781-01A-22D-1924-10 TCGA-A6-6781-10A-01D-1924-10 g.chr8:25296833T>C c.461A>G c.(460-462)cAt>cGt p.H154R COAD 8 25301823 25301823 + Nonsense_Mutation SNP C C A TCGA-G4-6628-01A-11D-1835-10 TCGA-G4-6628-10A-01D-1835-10 g.chr8:25301823C>A c.199G>T c.(199-201)Gga>Tga p.G67* COADREAD 8 25290078 25290078 + Frame_Shift_Del DEL T T - TCGA-AD-5900-01A-11D-1650-10 TCGA-AD-5900-10A-01D-1650-10 g.chr8:25290078delT c.995delA c.(994-996)aatfs p.N332fs COADREAD 8 25290078 25290078 + Frame_Shift_Del DEL T T - TCGA-CM-6162-01A-11D-1650-10 TCGA-CM-6162-10A-01D-1650-10 g.chr8:25290078delT c.995delA c.(994-996)aatfs p.N332fs COADREAD 8 25290083 25290083 + Missense_Mutation SNP T T A TCGA-AD-5900-01A-11D-1650-10 TCGA-AD-5900-10A-01D-1650-10 g.chr8:25290083T>A c.990A>T c.(988-990)ttA>ttT p.L330F COADREAD 8 25290090 25290090 + Missense_Mutation SNP G G A TCGA-CM-6674-01A-11D-1835-10 TCGA-CM-6674-10A-01D-1835-10 g.chr8:25290090G>A c.983C>T c.(982-984)gCt>gTt p.A328V COADREAD 8 25296833 25296833 + Missense_Mutation SNP T T C TCGA-A6-6781-01A-22D-1924-10 TCGA-A6-6781-10A-01D-1924-10 g.chr8:25296833T>C c.461A>G c.(460-462)cAt>cGt p.H154R COADREAD 8 25301823 25301823 + Nonsense_Mutation SNP C C A TCGA-G4-6628-01A-11D-1835-10 TCGA-G4-6628-10A-01D-1835-10 g.chr8:25301823C>A c.199G>T c.(199-201)Gga>Tga p.G67* GBM 8 25287394 25287394 + Silent SNP G G A TCGA-19-2629-01A-01D-1495-08 TCGA-19-2629-10A-01D-1495-08 g.chr8:25287394G>A c.1149C>T c.(1147-1149)caC>caT p.H383H GBMLGG 8 25287394 25287394 + Silent SNP G G A TCGA-19-2629-01A-01D-1495-08 TCGA-19-2629-10A-01D-1495-08 g.chr8:25287394G>A c.1149C>T c.(1147-1149)caC>caT p.H383H HNSC 8 25290879 25290879 + Missense_Mutation SNP C C G TCGA-CQ-7071-01A-12D-A30E-08 TCGA-CQ-7071-10A-01D-A30H-08 g.chr8:25290879C>G c.886G>C c.(886-888)Gag>Cag p.E296Q HNSC 8 25303757 25303757 + Missense_Mutation SNP C C A TCGA-CV-A6JM-01A-11D-A31L-08 TCGA-CV-A6JM-10A-01D-A31J-08 g.chr8:25303757C>A c.58G>T c.(58-60)Gta>Tta p.V20L KICH 8 25296836 25296836 + Missense_Mutation SNP C C T TCGA-KN-8428-01A-11D-2310-10 TCGA-KN-8428-11A-01D-2311-10 g.chr8:25296836C>T c.458G>A c.(457-459)cGt>cAt p.R153H KIPAN 8 25290134 25290134 + Silent SNP C C A TCGA-B0-5098-01A-01D-1421-08 TCGA-B0-5098-11A-01D-1421-08 g.chr8:25290134C>A c.939G>T c.(937-939)gtG>gtT p.V313V KIPAN 8 25296836 25296836 + Missense_Mutation SNP C C T TCGA-KN-8428-01A-11D-2310-10 TCGA-KN-8428-11A-01D-2311-10 g.chr8:25296836C>T c.458G>A c.(457-459)cGt>cAt p.R153H KIRC 8 25290134 25290134 + Silent SNP C C A TCGA-B0-5098-01A-01D-1421-08 TCGA-B0-5098-11A-01D-1421-08 g.chr8:25290134C>A c.939G>T c.(937-939)gtG>gtT p.V313V LUAD 8 25292931 25292931 + Missense_Mutation SNP T T C TCGA-17-Z030-01A-01W-0746-08 TCGA-17-Z030-11A-01W-0746-08 g.chr8:25292931T>C c.761A>G c.(760-762)aAt>aGt p.N254S LUSC 8 25293004 25293004 + Missense_Mutation SNP G G C TCGA-33-4547-01A-01D-1267-08 TCGA-33-4547-11A-01D-1267-08 g.chr8:25293004G>C c.688C>G c.(688-690)Ctt>Gtt p.L230V LUSC 8 25296837 25296837 + Missense_Mutation SNP G G A TCGA-60-2719-01A-01D-1522-08 TCGA-60-2719-11A-01D-1522-08 g.chr8:25296837G>A c.457C>T c.(457-459)Cgt>Tgt p.R153C LUSC 8 25303650 25303650 + Missense_Mutation SNP C C G TCGA-33-6737-01A-11D-1817-08 TCGA-33-6737-11A-01D-1817-08 g.chr8:25303650C>G c.165G>C c.(163-165)ttG>ttC p.L55F LUSC 8 25303661 25303661 + Missense_Mutation SNP C C T TCGA-33-6737-01A-11D-1817-08 TCGA-33-6737-11A-01D-1817-08 g.chr8:25303661C>T c.154G>A c.(154-156)Gat>Aat p.D52N LUSC 8 25315739 25315739 + Silent SNP C C T TCGA-60-2722-01A-01D-1522-08 TCGA-60-2722-11A-01D-1522-08 g.chr8:25315739C>T c.24G>A c.(22-24)ctG>ctA p.L8L PAAD 8 25293013 25293013 + Missense_Mutation SNP C C A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr8:25293013C>A c.679G>T c.(679-681)Ggt>Tgt p.G227C PAAD 8 25296876 25296876 + Silent SNP G G T TCGA-IB-A7LX-01A-12D-A36O-08 TCGA-IB-A7LX-10A-01D-A367-08 g.chr8:25296876G>T c.418C>A c.(418-420)Cga>Aga p.R140R SKCM 8 25298174 25298174 + Missense_Mutation SNP G G A TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr8:25298174G>A c.230C>T c.(229-231)tCt>tTt p.S77F

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 8 25315766 25315766 single base substitution G A 5_prime_UTR_variant BLCA-CN 8 25315766 25315766 single base substitution G A exon_variant BLCA-CN 8 25315766 25315766 single base substitution G A upstream_gene_variant BLCA-US 8 25280738 25280738 single base substitution C T downstream_gene_variant BOCA-FR 8 25319604 25319604 single base substitution A G upstream_gene_variant BRCA-EU 8 25280523 25280523 single base substitution T G downstream_gene_variant BRCA-EU 8 25282525 25282525 single base substitution T A downstream_gene_variant BRCA-EU 8 25282573 25282573 single base substitution T C downstream_gene_variant BRCA-EU 8 25285532 25285532 single base substitution A G 3_prime_UTR_variant BRCA-EU 8 25285532 25285532 single base substitution A G downstream_gene_variant BRCA-EU 8 25286172 25286172 single base substitution A T 3_prime_UTR_variant BRCA-EU 8 25286172 25286172 single base substitution A T downstream_gene_variant BRCA-EU 8 25287187 25287187 single base substitution C G 3_prime_UTR_variant BRCA-EU 8 25288728 25288728 deletion of <=200bp T - downstream_gene_variant BRCA-EU 8 25288728 25288728 deletion of <=200bp T - intron_variant BRCA-EU 8 25290456 25290456 single base substitution C G downstream_gene_variant BRCA-EU 8 25290456 25290456 single base substitution C G intron_variant BRCA-EU 8 25290869 25290869 single base substitution G A 3_prime_UTR_variant BRCA-EU 8 25290869 25290869 single base substitution G A downstream_gene_variant BRCA-EU 8 25290869 25290869 single base substitution G A missense_variant S299F 896C>T BRCA-EU 8 25295214 25295214 single base substitution A T downstream_gene_variant BRCA-EU 8 25295214 25295214 single base substitution A T intron_variant BRCA-EU 8 25297071 25297071 single base substitution A G downstream_gene_variant BRCA-EU 8 25297071 25297071 single base substitution A G intron_variant BRCA-EU 8 25297204 25297204 single base substitution G T 3_prime_UTR_variant BRCA-EU 8 25297204 25297204 single base substitution G T downstream_gene_variant BRCA-EU 8 25297204 25297204 single base substitution G T exon_variant BRCA-EU 8 25297204 25297204 single base substitution G T intron_variant BRCA-EU 8 25299754 25299754 single base substitution G C downstream_gene_variant BRCA-EU 8 25299754 25299754 single base substitution G C intron_variant BRCA-EU 8 25300085 25300085 single base substitution C T downstream_gene_variant BRCA-EU 8 25300085 25300085 single base substitution C T intron_variant BRCA-EU 8 25301326 25301326 single base substitution C T downstream_gene_variant BRCA-EU 8 25301326 25301326 single base substitution C T intron_variant BRCA-EU 8 25302959 25302959 insertion of <=200bp - A downstream_gene_variant BRCA-EU 8 25302959 25302959 insertion of <=200bp - A intron_variant BRCA-EU 8 25303513 25303513 single base substitution G T downstream_gene_variant BRCA-EU 8 25303513 25303513 single base substitution G T intron_variant BRCA-EU 8 25304092 25304092 single base substitution T A downstream_gene_variant BRCA-EU 8 25304092 25304092 single base substitution T A intron_variant BRCA-EU 8 25304729 25304729 single base substitution G A downstream_gene_variant BRCA-EU 8 25304729 25304729 single base substitution G A intron_variant BRCA-EU 8 25304761 25304761 single base substitution C G downstream_gene_variant BRCA-EU 8 25304761 25304761 single base substitution C G intron_variant BRCA-EU 8 25305265 25305265 single base substitution T C downstream_gene_variant BRCA-EU 8 25305265 25305265 single base substitution T C intron_variant BRCA-EU 8 25306026 25306026 deletion of <=200bp A - downstream_gene_variant BRCA-EU 8 25306026 25306026 deletion of <=200bp A - intron_variant BRCA-EU 8 25306738 25306738 single base substitution C T downstream_gene_variant BRCA-EU 8 25306738 25306738 single base substitution C T intron_variant BRCA-EU 8 25307236 25307236 single base substitution C G downstream_gene_variant BRCA-EU 8 25307236 25307236 single base substitution C G intron_variant BRCA-EU 8 25309293 25309293 single base substitution A G intron_variant BRCA-EU 8 25309293 25309293 single base substitution A G upstream_gene_variant BRCA-EU 8 25314379 25314379 single base substitution C T intron_variant BRCA-EU 8 25318411 25318411 single base substitution T C upstream_gene_variant BRCA-EU 8 25320369 25320369 deletion of <=200bp T - upstream_gene_variant BRCA-EU 8 25320440 25320440 single base substitution C T upstream_gene_variant BRCA-FR 8 25318750 25318750 single base substitution T C upstream_gene_variant BRCA-UK 8 25284643 25284643 single base substitution C T downstream_gene_variant BRCA-UK 8 25289432 25289432 single base substitution C G downstream_gene_variant BRCA-UK 8 25289432 25289432 single base substitution C G intron_variant BRCA-UK 8 25301326 25301326 single base substitution C T downstream_gene_variant BRCA-UK 8 25301326 25301326 single base substitution C T intron_variant BRCA-UK 8 25316448 25316448 single base substitution G A upstream_gene_variant BRCA-UK 8 25316671 25316671 single base substitution G C upstream_gene_variant BRCA-US 8 25292958 25292958 single base substitution A G 3_prime_UTR_variant BRCA-US 8 25292958 25292958 single base substitution A G downstream_gene_variant BRCA-US 8 25292958 25292958 single base substitution A G missense_variant L245S 734T>C BRCA-US 8 25319576 25319576 single base substitution C T upstream_gene_variant BRCA-US 8 25319710 25319710 single base substitution G C upstream_gene_variant BTCA-JP 8 25280703 25280703 single base substitution T C downstream_gene_variant BTCA-JP 8 25290078 25290078 deletion of <=200bp T - 3_prime_UTR_variant BTCA-JP 8 25290078 25290078 deletion of <=200bp T - downstream_gene_variant BTCA-JP 8 25290078 25290078 deletion of <=200bp T - frameshift_variant N332 BTCA-JP 8 25291023 25291023 insertion of <=200bp - A downstream_gene_variant BTCA-JP 8 25291023 25291023 insertion of <=200bp - A intron_variant CESC-US 8 25317769 25317769 single base substitution C G upstream_gene_variant CESC-US 8 25319603 25319603 single base substitution G A upstream_gene_variant CLLE-ES 8 25292969 25292969 single base substitution T A 3_prime_UTR_variant CLLE-ES 8 25292969 25292969 single base substitution T A downstream_gene_variant CLLE-ES 8 25292969 25292969 single base substitution T A missense_variant K241N 723A>T CLLE-ES 8 25295397 25295397 single base substitution A C downstream_gene_variant CLLE-ES 8 25295397 25295397 single base substitution A C intron_variant CLLE-ES 8 25304191 25304191 single base substitution G A downstream_gene_variant CLLE-ES 8 25304191 25304191 single base substitution G A intron_variant CLLE-ES 8 25307115 25307115 single base substitution A C downstream_gene_variant CLLE-ES 8 25307115 25307115 single base substitution A C intron_variant CLLE-ES 8 25307352 25307352 single base substitution G A downstream_gene_variant CLLE-ES 8 25307352 25307352 single base substitution G A intron_variant COAD-US 8 25280756 25280756 single base substitution G A downstream_gene_variant COAD-US 8 25287397 25287397 single base substitution T C 3_prime_UTR_variant COAD-US 8 25287397 25287397 single base substitution T C synonymous_variant L382L 1146A>G COAD-US 8 25290078 25290078 deletion of <=200bp T - 3_prime_UTR_variant COAD-US 8 25290078 25290078 deletion of <=200bp T - downstream_gene_variant COAD-US 8 25290078 25290078 deletion of <=200bp T - frameshift_variant N332 COAD-US 8 25290090 25290090 single base substitution G A 3_prime_UTR_variant COAD-US 8 25290090 25290090 single base substitution G A downstream_gene_variant COAD-US 8 25290090 25290090 single base substitution G A missense_variant A328V 983C>T COAD-US 8 25296833 25296833 single base substitution T C 3_prime_UTR_variant COAD-US 8 25296833 25296833 single base substitution T C downstream_gene_variant COAD-US 8 25296833 25296833 single base substitution T C exon_variant COAD-US 8 25296833 25296833 single base substitution T C missense_variant H154R 461A>G COAD-US 8 25301823 25301823 single base substitution C A downstream_gene_variant COAD-US 8 25301823 25301823 single base substitution C A exon_variant COAD-US 8 25301823 25301823 single base substitution C A intron_variant COAD-US 8 25301823 25301823 single base substitution C A stop_gained G67* 199G>T COCA-CN 8 25280844 25280844 single base substitution C T downstream_gene_variant COCA-CN 8 25287615 25287615 single base substitution C T intron_variant COCA-CN 8 25297606 25297606 single base substitution A G downstream_gene_variant COCA-CN 8 25297606 25297606 single base substitution A G intron_variant COCA-CN 8 25317954 25317954 single base substitution C T upstream_gene_variant ESAD-UK 8 25282550 25282550 single base substitution A G downstream_gene_variant ESAD-UK 8 25285720 25285720 single base substitution T G 3_prime_UTR_variant ESAD-UK 8 25285720 25285720 single base substitution T G downstream_gene_variant ESAD-UK 8 25287178 25287178 single base substitution G T 3_prime_UTR_variant ESAD-UK 8 25288580 25288580 single base substitution C G downstream_gene_variant ESAD-UK 8 25288580 25288580 single base substitution C G intron_variant ESAD-UK 8 25292076 25292076 single base substitution C T downstream_gene_variant ESAD-UK 8 25292076 25292076 single base substitution C T intron_variant ESAD-UK 8 25293939 25293939 single base substitution T C 3_prime_UTR_variant ESAD-UK 8 25293939 25293939 single base substitution T C downstream_gene_variant ESAD-UK 8 25293939 25293939 single base substitution T C exon_variant ESAD-UK 8 25293939 25293939 single base substitution T C missense_variant I188V 562A>G ESAD-UK 8 25295676 25295676 single base substitution G A downstream_gene_variant ESAD-UK 8 25295676 25295676 single base substitution G A intron_variant ESAD-UK 8 25297037 25297037 single base substitution G A downstream_gene_variant ESAD-UK 8 25297037 25297037 single base substitution G A intron_variant ESAD-UK 8 25299768 25299768 single base substitution A G downstream_gene_variant ESAD-UK 8 25299768 25299768 single base substitution A G intron_variant ESAD-UK 8 25301225 25301225 deletion of <=200bp A - downstream_gene_variant ESAD-UK 8 25301225 25301225 deletion of <=200bp A - intron_variant ESAD-UK 8 25301388 25301388 insertion of <=200bp - T downstream_gene_variant ESAD-UK 8 25301388 25301388 insertion of <=200bp - T intron_variant ESAD-UK 8 25303636 25303636 single base substitution G C 3_prime_UTR_variant ESAD-UK 8 25303636 25303636 single base substitution G C downstream_gene_variant ESAD-UK 8 25303636 25303636 single base substitution G C intron_variant ESAD-UK 8 25304634 25304634 single base substitution G A downstream_gene_variant ESAD-UK 8 25304634 25304634 single base substitution G A intron_variant ESAD-UK 8 25304902 25304902 single base substitution C T downstream_gene_variant ESAD-UK 8 25304902 25304902 single base substitution C T intron_variant ESAD-UK 8 25305296 25305296 insertion of <=200bp - A downstream_gene_variant ESAD-UK 8 25305296 25305296 insertion of <=200bp - A intron_variant ESAD-UK 8 25307361 25307361 single base substitution A C downstream_gene_variant ESAD-UK 8 25307361 25307361 single base substitution A C intron_variant ESAD-UK 8 25311370 25311370 single base substitution T G intron_variant ESAD-UK 8 25311370 25311370 single base substitution T G upstream_gene_variant ESAD-UK 8 25312002 25312002 single base substitution G A intron_variant ESAD-UK 8 25312002 25312002 single base substitution G A upstream_gene_variant ESAD-UK 8 25316333 25316333 single base substitution A G upstream_gene_variant ESAD-UK 8 25320037 25320037 single base substitution G T upstream_gene_variant ESAD-UK 8 25320444 25320444 single base substitution C G upstream_gene_variant ESCA-CN 8 25287417 25287417 single base substitution C G 3_prime_UTR_variant ESCA-CN 8 25287417 25287417 single base substitution C G missense_variant E376Q 1126G>C ESCA-CN 8 25315700 25315700 single base substitution T C intron_variant ESCA-CN 8 25315700 25315700 single base substitution T C upstream_gene_variant GACA-CN 8 25319624 25319624 single base substitution G A upstream_gene_variant GBM-US 8 25287394 25287394 single base substitution G A 3_prime_UTR_variant GBM-US 8 25287394 25287394 single base substitution G A synonymous_variant H383H 1149C>T GBM-US 8 25319665 25319665 single base substitution C T upstream_gene_variant KIRP-US 8 25293942 25293942 single base substitution C T 3_prime_UTR_variant KIRP-US 8 25293942 25293942 single base substitution C T downstream_gene_variant KIRP-US 8 25293942 25293942 single base substitution C T exon_variant KIRP-US 8 25293942 25293942 single base substitution C T missense_variant A187T 559G>A LAML-KR 8 25280609 25280609 single base substitution C T downstream_gene_variant LICA-FR 8 25285218 25285218 single base substitution A T downstream_gene_variant LICA-FR 8 25291059 25291059 single base substitution A G downstream_gene_variant LICA-FR 8 25291059 25291059 single base substitution A G intron_variant LIHC-US 8 25319603 25319603 single base substitution G T upstream_gene_variant LINC-JP 8 25283776 25283776 single base substitution G A downstream_gene_variant LINC-JP 8 25290245 25290245 single base substitution T C downstream_gene_variant LINC-JP 8 25290245 25290245 single base substitution T C intron_variant LINC-JP 8 25290289 25290289 single base substitution T C downstream_gene_variant LINC-JP 8 25290289 25290289 single base substitution T C intron_variant LINC-JP 8 25292500 25292500 single base substitution G A downstream_gene_variant LINC-JP 8 25292500 25292500 single base substitution G A intron_variant LINC-JP 8 25301943 25301943 single base substitution T C downstream_gene_variant LINC-JP 8 25301943 25301943 single base substitution T C intron_variant LINC-JP 8 25309205 25309205 single base substitution G A intron_variant LINC-JP 8 25309205 25309205 single base substitution G A upstream_gene_variant LINC-JP 8 25316258 25316258 single base substitution T C upstream_gene_variant LINC-JP 8 25318254 25318254 single base substitution C T upstream_gene_variant LINC-JP 8 25319535 25319535 single base substitution G T upstream_gene_variant LIRI-JP 8 25281451 25281451 single base substitution T G downstream_gene_variant LIRI-JP 8 25281674 25281674 single base substitution A G downstream_gene_variant LIRI-JP 8 25282593 25282593 single base substitution T A downstream_gene_variant LIRI-JP 8 25284229 25284229 single base substitution G A downstream_gene_variant LIRI-JP 8 25285176 25285176 single base substitution T G downstream_gene_variant LIRI-JP 8 25286308 25286308 single base substitution T G 3_prime_UTR_variant LIRI-JP 8 25286308 25286308 single base substitution T G downstream_gene_variant LIRI-JP 8 25287005 25287005 single base substitution A T 3_prime_UTR_variant LIRI-JP 8 25287729 25287729 single base substitution T C intron_variant LIRI-JP 8 25289956 25289956 single base substitution A C downstream_gene_variant LIRI-JP 8 25289956 25289956 single base substitution A C intron_variant LIRI-JP 8 25291019 25291019 single base substitution A G downstream_gene_variant LIRI-JP 8 25291019 25291019 single base substitution A G intron_variant LIRI-JP 8 25291298 25291298 single base substitution T G downstream_gene_variant LIRI-JP 8 25291298 25291298 single base substitution T G intron_variant LIRI-JP 8 25292008 25292008 single base substitution A G downstream_gene_variant LIRI-JP 8 25292008 25292008 single base substitution A G intron_variant LIRI-JP 8 25292461 25292461 insertion of <=200bp - C downstream_gene_variant LIRI-JP 8 25292461 25292461 insertion of <=200bp - C intron_variant LIRI-JP 8 25296806 25296806 single base substitution A C 3_prime_UTR_variant LIRI-JP 8 25296806 25296806 single base substitution A C downstream_gene_variant LIRI-JP 8 25296806 25296806 single base substitution A C exon_variant LIRI-JP 8 25296806 25296806 single base substitution A C missense_variant I163S 488T>G LIRI-JP 8 25299516 25299516 single base substitution T C downstream_gene_variant LIRI-JP 8 25299516 25299516 single base substitution T C intron_variant LIRI-JP 8 25300522 25300522 single base substitution A T downstream_gene_variant LIRI-JP 8 25300522 25300522 single base substitution A T intron_variant LIRI-JP 8 25302122 25302122 single base substitution T G downstream_gene_variant LIRI-JP 8 25302122 25302122 single base substitution T G intron_variant LIRI-JP 8 25311770 25311770 single base substitution C T intron_variant LIRI-JP 8 25311770 25311770 single base substitution C T upstream_gene_variant LIRI-JP 8 25313717 25313717 single base substitution T C intron_variant LIRI-JP 8 25314901 25314901 single base substitution A T exon_variant LIRI-JP 8 25314901 25314901 single base substitution A T intron_variant LIRI-JP 8 25315021 25315021 single base substitution A C exon_variant LIRI-JP 8 25315021 25315021 single base substitution A C intron_variant LIRI-JP 8 25315021 25315021 single base substitution A C upstream_gene_variant LIRI-JP 8 25317723 25317723 single base substitution G A upstream_gene_variant LIRI-JP 8 25318630 25318630 single base substitution A G upstream_gene_variant LIRI-JP 8 25318997 25318997 single base substitution A G upstream_gene_variant LIRI-JP 8 25319493 25319493 single base substitution G A upstream_gene_variant LIRI-JP 8 25319793 25319793 single base substitution T C upstream_gene_variant LIRI-JP 8 25320382 25320382 single base substitution A T upstream_gene_variant LIRI-JP 8 25320595 25320595 single base substitution G A upstream_gene_variant LUSC-KR 8 25280800 25280800 single base substitution C G downstream_gene_variant LUSC-KR 8 25284665 25284665 single base substitution G T downstream_gene_variant LUSC-KR 8 25286386 25286386 single base substitution C G 3_prime_UTR_variant LUSC-KR 8 25286386 25286386 single base substitution C G downstream_gene_variant LUSC-KR 8 25286855 25286855 single base substitution G C 3_prime_UTR_variant LUSC-KR 8 25289355 25289355 single base substitution G C downstream_gene_variant LUSC-KR 8 25289355 25289355 single base substitution G C intron_variant LUSC-KR 8 25289899 25289899 single base substitution C T downstream_gene_variant LUSC-KR 8 25289899 25289899 single base substitution C T intron_variant LUSC-KR 8 25296073 25296073 single base substitution G C downstream_gene_variant LUSC-KR 8 25296073 25296073 single base substitution G C intron_variant LUSC-KR 8 25303650 25303650 single base substitution C G downstream_gene_variant LUSC-KR 8 25303650 25303650 single base substitution C G exon_variant LUSC-KR 8 25303650 25303650 single base substitution C G intron_variant LUSC-KR 8 25303650 25303650 single base substitution C G missense_variant L55F 165G>C LUSC-KR 8 25308748 25308748 single base substitution A T intron_variant LUSC-KR 8 25308748 25308748 single base substitution A T upstream_gene_variant LUSC-KR 8 25308971 25308971 single base substitution C A intron_variant LUSC-KR 8 25308971 25308971 single base substitution C A upstream_gene_variant LUSC-KR 8 25309482 25309482 single base substitution C A intron_variant LUSC-KR 8 25309482 25309482 single base substitution C A upstream_gene_variant LUSC-KR 8 25316078 25316078 single base substitution G C upstream_gene_variant LUSC-KR 8 25316089 25316089 single base substitution G T upstream_gene_variant LUSC-KR 8 25320154 25320154 single base substitution T A upstream_gene_variant LUSC-US 8 25293004 25293004 single base substitution G C 3_prime_UTR_variant LUSC-US 8 25293004 25293004 single base substitution G C downstream_gene_variant LUSC-US 8 25293004 25293004 single base substitution G C missense_variant L230V 688C>G LUSC-US 8 25296837 25296837 single base substitution G A 3_prime_UTR_variant LUSC-US 8 25296837 25296837 single base substitution G A downstream_gene_variant LUSC-US 8 25296837 25296837 single base substitution G A exon_variant LUSC-US 8 25296837 25296837 single base substitution G A missense_variant R153C 457C>T LUSC-US 8 25303650 25303650 single base substitution C G downstream_gene_variant LUSC-US 8 25303650 25303650 single base substitution C G exon_variant LUSC-US 8 25303650 25303650 single base substitution C G intron_variant LUSC-US 8 25303650 25303650 single base substitution C G missense_variant L55F 165G>C LUSC-US 8 25303661 25303661 single base substitution C T downstream_gene_variant LUSC-US 8 25303661 25303661 single base substitution C T exon_variant LUSC-US 8 25303661 25303661 single base substitution C T intron_variant LUSC-US 8 25303661 25303661 single base substitution C T missense_variant D52N 154G>A LUSC-US 8 25315739 25315739 single base substitution C T exon_variant LUSC-US 8 25315739 25315739 single base substitution C T synonymous_variant L8L 24G>A LUSC-US 8 25315739 25315739 single base substitution C T upstream_gene_variant LUSC-US 8 25317909 25317909 single base substitution C G upstream_gene_variant MALY-DE 8 25286628 25286628 single base substitution C T 3_prime_UTR_variant MALY-DE 8 25286628 25286628 single base substitution C T downstream_gene_variant MALY-DE 8 25293367 25293367 single base substitution A C downstream_gene_variant MALY-DE 8 25293367 25293367 single base substitution A C intron_variant MALY-DE 8 25301244 25301244 single base substitution A G downstream_gene_variant MALY-DE 8 25301244 25301244 single base substitution A G intron_variant MALY-DE 8 25303548 25303548 single base substitution T C downstream_gene_variant MALY-DE 8 25303548 25303548 single base substitution T C intron_variant MALY-DE 8 25305831 25305831 single base substitution C T downstream_gene_variant MALY-DE 8 25305831 25305831 single base substitution C T intron_variant MALY-DE 8 25310229 25310229 single base substitution A C intron_variant MALY-DE 8 25310229 25310229 single base substitution A C upstream_gene_variant MALY-DE 8 25313730 25313730 single base substitution G T intron_variant MALY-DE 8 25320708 25320708 single base substitution A G upstream_gene_variant MELA-AU 8 25282850 25282850 single base substitution G A downstream_gene_variant MELA-AU 8 25283747 25283747 single base substitution T C downstream_gene_variant MELA-AU 8 25283769 25283769 single base substitution A C downstream_gene_variant MELA-AU 8 25286103 25286103 single base substitution G A 3_prime_UTR_variant MELA-AU 8 25286103 25286103 single base substitution G A downstream_gene_variant MELA-AU 8 25286871 25286871 single base substitution G A 3_prime_UTR_variant MELA-AU 8 25287117 25287117 single base substitution T C 3_prime_UTR_variant MELA-AU 8 25288480 25288480 single base substitution G T downstream_gene_variant MELA-AU 8 25288480 25288480 single base substitution G T intron_variant MELA-AU 8 25288972 25288972 single base substitution G A downstream_gene_variant MELA-AU 8 25288972 25288972 single base substitution G A intron_variant MELA-AU 8 25289083 25289083 single base substitution G A downstream_gene_variant MELA-AU 8 25289083 25289083 single base substitution G A intron_variant MELA-AU 8 25289678 25289678 single base substitution T A downstream_gene_variant MELA-AU 8 25289678 25289678 single base substitution T A intron_variant MELA-AU 8 25290094 25290094 single base substitution C T 3_prime_UTR_variant MELA-AU 8 25290094 25290094 single base substitution C T downstream_gene_variant MELA-AU 8 25290094 25290094 single base substitution C T missense_variant V327M 979G>A MELA-AU 8 25291127 25291127 single base substitution G A downstream_gene_variant MELA-AU 8 25291127 25291127 single base substitution G A intron_variant MELA-AU 8 25291388 25291388 single base substitution G A downstream_gene_variant MELA-AU 8 25291388 25291388 single base substitution G A intron_variant MELA-AU 8 25291416 25291416 single base substitution A T downstream_gene_variant MELA-AU 8 25291416 25291416 single base substitution A T intron_variant MELA-AU 8 25291664 25291664 single base substitution G A downstream_gene_variant MELA-AU 8 25291664 25291664 single base substitution G A intron_variant MELA-AU 8 25291836 25291836 single base substitution G A downstream_gene_variant MELA-AU 8 25291836 25291836 single base substitution G A intron_variant MELA-AU 8 25293359 25293359 single base substitution A T downstream_gene_variant MELA-AU 8 25293359 25293359 single base substitution A T intron_variant MELA-AU 8 25298166 25298166 single base substitution G A 3_prime_UTR_variant MELA-AU 8 25298166 25298166 single base substitution G A exon_variant MELA-AU 8 25298166 25298166 single base substitution G A missense_variant P80S 238C>T MELA-AU 8 25298580 25298580 single base substitution G A intron_variant MELA-AU 8 25298619 25298619 single base substitution C G intron_variant MELA-AU 8 25298988 25298988 single base substitution A T downstream_gene_variant MELA-AU 8 25298988 25298988 single base substitution A T intron_variant MELA-AU 8 25299004 25299004 single base substitution C T downstream_gene_variant MELA-AU 8 25299004 25299004 single base substitution C T intron_variant MELA-AU 8 25299077 25299077 single base substitution G T downstream_gene_variant MELA-AU 8 25299077 25299077 single base substitution G T intron_variant MELA-AU 8 25299302 25299302 single base substitution G A downstream_gene_variant MELA-AU 8 25299302 25299302 single base substitution G A intron_variant MELA-AU 8 25300517 25300517 single base substitution A C downstream_gene_variant MELA-AU 8 25300517 25300517 single base substitution A C intron_variant MELA-AU 8 25302242 25302242 single base substitution G A downstream_gene_variant MELA-AU 8 25302242 25302242 single base substitution G A intron_variant MELA-AU 8 25302279 25302279 single base substitution C T downstream_gene_variant MELA-AU 8 25302279 25302279 single base substitution C T intron_variant MELA-AU 8 25302572 25302572 single base substitution G A downstream_gene_variant MELA-AU 8 25302572 25302572 single base substitution G A intron_variant MELA-AU 8 25303372 25303391 deletion of <=200bp AGATCCTTCTCTAGTACCAC - downstream_gene_variant MELA-AU 8 25303372 25303391 deletion of <=200bp AGATCCTTCTCTAGTACCAC - intron_variant MELA-AU 8 25303508 25303508 single base substitution C A downstream_gene_variant MELA-AU 8 25303508 25303508 single base substitution C A intron_variant MELA-AU 8 25305647 25305647 single base substitution G A downstream_gene_variant MELA-AU 8 25305647 25305647 single base substitution G A intron_variant MELA-AU 8 25306585 25306585 single base substitution C A downstream_gene_variant MELA-AU 8 25306585 25306585 single base substitution C A intron_variant MELA-AU 8 25307000 25307000 single base substitution A G downstream_gene_variant MELA-AU 8 25307000 25307000 single base substitution A G intron_variant MELA-AU 8 25307613 25307613 single base substitution G A downstream_gene_variant MELA-AU 8 25307613 25307613 single base substitution G A intron_variant MELA-AU 8 25308244 25308245 multiple base substitution (>=2bp and <=200bp) GT AA intron_variant MELA-AU 8 25308244 25308245 multiple base substitution (>=2bp and <=200bp) GT AA upstream_gene_variant MELA-AU 8 25308375 25308375 single base substitution G A intron_variant MELA-AU 8 25308375 25308375 single base substitution G A upstream_gene_variant MELA-AU 8 25308511 25308511 single base substitution G A intron_variant MELA-AU 8 25308511 25308511 single base substitution G A upstream_gene_variant MELA-AU 8 25308742 25308742 single base substitution T C intron_variant MELA-AU 8 25308742 25308742 single base substitution T C upstream_gene_variant MELA-AU 8 25309863 25309863 single base substitution A G intron_variant MELA-AU 8 25309863 25309863 single base substitution A G upstream_gene_variant MELA-AU 8 25311474 25311474 single base substitution G T intron_variant MELA-AU 8 25311474 25311474 single base substitution G T upstream_gene_variant MELA-AU 8 25311737 25311737 single base substitution G A intron_variant MELA-AU 8 25311737 25311737 single base substitution G A upstream_gene_variant MELA-AU 8 25312931 25312931 single base substitution G A intron_variant MELA-AU 8 25312931 25312931 single base substitution G A upstream_gene_variant MELA-AU 8 25314661 25314661 single base substitution G A intron_variant MELA-AU 8 25315749 25315749 single base substitution G A exon_variant MELA-AU 8 25315749 25315749 single base substitution G A missense_variant T5I 14C>T MELA-AU 8 25315749 25315749 single base substitution G A upstream_gene_variant MELA-AU 8 25315995 25315995 single base substitution C T upstream_gene_variant MELA-AU 8 25316279 25316279 single base substitution T C upstream_gene_variant MELA-AU 8 25316286 25316286 single base substitution G A upstream_gene_variant MELA-AU 8 25316405 25316405 single base substitution G A upstream_gene_variant MELA-AU 8 25316450 25316450 single base substitution A T upstream_gene_variant MELA-AU 8 25316457 25316457 single base substitution G A upstream_gene_variant MELA-AU 8 25316459 25316459 single base substitution G A upstream_gene_variant MELA-AU 8 25316553 25316553 single base substitution C T upstream_gene_variant MELA-AU 8 25317056 25317056 single base substitution T C upstream_gene_variant MELA-AU 8 25317875 25317875 single base substitution C T upstream_gene_variant MELA-AU 8 25318482 25318482 single base substitution C T upstream_gene_variant MELA-AU 8 25318709 25318710 multiple base substitution (>=2bp and <=200bp) GG AA upstream_gene_variant MELA-AU 8 25318751 25318751 single base substitution C T upstream_gene_variant MELA-AU 8 25318842 25318842 single base substitution C T upstream_gene_variant MELA-AU 8 25319144 25319144 single base substitution C T upstream_gene_variant MELA-AU 8 25319940 25319940 single base substitution C T upstream_gene_variant MELA-AU 8 25320268 25320268 single base substitution C T upstream_gene_variant MELA-AU 8 25320523 25320523 single base substitution G A upstream_gene_variant ORCA-IN 8 25284146 25284146 single base substitution T C downstream_gene_variant ORCA-IN 8 25288279 25288279 single base substitution G A downstream_gene_variant ORCA-IN 8 25288279 25288279 single base substitution G A intron_variant ORCA-IN 8 25290091 25290091 single base substitution C T 3_prime_UTR_variant ORCA-IN 8 25290091 25290091 single base substitution C T downstream_gene_variant ORCA-IN 8 25290091 25290091 single base substitution C T missense_variant A328T 982G>A ORCA-IN 8 25302560 25302560 single base substitution G C downstream_gene_variant ORCA-IN 8 25302560 25302560 single base substitution G C intron_variant OV-AU 8 25295147 25295147 single base substitution T G downstream_gene_variant OV-AU 8 25295147 25295147 single base substitution T G intron_variant OV-AU 8 25307527 25307527 single base substitution A G downstream_gene_variant OV-AU 8 25307527 25307527 single base substitution A G intron_variant OV-AU 8 25307597 25307597 single base substitution G C downstream_gene_variant OV-AU 8 25307597 25307597 single base substitution G C intron_variant OV-AU 8 25314291 25314291 single base substitution G C intron_variant PACA-AU 8 25282327 25282327 single base substitution C T downstream_gene_variant PACA-AU 8 25283391 25283391 insertion of <=200bp - A downstream_gene_variant PACA-AU 8 25286272 25286272 deletion of <=200bp T - 3_prime_UTR_variant PACA-AU 8 25286272 25286272 deletion of <=200bp T - downstream_gene_variant PACA-AU 8 25306026 25306026 deletion of <=200bp A - downstream_gene_variant PACA-AU 8 25306026 25306026 deletion of <=200bp A - intron_variant PACA-AU 8 25306276 25306276 deletion of <=200bp A - downstream_gene_variant PACA-AU 8 25306276 25306276 deletion of <=200bp A - intron_variant PACA-AU 8 25306445 25306445 single base substitution A G downstream_gene_variant PACA-AU 8 25306445 25306445 single base substitution A G intron_variant PACA-AU 8 25306902 25306902 single base substitution C T downstream_gene_variant PACA-AU 8 25306902 25306902 single base substitution C T intron_variant PACA-AU 8 25312856 25312856 single base substitution T C intron_variant PACA-AU 8 25312856 25312856 single base substitution T C upstream_gene_variant PACA-AU 8 25314338 25314338 single base substitution C A intron_variant PACA-CA 8 25283590 25283590 single base substitution C G downstream_gene_variant PACA-CA 8 25296230 25296230 single base substitution A C downstream_gene_variant PACA-CA 8 25296230 25296230 single base substitution A C intron_variant PACA-CA 8 25296233 25296233 single base substitution C T downstream_gene_variant PACA-CA 8 25296233 25296233 single base substitution C T intron_variant PACA-CA 8 25297107 25297119 deletion of <=200bp ACGTGTTACACTC - downstream_gene_variant PACA-CA 8 25297107 25297119 deletion of <=200bp ACGTGTTACACTC - splice_region_variant PACA-CA 8 25297856 25297856 single base substitution G A downstream_gene_variant PACA-CA 8 25297856 25297856 single base substitution G A intron_variant PACA-CA 8 25300602 25300602 single base substitution A G downstream_gene_variant PACA-CA 8 25300602 25300602 single base substitution A G intron_variant PACA-CA 8 25308429 25308429 single base substitution T C intron_variant PACA-CA 8 25308429 25308429 single base substitution T C upstream_gene_variant PACA-CA 8 25310736 25310736 single base substitution G C intron_variant PACA-CA 8 25310736 25310736 single base substitution G C upstream_gene_variant PACA-CA 8 25314392 25314392 single base substitution G T intron_variant PAEN-AU 8 25281207 25281207 single base substitution A G downstream_gene_variant PAEN-AU 8 25308280 25308280 single base substitution T C intron_variant PAEN-AU 8 25308280 25308280 single base substitution T C upstream_gene_variant PAEN-AU 8 25310902 25310902 single base substitution T G intron_variant PAEN-AU 8 25310902 25310902 single base substitution T G upstream_gene_variant PAEN-IT 8 25286691 25286691 single base substitution G T 3_prime_UTR_variant PAEN-IT 8 25286691 25286691 single base substitution G T downstream_gene_variant PAEN-IT 8 25292466 25292466 single base substitution G A downstream_gene_variant PAEN-IT 8 25292466 25292466 single base substitution G A intron_variant PAEN-IT 8 25316333 25316333 single base substitution A C upstream_gene_variant PBCA-DE 8 25282150 25282150 single base substitution G A downstream_gene_variant PBCA-DE 8 25297195 25297195 insertion of <=200bp - A 3_prime_UTR_variant PBCA-DE 8 25297195 25297195 insertion of <=200bp - A downstream_gene_variant PBCA-DE 8 25297195 25297195 insertion of <=200bp - A exon_variant PBCA-DE 8 25297195 25297195 insertion of <=200bp - A intron_variant PBCA-DE 8 25307337 25307337 deletion of <=200bp A - downstream_gene_variant PBCA-DE 8 25307337 25307337 deletion of <=200bp A - intron_variant PRAD-UK 8 25283159 25283159 deletion of <=200bp A - downstream_gene_variant PRAD-UK 8 25290538 25290538 single base substitution T A downstream_gene_variant PRAD-UK 8 25290538 25290538 single base substitution T A intron_variant PRAD-UK 8 25304336 25304336 single base substitution T G downstream_gene_variant PRAD-UK 8 25304336 25304336 single base substitution T G intron_variant PRAD-UK 8 25313119 25313119 single base substitution T C intron_variant PRAD-UK 8 25313119 25313119 single base substitution T C upstream_gene_variant RECA-EU 8 25281678 25281678 single base substitution A G downstream_gene_variant RECA-EU 8 25287728 25287728 single base substitution A C intron_variant RECA-EU 8 25289610 25289610 single base substitution T G downstream_gene_variant RECA-EU 8 25289610 25289610 single base substitution T G intron_variant RECA-EU 8 25316551 25316551 single base substitution T A upstream_gene_variant SKCA-BR 8 25281278 25281278 single base substitution A G downstream_gene_variant SKCA-BR 8 25281575 25281575 single base substitution C T downstream_gene_variant SKCA-BR 8 25288011 25288011 single base substitution C T downstream_gene_variant SKCA-BR 8 25288011 25288011 single base substitution C T intron_variant SKCA-BR 8 25301759 25301759 insertion of <=200bp - CT downstream_gene_variant SKCA-BR 8 25301759 25301759 insertion of <=200bp - CT intron_variant SKCA-BR 8 25302927 25302927 single base substitution G A downstream_gene_variant SKCA-BR 8 25302927 25302927 single base substitution G A intron_variant SKCA-BR 8 25304429 25304429 single base substitution G C downstream_gene_variant SKCA-BR 8 25304429 25304429 single base substitution G C intron_variant SKCA-BR 8 25305417 25305417 single base substitution T G downstream_gene_variant SKCA-BR 8 25305417 25305417 single base substitution T G intron_variant SKCA-BR 8 25305420 25305420 single base substitution A G downstream_gene_variant SKCA-BR 8 25305420 25305420 single base substitution A G intron_variant SKCA-BR 8 25306520 25306520 single base substitution C T downstream_gene_variant SKCA-BR 8 25306520 25306520 single base substitution C T intron_variant SKCA-BR 8 25306961 25306961 single base substitution A C downstream_gene_variant SKCA-BR 8 25306961 25306961 single base substitution A C intron_variant SKCA-BR 8 25308198 25308198 single base substitution C G intron_variant SKCA-BR 8 25308198 25308198 single base substitution C G upstream_gene_variant SKCA-BR 8 25308449 25308449 single base substitution G A intron_variant SKCA-BR 8 25308449 25308449 single base substitution G A upstream_gene_variant SKCA-BR 8 25308603 25308603 single base substitution G A intron_variant SKCA-BR 8 25308603 25308603 single base substitution G A upstream_gene_variant SKCA-BR 8 25311051 25311051 single base substitution C T intron_variant SKCA-BR 8 25311051 25311051 single base substitution C T upstream_gene_variant SKCA-BR 8 25311052 25311052 single base substitution C T intron_variant SKCA-BR 8 25311052 25311052 single base substitution C T upstream_gene_variant SKCA-BR 8 25311354 25311354 single base substitution C T intron_variant SKCA-BR 8 25311354 25311354 single base substitution C T upstream_gene_variant SKCA-BR 8 25315108 25315108 single base substitution A G exon_variant SKCA-BR 8 25315108 25315108 single base substitution A G intron_variant SKCA-BR 8 25315108 25315108 single base substitution A G upstream_gene_variant SKCA-BR 8 25316789 25316789 single base substitution A G upstream_gene_variant SKCA-BR 8 25318882 25318882 single base substitution G A upstream_gene_variant SKCA-BR 8 25319635 25319635 single base substitution G A upstream_gene_variant SKCM-US 8 25287476 25287476 single base substitution G A 3_prime_UTR_variant SKCM-US 8 25287476 25287476 single base substitution G A missense_variant S356F 1067C>T SKCM-US 8 25296851 25296851 single base substitution A G 3_prime_UTR_variant SKCM-US 8 25296851 25296851 single base substitution A G downstream_gene_variant SKCM-US 8 25296851 25296851 single base substitution A G exon_variant SKCM-US 8 25296851 25296851 single base substitution A G missense_variant I148T 443T>C SKCM-US 8 25298174 25298174 single base substitution G A 3_prime_UTR_variant SKCM-US 8 25298174 25298174 single base substitution G A exon_variant SKCM-US 8 25298174 25298174 single base substitution G A missense_variant S77F 230C>T STAD-US 8 25280721 25280721 single base substitution A G downstream_gene_variant STAD-US 8 25280807 25280807 single base substitution G T downstream_gene_variant STAD-US 8 25287389 25287389 single base substitution G C 3_prime_UTR_variant STAD-US 8 25287389 25287389 single base substitution G C stop_gained S385* 1154C>G STAD-US 8 25287444 25287445 deletion of <=200bp CT - 3_prime_UTR_variant STAD-US 8 25287444 25287445 deletion of <=200bp CT - frameshift_variant RG366 STAD-US 8 25287452 25287452 single base substitution T C 3_prime_UTR_variant STAD-US 8 25287452 25287452 single base substitution T C missense_variant N364S 1091A>G STAD-US 8 25290076 25290076 single base substitution C G 3_prime_UTR_variant STAD-US 8 25290076 25290076 single base substitution C G downstream_gene_variant STAD-US 8 25290076 25290076 single base substitution C G missense_variant A333P 997G>C STAD-US 8 25290099 25290099 single base substitution A G 3_prime_UTR_variant STAD-US 8 25290099 25290099 single base substitution A G downstream_gene_variant STAD-US 8 25290099 25290099 single base substitution A G missense_variant L325P 974T>C STAD-US 8 25292919 25292919 single base substitution G A 3_prime_UTR_variant STAD-US 8 25292919 25292919 single base substitution G A downstream_gene_variant STAD-US 8 25292919 25292919 single base substitution G A missense_variant A258V 773C>T STAD-US 8 25293788 25293788 deletion of <=200bp A - 3_prime_UTR_variant STAD-US 8 25293788 25293788 deletion of <=200bp A - downstream_gene_variant STAD-US 8 25293788 25293788 deletion of <=200bp A - exon_variant STAD-US 8 25293788 25293788 deletion of <=200bp A - frameshift_variant L209 STAD-US 8 25293964 25293964 single base substitution T C 3_prime_UTR_variant STAD-US 8 25293964 25293964 single base substitution T C downstream_gene_variant STAD-US 8 25293964 25293964 single base substitution T C exon_variant STAD-US 8 25293964 25293964 single base substitution T C synonymous_variant S179S 537A>G STAD-US 8 25296817 25296817 single base substitution T C 3_prime_UTR_variant STAD-US 8 25296817 25296817 single base substitution T C downstream_gene_variant STAD-US 8 25296817 25296817 single base substitution T C exon_variant STAD-US 8 25296817 25296817 single base substitution T C synonymous_variant V159V 477A>G STAD-US 8 25296837 25296837 single base substitution G A 3_prime_UTR_variant STAD-US 8 25296837 25296837 single base substitution G A downstream_gene_variant STAD-US 8 25296837 25296837 single base substitution G A exon_variant STAD-US 8 25296837 25296837 single base substitution G A missense_variant R153C 457C>T STAD-US 8 25301820 25301820 single base substitution C G downstream_gene_variant STAD-US 8 25301820 25301820 single base substitution C G exon_variant STAD-US 8 25301820 25301820 single base substitution C G intron_variant STAD-US 8 25301820 25301820 single base substitution C G missense_variant E68Q 202G>C STAD-US 8 25317936 25317936 single base substitution T C upstream_gene_variant THCA-SA 8 25280800 25280800 single base substitution C G downstream_gene_variant THCA-SA 8 25287397 25287397 single base substitution T C 3_prime_UTR_variant THCA-SA 8 25287397 25287397 single base substitution T C synonymous_variant L382L 1146A>G THCA-SA 8 25315837 25315837 single base substitution G A 5_prime_UTR_variant THCA-SA 8 25315837 25315837 single base substitution G A exon_variant THCA-SA 8 25315837 25315837 single base substitution G A upstream_gene_variant THCA-SA 8 25316661 25316661 single base substitution G T upstream_gene_variant THCA-SA 8 25316789 25316789 single base substitution A G upstream_gene_variant UCEC-US 8 25290916 25290916 single base substitution A C 3_prime_UTR_variant UCEC-US 8 25290916 25290916 single base substitution A C downstream_gene_variant UCEC-US 8 25290916 25290916 single base substitution A C synonymous_variant S283S 849T>G UCEC-US 8 25290947 25290947 single base substitution G A 3_prime_UTR_variant UCEC-US 8 25290947 25290947 single base substitution G A downstream_gene_variant UCEC-US 8 25290947 25290947 single base substitution G A missense_variant A273V 818C>T UCEC-US 8 25292998 25292998 single base substitution G A 3_prime_UTR_variant UCEC-US 8 25292998 25292998 single base substitution G A downstream_gene_variant UCEC-US 8 25292998 25292998 single base substitution G A missense_variant R232C 694C>T UCEC-US 8 25293759 25293759 single base substitution G A 3_prime_UTR_variant UCEC-US 8 25293759 25293759 single base substitution G A downstream_gene_variant UCEC-US 8 25293759 25293759 single base substitution G A stop_gained R219* 655C>T UCEC-US 8 25293979 25293979 single base substitution A C 3_prime_UTR_variant UCEC-US 8 25293979 25293979 single base substitution A C downstream_gene_variant UCEC-US 8 25293979 25293979 single base substitution A C exon_variant UCEC-US 8 25293979 25293979 single base substitution A C missense_variant F174L 522T>G UCEC-US 8 25296809 25296809 single base substitution C T 3_prime_UTR_variant UCEC-US 8 25296809 25296809 single base substitution C T downstream_gene_variant UCEC-US 8 25296809 25296809 single base substitution C T exon_variant UCEC-US 8 25296809 25296809 single base substitution C T missense_variant G162D 485G>A UCEC-US 8 25318047 25318047 single base substitution A G upstream_gene_variant UCEC-US 8 25319576 25319576 single base substitution C A upstream_gene_variant UCEC-US 8 25319579 25319579 single base substitution C T upstream_gene_variant UCEC-US 8 25319665 25319665 single base substitution C T upstream_gene_variant UCEC-US 8 25319714 25319714 single base substitution C A upstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-FW-A5DX-01 COSM3647608 c.1067C>T p.S356F Substitution - Missense 8:25429960-25429960 - PTC-7C COSM2787238 c.1107C>T p.N369N Substitution - coding silent 8:25429920-25429920 - TCGA-BQ-5892-01 COSM3995988 c.559G>A p.A187T Substitution - Missense 8:25436426-25436426 - CDGLIV0709A0255_T COSM5038798 c.151_152insT p.D51fs*2 Insertion - Frameshift 8:25446147-25446148 - 255 COSM3732132 c.1072T>C p.C358R Substitution - Missense 8:25429955-25429955 - TCGA-WS-AB45-01 COSM5152862 c.292C>T p.R98W Substitution - Missense 8:25440596-25440596 - TCGA-CG-5721-01 COSM3899115 c.1091A>G p.N364S Substitution - Missense 8:25429936-25429936 - TCGA-AP-A0LM-01 COSM1098457 c.818C>T p.A273V Substitution - Missense 8:25433431-25433431 - LUAD-CHTN-MAD04-00674 COSM357909 c.333A>C p.E111D Substitution - Missense 8:25439643-25439643 - ccRCC-43 COSM1662401 c.401G>A p.G134E Substitution - Missense 8:25439377-25439377 - TCGA-AP-A052-01 COSM1098462 c.368A>T p.K123I Substitution - Missense 8:25439608-25439608 - LUAD-5V8LT COSM402980 c.343A>G p.M115V Substitution - Missense 8:25439633-25439633 - EGC3 COSM5063053 c.458G>A p.R153H Substitution - Missense 8:25439320-25439320 - TCGA-BR-8680-01 COSM3899120 c.477A>G p.V159V Substitution - coding silent 8:25439301-25439301 - 802-01-11TD COSM5419065 c.723A>T p.K241N Substitution - Missense 8:25435453-25435453 - LOVO COSM1456268 c.995delA p.N332fs*4 Deletion - Frameshift 8:25432562-25432562 - LS180 COSM2787253 c.355A>G p.M119V Substitution - Missense 8:25439621-25439621 - TCGA-BR-8370-01 COSM3899114 c.1154C>G p.S385* Substitution - Nonsense 8:25429873-25429873 - ESCC-008T COSM3942623 c.1126G>C p.E376Q Substitution - Missense 8:25429901-25429901 - SJHGG064_A COSM4969789 c.106G>A p.G36S Substitution - Missense 8:25446193-25446193 - TCGA-AX-A0J0-01 COSM1098460 c.522T>G p.F174L Substitution - Missense 8:25436463-25436463 - TCGA-CD-8536-01 COSM3899116 c.997G>C p.A333P Substitution - Missense 8:25432560-25432560 - TCGA-A6-6781-01 COSM1456271 c.461A>G p.H154R Substitution - Missense 8:25439317-25439317 - YUGAFFE COSM1699865 c.200G>A p.G67E Substitution - Missense 8:25444306-25444306 - TCGA-CG-4305-01 COSM3899117 c.974T>C p.L325P Substitution - Missense 8:25432583-25432583 - TCGA-33-6737-01 COSM750003 c.165G>C p.L55F Substitution - Missense 8:25446134-25446134 - TCGA-D1-A177-01 COSM1098459 c.655C>T p.R219* Substitution - Nonsense 8:25436243-25436243 - CAL27 COSM2787242 c.883T>G p.F295V Substitution - Missense 8:25433366-25433366 - TCGA-AD-A5EJ-01 COSM5134017 c.304A>G p.T102A Substitution - Missense 8:25440584-25440584 - TCGA-BR-6452-01 COSM3899119 c.537A>G p.S179S Substitution - coding silent 8:25436448-25436448 - 970010 COSM1582756 c.311+5G>A p.? Unknown 8:25440572-25440572 - RK027_C01 COSM1635732 c.488T>G p.I163S Substitution - Missense 8:25439290-25439290 - TCGA-G4-6628-01 COSM1456272 c.199G>T p.G67* Substitution - Nonsense 8:25444307-25444307 - C086 COSM5533153 c.641C>T p.T214I Substitution - Missense 8:25436257-25436257 - TCGA-AX-A0J0-01 COSM1098456 c.849T>G p.S283S Substitution - coding silent 8:25433400-25433400 - SA106 COSM213798 c.74C>G p.S25C Substitution - Missense 8:25446225-25446225 - TCGA-AD-5900-01 COSM1456268 c.995delA p.N332fs*4 Deletion - Frameshift 8:25432562-25432562 - STC252 COSM5063054 c.438A>G p.E146E Substitution - coding silent 8:25439340-25439340 - TCGA-19-2629-01 COSM3412947 c.1149C>T p.H383H Substitution - coding silent 8:25429878-25429878 - BD72T COSM1456268 c.995delA p.N332fs*4 Deletion - Frameshift 8:25432562-25432562 - PD6647a COSM3719955 c.1154C>T p.S385L Substitution - Missense 8:25429873-25429873 - TCGA-60-2722-01 COSM750001 c.24G>A p.L8L Substitution - coding silent 8:25458223-25458223 - Capan-1 COSM328227 c.986C>A p.T329N Substitution - Missense 8:25432571-25432571 - CSCC-10-T COSM4568039 c.986_987CC>TT p.T329I Substitution - Missense 8:25432570-25432571 - PD6016a2 COSM5788473 c.896C>T p.S299F Substitution - Missense 8:25433353-25433353 - TCGA-AP-A051-01 COSM1098461 c.485G>A p.G162D Substitution - Missense 8:25439293-25439293 - TCGA-CM-6162-01 COSM1456268 c.995delA p.N332fs*4 Deletion - Frameshift 8:25432562-25432562 - TCGA-HU-A4G8-01 COSM750004 c.457C>T p.R153C Substitution - Missense 8:25439321-25439321 - KM12 COSM1456268 c.995delA p.N332fs*4 Deletion - Frameshift 8:25432562-25432562 - J76_T COSM750003 c.165G>C p.L55F Substitution - Missense 8:25446134-25446134 - TCGA-BS-A0UF-01 COSM1098458 c.694C>T p.R232C Substitution - Missense 8:25435482-25435482 - TCGA-AA-A00A-01 COSM273740 c.479_480insA p.N160fs*2 Insertion - Frameshift 8:25439298-25439299 - TCGA-AM-5820-01 COSM3763275 c.1146A>G p.L382L Substitution - coding silent 8:25429881-25429881 - TCGA-FW-A3R5-06 COSM3925067 c.230C>T p.S77F Substitution - Missense 8:25440658-25440658 - TCGA-CK-4951-01 COSM5152862 c.292C>T p.R98W Substitution - Missense 8:25440596-25440596 - LIM1215 COSM1456268 c.995delA p.N332fs*4 Deletion - Frameshift 8:25432562-25432562 - TCGA-E2-A15R-01 COSM454347 c.734T>C p.L245S Substitution - Missense 8:25435442-25435442 - LUAD-F00365 COSM340820 c.1036G>C p.A346P Substitution - Missense 8:25432521-25432521 - TCGA-BR-4370-01 COSM3899116 c.997G>C p.A333P Substitution - Missense 8:25432560-25432560 - TCGA-CM-6674-01 COSM1456270 c.983C>T p.A328V Substitution - Missense 8:25432574-25432574 - LS174T COSM2787253 c.355A>G p.M119V Substitution - Missense 8:25439621-25439621 - TCGA-B0-5098-01 COSM1496839 c.939G>T p.V313V Substitution - coding silent 8:25432618-25432618 - OSCC-GB_00590111 COSM4888571 c.982G>A p.A328T Substitution - Missense 8:25432575-25432575 - ESO-0001 COSM1255474 c.1053+1G>T p.? Unknown 8:25432503-25432503 - TCGA-D7-A4YU-01 COSM3899121 c.202G>C p.E68Q Substitution - Missense 8:25444304-25444304 - TCGA-AA-3715-01 COSM1456268 c.995delA p.N332fs*4 Deletion - Frameshift 8:25432562-25432562 - P05-2594 COSM245187 c.903T>G p.L301L Substitution - coding silent 8:25433346-25433346 - PT45 COSM5927504 c.604C>T p.R202* Substitution - Nonsense 8:25436294-25436294 - pfg181T COSM4751441 c.614T>C p.F205S Substitution - Missense 8:25436284-25436284 - TCGA-33-6737-01 COSM750002 c.154G>A p.D52N Substitution - Missense 8:25446145-25446145 - I2L-P7-Tumor-Organoid COSM5359045 c.921T>C p.G307G Substitution - coding silent 8:25432636-25432636 - Pat_53_B COSM1098459 c.655C>T p.R219* Substitution - Nonsense 8:25436243-25436243 - TCGA-60-2719-01 COSM750004 c.457C>T p.R153C Substitution - Missense 8:25439321-25439321 - TCGA-HU-A4GX-01 COSM3899118 c.773C>T p.A258V Substitution - Missense 8:25435403-25435403 - 2476_CLM COSM5757192 c.267C>G p.D89E Substitution - Missense 8:25440621-25440621 - TCGA-FW-A5DX-01 COSM3647609 c.443T>C p.I148T Substitution - Missense 8:25439335-25439335 - pfg129T COSM4746810 c.1098_1099delAG p.G367fs*9 Deletion - Frameshift 8:25429928-25429929 - 66 COSM2787244 c.695G>A p.R232H Substitution - Missense 8:25435481-25435481 - CSB34 COSM5026892 c.49G>A p.V17M Substitution - Missense 8:25446250-25446250 - ESO-0280 COSM1255475 c.143G>A p.G48E Substitution - Missense 8:25446156-25446156 - TCGA-33-4547-01 COSM750005 c.688C>G p.L230V Substitution - Missense 8:25435488-25435488 - TCGA-AA-3977-01 COSM1098457 c.818C>T p.A273V Substitution - Missense 8:25433431-25433431 - TCGA-NH-A5IV-01 COSM1456268 c.995delA p.N332fs*4 Deletion - Frameshift 8:25432562-25432562 - LOVO COSM1098459 c.655C>T p.R219* Substitution - Nonsense 8:25436243-25436243 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.72071 8p21.1 Hs.188763 8p21.1

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Missense p.I163S c.488T>G 8 25296806 HC A G Missense p.L245S c.734T>C 8 25292958 BRCA A G Missense p.L325P c.974T>C 8 25290099 STAD A T 3-UTRSNV . c.1167+371T>A 8 25287005 HC C A SpliceDonorSNV . c.1053+1G>T 8 25290019 ESCA C G Missense p.A333P c.997G>C 8 25290076 STAD C G Missense p.L55F c.165G>C 8 25303650 LUSC C T 3-UTRSNV . c.1167+748G>A 8 25286628 DLBCL C T Missense p.D52N c.154G>A 8 25303661 LUSC C T Missense p.G48E c.143G>A 8 25303672 ESCA C T Missense p.S387N c.1160G>A 8 25287383 CM C T Missense p.V17M c.49G>A 8 25303766 BRCA C T Synonymous p.L8L c.24G>A 8 25315739 LUSC G A Missense p.R153C c.457C>T 8 25296837 LUSC G A Nonsense p.R219* c.655C>T 8 25293759 UCEC G A Synonymous p.H383H c.1149C>T 8 25287394 GBM G C Missense p.L230V c.688C>G 8 25293004 LUSC G C Missense p.S25C c.74C>G 8 25303741 BRCA GG AA Missense p.S368F c.1103_1104delinsTT 8 25287439 CM T C Missense p.N254S c.761A>G 8 25292931 LUAD - T Frameshift p.N160Kfs*2 c.479dupA 8 25296815 COREAD