PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CDCA3 FZR1 26186194 biogrid exp G GP G G G P G GP GP P P GP G G GP P G G G G GP GP G GP GP G LAMTOR4 CDCA3 26186194 biogrid exp G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CDCA3 CTDSP1 25416956,16189514,26186194 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G CDCA3 BCL11A 21988832 biogrid,intact exp G G G G GP P G G G G G GP P G G G GP GP GP G ATP6V1C1 CDCA3 26186194 biogrid exp G GP G G G P G GP GP P GP GP G GP P G G G GP GP G GP GP GP G G NMT1 CDCA3 26186194 biogrid exp G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G GTF2H5 CDCA3 26496610 biogrid,intact exp G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP G GP G GP GP G CTDSP2 CDCA3 25416956,21516116,26186194 biogrid,intact exp G GP G G GP P G G GP P P GP G G GP P G G G GP GP GP GP G GP GP G TRAF1 CDCA3 25416956 biogrid,intact exp G G G G GP P G G GP P G GP G G P G G G G G G GP G G G CDCA3 PARD6B 26496610 biogrid,intact exp P P P P P P GP P G GP P G GP GP P GP GP GP G CDCA3 CHORDC1 26496610 biogrid,intact exp G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP G GP GP GP GP G CTDNEP1 CDCA3 26186194 biogrid exp G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G TRAF2 CDCA3 25416956,16189514 hprd,biogrid,mint,intact exp P P P P P P P P P P P P P P P GP GP P BAG3 CDCA3 23824909 biogrid exp G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CDCA3 TMEM216 26638075 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G APP CDCA3 21832049 biogrid exp G GP G G GP P G G GP G G G GP P G G G GP G G GP G G GP G CTDSPL CDCA3 26186194 biogrid exp G G G G G P G G GP GP G G G P G G G GP G GP G G G G G PLOD1 CDCA3 22939629 biogrid exp G G G G G P G G GP P GP G G GP P G G G GP G G GP G GP G G TMEM17 CDCA3 26638075 biogrid,intact exp GP G P P G P P P P P G G P P G G P GP P P P P GP CUL1 CDCA3 12679038, 21836163 hprd,biogrid exp, pred G G G G G P G GP GP P P GP G G GP P G G G GP GP GP GP GP GP GP G WEE1 CDCA3 12679038, 21836163 hprd,biogrid exp, pred G GP G GP P G G GP GP GP G GP P G G G GP G G GP GP GP GP G SKP1 CDCA3 19159283,15070733,12679038, 25402006, 21836163 hprd,biogrid,intact exp, pred G GP G G GP P G G GP P P GP GP G GP P G G G GP GP G GP GP GP GP G FBXO17 CDCA3 25402006 pred G G G G G G G G CDC45 CDCA3 25402006 pred P P P P P P P P P G P GP CDK1 CDCA3 25402006 pred G G GP G GP P P P GP G G G GP GP GP GP GP FBXW9 CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G G GP GP GP G GP GP G ASPM CDCA3 25402006 pred P G GP P P GP P P P P P P P P P P P P GP CDCA3 FBXO5 25402006 pred P G GP P P GP P P P P GP P G P P P GP GP P P BUB1 CDCA3 25402006 pred P G GP P P GP P P P P GP P P P P P P P GP AURKA CDCA3 25402006 pred G GP P G G G GP G P G G G G G GP LMNB1 CDCA3 25402006 pred G P G GP P P GP P P GP GP G GP P G G GP P P GP GP GP P CDC20 CDCA3 25402006 pred G GP G GP P P GP G G P GP P GP GP DHFR CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G ZWINT CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CDCA3 ASF1B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G CDCA3 GTSE1 25402006 pred G G G G G P G G GP P G G G G P G G G GP G G G G G G G CENPU CDCA3 25402006 pred G GP G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CDCA3 NUF2 25402006 pred G G G FBXW8 CDCA3 25402006 pred P P P P P P P P P P P P P P P P P P H2AFZ CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G KIF14 CDCA3 25402006 pred P G GP P P GP P P P P GP P G P P P GP P GP GP MCM2 CDCA3 25402006 pred G G G G GP G G GP G GP G GP G G G GP G G GP GP GP GP G TRIP13 CDCA3 25402006 pred G G G G G G G G G G G G G G G G G G G G G GP G MKI67 CDCA3 25402006 pred G GP G G GP G G GP P G GP G GP G G G GP GP G GP GP GP GP G MCM4 CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CDCA3 NCAPG 25402006 pred G GP P GP GP P P P GP G GP P G P G G GP GP GP G CDCA3 SMC4 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G NEK2 CDCA3 25402006 pred P G G P P GP P P GP P P P P GP P P GP CDCA3 KIF2C 25402006 pred G G G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G ATAD2 CDCA3 25402006 pred P G GP P G P P P P P G P P P P P GP CDCA3 MND1 25402006 pred P G G P P P P P P P P P G P P P P P GP CCNA2 CDCA3 25402006 pred G G G G GP G G GP G GP G GP G G G G G GP GP GP GP FOXM1 CDCA3 25402006 pred P G GP P P P P P P P GP P P P P P P P GP CDCA3 C1orf112 25402006 pred P G GP P P P P P P P P P P P P P P P GP STIL CDCA3 25402006 pred G G G G G G G G G G G G G G G G G G G G RRM2 CDCA3 25402006 pred G G G G G G G GP G GP G GP G G G G G G GP G G GP G PIR51 CDCA3 25402006 pred G G P GP GP P P GP GP GP CTPS1 CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CDCA3 CDC6 25402006 pred P G GP P G P P P P P P GP P G P P P P P P GP SKP2 CDCA3 25402006 pred G GP G G GP P G GP GP P GP GP G GP P G G G GP G GP GP GP GP GP G CDCA3 ANLN 25402006 pred G G GP P GP P P P P G GP P P GP GP EZH2 CDCA3 25402006 pred G P G GP GP P GP G GP G P P GP GP GP GP MCM3 CDCA3 25402006 pred G G G G GP G G GP G GP G GP G G G GP G G GP G GP GP G TYMS CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP G GP GP GP GP GP G NFKBIE CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G GP GP GP GP GP GP GP G CENPA CDCA3 25402006 pred G GP G G GP P G G GP P P GP GP G GP P G G G GP G GP GP GP GP GP G OIP5 CDCA3 25402006 pred GP G G G P GP P GP G GP GP G GP GP GP DDX39A CDCA3 25402006 pred G GP G G GP P G GP GP P P GP G G GP P G G G GP GP GP GP G GP GP G CDCA3 FAM83D 25402006 pred G G G G G G G GP P G GP GP G G G G GP GP GP GP G ERCC6L CDCA3 25402006 pred P P P P P P P P P P P P P P P P PTTG1 CDCA3 25402006 pred G G G G GP G G GP G GP G GP G G G GP G G GP GP G GP G CDCA3 RACGAP1 25402006 pred G G G GP G G GP P G GP G GP G G GP G G GP G GP GP G CDCA3 DBF4 25402006 pred G G P G P P G G G G P G G G GP CDCA3 EXO1 25402006 pred G G G G G G G G G G G G BIRC5 CDCA3 25402006 pred G GP P GP GP P G GP P P GP GP GP KIF20A CDCA3 25402006 pred P G GP P GP GP P P P P GP P P P P GP P GP GP CEP55 CDCA3 25402006 pred P G G P P GP P P P P GP P P P P GP GP GP CDC25A CDCA3 25402006 pred G GP P P P P P P P P P P P P P GP SGOL2 CDCA3 25402006 pred G G G G G G G GP G GP G G G G G GP GP TOP2A CDCA3 25402006 pred P G GP GP P GP GP G P GP GP GP GP TROAP CDCA3 25402006 pred G GP G G GP P G GP GP P GP GP G GP P G G G GP GP GP GP GP GP GP G CUL7 CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CDCA3 DTL 25402006 pred P G GP P G P P P G P G P P G G G GP DLGAP5 CDCA3 25402006 pred G GP P G P P P GP P P GP P P P GP TTK CDCA3 25402006 pred P G GP P P GP P P P P GP P P P P GP P GP GP CENPN CDCA3 25402006 pred G G G G G G G G G G G G CDCA3 FBXO44 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G GP GP GP GP GP GP GP G RFC4 CDCA3 25402006 pred G GP G G GP P G G GP P GP GP G GP P G G G GP GP G GP GP GP GP G CDCA3 FBXO6 25402006 pred G GP G G GP P G G GP P P GP GP G GP P G G G P GP GP GP GP GP GP G CKS1B CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CDCA8 CDCA3 25402006 pred P G GP P GP P G G G GP FBXO18 CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CKS2 CDCA3 25402006 pred G GP G GP P G GP GP P P GP GP G GP P G GP P P GP GP GP GP G PBK CDCA3 25402006 pred G GP P P GP P P P P GP P P P GP P GP GP CDCA3 CCDC167 25402006 pred G P G G GP P G GP P P GP GP G GP P G G GP P GP GP GP GP GP G SMC2 CDCA3 25402006 pred G G G G G G G G G CDCA3 FBXL2 25402006 pred G G G G G G G G G G G G G G G G PLK4 CDCA3 25402006 pred P G GP P P GP P P P P P P P P P GP GP CDCA3 FBXL3 25402006 pred G G G G GP G G G G G G G G G G G G G G GP G G G E2F1 CDCA3 25402006 pred GP G G GP P G GP GP P P GP GP GP P G G G P GP P GP P GP GP G FEN1 CDCA3 25402006 pred G GP G G GP P G G GP P P GP GP G GP P G G G GP GP G GP GP GP GP G ZC3HC1 CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G KIF4A CDCA3 25402006 pred P G GP P G P GP P P P P GP P G G P P P GP P P GP KIF18A CDCA3 25402006 pred P G GP P P P P P P P P P P P P P P P GP NDC80 CDCA3 25402006 pred G G G G WHSC1 CDCA3 25402006 pred GP G G GP P G GP GP P P GP GP GP P G G G GP GP GP GP P GP GP G CDCA3 TCF19 25402006 pred G G G G G G G G G G G G G G G G G G G G G KIF23 CDCA3 25402006 pred P G GP P P P P P P P P P P P P P P P GP CDCA3 FBXO4 25402006 pred G G G G G G G G G G G G G G G G G G G G CDCA3 SPC25 25402006 pred G GP P P P GP P GP P P P CDCA3 FBXW2 25402006 pred G GP G G GP P G GP GP P P GP G G GP P G G G G GP GP GP G GP GP G BRCA1 CDCA3 25402006 pred P G GP P P P P P P P GP P P P P P P P GP BLM CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CCNB1 CDCA3 25402006 pred G G GP G G GP P GP GP G G G GP P GP P GP GP UBE2S CDCA3 25402006 pred G G G G G G G GP G GP G G G G G G G G G GP G PLK1 CDCA3 25402006 pred P G G GP P G GP GP P P P GP GP P G G G GP GP GP GP P P GP CHEK1 CDCA3 25402006 pred G G G GP CHAF1A CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP G GP GP GP GP G CDCA3 ECT2 25402006 pred G G G G G G G G G G NCAPH CDCA3 25402006 pred G GP P P P G P P P GP HJURP CDCA3 25402006 pred G GP P GP GP P P P P G GP P G P GP P GP P GP GP ESPL1 CDCA3 25402006 pred G GP G G GP P GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G TK1 CDCA3 25402006 pred G GP G GP P G G GP P GP GP GP P G G G GP G G GP GP G DEPDC1 CDCA3 25402006 pred P G G P G G GP P GP P G G G GP P G P P GP GP UBE2C CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CDCA3 NDC1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G CDCA3 UBE2T 25402006 pred G G G P G GP P P P GP P GP G GP P GP G MCM6 CDCA3 25402006 pred G GP G G GP P G G GP P GP GP G GP P G G G GP GP GP GP GP GP GP G CENPF CDCA3 25402006 pred G GP G GP P G GP GP P P P GP GP P G G GP GP GP GP GP GP GP FBXL8 CDCA3 25402006 pred P P P P P P P P P P P P P P P CDKN3 CDCA3 25402006 pred G GP G G GP P G GP GP P P P GP G GP P G G G GP GP GP GP P GP GP CDCA3 TACC3 25402006 pred G GP P GP P P GP GP P P P GP GP GP GP SHCBP1 CDCA3 25402006 pred G GP P P P P P P P P P P P GP FBXO46 CDCA3 25402006 pred G G G G G P G G GP G G G GP P G G G G G GP GP G GP GP G AURKB CDCA3 25402006 pred P G GP P G GP P P P GP P G P P GP P GP P CDCA3 FBXO2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G RNASEH2A CDCA3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G CDCA3 ZWILCH 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP P GP GP GP GP GP CENPE CDCA3 25402006 pred P G GP P P P P P P P P P P P P P P GP CCNB2 CDCA3 25402006 pred P G GP P G GP GP P G GP GP P G G G GP G P GP P GP GP G MCM10 CDCA3 25402006 pred G GP P P P P P G P G P P HMGB2 CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G PSRC1 CDCA3 25402006 pred G G G G G P G GP G P G G G G P G G G G G GP G G GP G G CDCA3 GINS2 25402006 pred P G GP P GP P P P GP P GP GP GP CDCA3 KIF15 25402006 pred P G GP P P GP P P GP P P P P GP P GP GP KIF11 CDCA3 25402006 pred P G GP P P GP P P P P GP P P P P P P GP GP PRC1 CDCA3 25402006 pred G P G G GP P G GP GP P P P GP G GP P G G GP P P GP GP G GP FBXO31 CDCA3 25402006 pred G GP G P P G GP GP P GP GP G GP P G G G GP GP GP GP GP GP GP G E2F8 CDCA3 25402006 pred G G G G G G G G KPNA2 CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G CDCA3 FAM64A 25402006 pred G G G G P G GP P P P G G GP P G G G GP GP GP GP G P G G GINS1 CDCA3 25402006 pred G P G G GP P G GP P P P P G GP P G GP G GP GP GP GP FBXW5 CDCA3 25402006 pred G GP G G GP P G GP GP P P GP G G GP P G G G GP GP GP GP G GP GP G RAD54L CDCA3 25402006 pred P G GP P P GP P P P P GP P G P P GP P P P GP SPAG5 CDCA3 25402006 pred GP G G GP P G GP GP P P GP GP GP P G G G GP P GP GP GP GP GP G CDCA3 CACYBP 25402006 pred G GP G G GP P G G GP P P GP GP G GP P G G G GP GP G GP GP GP GP G KIAA0101 CDCA3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G CDCA2 CDCA3 25402006 pred P G GP P GP GP P P P P GP P P P P P P P GP NCAPD2 CDCA3 25402006 pred G GP G G GP P G GP GP P P GP GP G GP P G G G GP GP GP GP GP GP GP G BUB1B CDCA3 25402006 pred P G GP P GP GP P P P GP GP P G GP P P GP P GP GP G SPC24 CDCA3 25402006 pred P G GP P P P GP P P P P P MELK CDCA3 25402006 pred P G GP P GP GP P P P GP GP P G G GP P P GP GP GP GP NEIL3 CDCA3 25402006 pred G G G G G G G G G G G G G G SKA3 CDCA3 25402006 pred G P G G GP P G GP GP P P P GP G GP P G G G P P GP GP GP GP GP G CDCA3 FANCI 25402006 pred G P G GP P GP GP P P P GP G GP P G G GP GP P GP GP GP GP G NCAPG2 CDCA3 25402006 pred G P G GP P G GP GP P P P GP G GP P G G G P P P GP GP GP GP CDCA3 CENPM 25402006 pred P G GP P P GP P P P GP GP P P P P P P P P MAD2L1 CDCA3 25402006 pred P G G P P GP P P P GP G GP P G P P GP GP GP GP CDCA3 FBXO34 25402006 pred G GP G G G G G GP G G G G G G G GP G GP G G GP GP G LIG1 CDCA3 25402006 pred G P G G GP P P GP P P GP GP G GP P G G G GP P GP GP GP GP GP G MCM7 CDCA3 25402006 pred G GP G G GP G G GP G GP G GP G G G GP GP G GP G GP GP G HMMR CDCA3 25402006 pred G GP P P GP P G P P G GP GP MYBL2 CDCA3 25402006 pred P G GP P P P P P P GP GP P G G P P P GP GP GP GP CDCA3 TPX2 25402006 pred G P G GP P G G GP P P P GP G GP P G G G GP GP GP G GP GP G CDCA3 NUSAP1 25402006 pred G GP G GP G G GP P G GP G GP G G G GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q99618 P05067-7 pull down 21832049 direct interaction X 2 Q99618 Q02809 biochemical 22939629 colocalization X 2 Q99618 D6W5D9 two hybrid 21988832 direct interaction X 2 Q99618 A0A024RBA6 two hybrid 25416956 direct interaction X 2 Q99618 pull down 12679038 direct interaction X 2 P0CG48 Q99618 affinity chromatography technology 20581839 physical association X 2 P0CG48 Q99618 affinity chromatography technology 21139048 physical association X 2 Q13077-2 Q99618 two hybrid 25416956 direct interaction X 2 P63208 Q99618 two hybrid 19159283 direct interaction X 2 P63208 Q99618 affinity chromatography technology 15070733 physical association X 2 P63208 Q99618 biochemical 12679038 colocalization X 2 P63208 Q99618 pull down 12679038 direct interaction X 2 P63208 Q99618 affinity chromatography technology 12679038 physical association X 2 O95817 Q99618 affinity chromatography technology 23824909 physical association X 2 A0A090N7U0 Q99618 pull down 12679038 direct interaction X 2 A0A090N7U0 Q99618 affinity chromatography technology 12679038 physical association X 2 A0A024R8H5 Q99618 two hybrid 25416956 direct interaction X 2 A0A024R8H5 Q99618 two hybrid 16189514 direct interaction X 2 Q99618 Q9GZU7-2 two hybrid 16189514 direct interaction X 2 Q99618 Q9GZU7-2 two hybrid 25416956 direct interaction X 2 A0A090N7U0 Q99618 in vivo 12679038 - X 2 A0A090N7U0 Q99618 in vitro 12679038 - X 2 A0A090N7U0 Q99618 in vivo 12679038 - X 2 A0A090N7U0 Q99618 in vitro 12679038 - X 2 A0A024R8H5 Q99618 two hybrid 16189514 - X 2 A0A024R8H5 Q99618 two hybrid 16189514 - X 2 Q99618 Q9GZU7-2 two hybrid 16189514 - X 2 Q99618 Q9GZU7-2 two hybrid 16189514 - X 2 P63208-2 Q99618 two hybrid 12679038 - X 2 P63208-2 Q99618 in vitro 12679038 - X 2 P63208-2 Q99618 in vivo 12679038 - X 2 P63208-2 Q99618 in vitro 12679038 - X 2 P63208-2 Q99618 in vivo 12679038 - X 2 P63208-2 Q99618 two hybrid 12679038 - X 2 P30291-2 Q99618 in vitro 12679038 - X 2 P30291-2 Q99618 in vivo 12679038 - X 2 P30291-2 Q99618 in vivo 12679038 - X 2 P30291-2 Q99618 in vitro 12679038 - X 2 Q99618 A0A024R461 two hybrid pooling approach 16189514 physical association X 2 Q99618 D6W5D9 two hybrid array 21988832 physical association X 2 Q99618 A0A024RBA6 two hybrid prey pooling approach 25416956 physical association X 2 Q99618 A0A024RBA6 two hybrid prey pooling approach 25416956 physical association X 2 Q99618 A0A024R461 two hybrid prey pooling approach 25416956 physical association X 2 Q99618 A0A024RBA6 two hybrid array 25416956 physical association X 2 Q99618 A0A024RBA6 two hybrid array 25416956 physical association X 2 Q99618 A0A024R461 two hybrid array 25416956 physical association X 2 Q99618 A0A024RBA6 validated two hybrid 25416956 physical association X 2 Q99618 A0A024R461 validated two hybrid 25416956 physical association X 2 Q13077 Q99618 two hybrid prey pooling approach 25416956 physical association X 2 Q13077 Q99618 two hybrid array 25416956 physical association X 2 Q13077 Q99618 validated two hybrid 25416956 physical association X 2 P63208 Q99618 mammalian protein protein interaction trap 19159283 physical association X 2 A0A024R8H5 Q99618 two hybrid pooling approach 16189514 physical association X 2 A0A024R8H5 Q99618 two hybrid prey pooling approach 25416956 physical association X 2 A0A024R8H5 Q99618 two hybrid array 25416956 physical association X 2 A0A024R8H5 Q99618 validated two hybrid 25416956 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CUL1 CDCA3 MI:0096(pull down)|MI:0493(in vivo) 12679038 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_89721|HPRD_12043 prey|- bait|- BAG3 CDCA3 MI:0004(affinity chromatography technology) 23824909 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_282922 bait prey SKP1 CDCA3 MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0231(mammalian protein protein interaction trap) 12679038,15070733,19159283 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(intact) BIOGRID_89720|BIOGRID_197006|BIOGRID_89719|BIOGRID_219147|HPRD_9120|UniProt_98766 prey|bait|prey|prey|-|bait bait|prey|bait|bait|-|prey WEE1 CDCA3 MI:0096(pull down)|MI:0493(in vivo) 12679038 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_89722|HPRD_4918 prey|- bait|- CDCA3 CTDSP1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(intact)|(biogrid) MINT_69315|HPRD_22582|MINT_40020|UniProt_153782|BIOGRID_80955 prey|-|prey|unspecified role|prey bait|-|bait|unspecified role|bait CDCA3 BCL11A MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_288765|UniProt_118417 prey|unspecified role bait|unspecified role APP CDCA3 MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_229293 prey bait CDCA3 TRAF2 MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_65759|MINT_36617 prey|prey bait|bait PLOD1 CDCA3 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_241425 prey bait TRAF2 CDCA3 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(intact) HPRD_21847|BIOGRID_78585|UniProt_151444 -|bait|unspecified role -|prey|unspecified role

PPI - HINT Gene A Gene B PMID Method Quality CTDSP2 CDCA3 26186194 0004 HT CTDSPL CDCA3 26186194 0004 HT CTDNEP1 CDCA3 26186194 0004 HT ATP6V1C1 CDCA3 26186194 0004 HT NMT1 CDCA3 26186194 0004 HT SKP1 CDCA3 12679038,12679038,12679038,15070733,12679038 0401,0004,0018,0004,0096 LC PLOD1 CDCA3 22939629 0401 HT LAMTOR4 CDCA3 26186194 0004 HT GTF2H5 CDCA3 26496610,26496610 0007,0004 HT TMEM17 CDCA3 26638075,26638075 1314,1313 HT CDCA3 PARD6B 26496610,26496610 0007,0004 HT CDCA3 CTDSP1 26186194 0004 HT CDCA3 TMEM216 26638075,26638075 1314,1313 HT CDCA3 CHORDC1 26496610,26496610 0007,0004 HT CDCA3 FZR1 26186194 0004 HT CTDSP2 CDCA3 26186194 0004 HT CTDSPL CDCA3 26186194 0004 HT CTDNEP1 CDCA3 26186194 0004 HT ATP6V1C1 CDCA3 26186194 0004 HT NMT1 CDCA3 26186194 0004 HT PLOD1 CDCA3 22939629 0401 HT LAMTOR4 CDCA3 26186194 0004 HT GTF2H5 CDCA3 26496610,26496610 0007,0004 HT TMEM17 CDCA3 26638075,26638075 1314,1313 HT CDCA3 PARD6B 26496610,26496610 0007,0004 HT CDCA3 CTDSP1 26186194 0004 HT CDCA3 TMEM216 26638075,26638075 1314,1313 HT CDCA3 CHORDC1 26496610,26496610 0007,0004 HT CDCA3 FZR1 26186194 0004 HT SKP1 CDCA3 12679038,12679038,12679038,15070733,12679038 0401,0004,0018,0004,0096 LC CTDSP2 CDCA3 21516116,25416956,25416956,25416956,25416956 0018,0397,1112,0018,1356 HT SKP1 CDCA3 12679038,19159283,12679038,12679038,19159283,12679038 0401,0231,0004,0018,0018,0096 LC PLOD1 CDCA3 22939629 0401 LC TRAF2 CDCA3 16189514,25416956,25416956,25416956,16189514,25416956 0398,1112,0397,0018,0018,1356 HT TRAF1 CDCA3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT CDCA3 CTDSP1 16189514,25416956,25416956,25416956,16189514,25416956 0398,0397,1112,0018,0018,1356 HT CDCA3 BCL11A 21988832,21988832 0397,0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q99618 Q6A065 CDCA3 CEP170 0.126 26496610 Q99618 Q86X19 CDCA3 TMEM17 0.126 26638075 Q99618 O95817 CDCA3 BAG3 0.126 23824909 Q9P0N5 Q99618 TMEM216 CDCA3 0.236 26638075 Q9Z1S0 Q99618 BUB1B CDCA3 0.236 26496610 Q9WTX6 Q99618 CUL1 CDCA3 0.236 26496610 Q9UHD1 Q99618 CHORDC1 CDCA3 0.236 26496610 Q99618 O14595 CDCA3 CTDSP2 0.61 25416956,21516116,26186194 Q99618 Q13616 CDCA3 CUL1 0.454 12679038 Q9BYG5 Q99618 PARD6B CDCA3 0.236 26496610 Q9H165 Q99618 BCL11A CDCA3 0.286 21988832 Q9D7F7 Q99618 CHMP4C CDCA3 0.236 26496610 Q99618 Q6ZYL4 CDCA3 GTF2H5 0.236 26496610 Q99618 Q7TSY8 CDCA3 SGOL2 0.236 26496610 Q99618 Q8BHX3 CDCA3 CDCA8 0.236 26496610 Q99618 Q8C5L3 CDCA3 CNOT2 0.236 26496610 Q99618 O35942 CDCA3 NEK2 0.236 26496610 Q99618 O88520 CDCA3 SHOC2 0.236 26496610 Q99618 Q13077 CDCA3 TRAF1 0.583 25416956,unassigned1304 Q99618 Q12933 CDCA3 TRAF2 0.702 25416956,16189514,unassigned1304 Q99618 O15194 CDCA3 CTDSPL 0.332 unassigned1304,26186194 Q9GZU7 Q99618 CTDSP1 CDCA3 0.74 25416956,16189514,26186194,unassigned1304 Q99618 Q0VGL1 CDCA3 LAMTOR4 0.126 26186194 Q99618 P21283 CDCA3 ATP6V1C1 0.126 26186194 Q99618 O95476 CDCA3 CTDNEP1 0.126 26186194 Q99618 P05067 CDCA3 APP 0.183 21832049 Q99618 Q02809 CDCA3 PLOD1 0.081 22939629 Q99618 P30291 CDCA3 WEE1 0.309 12679038 Q99618 P30419 CDCA3 NMT1 0.126 26186194 Q9UM11 Q99618 FZR1 CDCA3 0.126 26186194 Q99618 H7BX26 CDCA3 H7BX26 0.126 26496610 Q99618 P63208 CDCA3 SKP1 0.794 19159283,15070733,12679038

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 CTDSP2 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database CTDSPL CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database BUB1B CDCA3 MI:0362 inference MI:0461 interaction database CTDNEP1 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database BAG3 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database APP CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database UBC CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database ATP6V1C1 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database WEE1 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database NMT1 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database NEK2 CDCA3 MI:0362 inference MI:0461 interaction database SKP1 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database RBL2 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database LAMTOR4 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database TRAF2 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database TRAF1 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database CUL1 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database E2F4 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database CDCA8 CDCA3 MI:0362 inference MI:0461 interaction database SGO2 CDCA3 MI:0362 inference MI:0461 interaction database CEP170 CDCA3 MI:0362 inference MI:0461 interaction database GTF2H5 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database TMEM17 CDCA3 MI:0045 experimental interaction detection MI:0461 interaction database CHMP4C CDCA3 MI:0362 inference MI:0461 interaction database CDCA3 PARD6B MI:0045 experimental interaction detection MI:0461 interaction database CDCA3 CTDSP1 MI:0045 experimental interaction detection MI:0461 interaction database CDCA3 BCL11A MI:0045 experimental interaction detection MI:0461 interaction database CDCA3 CNOT2 MI:0362 inference MI:0461 interaction database CDCA3 TMEM216 MI:0045 experimental interaction detection MI:0461 interaction database CDCA3 CHORDC1 MI:0045 experimental interaction detection MI:0461 interaction database CDCA3 FZR1 MI:0045 experimental interaction detection MI:0461 interaction database CDCA3 SHOC2 MI:0362 inference MI:0461 interaction database