Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 6 90642998 rs292257 T C rs292257 1.65E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 T intron GWASdb_drug 6 90643281 rs292255 T C rs292255 1.85E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 T intron GWASdb_drug 6 90643949 rs17708487 T C rs17708487 5.11E-04 GEMCITABINE|CYTARABINE MANNOSYLTRANSFERASES|PIGB PROTEIN, HUMAN|RNA, SMALL INTERFERING|DEOXYCYTIDINE Response to cytadine analogues (cytosine arabinoside) HPOID:0002664 DOID:162 T intron GWASdb_drug 6 90657783 rs404256 T C rs404256 5.00E-06 IMMUNOGLOBULIN G GLYCOSYLTRANSFERASES IgG glycosylation HPOID:0010701 DOID:2531|DOID:417 T intron GWASdb_drug 6 90657783 rs404256 T C rs404256 7.00E-09 IMMUNOGLOBULIN G GLYCOSYLTRANSFERASES IgG glycosylation HPOID:0010701 DOID:2531|DOID:417 T intron GWASdb_drug 6 90880393 rs10944479 G A rs10944479 4.00E-08 THYROTROPIN AUTOANTIBODIES|THYROID MICROSOMAL ANTIBODIES|IODIDE PEROXIDASE Thyroid peroxidase antibody positivity HPOID:0100646|HPOID:0000836|HPOID:0000821 DOID:7188|DOID:1459|DOID:7998 G intron GWASdb_drug 6 90638963 rs1055403 G A rs1055403 2.23E-04 Multiple complex diseases HPOID:0000118 NA C UTR-3 GWASdb_trait 6 90640491 rs2289577 C T rs2289577 9.00E-06 Cognitive performance HPOID:0100543 DOID:1561 G UTR-3 GWASdb_trait 6 90641522 rs10455512 T C rs10455512 3.79E-04 Response to platinum-based chemotherapy in non-small-cell lung cancer HPOID:0100526 DOID:3908 T UTR-3 GWASdb_trait 6 90642998 rs292257 T C rs292257 1.65E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 T intron GWASdb_trait 6 90643281 rs292255 T C rs292255 1.85E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 T intron GWASdb_trait 6 90643949 rs17708487 T C rs17708487 5.11E-04 Response to cytadine analogues (cytosine arabinoside) HPOID:0002664 DOID:162 T intron GWASdb_trait 6 90646226 rs292251 G A rs292251 4.62E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 T intron GWASdb_trait 6 90647154 rs292250 G A rs292250 4.53E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 A intron GWASdb_trait 6 90647759 rs182382 G C rs182382 4.53E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 G intron GWASdb_trait 6 90651086 rs3734662 C T rs3734662 8.32E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 A intron GWASdb_trait 6 90651086 rs3734662 C T rs3734662 1.15E-04 Major depression (suicidal thoughts and behavior) HPOID:0000716 DOID:1470 A intron GWASdb_trait 6 90651785 rs210052 T C rs210052 4.44E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 A intron GWASdb_trait 6 90652100 rs210051 A G rs210051 3.45E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 C intron GWASdb_trait 6 90657783 rs404256 T C rs404256 7.56E-05 Prion diseases HPOID:0004429 DOID:649 T intron GWASdb_trait 6 90657783 rs404256 T C rs404256 5.00E-06 IgG glycosylation HPOID:0010701 DOID:2531|DOID:417 T intron GWASdb_trait 6 90657783 rs404256 T C rs404256 7.00E-09 IgG glycosylation HPOID:0010701 DOID:2531|DOID:417 T intron GWASdb_trait 6 90660319 rs9451298 T C rs9451298 2.51E-05 Coronary heart disease HPOID:0001677 DOID:3393 C cds-synon GWASdb_trait 6 90660319 rs9451298 T C rs9451298 2.51E-05 Coronary heart disease HPOID:0001677 DOID:3393 C cds-synon GWASdb_trait 6 90671114 rs176713 T C rs176713 5.31E-05 Type 2 diabetes HPOID:0005978 DOID:9352 A intron GWASdb_trait 6 90671114 rs176713 T C rs176713 2.73E-04 Stroke HPOID:0001297 DOID:6713 A intron GWASdb_trait 6 90674451 rs16882302 C T rs16882302 2.28E-07 Alcohol and nictotine co-dependence HPOID:0000707 DOID:0050741|DOID:0050742 C intron GWASdb_trait 6 90681466 rs6917758 A C rs6917758 3.00E-06 Obesity-related traits HPOID:0001513 DOID:9970 A intron GWASdb_trait 6 90698274 rs12204127 C T rs12204127 6.00E-07 Visceral adipose tissue/subcutaneous adipose tissue ratio HPOID:0009124 DOID:9970 C intron GWASdb_trait 6 90706217 rs16882337 C G rs16882337 5.57E-04 Body mass index HPOID:0001507 DOID:9970 C intron GWASdb_trait 6 90731445 rs16882357 T C rs16882357 1.38E-04 Body mass index HPOID:0001507 DOID:9970 T intron GWASdb_trait 6 90731445 rs16882357 T C rs16882357 4.37E-04 Body mass index HPOID:0001507 DOID:9970 T intron GWASdb_trait 6 90731445 rs16882357 T C rs16882357 5.16E-04 Body mass index HPOID:0001507 DOID:9970 T intron GWASdb_trait 6 90732877 rs12664550 T C rs12664550 5.75E-04 Body mass index HPOID:0001507 DOID:9970 T intron GWASdb_trait 6 90732877 rs12664550 T C rs12664550 7.05E-04 Body mass index HPOID:0001507 DOID:9970 T intron GWASdb_trait 6 90732877 rs12664550 T C rs12664550 9.72E-05 Body mass index HPOID:0001507 DOID:9970 T intron GWASdb_trait 6 90733337 rs9444730 T G rs9444730 1.00E-05 Hepatocellular carcinoma (hepatitis B virus related) HPOID:0001402 DOID:684 T intron GWASdb_trait 6 90733337 rs9444730 T G rs9444730 6.09E-08 Metabolite levels HPOID:0001939 DOID:655 T intron GWASdb_trait 6 90734082 rs12663434 C A rs12663434 3.00E-05 Hepatocellular carcinoma (hepatitis B virus related) HPOID:0001402 DOID:684 C intron GWASdb_trait 6 90734908 rs4388268 G A rs4388268 9.74E-08 Metabolite levels HPOID:0001939 DOID:655 G intron GWASdb_trait 6 90734984 rs7749730 A G rs7749730 1.00E-05 Hepatocellular carcinoma (hepatitis B virus related) HPOID:0001402 DOID:684 A intron GWASdb_trait 6 90743965 rs4141551 G A rs4141551 1.63E-04 Body mass index HPOID:0001507 DOID:9970 T intron GWASdb_trait 6 90745320 rs12662903 A G rs12662903 1.92E-04 Body mass index HPOID:0001507 DOID:9970 A intron GWASdb_trait 6 90745320 rs12662903 A G rs12662903 7.41E-04 Body mass index HPOID:0001507 DOID:9970 A intron GWASdb_trait 6 90745875 rs9353713 C T rs9353713 3.60E-04 Body mass index HPOID:0001507 DOID:9970 T intron GWASdb_trait 6 90755352 rs17766774 C G rs17766774 4.60E-06 Interleukin levels (IL10, IL1Ra, IL6), in plasma HPOID:0011117 DOID:2914 C intron GWASdb_trait 6 90755887 rs4707589 G C rs4707589 1.39E-04 Body mass index HPOID:0001507 DOID:9970 C intron GWASdb_trait 6 90755887 rs4707589 G C rs4707589 5.77E-04 Body mass index HPOID:0001507 DOID:9970 C intron GWASdb_trait 6 90756453 rs9342219 C T rs9342219 4.20E-04 Body mass index HPOID:0001507 DOID:9970 C intron GWASdb_trait 6 90756453 rs9342219 C T rs9342219 8.80E-05 Body mass index HPOID:0001507 DOID:9970 C intron GWASdb_trait 6 90771812 rs9342220 G A rs9342220 1.39E-06 Body mass index HPOID:0001507 DOID:9970 G intron GWASdb_trait 6 90771812 rs9342220 G A rs9342220 3.22E-05 Body mass index HPOID:0001507 DOID:9970 G intron GWASdb_trait 6 90785351 rs4707593 G A rs4707593 3.16E-04 Body mass index HPOID:0001507 DOID:9970 G intron GWASdb_trait 6 90797100 rs4707595 C T rs4707595 3.82E-04 Body mass index HPOID:0001507 DOID:9970 C intron GWASdb_trait 6 90797349 rs4707597 A G rs4707597 6.12E-04 Body mass index HPOID:0001507 DOID:9970 G intron GWASdb_trait 6 90800254 rs4707599 T C rs4707599 7.45E-04 Body mass index HPOID:0001507 DOID:9970 C intron GWASdb_trait 6 90809639 rs7753008 T C rs7753008 2.70E-07 Celiac disease HPOID:0001438 DOID:10608 T intron GWASdb_trait 6 90809639 rs7753008 T C rs7753008 0.00000027 Celiac disease HPOID:0001438 DOID:10608 T intron GWASdb_trait 6 90814199 rs6454802 C T rs6454802 2.65E-04 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 6 90815190 rs12202119 A T rs12202119 2.94E-04 Self-reported allergy HPOID:0002715 DOID:0060056 A intron GWASdb_trait 6 90819153 rs11753332 G A rs11753332 2.53E-04 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 6 90819815 rs12196749 G A rs12196749 4.39E-04 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 6 90823159 rs12194007 G T rs12194007 2.41E-04 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 6 90845036 rs2501721 T C rs2501721 2.32E-04 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 6 90852258 rs12199079 T G rs12199079 4.81E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 6 90856878 rs1010473 G T rs1010473 7.33E-05 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 6 90857028 rs1010474 T C rs1010474 6.14E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 6 90864870 rs17711850 T C rs17711850 7.09E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 6 90866227 rs7774138 T A rs7774138 8.13E-05 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 6 90876844 rs2474618 T C rs2474618 1.26E-05 Graves' disease HPOID:0100647 DOID:12361 C intron GWASdb_trait 6 90880035 rs2474619 C A rs2474619 1.07E-05 Graves' disease HPOID:0100647 DOID:12361 A intron GWASdb_trait 6 90880035 rs2474619 C A rs2474619 2.00E-08 Celiac disease HPOID:0001438 DOID:10608 A intron GWASdb_trait 6 90880393 rs10944479 G A rs10944479 2.51E-04 Response to taxane treatment (placlitaxel) HPOID:0100526 DOID:1324 G intron GWASdb_trait 6 90880393 rs10944479 G A rs10944479 4.00E-08 Thyroid peroxidase antibody positivity HPOID:0100646|HPOID:0000836|HPOID:0000821 DOID:7188|DOID:1459|DOID:7998 G intron GWASdb_trait 6 90883525 rs10455168 T C rs10455168 1.88E-04 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 6 90886824 rs10806423 C T rs10806423 2.04E-04 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 6 90892399 rs2501716 C G rs2501716 7.45E-06 Type 1 diabetes HPOID:0100651 DOID:9744 G intron GWASdb_trait 6 90899561 rs2501720 G A rs2501720 4.49E-05 Graves' disease HPOID:0100647 DOID:12361 A intron GWASdb_trait 6 90903990 rs2064870 T C rs2064870 3.59E-04 Self-reported allergy HPOID:0002715 DOID:0060056 A intron GWASdb_trait 6 90905047 rs766153 A G rs766153 5.52E-04 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 6 90908057 rs4997561 C T rs4997561 2.70E-04 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 6 90909157 rs17712288 G A rs17712288 3.86E-04 Self-reported allergy HPOID:0002715 DOID:0060056 A intron GWASdb_trait 6 90912594 rs12209546 C T rs12209546 1.48E-05 Graves' disease HPOID:0100647 DOID:12361 C intron GWASdb_trait 6 90916345 rs3734660 T C rs3734660 7.61E-05 Serum metabolites HPOID:0011111 NA G UTR-5 GWASdb_trait 6 90916345 rs3734660 T C rs3734660 4.66E-04 Self-reported allergy HPOID:0002715 DOID:0060056 G UTR-5 GWASdb_trait 6 90917314 rs10944481 G A rs10944481 4.90E-04 Self-reported allergy HPOID:0002715 DOID:0060056 A intron GWASdb_trait 6 90921740 rs370409 C A rs370409 2.00E-06 Graves' disease HPOID:0100647 DOID:12361 T intron GWASdb_trait 6 90921988 rs1319433 G A rs1319433 4.08E-04 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 6 90926612 rs10806425 C A rs10806425 4.00E-10 Celiac disease HPOID:0001438 DOID:10608 C intron GWASdb_trait 6 90926612 rs10806425 C A rs10806425 4.00E-10 Asthma HPOID:0002099 DOID:2841 C intron GWASdb_trait 6 90926612 rs10806425 C A rs10806425 3.89E-10 Celiac disease and Rheumatoid arthritis HPOID:0001438|HPOID:0001370 DOID:10608|DOID:7148 C intron GWASdb_trait 6 90926612 rs10806425 C A rs10806425 3.89E-10 Multiple sclerosis HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 DOID:2377 C intron GWASdb_trait 6 90926612 rs10806425 C A rs10806425 3.46E-04 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 6 90927728 rs206916 T C rs206916 3.60E-05 Graves' disease HPOID:0100647 DOID:12361 G intron GWASdb_trait 6 90929301 rs9344996 T C rs9344996 7.68E-06 Graves' disease HPOID:0100647 DOID:12361 T intron GWASdb_trait 6 90929301 rs9344996 T C rs9344996 1.90E-05 Graves' disease HPOID:0100647 DOID:12361 T intron GWASdb_trait 6 90936894 rs206913 C A rs206913 2.85E-05 Graves' disease HPOID:0100647 DOID:12361 T intron GWASdb_trait 6 90941240 rs11757155 C T rs11757155 5.04E-04 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 6 90941289 rs2021716 C T rs2021716 3.90E-04 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 6 90946479 rs4707609 T C rs4707609 8.19E-04 Self-reported allergy HPOID:0002715 DOID:0060056 C intron GWASdb_trait 6 90947998 rs2655387 T C rs2655387 2.54E-06 Graves' disease HPOID:0100647 DOID:12361 G intron GWASdb_trait 6 90950391 rs16882569 C T rs16882569 1.78E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 6 90950628 rs2875584 C T rs2875584 5.17E-04 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 6 90951239 rs17513531 C T rs17513531 5.75E-04 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 6 90957463 rs3757247 C T rs3757247 1.00E-06 Type 1 diabetes HPOID:0100651 DOID:9744 A intron GWASdb_trait 6 90957463 rs3757247 C T rs3757247 8.18E-05 Graves' disease HPOID:0100647 DOID:12361 A intron GWASdb_trait 6 90957463 rs3757247 C T rs3757247 3.00E-08 Vitiligo HPOID:0001045 DOID:12306 A intron GWASdb_trait 6 90958231 rs11755527 C G rs11755527 3.36E-05 Multiple complex diseases HPOID:0000118 NA G intron GWASdb_trait 6 90958231 rs11755527 C G rs11755527 5.00E-12 Type 1 diabetes HPOID:0100651 DOID:9744 G intron GWASdb_trait 6 90958231 rs11755527 C G rs11755527 5.00E-08 Type 1 diabetes HPOID:0100651 DOID:9744 G intron GWASdb_trait 6 90958231 rs11755527 C G rs11755527 3.00E-08 Type 1 diabetes autoantibodies HPOID:0100651 DOID:9744 G intron GWASdb_trait 6 90958231 rs11755527 C G rs11755527 5.00E-12 Multiple sclerosis HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 DOID:2377 G intron GWASdb_trait 6 90958502 rs905670 G A rs905670 6.67E-04 Self-reported allergy HPOID:0002715 DOID:0060056 T intron GWASdb_trait 6 90968949 rs619192 C T rs619192 1.40E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 6 90968949 rs619192 C T rs619192 3.98E-06 Type 1 diabetes HPOID:0100651 DOID:9744 A intron GWASdb_trait 6 90973159 rs1847472 C A rs1847472 6.24E-05 Type 1 diabetes HPOID:0100651 DOID:9744 G intron GWASdb_trait 6 90973159 rs1847472 C A rs1847472 5.00E-09 Crohn's disease HPOID:0100280 DOID:8778 G intron GWASdb_trait 6 90973159 rs1847472 C A rs1847472 5.00E-09 Asthma HPOID:0002099 DOID:2841 G intron GWASdb_trait 6 90973159 rs1847472 C A rs1847472 2.00E-10 Inflammatory bowel disease HPOID:0004386 DOID:0050589 G intron GWASdb_trait 6 90973159 rs1847472 C A rs1847472 3.03E-04 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 6 90975999 rs661713 G A rs661713 1.26E-05 Graves' disease HPOID:0100647 DOID:12361 T intron GWASdb_trait 6 90976768 rs72928038 G A rs72928038 0.000000123 Graves' disease and Hashimoto's thyroiditis NA NA G intron GWASdb_trait 6 90976768 rs72928038 G A rs72928038 0.00000363 Graves' disease HPOID:0100647 DOID:12361 G intron GWASdb_trait 6 90976768 rs72928038 G A rs72928038 0.000000823 Rheumatoid arthritis HPOID:0001370 DOID:7148 G intron GWASdb_trait 6 90976768 rs72928038 G A rs72928038 0.000112 Rheumatoid arthritis (CCP positive) HPOID:0001370 DOID:7148 G intron GWASdb_trait 6 90984035 rs943689 C T rs943689 3.28E-04 Self-reported allergy HPOID:0002715 DOID:0060056 G intron GWASdb_trait 6 90986320 rs604912 A G rs604912 1.68E-04 Multiple complex diseases HPOID:0000118 NA G intron GWASdb_trait 6 90986320 rs604912 A G rs604912 9.13E-06 Type 1 diabetes HPOID:0100651 DOID:9744 G intron GWASdb_trait 6 90995817 rs953233 C T rs953233 7.86E-06 Graves' disease HPOID:0100647 DOID:12361 G intron GWASdb_trait 6 90996769 rs12212193 A G rs12212193 4.00E-08 Multiple sclerosis HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 DOID:2377 G intron GWASdb_trait 6 90999602 rs10498965 A G rs10498965 1.03E-05 Graves' disease HPOID:0100647 DOID:12361 A intron GWASdb_trait 6 91002494 rs597325 A G rs597325 1.02E-04 Graves' disease HPOID:0100647 DOID:12361 T intron GWASdb_trait 6 91002494 rs597325 A G rs597325 3.38E-10 Type 1 diabetes HPOID:0100651 DOID:9744 T intron GWASdb_trait 6 91006227 rs1504215 G A rs1504215 2.58E-04 Self-reported allergy HPOID:0002715 DOID:0060056 G UTR-5 GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000112182.14 BACH2 605394