PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus LUC7L MKRN1 26186194 biogrid exp G GP G G G GP G G GP G G G GP G G G GP G GP G GP GP G G G G GP GP G MKRN1 LUC7L2 26186194 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TP53 MKRN1 19536131 biogrid,mint,intact exp G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G CSNK1G1 MKRN1 21900206 biogrid,mint,intact exp GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G DUSP23 MKRN1 21900206 biogrid,mint,intact exp GP GP G G GP GP G G GP GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G UBE2W MKRN1 21900206 biogrid,mint,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TERT MKRN1 15805468 biogrid exp G G G G G G G CDKN1A MKRN1 19536131 biogrid,mint,intact exp GP GP G G GP G G G GP G G G GP G G GP G G G G GP G G G GP G G GP G UBC MKRN1 19536131 mint,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G EXOSC8 MKRN1 15231747 hprd,biogrid,i2d,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G MAP1LC3B MKRN1 21900206 biogrid,mint,intact exp G GP G G GP GP G G GP G GP G G G G GP GP G G G G G G G GP G GP GP G SNIP1 MKRN1 26186194 biogrid exp GP GP G G GP GP G G GP G GP GP GP G G GP GP G GP G GP G GP G GP G GP GP G UBE2D3 MKRN1 21900206 biogrid,mint,intact exp GP G G G GP GP G G GP G GP GP GP GP G G GP G GP G GP GP G G G GP GP GP G FADD MKRN1 22864571 biogrid exp GP GP G G G GP G G GP G GP G GP GP G GP GP G GP G GP G GP G GP GP GP GP G TRA2A MKRN1 26186194 biogrid exp G G G G GP GP G G G G GP G GP G G G GP G GP G G G G G G G G GP G ASH2L MKRN1 23414517 intact exp GP GP G G GP GP G G GP G GP G G G G GP GP G GP G GP GP G G GP G GP GP G RBM34 MKRN1 16082366 pred P P P P P P P P P P P P P P P G P P P P ATXN7L3 MKRN1 21836163 pred G G G G G GP G G GP G GP GP G G G GP GP G G G GP G GP G GP G GP G G RAF1 MKRN1 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G YIPF2 MKRN1 21836163 pred GP GP G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G NELFE MKRN1 16082366 pred P P P P P P P P P P P P P P P P P P ZRANB2 MKRN1 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G ZRSR1 MKRN1 16082366 pred P P P P P P P P P P P P P P P RBMX MKRN1 16082366 pred P P P P P P P P P P P P P P P P P P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants K7PPA8 Q9UHC7 anti tag coimmunoprecipitation 19536131 physical association X 2 K7PPA8 Q9UHC7 anti bait coimmunoprecipitation 19536131 physical association X 2 K7PPA8 Q9UHC7 anti bait coimmunoprecipitation 19536131 physical association X 2 K7PPA8 Q9UHC7 anti tag coimmunoprecipitation 19536131 physical association X 2 K7PPA8 Q9UHC7 anti tag coimmunoprecipitation 19536131 physical association X 2 K7PPA8 Q9UHC7 anti bait coimmunoprecipitation 19536131 physical association X 2 K7PPA8 Q9UHC7 anti tag coimmunoprecipitation 19536131 physical association X 2 K7PPA8 Q9UHC7 pull down 19536131 direct interaction X 2 Q9UBL3 Q9UHC7 two hybrid fragment pooling approach 23414517 physical association X 2 A0A024RDH2 Q9UHC7 two hybrid 21900206 physical association X 2 Q9BVJ7 Q9UHC7 two hybrid 21900206 physical association X 2 Q9UHC7 Q96B26 two hybrid 15231747 physical association X 2 Q9UHC7 Q81S56 two hybrid pooling approach 20711500 physical association X 2 Q9UHC7 Q658J6 two hybrid 21900206 physical association X 2 P0CG48 Q9UHC7 pull down 19536131 physical association X 2 Q96B02 Q9UHC7 two hybrid 21900206 physical association X 2 Q8V1H6 Q9UHC7 two hybrid 16112766 physical association X 2 A0A024R5W3 Q9UHC7 two hybrid 21900206 physical association X 2 A0A024RCX5 Q9UHC7 anti bait coimmunoprecipitation 19536131 physical association X 2 A0A024RCX5 Q9UHC7 anti bait coimmunoprecipitation 19536131 physical association X 2 A0A024RCX5 Q9UHC7 anti tag coimmunoprecipitation 19536131 physical association X 2 A0A024RCX5 Q9UHC7 anti tag coimmunoprecipitation 19536131 physical association X 2 A0A024RCX5 Q9UHC7 anti tag coimmunoprecipitation 19536131 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality HSU53209 MKRN1 26186194 0004 HT SNIP1 MKRN1 26186194 0004 HT LUC7L MKRN1 26186194 0004 HT MKRN1 LUC7L2 26186194 0004 HT HSU53209 MKRN1 26186194 0004 HT SNIP1 MKRN1 26186194 0004 HT LUC7L MKRN1 26186194 0004 HT MKRN1 LUC7L2 26186194 0004 HT UBE2D3 MKRN1 21900206 0018 HT DKFZP762B153 MKRN1 21900206 0018 HT UBE2W MKRN1 21900206 0018 HT EXOSC8 MKRN1 15231747 0018 HT DUSP23 MKRN1 21900206 0018 HT MAP1LC3B MKRN1 21900206 0018 HT CSNK1G1 MKRN1 21900206 0018 HT ASH2L MKRN1 23414517 0399 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9UHC7 Q9NQ29 MKRN1 LUC7L 0.126 26186194 Q9UHC7 Q8TAD8 MKRN1 SNIP1 0.126 26186194 Q9UHC7 Q8V1H6 MKRN1 Q8V1H6 0.309 16112766 Q9Y383 Q9UHC7 LUC7L2 MKRN1 0.126 26186194 Q9UHC7 P0CG48 MKRN1 UBC 0.21 19536131 Q9UHC7 Q8N3F0 MKRN1 MTURN 0.236 unassigned1304 Q9UHC7 Q9UER7 MKRN1 DAXX 0.236 unassigned1304 Q9Y2X8 Q9UHC7 UBE2D4 MKRN1 0.236 unassigned1304 Q9UHC7 Q96B02 MKRN1 UBE2W 0.332 21900206 Q9UHC7 Q96DC9 MKRN1 OTUB2 0.236 unassigned1304 Q9UHC7 Q13895 MKRN1 BYSL 0.236 unassigned1304 Q9UHC7 Q3B820 MKRN1 FAM161A 0.236 unassigned1304 Q9UHC7 O00560 MKRN1 SDCBP 0.236 unassigned1304 Q9UHC7 Q5VVQ6 MKRN1 YOD1 0.236 unassigned1304 Q9UHC7 P51668 MKRN1 UBE2D1 0.236 unassigned1304 Q9UHC7 P54725 MKRN1 RAD23A 0.236 unassigned1304 Q9UHC7 P54727 MKRN1 RAD23B 0.236 unassigned1304 Q9UHC7 P41227 MKRN1 NAA10 0.236 unassigned1304 Q9UHC7 P57075 MKRN1 UBASH3A 0.236 unassigned1304 Q9UHC7 P38936 MKRN1 CDKN1A 0.692 19536131 Q9UHC7 P61077 MKRN1 UBE2D3 0.332 21900206 Q9UHC7 P04637 MKRN1 TP53 0.787 19536131 Q9UHC7 Q96B26 MKRN1 EXOSC8 0.332 15231747 Q9UHC7 Q9BVJ7 MKRN1 DUSP23 0.332 21900206 Q9UHC7 O14746 MKRN1 TERT 0.21 15805468 Q9UHC7 O70133 MKRN1 DHX9 0.126 26265008 Q9UHC7 O88477 MKRN1 IGF2BP1 0.126 26265008 Q9UHC7 O88569 MKRN1 HNRNPA2B1 0.126 26265008 Q9UHC7 P11940 MKRN1 PABPC1 0.126 26265008 Q9UHC7 P23249 MKRN1 MOV10 0.126 26265008 Q9UHC7 P29341 MKRN1 PABPC1 0.126 26265008 Q9UHC7 P49312 MKRN1 HNRNPA1 0.126 26265008 Q9UHC7 P52479 MKRN1 USP10 0.126 26265008 Q9UHC7 P62960 MKRN1 YBX1 0.126 26265008 Q9UHC7 P70372 MKRN1 ELAVL1 0.126 26265008 Q9UHC7 P97379 MKRN1 G3BP2 0.126 26265008 Q9UHC7 P97855 MKRN1 G3BP1 0.126 26265008 Q9UHC7 Q13158 MKRN1 FADD 0.569 22864571 Q9UHC7 Q15717 MKRN1 ELAVL1 0.236 26265008 Q9UHC7 Q3TJZ6 MKRN1 FAM98A 0.126 26265008 Q9UHC7 Q3TLH4 MKRN1 PRRC2C 0.126 26265008 Q9UHC7 Q587J6 MKRN1 L1TD1 0.126 26265008 Q9UHC7 Q5F2E7 MKRN1 NUFIP2 0.126 26265008 Q9UHC7 Q60668 MKRN1 HNRNPD 0.126 26265008 Q9UHC7 Q60865 MKRN1 CAPRIN1 0.126 26265008 Q9UHC7 Q61584 MKRN1 FXR1 0.126 26265008 Q9UHC7 Q62167 MKRN1 DDX3X 0.126 26265008 Q9UHC7 Q6A0A2 MKRN1 LARP4B 0.126 26265008 Q9UHC7 Q6NVF9 MKRN1 CPSF6 0.126 26265008 Q9UHC7 Q6NZJ6 MKRN1 EIF4G1 0.126 26265008 Q9UHC7 Q6ZQ58 MKRN1 LARP1 0.126 26265008 Q9UHC7 Q7TMK9 MKRN1 SYNCRIP 0.126 26265008 Q9UHC7 Q7TQH0 MKRN1 ATXN2L 0.126 26265008 Q9UHC7 Q81S56 MKRN1 Q81S56 0.126 20711500 Q9UHC7 Q8BG05 MKRN1 HNRNPA3 0.126 26265008 Q9UHC7 Q8BMS1 MKRN1 HADHA 0.126 26265008 Q9UHC7 Q8BWW4 MKRN1 LARP4 0.126 26265008 Q9UHC7 Q8CCS6 MKRN1 PABPN1 0.126 26265008 Q9UHC7 Q8CJG0 MKRN1 AGO2 0.126 26265008 Q9UHC7 Q8K310 MKRN1 MATR3 0.126 26265008 Q9UHC7 Q8K3W3 MKRN1 CASC3 0.126 26265008 Q9UHC7 Q8K3Y3 MKRN1 LIN28A 0.126 26265008 Q9UHC7 Q8R081 MKRN1 HNRNPL 0.126 26265008 Q9UHC7 Q8VEK3 MKRN1 HNRNPU 0.126 26265008 Q9UHC7 Q91VR5 MKRN1 DDX1 0.126 26265008 Q9UHC7 Q925I1 MKRN1 ATAD3 0.126 26265008 Q9UHC7 Q99020 MKRN1 HNRNPAB 0.126 26265008 Q9UHC7 Q99MR6 MKRN1 SRRT 0.126 26265008 Q9UHC7 Q9CPN8 MKRN1 IGF2BP3 0.126 26265008 Q9UHC7 Q9CQE8 MKRN1 Q9CQE8 0.126 26265008 Q9UHC7 Q9CXY6 MKRN1 ILF2 0.126 26265008 Q9UHC7 Q9D824 MKRN1 FIP1L1 0.126 26265008 Q9UHC7 Q9EPU0 MKRN1 UPF1 0.126 26265008 Q9UHC7 Q9GZQ8 MKRN1 MAP1LC3B 0.183 21900206 Q9UHC7 Q9HCP0 MKRN1 CSNK1G1 0.332 21900206 Q9UHC7 Q9NZI8 MKRN1 IGF2BP1 0.236 26265008 Q9UHC7 Q9UBL3 MKRN1 ASH2L 0.126 23414517 Q9WV02 Q9UHC7 RBMX MKRN1 0.126 26265008 Q9Z2X1 Q9UHC7 HNRNPF MKRN1 0.126 26265008 Q9UHC7 Q13595 MKRN1 TRA2A 0.126 26186194 Q9UHC7 Q2MG95 MKRN1 BVLF1 {ECO:0000313|EMBL:CAJ75461.1} 0.126 22810586

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 IGF2BP3 MKRN1 MI:0362 inference MI:0461 interaction database DDX3X MKRN1 MI:0362 inference MI:0461 interaction database TERT MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database CASC3 MKRN1 MI:0362 inference MI:0461 interaction database EIF4G3 MKRN1 MI:0362 inference MI:0461 interaction database SYNCRIP MKRN1 MI:0362 inference MI:0461 interaction database RBMXL2 MKRN1 MI:0362 inference MI:0461 interaction database MYC MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database LMNA MKRN1 MI:0362 inference MI:0461 interaction database TP53 MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database HNRNPA1 MKRN1 MI:0362 inference MI:0461 interaction database UBC MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database PABPC1 MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database HNRNPL MKRN1 MI:0362 inference MI:0461 interaction database LMNB1 MKRN1 MI:0362 inference MI:0461 interaction database TAF1 MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database HNRNPA2B1 MKRN1 MI:0362 inference MI:0461 interaction database RBMX MKRN1 MI:0362 inference MI:0461 interaction database CDKN1A MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database HADHA MKRN1 MI:0362 inference MI:0461 interaction database HNF4A MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database MATR3 MKRN1 MI:0362 inference MI:0461 interaction database FXR1 MKRN1 MI:0362 inference MI:0461 interaction database HNRNPA3 MKRN1 MI:0362 inference MI:0461 interaction database HNRNPF MKRN1 MI:0362 inference MI:0461 interaction database UBE2D3 MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database MAX MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database YBX1 MKRN1 MI:0362 inference MI:0461 interaction database HNRNPU MKRN1 MI:0362 inference MI:0461 interaction database LMNB2 MKRN1 MI:0362 inference MI:0461 interaction database EIF4G1 MKRN1 MI:0362 inference MI:0461 interaction database DHX9 MKRN1 MI:0362 inference MI:0461 interaction database ILF2 MKRN1 MI:0362 inference MI:0461 interaction database FADD MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database G3BP1 MKRN1 MI:0362 inference MI:0461 interaction database TRA2A MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database HNRNPD MKRN1 MI:0362 inference MI:0461 interaction database CAPRIN1 MKRN1 MI:0362 inference MI:0461 interaction database USP10 MKRN1 MI:0362 inference MI:0461 interaction database ELAVL1 MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database CPSF6 MKRN1 MI:0362 inference MI:0461 interaction database HNRNPA1L2 MKRN1 MI:0362 inference MI:0461 interaction database PABPC1L MKRN1 MI:0362 inference MI:0461 interaction database PABPC1L2A MKRN1 MI:0362 inference MI:0461 interaction database ATAD3C MKRN1 MI:0362 inference MI:0461 interaction database L1TD1 MKRN1 MI:0362 inference MI:0461 interaction database ATAD3B MKRN1 MI:0362 inference MI:0461 interaction database ARHGAP17 MKRN1 MI:0362 inference MI:0461 interaction database LARP1 MKRN1 MI:0362 inference MI:0461 interaction database FIP1L1 MKRN1 MI:0362 inference MI:0461 interaction database LIN28B MKRN1 MI:0362 inference MI:0461 interaction database LARP4 MKRN1 MI:0362 inference MI:0461 interaction database NUFIP2 MKRN1 MI:0362 inference MI:0461 interaction database PABPN1 MKRN1 MI:0362 inference MI:0461 interaction database CPSF7 MKRN1 MI:0362 inference MI:0461 interaction database FAM98A MKRN1 MI:0362 inference MI:0461 interaction database SNIP1 MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database ATXN2L MKRN1 MI:0362 inference MI:0461 interaction database DDX1 MKRN1 MI:0362 inference MI:0461 interaction database LARP4B MKRN1 MI:0362 inference MI:0461 interaction database UPF1 MKRN1 MI:0362 inference MI:0461 interaction database UBE2W MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database EXOSC8 MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database RBMXL1 MKRN1 MI:0362 inference MI:0461 interaction database HNRNPAB MKRN1 MI:0362 inference MI:0461 interaction database DUSP23 MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database SRRT MKRN1 MI:0362 inference MI:0461 interaction database MAP1LC3B MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database PABPC3 MKRN1 MI:0362 inference MI:0461 interaction database AGO3 MKRN1 MI:0362 inference MI:0461 interaction database LIN28A MKRN1 MI:0362 inference MI:0461 interaction database MOV10 MKRN1 MI:0362 inference MI:0461 interaction database AGO4 MKRN1 MI:0362 inference MI:0461 interaction database CSNK1G1 MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database LUC7L MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database ATAD3A MKRN1 MI:0362 inference MI:0461 interaction database IGF2BP1 MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database ASH2L MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database MKRN1 AGO2 MI:0362 inference MI:0461 interaction database MKRN1 G3BP2 MI:0362 inference MI:0461 interaction database MKRN1 C14orf166 MI:0362 inference MI:0461 interaction database MKRN1 LUC7L2 MI:0045 experimental interaction detection MI:0461 interaction database MKRN1 PRRC2C MI:0362 inference MI:0461 interaction database