| PTM - CPLM | | Gene Name | UniProt ID | Type | Position | Code |
|---|
| PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | Ubiquitination | 115 | K | |
| PTM - dbPAF | | Gene Name | UniProt ID | Position | Type | Species |
|---|
| PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 18 | T | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 19 | S | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 22 | S | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 25 | S | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 27 | T | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 294 | Y | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 327 | S | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 330 | S | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 335 | S | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 49 | S | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 7 | S | Homo sapiens(Human) | | PSEN2; AD4; PS2; PSNL2; STM2 | P49810 | 9 | S | Homo sapiens(Human) | |
| PTM - PhosSNP | | Gene Name | dbSNP ID | Gene Mutation | AA Mutation | Mutation Position | Code | Peptide | Score | Modification | Type |
|---|
| PSEN2; AD4; PS2; PSNL2; STM2 | rs63750207 | CCT->CGT | P->R | 327 | S | DPEMEEDSYDSFGEP | 327 | Phosphorylation: CK1 delta | TypeIII- | | PSEN2; AD4; PS2; PSNL2; STM2 | rs63750207 | CCT->CGT | P->R | 330 | S | MEEDSYDSFGEPSYP | 330 | Phosphorylation: CK1 delta; CK2 alpha | TypeIII- | |
| PTM - PhosphositePlus | | UniProt ID | MOD_RSD | Type | SITE_+/-7_AA |
|---|
| P49810 | K306-ac | Acetylation | VWTVGMAkLDPSSQG | | P49810 | S7-p | Phosphorylation | _MLTFMAsDsEEEVC | | P49810 | S9-p | Phosphorylation | LTFMAsDsEEEVCDE | | P49810 | S19-p | Phosphorylation | EVCDERTsLMsAEsP | | P49810 | S22-p | Phosphorylation | DERTsLMsAEsPtPR | | P49810 | S25-p | Phosphorylation | TsLMsAEsPtPRSCQ | | P49810 | T27-p | Phosphorylation | LMsAEsPtPRSCQEG | | P49810 | S49-p | Phosphorylation | ENTAQWRsQENEEDG | | P49810 | Y294-p | Phosphorylation | PIFPALIySSAMVWT | | P49810 | S327-p | Phosphorylation | DPEMEEDsYDsFGEP | | P49810 | S330-p | Phosphorylation | MEEDsYDsFGEPsYP | | P49810 | S335-p | Phosphorylation | YDsFGEPsYPEVFEP | | P49810 | K115-ub | Ubiquitination | SVRFYTEkNGQLIYT | |
| PTM - dbPTM | | UniProt ID | Position | Code | Type | Resources | References |
|---|
| P49810 | 22 | S | Phosphorylation | Swiss-Prot 1010711 | 19413330 | | P49810 | 25 | S | Phosphorylation | Swiss-Prot 1010711 | 19413330 | | P49810 | 25 | S | Phosphorylation | PhosphoELM.10011 | 18669648 | | P49810 | 327 | S | Phosphorylation | PhosphoELM.10011 | 9990034;9558331 | | P49810 | 330 | S | Phosphorylation | PhosphoELM.10011 | 9990034;9558331;9558331 | | P49810 | 19 | S | Phosphorylation | PhosphoELM.10011 | 8972483;8972483 | | P49810 | 7 | S | Phosphorylation | PhosphoELM.10011 | 8972483;8972483;8972483 | | P49810 | 9 | S | Phosphorylation | PhosphoELM.10011 | 8972483;8972483;8972483 | | P49810 | 335 | S | Phosphorylation | PhosphoELM.10011 | 9558331;9558331 | | P49810 | 115 | K | Ubiquitylation | Phosphositeplus.1010730 | 21906983 | | P49810 | 19 | S | Phosphorylation | Phosphositeplus.1010730 | 8972483 | | P49810 | 22 | S | Phosphorylation | Phosphositeplus.1010730 | 20068231;20363803;22115753 | | P49810 | 25 | S | Phosphorylation | Phosphositeplus.1010730 | 18578522;18669648;19415658;20068231;20363803;22115753 | | P49810 | 327 | S | Phosphorylation | Phosphositeplus.1010730 | 9558331;9990034 | | P49810 | 330 | S | Phosphorylation | Phosphositeplus.1010730 | 9558331;9990034 | | P49810 | 335 | S | Phosphorylation | Phosphositeplus.1010730 | 9558331 | | P49810 | 7 | S | Phosphorylation | Phosphositeplus.1010730 | 8972483;9990034 | | P49810 | 9 | S | Phosphorylation | Phosphositeplus.1010730 | 8972483 | | P49810 | 27 | T | Phosphorylation | Phosphositeplus.1010730 | 18578522 | | P49810 | 22 | S | Phosphorylation | HPRD 9.0 | 19413330,19651622,20068231 | | P49810 | 25 | S | Phosphorylation | HPRD 9.0 | 18669648,19413330,19651622,18767875,19415658,18578522,20068231 | | P49810 | 27 | T | Phosphorylation | HPRD 9.0 | 18578522,20068231 | | P49810 | 7 | S | Phosphorylation (CSNK1A1) | HPRD 9.0 | 8972483 | | P49810 | 9 | S | Phosphorylation (CSNK1A1) | HPRD 9.0 | 8972483 | | P49810 | 19 | S | Phosphorylation (CSNK1A1) | HPRD 9.0 | 8972483,20068231 | | P49810 | 7 | S | Phosphorylation (CSNK1D) | HPRD 9.0 | 8972483 | | P49810 | 9 | S | Phosphorylation (CSNK1D) | HPRD 9.0 | 8972483 | | P49810 | 19 | S | Phosphorylation (CSNK1D) | HPRD 9.0 | 8972483,20068231 | | P49810 | 327 | S | Phosphorylation (CSNK1D) | HPRD 9.0 | 9990034,9558331 | | P49810 | 330 | S | Phosphorylation (CSNK1D) | HPRD 9.0 | 9990034,9558331 | | P49810 | 335 | S | Phosphorylation (CSNK1D) | HPRD 9.0 | 9558331 | | P49810 | 7 | S | Phosphorylation (CSNK2A1) | HPRD 9.0 | 8972483 | | P49810 | 9 | S | Phosphorylation (CSNK2A1) | HPRD 9.0 | 8972483 | | P49810 | 19 | S | Phosphorylation (CSNK2A1) | HPRD 9.0 | 8972483,20068231 | | P49810 | 330 | S | Phosphorylation (CSNK2A1) | HPRD 9.0 | 9990034,9558331 | | P49810 | 335 | S | Phosphorylation (CSNK2A1) | HPRD 9.0 | 9558331 | | P49810 | 329 | D | Proteolytic Cleavage | HPRD 9.0 | 9990034,9219695,10069390 | | P49810 | 326 | D | Proteolytic Cleavage | HPRD 9.0 | 9990034,9219695,10069390 | | P49810 | 329 | D | Proteolytic Cleavage | HPRD 9.0 | 9990034,9219695,10069390 | | P49810 | 329 | D | Proteolytic Cleavage | HPRD 9.0 | 9990034,9219695,10069390 | | P49810 | 329 | D | Proteolytic Cleavage | HPRD 9.0 | 9990034,9219695,10069390 | | P49810 | 326 | D | Proteolytic Cleavage | HPRD 9.0 | 9990034,9219695,10069390 | | P49810 | 329 | D | Proteolytic Cleavage | HPRD 9.0 | 10069390 | |
| PTM - HPRD | | Symbol | Position | Code | Type | References |
|---|
| PSEN2 | 19 | S | Phosphorylation | 8972483,20068231 | | PSEN2 | 22 | S | Phosphorylation | 19413330,19651622,20068231 | | PSEN2 | 25 | S | Phosphorylation | 18669648,19413330,19651622,18767875,19415658,18578522,20068231 | | PSEN2 | 27 | T | Phosphorylation | 18578522,20068231 | | PSEN2 | 326 | D | Proteolytic Cleavage | 9990034,9219695,10069390 | | PSEN2 | 327 | S | Phosphorylation | 9990034,9558331 | | PSEN2 | 328 | D | Proteolytic Cleavage | 10069390 | | PSEN2 | 328 | D | Proteolytic Cleavage | 9990034,9219695,10069390 | | PSEN2 | 329 | D | Proteolytic Cleavage | 10069390 | | PSEN2 | 329 | D | Proteolytic Cleavage | 9990034,9219695,10069390 | | PSEN2 | 329 | S | Phosphorylation | 9990034,9558331 | | PSEN2 | 330 | S | Phosphorylation | 9990034,9558331 | | PSEN2 | 334 | S | Phosphorylation | 9558331 | | PSEN2 | 335 | S | Phosphorylation | 9558331 | | PSEN2 | 7 | S | Phosphorylation | 8972483 | | PSEN2 | 9 | S | Phosphorylation | 8972483 | |
| PTM - Phospho.ELM | | UniProt | Position | Code | PMIDs | Kinase | Source | Type |
|---|
| P49810 | 9 | S | 8972483 | CK1_group | LTP | Phosphorylation | | P49810 | 9 | S | 8972483 | CK2_group | LTP | Phosphorylation | | P49810 | 9 | S | 8972483 | CK2_alpha | LTP | Phosphorylation | | P49810 | 327 | S | 9990034 | | LTP | Phosphorylation | | P49810 | 327 | S | 9558331 | CK1_delta | LTP | Phosphorylation | | P49810 | 7 | S | 8972483 | CK1_group | LTP | Phosphorylation | | P49810 | 7 | S | 8972483 | CK2_group | LTP | Phosphorylation | | P49810 | 7 | S | 8972483 | CK2_alpha | LTP | Phosphorylation | | P49810 | 330 | S | 9990034 | | LTP | Phosphorylation | | P49810 | 330 | S | 9558331 | CK1_delta | LTP | Phosphorylation | | P49810 | 330 | S | 9558331 | CK2_alpha | LTP | Phosphorylation | | P49810 | 19 | S | 8972483 | CK1_group | LTP | Phosphorylation | | P49810 | 19 | S | 8972483 | CK2_group | LTP | Phosphorylation | | P49810 | 335 | S | 9558331 | CK2_group | LTP | Phosphorylation | | P49810 | 335 | S | 9558331 | CK2_alpha | LTP | Phosphorylation | | P49810 | 25 | S | 18669648 | | HTP | Phosphorylation | |
| PTM - UniProt | | UniProt ID | Position | Type | PMIDs |
|---|
| P49810 | 22 | Phosphoserine | 20068231;23186163 | | P49810 | 25 | Phosphoserine | 20068231;23186163 | |
| PTM - PHOSIDA | | Symbol | Accession | Code | Position | Surrounding Sequence | Type |
|---|
| PSEN2 | IPI00184584 | S | 22 | ERTSLMpSAESPTP | phosphorylation | | PSEN2 | IPI00184584 | S | 25 | SLMSAEpSPTPRSC | phosphorylation | |
| PTM - BioGRID | | Entrez Gene | BioGRID ID | Position | Code | Type | PMIDs |
|---|
| 5664 | 111643 | - | K | Ubiquitination | 17614368 | | 5664 | 111643 | - | K | Ubiquitination | 21906983 | | 5664 | 111643 | - | K | Ubiquitination | 15004330 | | 5664 | 111643 | - | K | Ubiquitination | 21963094 | | 5664 | 111643 | - | K | Ubiquitination | 23707529 | |
| PTM - mUbiSiDa | | Gene Name | Species | Ubiquitination Site | Ubiquitination Sequence | Evidence PMID |
|---|
| PSEN2 | Homo sapiens (Human) | 115 | "115,VRFYTEKNGQLIY" | 115:21906983 | | PSEN2 | Homo sapiens (Human) | 115 | "115,VRFYTEKNGQLIY" | 115:21906983 | | PSEN2 | Homo sapiens (Human) | 115 | "115,VRFYTEKNGQLIY" | 115:21906983 | | PSEN2 | Homo sapiens (Human) | 148 | "148,VRFYTEKNGQLIY" | 148:21906983 | |