PTM - CPLM Gene Name UniProt ID Type Position Code NPHP1; NPH1 O15259 Ubiquitination 520 K NPHP1; NPH1 O15259 Ubiquitination 633 K

PTM - dbPAF Gene Name UniProt ID Position Type Species NPHP1; NPH1 O15259 121 S Homo sapiens(Human) NPHP1; NPH1 O15259 123 S Homo sapiens(Human) NPHP1; NPH1 O15259 126 S Homo sapiens(Human) NPHP1; NPH1 O15259 349 Y Homo sapiens(Human) NPHP1; NPH1 O15259 376 S Homo sapiens(Human) NPHP1; NPH1 O15259 379 S Homo sapiens(Human) NPHP1; NPH1 O15259 46 Y Homo sapiens(Human) NPHP1; NPH1 O15259 460 S Homo sapiens(Human) NPHP1; NPH1 O15259 474 S Homo sapiens(Human) NPHP1; NPH1 O15259 487 S Homo sapiens(Human) NPHP1; NPH1 O15259 542 T Homo sapiens(Human) NPHP1; NPH1 O15259 601 S Homo sapiens(Human) NPHP1; NPH1 O15259 721 Y Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O15259 K193-ac Acetylation PDGWWIAkDAkGNEG O15259 K196-ac Acetylation WWIAkDAkGNEGLVP O15259 Y46-p Phosphorylation PNKRQHIyQRCIQLK O15259 T102-p Phosphorylation QLQGLAVtIsRENIT O15259 S104-p Phosphorylation QGLAVtIsRENITEV O15259 S121-p Phosphorylation PTEEEEEsEsEDsED O15259 S123-p Phosphorylation EEEEEsEsEDsEDSG O15259 S126-p Phosphorylation EEsEsEDsEDSGGEE O15259 Y349-p Phosphorylation GNQFRANyFLQPELM O15259 S376-p Phosphorylation ATEGTIRsRPsRISL O15259 S379-p Phosphorylation GTIRsRPsRISLILT O15259 S460-p Phosphorylation DCFIRSNsASPDLGI O15259 S474-p Phosphorylation ILFELGIsYIRNSTG O15259 T542-p Phosphorylation SVFYQIMtMRRQPQL O15259 S601-p Phosphorylation KDRMSLQsTDLISHP O15259 Y721-p Phosphorylation FDLSEQTyDFLGEMR O15259 K520-ub Ubiquitination NGGTPYEkGIEVDPS O15259 K633-ub Ubiquitination LRSSWAGkESTLKRS

PTM - dbPTM UniProt ID Position Code Type Resources References O15259 46 Y Phosphorylation Swiss-Prot 1010711 21357692 O15259 349 Y Phosphorylation Swiss-Prot 1010711 21357692 O15259 721 Y Phosphorylation Swiss-Prot 1010711 21357692 O15259 520 K Ubiquitylation Phosphositeplus.1010730 21906983 O15259 633 K Ubiquitylation Phosphositeplus.1010730 21906983 O15259 349 Y Phosphorylation Phosphositeplus.1010730 21357692 O15259 46 Y Phosphorylation Phosphositeplus.1010730 21357692 O15259 721 Y Phosphorylation Phosphositeplus.1010730 21357692

PTM - UniProt UniProt ID Position Type PMIDs O15259 46 Phosphotyrosine; by FAK2 21357692 O15259 121 Phosphoserine; by CK2 16308564 O15259 123 Phosphoserine; by CK2 16308564 O15259 126 Phosphoserine; by CK2 16308564 O15259 349 Phosphotyrosine; by FAK2 21357692 O15259 721 Phosphotyrosine; by SRC 21357692

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 4867 110927 - K Ubiquitination 21906983

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID NPHP1 Homo sapiens (Human) 633; 520 "633,RSSWAGKESTLKR; 520,GGTPYEKGIEVDP" 633:21906983; 520:21906983 NPHP1 Homo sapiens (Human) 577; 464 "577,RSSWAGKESTLKR; 464,GGTPYEKGIEVDP" 577:21906983; 464:21906983 NPHP1 Homo sapiens (Human) 515; 402 "515,RSSWAGKESTLKR; 402,GGTPYEKGIEVDP" 515:21906983; 402:21906983 NPHP1 Homo sapiens (Human) 634; 521 "634,RSSWAGKESTLKR; 521,GGTPYEKGIEVDP" 634:21906983; 521:21906983 NPHP1 Homo sapiens (Human) 31 "31,RSSWAGKESTLKR" 31:21906983