PTM - dbPAF Gene Name UniProt ID Position Type Species VAV2 P52735 116 S Homo sapiens(Human) VAV2 P52735 119 S Homo sapiens(Human) VAV2 P52735 142 Y Homo sapiens(Human) VAV2 P52735 159 Y Homo sapiens(Human) VAV2 P52735 172 Y Homo sapiens(Human) VAV2 P52735 213 Y Homo sapiens(Human) VAV2 P52735 214 Y Homo sapiens(Human) VAV2 P52735 392 S Homo sapiens(Human) VAV2 P52735 426 Y Homo sapiens(Human) VAV2 P52735 575 T Homo sapiens(Human) VAV2 P52735 576 S Homo sapiens(Human) VAV2 P52735 583 S Homo sapiens(Human) VAV2 P52735 626 S Homo sapiens(Human) VAV2 P52735 639 S Homo sapiens(Human) VAV2 P52735 663 S Homo sapiens(Human) VAV2 P52735 769 S Homo sapiens(Human) VAV2 P52735 778 S Homo sapiens(Human) VAV2 P52735 779 S Homo sapiens(Human) VAV2 P52735 781 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P52735 K515-ac Acetylation EMAMSNIkPDKANAN P52735 S91-p Phosphorylation DKFGLRNsELFDPFD P52735 Y142-p Phosphorylation TENDDDVyRSLEELA P52735 Y159-p Phosphorylation HDLGEDIyDCVPCED P52735 Y172-p Phosphorylation EDGGDDIyEDIIKVE P52735 Y426-p Phosphorylation NHTKQDRyLFLFDKV P52735 T575-p Phosphorylation VIPPCKFtsPADLDA P52735 S576-p Phosphorylation IPPCKFtsPADLDAs P52735 S583-p Phosphorylation sPADLDAsGAGPGPK P52735 S626-p Phosphorylation LLRGDPEsPWWEGRL P52735 S639-p Phosphorylation RLVQTRKsGYFPSSS P52735 S663-p Phosphorylation PPISRPPsREIDYTA P52735 S778-p Phosphorylation ERSASRAssRSPASC P52735 S779-p Phosphorylation RSASRAssRSPASCA P52735 S836-p Phosphorylation ARDMRELsLREGDVV

PTM - dbPTM UniProt ID Position Code Type Resources References P52735 142 Y Phosphorylation Swiss-Prot 1010711 12454019;17389395 P52735 159 Y Phosphorylation Swiss-Prot 1010711 12454019 P52735 172 Y Phosphorylation Swiss-Prot 1010711 12454019 P52735 576 S Phosphorylation Swiss-Prot 1010711 18691976;19413330 P52735 626 S Phosphorylation Swiss-Prot 1010711 18691976 P52735 576 S Phosphorylation PhosphoELM.10011 18669648 P52735 779 S Phosphorylation PhosphoELM.10011 18669648 P52735 781 S Phosphorylation PhosphoELM.10011 18669648 P52735 575 T Phosphorylation PhosphoELM.10011 18669648 P52735 142 Y Phosphorylation PhosphoELM.10011 12454019;12454019 P52735 159 Y Phosphorylation PhosphoELM.10011 12454019;12454019 P52735 172 Y Phosphorylation PhosphoELM.10011 12454019;12454019 P52735 576 S Phosphorylation Phosphositeplus.1010730 16964243;18669648;18691976;20068231 P52735 626 S Phosphorylation Phosphositeplus.1010730 18691976 P52735 575 T Phosphorylation Phosphositeplus.1010730 16964243 P52735 142 Y Phosphorylation Phosphositeplus.1010730 12454019;17016520;17389395;18083107;18180459 P52735 159 Y Phosphorylation Phosphositeplus.1010730 12454019 P52735 172 Y Phosphorylation Phosphositeplus.1010730 12454019 P52735 769 S Phosphorylation HPRD 9.0 17081983,18669648,18691976,19651622,20068231 P52735 142 Y Phosphorylation (EGFR) HPRD 9.0 12454019,17389395,17016520 P52735 159 Y Phosphorylation (EGFR) HPRD 9.0 11516622,12454019 P52735 172 Y Phosphorylation (EGFR) HPRD 9.0 12454019 P52735 769 S Phosphorylation SysPTM 1.1 17081983 P52735 576 S Phosphorylation SysPTM 1.1 16964243;18691976 P52735 626 S Phosphorylation SysPTM 1.1 18691976 P52735 575 T Phosphorylation SysPTM 1.1 16964243

PTM - HPRD Symbol Position Code Type References VAV2 142 Y Phosphorylation 12454019,17389395,17016520 VAV2 159 Y Phosphorylation 11516622,12454019 VAV2 172 Y Phosphorylation 12454019 VAV2 565 T Phosphorylation 18669648,18691976 VAV2 566 S Phosphorylation 18669648,19413330,18691976,20068231 VAV2 616 S Phosphorylation 18691976 VAV2 768 S Phosphorylation 17081983,18691976,20166139 VAV2 769 S Phosphorylation 17081983,18669648,18691976,19651622,20068231 VAV2 771 S Phosphorylation 18669648,18691976,19651622,20166139,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type P52735 575 T 18669648 HTP Phosphorylation P52735 576 S 18669648 HTP Phosphorylation P52735 779 S 18669648 HTP Phosphorylation P52735 172 Y 12454019 EGFR LTP Phosphorylation P52735 172 Y 12454019 Lck LTP Phosphorylation P52735 781 S 18669648 HTP Phosphorylation P52735 142 Y 12454019 EGFR LTP Phosphorylation P52735 142 Y 12454019 Lck LTP Phosphorylation P52735 159 Y 12454019 EGFR LTP Phosphorylation P52735 159 Y 12454019 Lck LTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs P52735 142 Phosphotyrosine; by EGFR 12454019 P52735 159 Phosphotyrosine; by EGFR 12454019 P52735 172 Phosphotyrosine; by EGFR 12454019 P52735 576 Phosphoserine 20068231 P52735 583 Phosphoserine 24275569 P52735 626 Phosphoserine 18691976

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type VAV2 IPI00004977 S 566 PPCKFTpSPADLDA phosphorylation VAV2 IPI00004977 S 616 LRGDPEpSPWWEGR phosphorylation VAV2 IPI00004977 S 769 SASRASpSRSPVFT phosphorylation VAV2 IPI00004977 S 771 SRASSRpSPVFTPR phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 7410 113253 - K Ubiquitination 20940296