PTM - CPLM Gene Name UniProt ID Type Position Code UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 Ubiquitination 46 K UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 Ubiquitination 59 K UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 Ubiquitination 62 K UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 Ubiquitination 87 K UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 Ubiquitination 21 K

PTM - dbPAF Gene Name UniProt ID Position Type Species UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 101 T Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 114 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 122 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 138 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 139 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 16 T Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 19 T Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 191 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 270 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 274 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 279 Y Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 286 Y Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 287 T Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 308 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 315 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 316 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 317 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 318 S Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 84 T Homo sapiens(Human) UBQLN4; C1orf6; CIP75; UBIN Q9NRR5 98 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9NRR5 K62-ac Acetylation IFAGkILkDGDTLNQ Q9NRR5 R263-m1 Methylation AMMQEMMrNQDrALs Q9NRR5 R267-m1 Methylation EMMrNQDrALsNLEs Q9NRR5 R283-m1 Methylation PGGyNALrRMYtDIQ Q9NRR5 T16-p Phosphorylation TRPPIRVtVKtPkDk Q9NRR5 T19-p Phosphorylation PIRVtVKtPkDkEEI Q9NRR5 S42-p Phosphorylation KEFKEEIsRRFkAQQ Q9NRR5 T84-p Phosphorylation TVHLVIKtPQkAQDP Q9NRR5 S98-p Phosphorylation PAAATASsPSTPDPA Q9NRR5 S114-p Phosphorylation APSTTPAsPATPAQP Q9NRR5 S138-p Phosphorylation AGSGSRRssGGGPSP Q9NRR5 S139-p Phosphorylation GSGSRRssGGGPSPG Q9NRR5 S191-p Phosphorylation QMQRQLMsNPEMLSQ Q9NRR5 S270-p Phosphorylation rNQDrALsNLEsIPG Q9NRR5 S274-p Phosphorylation rALsNLEsIPGGyNA Q9NRR5 Y279-p Phosphorylation LEsIPGGyNALrRMY Q9NRR5 T287-p Phosphorylation NALrRMYtDIQEPMF Q9NRR5 S315-p Phosphorylation SLAGNSDsSSsQPLR Q9NRR5 S318-p Phosphorylation GNSDsSSsQPLRTEN Q9NRR5 K23-sm Sumoylation tVKtPkDkEEIVICD Q9NRR5 K21-ub Ubiquitination RVtVKtPkDkEEIVI Q9NRR5 K23-ub Ubiquitination tVKtPkDkEEIVICD Q9NRR5 K46-ub Ubiquitination EEIsRRFkAQQDQLV Q9NRR5 K59-ub Ubiquitination LVLIFAGkILkDGDT Q9NRR5 K62-ub Ubiquitination IFAGkILkDGDTLNQ Q9NRR5 K87-ub Ubiquitination LVIKtPQkAQDPAAA

PTM - dbPTM UniProt ID Position Code Type Resources References Q9NRR5 2 A Acetylation Swiss-Prot 1010711 19413330 Q9NRR5 318 S Phosphorylation Swiss-Prot 1010711 17525332 Q9NRR5 318 S Phosphorylation PhosphoELM.10011 17525332 Q9NRR5 46 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9NRR5 59 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9NRR5 62 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9NRR5 87 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9NRR5 114 S Phosphorylation Phosphositeplus.1010730 19664995 Q9NRR5 318 S Phosphorylation Phosphositeplus.1010730 17525332 Q9NRR5 98 S Phosphorylation Phosphositeplus.1010730 20068231 Q9NRR5 16 T Phosphorylation Phosphositeplus.1010730 20068231 Q9NRR5 279 Y Phosphorylation Phosphositeplus.1010730 20068231;21406692 Q9NRR5 286 Y Phosphorylation Phosphositeplus.1010730 18083107 Q9NRR5 98 S Phosphorylation HPRD 9.0 20068231 Q9NRR5 114 S Phosphorylation HPRD 9.0 19664995 Q9NRR5 318 S Phosphorylation HPRD 9.0 17525332 Q9NRR5 16 T Phosphorylation HPRD 9.0 20068231 Q9NRR5 101 T Phosphorylation HPRD 9.0 20068231

PTM - HPRD Symbol Position Code Type References UBQLN4 101 T Phosphorylation 20068231 UBQLN4 114 S Phosphorylation 19664995 UBQLN4 16 T Phosphorylation 20068231 UBQLN4 318 S Phosphorylation 17525332 UBQLN4 98 S Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9NRR5 318 S 17525332 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9NRR5 98 Phosphoserine 20068231 Q9NRR5 287 Phosphothreonine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type UBQLN4 IPI00024502 S 98 AAATASpSPSTPDP phosphorylation UBQLN4 IPI00024502 T 101 TASSPSpTPDPASA phosphorylation UBQLN4 IPI00477826 T 203 GWKWKLpTGADARS phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 56893 121223 - K Ubiquitination 21139048 56893 121223 - K Ubiquitination 21890473 56893 121223 - K Ubiquitination 21906983 56893 121223 - K Ubiquitination 21963094 56893 121223 - K Ubiquitination 23000965

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID UBQLN4 Homo sapiens (Human) 87; 59; 46; 62 "87,VIKTPQKAQDPAA; 59,VLIFAGKILKDGD; 46,EISRRFKAQQDQL; 62,FAGKILKDGDTLN" "87:21906983; 59:21906983,21890473; 46:21906983,21890473; 62:21906983" UBQLN4 Homo sapiens (Human) 87; 59; 46; 62 "87,VIKTPQKAQDPAA; 59,VLIFAGKILKDGD; 46,EISRRFKAQQDQL; 62,FAGKILKDGDTLN" "87:21906983; 59:21890473,21906983; 46:21890473,21906983; 62:21906983" UBQLN4 Homo sapiens (Human) 59; 46 "59,VLIFAGKILKDGD; 46,EISRRFKAQQDQL" 59:21890473; 46:21890473 UBQLN4 Homo sapiens (Human) 59; 58; 46; 45 "59,VLIFAGKILKDGD; 58,VLIFAGKILKDGD; 46,EISRRFKAQQDQL; 45,EISRRFKAQQDQL" "59:21906983,21890473; 46:21906983,21890473; 62:21906983" UBQLN4 Homo sapiens (Human) 59; 46 "59,VLIFAGKILKDGD; 46,EISRRFKAQQDQL" 59:21890473; 46:21890473