PTM - CPLM Gene Name UniProt ID Type Position Code TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Acetylation 252 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Acetylation 763 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Acetylation 769 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Acetylation 951 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Acetylation 953 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Sumoylation 776 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Ubiquitination 394 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Ubiquitination 329 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Ubiquitination 378 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Ubiquitination 305 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Ubiquitination 951 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Ubiquitination 334 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Ubiquitination 1033 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Ubiquitination 389 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Ubiquitination 376 K TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 Ubiquitination 1057 K

PTM - dbPAF Gene Name UniProt ID Position Type Species TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 1004 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 1048 Y Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 1051 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 1085 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 1102 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 1105 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 1119 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 505 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 524 Y Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 622 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 643 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 644 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 646 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 658 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 659 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 661 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 663 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 738 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 744 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 747 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 767 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 781 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 787 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 789 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 803 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 808 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 809 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 812 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 813 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 815 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 819 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 820 T Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 852 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 855 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 856 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 862 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 949 S Homo sapiens(Human) TRIM33; KIAA1113; RFG7; TIF1G Q9UPN9 959 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9UPN9 K252-ac Acetylation HQRVKFTkDHLIRKK Q9UPN9 K763-ac Acetylation SSGRTAEkTSLsFkS Q9UPN9 K769-ac Acetylation EkTSLsFkSDQVKVk Q9UPN9 K776-ac Acetylation kSDQVKVkQEPGTED Q9UPN9 K793-ac Acetylation CsFsGGVkQEKTEDG Q9UPN9 K861-ac Acetylation LssLVNGksPIRSLM Q9UPN9 K950-ac Acetylation CDNLQHskkGkTAQG Q9UPN9 K951-ac Acetylation DNLQHskkGkTAQGL Q9UPN9 K953-ac Acetylation LQHskkGkTAQGLsP Q9UPN9 K1127-ac Acetylation DERPVHIk_______ Q9UPN9 R440-m1 Methylation RLITFQLrHILKARC Q9UPN9 R458-m1 Methylation PAANGAIrFHCDPTF Q9UPN9 R515-m1 Methylation QINLAQLrLQHMQQQ Q9UPN9 R515-m2 Methylation QINLAQLrLQHMQQQ Q9UPN9 R535-m1 Methylation HQQLQQMrMQQPPAP Q9UPN9 R555-m1 Methylation TTTQQHPrQAAPQML Q9UPN9 R577-m2 Methylation ISVQTMQrGNMNCGA Q9UPN9 R591-m2 Methylation AFQAHQMrLAQNAAr Q9UPN9 R591-m1 Methylation AFQAHQMrLAQNAAr Q9UPN9 R598-m2 Methylation rLAQNAArIPGIPrH Q9UPN9 R604-m2 Methylation ArIPGIPrHSGPQYS Q9UPN9 S169-p Phosphorylation SVPIPGGsNGDIQQV Q9UPN9 Y197-p Phosphorylation QIDLVDNyFVKDTSE Q9UPN9 T505-p Phosphorylation GTNHISKtPGQINLA Q9UPN9 Y524-p Phosphorylation QHMQQQVyAQKHQQL Q9UPN9 S622-p Phosphorylation PHLQRQHsNPGHAGP Q9UPN9 T643-p Phosphorylation HNTTINPtsPTTATM Q9UPN9 S644-p Phosphorylation NTTINPtsPTTATMA Q9UPN9 S661-p Phosphorylation NRGPTSPsVTAIELI Q9UPN9 S727-p Phosphorylation SPGPSALsPGSSGLS Q9UPN9 S744-p Phosphorylation HTPVRPPsTSsTGSR Q9UPN9 S747-p Phosphorylation VRPPsTSsTGSRGSC Q9UPN9 S767-p Phosphorylation TAEkTSLsFkSDQVK Q9UPN9 S787-p Phosphorylation GTEDEICsFsGGVkQ Q9UPN9 S789-p Phosphorylation EDEICsFsGGVkQEK Q9UPN9 S803-p Phosphorylation KTEDGRRsACMLssP Q9UPN9 S808-p Phosphorylation RRsACMLssPEssLt Q9UPN9 S809-p Phosphorylation RsACMLssPEssLtP Q9UPN9 S812-p Phosphorylation CMLssPEssLtPPLs Q9UPN9 S813-p Phosphorylation MLssPEssLtPPLst Q9UPN9 T815-p Phosphorylation ssPEssLtPPLstNL Q9UPN9 S819-p Phosphorylation ssLtPPLstNLHLES Q9UPN9 T820-p Phosphorylation sLtPPLstNLHLESE Q9UPN9 S852-p Phosphorylation MNESCKQsGLssLVN Q9UPN9 S855-p Phosphorylation SCKQsGLssLVNGks Q9UPN9 S856-p Phosphorylation CKQsGLssLVNGksP Q9UPN9 S862-p Phosphorylation ssLVNGksPIRSLMH Q9UPN9 S949-p Phosphorylation DCDNLQHskkGkTAQ Q9UPN9 S959-p Phosphorylation GkTAQGLsPVDQRKC Q9UPN9 Y1048-p Phosphorylation MMKVVQVyADtQEIN Q9UPN9 T1051-p Phosphorylation VVQVyADtQEINLkA Q9UPN9 T1102-p Phosphorylation EEDDGEVtEDsDEDF Q9UPN9 S1105-p Phosphorylation DGEVtEDsDEDFIQP Q9UPN9 S1119-p Phosphorylation PRRKRLksDERPVHI Q9UPN9 K334-sm Sumoylation LAKLLEKkNYVHFAA Q9UPN9 K763-sm Sumoylation SSGRTAEkTSLsFkS Q9UPN9 K769-sm Sumoylation EkTSLsFkSDQVKVk Q9UPN9 K776-sm Sumoylation kSDQVKVkQEPGTED Q9UPN9 K793-sm Sumoylation CsFsGGVkQEKTEDG Q9UPN9 K861-sm Sumoylation LssLVNGksPIRSLM Q9UPN9 K953-sm Sumoylation LQHskkGkTAQGLsP Q9UPN9 K1007-sm Sumoylation PMDLSTVkKKLQKKH Q9UPN9 K1057-sm Sumoylation DtQEINLkADSEVAQ Q9UPN9 K1118-sm Sumoylation QPRRKRLksDERPVH Q9UPN9 K320-ub Ubiquitination EEAFQNQkGAIENLL Q9UPN9 K394-ub Ubiquitination VTKERQMkLLQQQND

PTM - dbPTM UniProt ID Position Code Type Resources References Q9UPN9 252 K Acetylation Swiss-Prot 1010711 19608861 Q9UPN9 505 T Phosphorylation Swiss-Prot 1010711 18220336 Q9UPN9 763 K Acetylation Swiss-Prot 1010711 19608861 Q9UPN9 769 K Acetylation Swiss-Prot 1010711 19608861 Q9UPN9 862 S Phosphorylation Swiss-Prot 1010711 18669648 Q9UPN9 953 K Acetylation Swiss-Prot 1010711 19608861 Q9UPN9 1102 T Phosphorylation Swiss-Prot 1010711 18669648 Q9UPN9 1105 S Phosphorylation Swiss-Prot 1010711 18669648 Q9UPN9 1119 S Phosphorylation Swiss-Prot 1010711 18669648 Q9UPN9 862 S Phosphorylation PhosphoELM.10011 18669648 Q9UPN9 1105 S Phosphorylation PhosphoELM.10011 18669648 Q9UPN9 1119 S Phosphorylation PhosphoELM.10011 18669648 Q9UPN9 505 T Phosphorylation PhosphoELM.10011 18220336 Q9UPN9 1102 T Phosphorylation PhosphoELM.10011 18669648 Q9UPN9 829 D Caspase Phosphositeplus.1010730 18722006 Q9UPN9 776 K Sumoylation Phosphositeplus.1010730 20797634 Q9UPN9 394 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9UPN9 252 K Acetylation Phosphositeplus.1010730 19608861 Q9UPN9 763 K Acetylation Phosphositeplus.1010730 19608861 Q9UPN9 769 K Acetylation Phosphositeplus.1010730 19608861 Q9UPN9 953 K Acetylation Phosphositeplus.1010730 19608861 Q9UPN9 1105 S Phosphorylation Phosphositeplus.1010730 18669648;19415658;20068231;20363803;20393185;21406692 Q9UPN9 1119 S Phosphorylation Phosphositeplus.1010730 18669648;20068231;20363803;20393185;20736484;21406692 Q9UPN9 856 S Phosphorylation Phosphositeplus.1010730 21659604 Q9UPN9 862 S Phosphorylation Phosphositeplus.1010730 18669648;20068231;21406692;21659604;22115753 Q9UPN9 1102 T Phosphorylation Phosphositeplus.1010730 18669648;19415658;20068231;20363803;20393185;21406692 Q9UPN9 505 T Phosphorylation Phosphositeplus.1010730 18220336 Q9UPN9 252 K Acetylation HPRD 9.0 19608861 Q9UPN9 763 K Acetylation HPRD 9.0 19608861 Q9UPN9 769 K Acetylation HPRD 9.0 19608861 Q9UPN9 951 K Acetylation HPRD 9.0 19608861 Q9UPN9 953 K Acetylation HPRD 9.0 19608861 Q9UPN9 622 S Phosphorylation HPRD 9.0 20068231 Q9UPN9 862 S Phosphorylation HPRD 9.0 17322306,18669648,18767875,20068231 Q9UPN9 1105 S Phosphorylation HPRD 9.0 18669648,19415658,18452278,20068231 Q9UPN9 1119 S Phosphorylation HPRD 9.0 18669648,19651622,18767875,20068231 Q9UPN9 643 T Phosphorylation HPRD 9.0 20068231 Q9UPN9 1085 T Phosphorylation HPRD 9.0 18669648,19415658,18452278,20068231 Q9UPN9 1102 T Phosphorylation HPRD 9.0 18669648,19415658,18452278,20068231 Q9UPN9 862 S Phosphorylation SysPTM 1.1 17322306;18669648 Q9UPN9 1105 S Phosphorylation SysPTM 1.1 18669648 Q9UPN9 1119 S Phosphorylation SysPTM 1.1 18669648 Q9UPN9 1102 T Phosphorylation SysPTM 1.1 18669648

PTM - HPRD Symbol Position Code Type References TRIM33 1085 T Phosphorylation 18669648,19415658,18452278,20068231 TRIM33 1088 S Phosphorylation 18669648,19415658,18452278,20068231 TRIM33 1102 S Phosphorylation 18669648,19651622,18767875,20068231 TRIM33 1102 T Phosphorylation 18669648,19415658,18452278,20068231 TRIM33 1105 S Phosphorylation 18669648,19415658,18452278,20068231 TRIM33 1119 S Phosphorylation 18669648,19651622,18767875,20068231 TRIM33 252 K Acetylation 19608861 TRIM33 622 S Phosphorylation 20068231 TRIM33 643 T Phosphorylation 20068231 TRIM33 763 K Acetylation 19608861 TRIM33 769 K Acetylation 19608861 TRIM33 862 S Phosphorylation 17322306,18669648,18767875,20068231 TRIM33 951 K Acetylation 19608861 TRIM33 953 K Acetylation 19608861

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9UPN9 1119 S 18669648 HTP Phosphorylation Q9UPN9 862 S 18669648 HTP Phosphorylation Q9UPN9 1105 S 18669648 HTP Phosphorylation Q9UPN9 1102 T 18669648 HTP Phosphorylation Q9UPN9 505 T 18220336 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9UPN9 515 Asymmetric dimethylarginine; alternate 24129315 Q9UPN9 515 Omega-N-methylarginine; alternate 24129315 Q9UPN9 535 Omega-N-methylarginine 24129315 Q9UPN9 577 Asymmetric dimethylarginine 24129315 Q9UPN9 591 Omega-N-methylarginine; alternate 24129315 Q9UPN9 598 Asymmetric dimethylarginine 24129315 Q9UPN9 604 Asymmetric dimethylarginine 24129315 Q9UPN9 763 N6-acetyllysine; alternate 19608861 Q9UPN9 769 N6-acetyllysine; alternate 19608861 Q9UPN9 862 Phosphoserine 18669648;20068231;21406692;23186163 Q9UPN9 953 N6-acetyllysine; alternate 19608861 Q9UPN9 1051 Phosphothreonine 23186163 Q9UPN9 1102 Phosphothreonine 18669648;20068231;21406692 Q9UPN9 1105 Phosphoserine 18669648;20068231;21406692 Q9UPN9 1119 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type TRIM33 IPI00010252 K 252 QRVKFTaKDHLIRK acetylation TRIM33 IPI00010252 K 763 SGRTAEaKTSLSFK acetylation TRIM33 IPI00010252 K 769 KTSLSFaKSDQVKV acetylation TRIM33 IPI00010252 K 951 NLQHSKaKGKTAQG acetylation TRIM33 IPI00010252 K 953 QHSKKGaKTAQGLS acetylation TRIM33 IPI00010252 S 1105 GEVTEDpSDEDFIQ phosphorylation TRIM33 IPI00010252 S 1119 RRKRLKpSDERPVH phosphorylation TRIM33 IPI00010252 S 622 HLQRQHpSNPGHAG phosphorylation TRIM33 IPI00010252 S 862 SLVNGKpSPIRSLM phosphorylation TRIM33 IPI00010252 T 1102 EDDGEVpTEDSDED phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 51592 119625 - K Sumoylation 21693764 51592 119625 - K Ubiquitination 21139048 51592 119625 - K Ubiquitination 21890473 51592 119625 - K Sumoylation 19471022 51592 119625 - K Sumoylation 21252943 51592 119625 - K Ubiquitination 21963094 51592 119625 - K Ubiquitination 23000965 51592 119625 - K Sumoylation 23788427 51592 119625 - K Sumoylation 24654937 51592 119625 - K Sumoylation 25027693 51592 119625 - K Sumoylation 25410875

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID TRIM33 Homo sapiens (Human) 394 "394,TKERQMKLLQQQN" 394:21890473 TRIM33 Homo sapiens (Human) 394 "394,TKERQMKLLQQQN" 394:21890473