PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TRIM16 TERF1 21044950 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 MOV10 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G TRIM16 MCM7 22863883 biogrid exp GP GP G G GP G G G GP G G G G GP G GP G GP G G GP GP GP G GP G GP GP G TRIM16 NXF1 22658674 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 APP 21832049 biogrid exp G GP G G GP GP G G GP G G G G G G GP GP G GP G GP GP G G GP G G GP G CLUH TRIM16 22863883 biogrid exp G G G G G GP G GP GP G GP G GP G G GP GP G G G GP G G GP GP G GP G G TRIM16 TOMM34 22863883 biogrid exp G GP G G G G G G GP G G G G G G GP G GP GP G GP G G G GP G G GP G TRIM16 TINF2 21044950 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 SETDB1 16169070 hprd,i2d,mint,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G G GP GP G GP GP G TRIM16 POT1 21044950 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 E2F1 20729920 biogrid,i2d,intact exp P GP G G GP GP G GP GP G GP GP GP GP GP GP GP GP G P P GP P GP P GP GP G TRIM16 TRIM16L 26186194 biogrid exp G GP G G G G GP GP G G G G G TRIM16 ACD 21044950 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G TRIM16 VIM 20729920 biogrid,i2d,intact exp GP GP G G GP GP G G GP G GP GP GP GP G G GP GP GP G G G G G G GP G GP G TRIM16 YWHAE ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 IKZF2 23023127 pred P P G G G P P P P P P GP G P P P P G GP GP GP GP GP GP P P TRIM16 GRB10 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 NOX5 23023127 pred P GP G GP G G P G GP P P P G GP G P GP GP GP G P GP G TRIM16 BMPR1A 23023127 pred GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TRIM16 TRADD 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G G GP G G G GP GP GP G G GP GP GP G TRIM16 BRD8 23023127 pred P P G GP P P P P P P P P P GP P P P P P P GP TRIM16 PCGF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TNFSF15 TRIM16 23023127 pred GP GP G GP P G P GP GP P GP GP G GP GP P P G GP G GP P GP P GP P TRIM16 ELANE 23023127 pred G GP G G TRIM16 CASP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TRIM16 CCL5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 INSR 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SOCS2 TRIM16 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 BMP2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 CMA1 23023127 pred G G GP G P G G TRIM16 VEZF1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 PYCARD 23023127 pred GP GP G G GP P G G GP G P GP GP GP G GP P GP GP G GP GP GP P GP GP GP P G TRIM16 IL20 23023127 pred G P G G P GP P P GP P G P P GP G G GP GP GP GP G TRIM16 NLRP2 23023127 pred P P G P P G P GP G GP P GP GP G GP GP GP GP G GP GP GP P GP GP GP GP TRIM16 PRSS8 23023127 pred G G G P G P GP G G G G G P G G GP GP GP P G G GP G TRIM16 BRCA1 23023127 pred P P G GP P P P P P P P GP P P P P P P P P P P GP TRIM16 RXRA 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 NOD2 23023127 pred P G GP P P P GP P P P P P P P P P GP P TP73 TRIM16 23023127 pred G G G G G TRIM16 GH1 23023127 pred G G G G G G GP GP CUBN TRIM16 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 SMAD3 23023127 pred GP GP G G G GP G G G G G G GP GP G G GP G GP G GP G G G G G G G G TRIM16 HGF 23023127 pred GP GP G G GP P G GP GP GP GP GP GP G P GP GP GP G GP GP P GP P GP GP P G TRIM16 RBM14 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 SORBS1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G TRIM16 VEGFC 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DVL2 TRIM16 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 TRIM28 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 TNC 23023127 pred GP GP G G G GP G G GP G GP G G G GP GP G GP GP GP G GP G GP GP G TRIM16 CX3CL1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 MBD3 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G CIDEA TRIM16 23023127 pred G G G G G G G G TRIM16 KAT6A 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 CTCF 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 PTGES3 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TRIM16 IKZF1 23023127 pred G G G G GP G G G G G G G GP G G G G G G G G G G G GP G G G TRIM16 GHR 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 JADE2 23023127 pred G GP G G G GP G G GP G G G G G G GP GP GP G G GP GP G GP GP G G G G TRIM16 TGFB1 23023127 pred G G G G GP G G G G G G G G G G GP G G G G GP G G GP GP GP G G TRIM16 NGFR 23023127 pred GP G G P P G G G G G G P G G G TRIM16 CARD8 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 SLA2 23023127 pred G G G G G G G G G G G G G G G G TRIM16 STAT3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 HOXA7 23023127 pred G G G G G G G G G G G G G G G G G G TRIM16 INS 23023127 pred G GP G TRIM16 CD40 23023127 pred G G G G G G G G G G G G G GP G G G G G G G G G G G GP G G G TRIM16 NOTCH4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 PANX1 23023127 pred G GP G G GP GP G GP P G GP G GP G G P GP GP GP G GP G G GP GP GP GP GP G TRIM16 RING1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 RBP4 23023127 pred G G G G G G G GP GP G G G G G GP G G G G G G P TRIM16 TFRC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G G GP G GP GP G TRIM16 INPP5D 23023127 pred G GP G G GP GP G GP G G GP G G GP G G GP GP G G G G GP GP G GP G G G TRIM16 ATP7A 23023127 pred GP GP G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 TGFB3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G G GP GP GP GP GP GP GP G TRIM16 CRTAM 23023127 pred P P P GP P P P P GP P P GP P P P P P P P G P P TRIM16 TCHH 23023127 pred P P P P P P P P P P P P P GP P P P P P P TRIM16 SHC1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 CHIA 23023127 pred P P G G P G GP P P GP GP P G GP GP GP G P P P G P P GP P G TRIM16 IL27RA 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 KLRK1 23023127 pred P P P TRIM16 NLRP3 23023127 pred P G GP P P P P P P P P TRIM16 DMBT1 23023127 pred G G G G G G G G GP G GP G GP G G GP G G G G G G GP G GP G GP G G TRIM16 IFNAR1 23023127 pred GP GP G G GP GP G GP P G GP GP GP GP G GP GP GP GP G GP GP GP G P GP GP TRIM16 FLG 23023127 pred GP TRIM16 NOTCH1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 MICB 23023127 pred G G G G G G G G G G G G G G G G G G G G G TRIM16 KMT2A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MID1 TRIM16 23023127 pred G G G GP G GP GP G GP G G G G GP GP G GP G GP G G GP GP G GP GP G TRIM16 GATA5 23023127 pred G G G G G TRIM16 GRB14 23023127 pred P GP P P G GP GP GP G P GP P P G GP GP P P GP P P GP TRIM16 IRF4 23023127 pred G G G G GP G G G G G G GP GP GP G G G G G G G G G G G GP G G G TRIM16 VEGFA 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 TP63 23023127 pred GP G G G G G G G G G G G G G G G G G G GP GP G G G G G TRIM16 TNFRSF1A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 MALT1 23023127 pred G G GP G G G G G G GP G G G G G G G G G G G G GP G TRIM16 F7 23023127 pred P GP G G GP GP G GP GP G GP GP GP GP G P GP G GP G GP P GP GP GP G GP GP G TNFSF14 TRIM16 23023127 pred GP P P P P P P GP GP G P P G P P P P P G P P TRIM16 FADD 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP G GP GP GP GP GP GP G TRIM24 TRIM16 23023127 pred G G G G G G G G GP G G G GP GP G GP G GP G G GP GP GP GP GP G GP GP G TRIM16 BPTF 23023127 pred G GP G G G GP G G GP G GP GP GP G G GP GP GP G G GP G GP G GP G GP GP G TRIM16 NEDD4 23023127 pred GP GP G GP P G GP GP GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G TRIM16 BRD1 23023127 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G G GP G TRIM16 TAB2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 CDKN2B 23023127 pred GP P GP P P G G GP P G P GP G TRIM16 SP100 23023127 pred GP GP G GP P G GP GP GP GP GP GP G GP P GP P G GP GP GP GP GP GP GP P G TRIM16 TRIM68 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TRIM16 TP53 23023127 pred G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G TRIM16 SDC1 23023127 pred GP GP G G GP G G G GP G GP G G GP G GP G G GP G GP G GP G GP G GP GP G TRIM16 RNF6 23023127 pred G GP G G GP GP G G GP G GP G GP G G GP GP G G G GP G G G GP GP GP GP G TRIM16 PYDC1 23023127 pred G TRIM16 CADM1 23023127 pred GP GP G GP G G GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G TRIM16 OSR1 23023127 pred G P GP GP P GP G G P P G G P P GP G TRIM16 CREBBP 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 TGFBR1 23023127 pred GP G G G GP GP G GP GP G GP GP GP G G GP GP G G G G G G G GP G GP G G TRIM16 FLT1 23023127 pred G G G GP G GP GP G G G G G G G GP G G G GP G G GP G G G G G TRIM16 LTBP2 23023127 pred GP GP G G G G G G G G GP G GP G G GP G GP GP G GP GP G G GP G GP G G TRIM16 EP300 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 HRNR 23023127 pred P P P P P P P P P P P P P P P P P P P P TRIM16 S100A7 23023127 pred GP G TRIM38 TRIM16 23023127 pred GP GP G GP P G GP GP GP GP GP GP G GP GP GP GP GP GP GP GP GP GP GP P G TRAF3IP2 TRIM16 23023127 pred GP GP P P G P GP GP GP GP GP G GP P GP GP G GP GP GP P GP GP GP P G TRIM16 UACA 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP G GP G GP GP GP G GP G GP GP G LGALS9 TRIM16 23023127 pred GP GP G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP P GP GP GP P TRIM16 SYK 23023127 pred GP G G G GP GP G GP G GP G GP GP G GP GP GP G G G G G GP GP GP GP G TRIM16 APC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP TRIM16 TRIM36 23023127 pred G GP G P GP G P P GP GP P G GP P GP TRIM16 IRF9 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TRIM16 TNF 23023127 pred G G G G G GP G G GP G G G GP G GP GP G GP G G G G GP G GP G G TRIM16 NECAB3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 GRIP1 23023127 pred P P G P GP G P GP G GP P P P G P GP P G GP GP GP P P GP GP P TRIM16 KEAP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 TNFSF13B 23023127 pred GP GP G G GP GP G GP GP G P GP GP GP G GP GP P GP GP GP GP P GP GP GP P G TRIM16 ESR1 23023127 pred GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 IL2 23023127 pred P P P P P P P P P P P P P P P P P P P TRIM16 CALR 23023127 pred GP G G G GP GP G G G G G GP GP GP G GP GP G GP G GP GP G G GP GP GP GP G TRIM16 RNF4 23023127 pred GP G G G G GP G GP GP G GP G G G G G GP GP G G GP GP GP GP G G GP GP G TRIM16 PDGFA 23023127 pred GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G TRIM16 ZEB1 23023127 pred P P P P P P P P P P P TRIM16 TRIM25 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TRIM16 IGFBP7 23023127 pred G G G G G G G G G G GP G G G G G G G GP G G G G G G G G GP G TRIM16 EZH2 23023127 pred GP P G GP GP P GP G GP G P P P GP GP GP GP TRIM16 NLRP12 23023127 pred GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP P APBB1 TRIM16 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G G GP G GP G GP GP GP GP G GP GP GP G TRIM16 NLRC4 23023127 pred P P G GP P P P P P GP P P P P P P P G P P TRIM16 CD3E 23023127 pred G G G GP G G G G G G G G GP G G G G G G G G G G G GP G G TRIM16 TNFSF4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP P GP GP P G P GP GP GP GP G GP GP G TRIM16 BRPF1 23023127 pred GP GP G G GP GP G GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 EVPL 23023127 pred GP G G GP G P P G GP G G TRIM16 NCOA2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 KAT2A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP GP GP GP G TRIM16 TGFB2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM13 TRIM16 23023127 pred GP GP G G G GP G G GP G G GP GP G G GP GP G G G G GP G GP GP G GP GP G TRIM16 PIK3R1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 AZU1 23023127 pred G GP P P P P P P P P P P G TRIM16 CD4 23023127 pred G G G G GP G G G G G G G G GP G G G G G G G G G G G GP G G G TRIM16 STXBP4 23023127 pred P GP G GP P P P GP P P P G P P GP GP G GP GP P P GP P P P G TRIM16 FST 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 TIGIT 23023127 pred G G G G G G G G G TRIM16 CD38 23023127 pred G G G GP G G G G G GP G G G G G GP G G G GP G JAK2 TRIM16 23023127 pred G GP G G GP GP G GP GP G GP P GP GP G P GP GP P P G GP G GP GP GP GP TRIM16 S100A13 23023127 pred GP GP G G G GP G GP G G GP G GP GP G G GP GP GP G GP G G GP G GP G GP G TRIM16 BTG1 23023127 pred GP GP G G GP GP G GP G G GP GP GP G G GP GP G GP G GP GP G GP GP G GP GP G TRIM16 FOXP3 23023127 pred G G G P P G G G P P TRIM16 KAT6B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TNFRSF10B TRIM16 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM16 RNF135 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G SH2B2 TRIM16 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP G GP G GP GP GP G GP GP GP GP G TRIM16 KMT2E 23023127 pred G G G G GP G G G G G G G G G G G G G G G G G G G G G G GP G TRIM16 IGFBP2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM16 EGF 23023127 pred P P P P GP P GP P P P G P P GP P GP GP GP GP P P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O95361 P54274-2 two hybrid 21044950 direct interaction X 2 O95361 two hybrid 21044950 direct interaction X 2 O95361 Q9NUX5-2 two hybrid 21044950 direct interaction X 2 O95361 P05067-7 pull down 21832049 direct interaction X 2 O95361 C6EMX8 biochemical 22863883 colocalization X 2 O95361 Q01094 affinity chromatography technology 20729920 physical association X 2 P0CG48 O95361 affinity chromatography technology 21963094 physical association X 2 P08670 O95361 affinity chromatography technology 20729920 physical association X 2 O95361 Q96AP0-2 two hybrid 21044950 direct interaction X 2 Q15785 O95361 biochemical 22863883 colocalization X 2 O75153 O95361 biochemical 22863883 colocalization X 2 O95361 Q15047-3 two hybrid 16169070 - X 2 O95361 Q15047-3 two hybrid 16169070 - X 2 O95361 Q01094 anti tag coimmunoprecipitation 20729920 physical association X 2 O95361 Q01094 anti tag coimmunoprecipitation 20729920 physical association X 2 P08670 O95361 anti bait coimmunoprecipitation 20729920 physical association X 2 P08670 O95361 anti bait coimmunoprecipitation 20729920 physical association X 2 P08670 O95361 confocal microscopy 20729920 colocalization X 2 O95361 Q15047 two hybrid pooling approach 16169070 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B TRIM16 UBC MI:0004(affinity chromatography technology) 21963094 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_264438 prey bait TRIM16 ACD MI:0018(two hybrid) 21044950 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_198507 prey bait TRIM16 TINF2 MI:0018(two hybrid) 21044950 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_198449 prey bait TRIM16 VIM MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 20729920 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(intact)|(intact) UniProt_108959|BIOGRID_185078|UniProt_108955|UniProt_108956 neutral component|prey|bait|bait neutral component|bait|prey|prey TRIM16 MCM7 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301093 bait prey KIAA0664 TRIM16 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_300731 prey bait TRIM16 E2F1 MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 20729920 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_185079|UniProt_108957|UniProt_108958 bait|bait|bait prey|prey|prey TRIM16 TERF1 MI:0018(two hybrid) 21044950 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_198242 prey bait TRIM16 POT1 MI:0018(two hybrid) 21044950 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_198642 prey bait TRIM16 APP MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_229371 bait prey TRIM16 SETDB1 MI:0492(in vitro)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|MI:0471(mint)|(intact)|MI:0471(mint) HPRD_29560|MINT_62390|UniProt_157219|MINT_33449 -|bait|bait|bait -|prey|prey|prey TRIM16 TOMM34 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304408 bait prey

PPI - HINT Gene A Gene B PMID Method Quality CLUH TRIM16 22863883 0401 HT TRIM16 MCM7 22863883 0401 HT TRIM16 TOMM34 22863883 0401 HT TRIM16 TRIM16L 26186194 0004 HT CLUH TRIM16 22863883 0401 HT TRIM16 MCM7 22863883 0401 HT TRIM16 TOMM34 22863883 0401 HT TRIM16 TRIM16L 26186194 0004 HT CLUH TRIM16 22863883 0401 LC TRIM16 MCM7 22863883 0401 LC TRIM16 TERF1 21044950,21044950 0809,0018 HT TRIM16 SETDB1 16169070,16169070 0018,0398 HT TRIM16 TOMM34 22863883 0401 LC TRIM16 ACD 21044950,21044950 0809,0018 HT TRIM16 TINF2 21044950,21044950,21044950 0809,0018,0096 HT TRIM16 POT1 21044950,21044950 0809,0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9HCE1 O95361 MOV10 TRIM16 0.126 22658674 Q9NUX5 O95361 POT1 TRIM16 0.183 21044950 P08670 O95361 VIM TRIM16 0.21 20729920 O95361 O75153 TRIM16 CLUH 0.081 22863883 P33993 O95361 MCM7 TRIM16 0.081 22863883 P05067 O95361 APP TRIM16 0.183 21832049 Q309B1 O95361 TRIM16L TRIM16 0.126 26186194 Q01094 O95361 E2F1 TRIM16 0.21 20729920 Q15785 O95361 TOMM34 TRIM16 0.081 22863883 Q9JK38 O95361 GNPNAT1 TRIM16 0.236 26496610 Q9QUI0 O95361 RHOA TRIM16 0.236 26496610 Q8CIF6 O95361 SIDT2 TRIM16 0.236 26496610 Q96AP0 O95361 ACD TRIM16 0.183 21044950 Q9BSI4 O95361 TINF2 TRIM16 0.183 21044950 Q9UBU9 O95361 NXF1 TRIM16 0.126 22658674 Q15047 O95361 SETDB1 TRIM16 0.126 16169070 P54274 O95361 TERF1 TRIM16 0.183 21044950

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 TRIM16 APP MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 VIM MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 UBC MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 TERF1 MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 RHOA MI:0362 inference MI:0461 interaction database TRIM16 UFM1 MI:0362 inference MI:0461 interaction database TRIM16 E2F1 MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 SETDB1 MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 TRIM16L MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 SIDT2 MI:0362 inference MI:0461 interaction database TRIM16 ACD MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 GNPNAT1 MI:0362 inference MI:0461 interaction database TRIM16 TINF2 MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 MOV10 MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 POT1 MI:0045 experimental interaction detection MI:0461 interaction database TRIM16 NXF1 MI:0045 experimental interaction detection MI:0461 interaction database