PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Tcp1 Fbxl2 21343341 biogrid exp Ccnd3 Fbxl2 22024926,22020328 biogrid exp Calm1, Calm2, Calm3 Fbxl2 21343341 biogrid exp Fbxl2 Fbxo3 ortho Hsp90ab1 Fbxl2 ortho Aarsd1 Fbxl2 ortho Fbxl2 Sugt1 ortho Ube2d3 Fbxl2 ortho Fbxl2 Cdc34 ortho Fbxl2 Hacd3 ortho Ube2g1 Fbxl2 ortho Ube2d1 Fbxl2 ortho Fbxl2 Cul1 ortho Pik3r2 Fbxl2 ortho Fbxl2 Cul2 ortho Hsp90aa1 Fbxl2 ortho Fbxl2 Nlrp3 ortho Fbxl2 Skp1 ortho Rabggtb Fbxl2 ortho Aurkb Fbxl2 ortho Col7a1 Fbxl2 ortho App Fbxl2 ortho Ccnd2 Fbxl2 ortho Pik3r1 Fbxl2 ortho Ppp1cc Fbxl2 ortho Ptpn13 Fbxl2 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8BH16 P30282 affinity chromatography technology 22020328 physical association X 2 Q8BH16 P30282 enzymatic study 22020328 direct interaction X 2 Q8BH16 P30282 enzymatic study 22024926 direct interaction X 2 Q8BH16 P11983 affinity chromatography technology 21343341 physical association X 2 Q8BH16 P11983 enzymatic study 21343341 direct interaction X 2 Q8BH16 P11983 two hybrid 21343341 direct interaction X 2 Q8BH16 P62204 two hybrid 21343341 direct interaction X 2 Q8BH16 P11983 fluorescent resonance energy transfer 21343341 direct interaction X 2 Q8BH16 P62204 fluorescent resonance energy transfer 21343341 direct interaction X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8BH16 P11983 FBXL2 TCP1 0.74 21343341 Q8BH16 P62204 FBXL2 CALM3 0.523 21343341 Q8BH16 P30282 FBXL2 CCND3 0.623 22024926,22020328