PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ywhae Gga1 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Scg2 Gga1 16601685 biogrid exp P G G G G G G G G G G G G Cnst Gga1 19864490 intact exp App Gga1 17005855 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Synrg Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G UPF0500 protein C1orf216 homolog Gga1 ortho Gga1 Stab1 ortho GP G G G G G G G G G G G G G G G G G G G G Gga1 Necap2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G M6pr Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gga1 Bag3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G F8 Gga1 ortho G G G Gga1 Rnf11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jun Gga1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Igf2r Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps27a Gga1 ortho P Dtnb Gga1 ortho P G G G G G G G G G G G G G G G G G G G G Gga1 Gipc1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Gga1 Hgs ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Rabep1 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Gga1 Map1a ortho P Tmem17 Gga1 ortho Arf1 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gga1 Rabgef1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Arf3 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Smad3 Gga1 ortho G G G G G G G G G G G G G G G Lix1l Gga1 ortho Aftph Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Tsg101 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Stam Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gga1 Tollip ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdkl3 Gga1 ortho Sorl1 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Dnm2 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Arf6 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Akt2 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gga1 Bace2 ortho G G G G G G G G G Vcp Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif4ebp1 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G Gga3 Gga1 ortho Bace1 Gga1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Flnb Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Sort1 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gga1 Vps18 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Gga1 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1AR, Protein Ap1ar Gga1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gga2 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Mon2 Gga1 ortho P Arf5 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Csnk2a1 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Cltc Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gga1 Clint1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdkn2a Gga1 ortho Protein Lrp3 Gga1 ortho Gga1 Rabepk ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gga1 Ccdc91 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Dhx15 Gga1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8R0H9 Q03517 biochemical 16601685 colocalization X 2 Q8R0H9 fluorescent resonance energy transfer 17005855 direct interaction X 2 Q8R0H9 cosedimentation 16615898 colocalization C 1216 Q8R0H9 Q6PJW8 confocal microscopy 19864490 colocalization X 2 Q8CBC4-3 Q8R0H9 pull down 19864490 direct interaction X 2 Q8CBC4-3 Q8R0H9 two hybrid 19864490 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8R0H9 P62259 GGA1 YWHAE 0.081 16615898 Q8R0H9 Q6PJW8 GGA1 CNST 0.126 19864490 Q8R0H9 P12023 GGA1 APP 0.309 17005855 Q8R0H9 Q8CBC4 GGA1 CNST 0.523 19864490 Q8R0H9 Q03517 GGA1 SCG2 0.126 16601685