PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Fasn Rfwd2 23269672 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trib1 Rfwd2 20410507 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G Ptpn11 Rfwd2 23269672 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Reg1 Rfwd2 23269672 biogrid exp, ortho G G G G G G Trib2 Rfwd2 20410507 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trib3 Rfwd2 20410507 biogrid exp, ortho G G G G G G G G G G G Crtc2 Rfwd2 17805301 dip exp, ortho G G G G G G G Sipa1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G Rfwd2 Foxo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Etv4 Rfwd2 ortho Stk40 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhab Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jund Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2d2 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct6a Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jun Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fosl2 Rfwd2 ortho G G G G G G G G G G G G G G Mdm4 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cul3 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cops7a Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dcaf11 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Junb Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct4 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa2 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Dda1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ets1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cul2 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cops6 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Zfp397, Zinc finger protein 397 Rfwd2 ortho G G G G G G G G G G G G G G Cct8 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cul4b Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Etv5 Rfwd2 ortho G G G G G G G G G G G G Protein Lrr1 Rfwd2 ortho G G G G G Wdr5 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Etv1 Rfwd2 ortho Ddb2 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dmc1 Rfwd2 ortho G Mdm2 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rb1cc1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct2 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atf6 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rfwd2 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cops8 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rfwd2 Skp1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Parp4 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G Protein Btbd2 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ercc8 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct5 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vprbp Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhaz Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cops7b Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cul4a Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Klhl42 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2d1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mvp Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Cops4 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rfwd2 Cul1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tcp1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fos Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Det1 Rfwd2 ortho Rchy1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cops5 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Grwd1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa8 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct7 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Elavl1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cops3 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tp53 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptpn1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct3 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ets2 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sfn Rfwd2 ortho G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P43137 Q9R1A8 affinity chromatography technology 23269672 physical association X 2 Q8K4K4 Q9R1A8 affinity chromatography technology 20410507 physical association X 2 Q8K4K3 Q9R1A8 affinity chromatography technology 20410507 physical association X 2 P35235 Q9R1A8 affinity chromatography technology 23269672 physical association X 2 P0CG48 Q9R1A8 affinity chromatography technology 12466024 physical association X 2 Q8K4K2 Q9R1A8 affinity chromatography technology 20410507 physical association X 2 G4WTR2 Q9R1A8 affinity chromatography technology 23833191 physical association X 2 P19096 Q9R1A8 affinity chromatography technology 23269672 physical association X 2 Q9R1A8 Q3U182 anti tag coimmunoprecipitation 17805301 physical association X 2 Q9R1A8 Q3U182 anti bait coimmunoprecipitation 17805301 physical association X 2 Q9R1A8 Q3U182 anti tag coimmunoprecipitation 17805301 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9R1A8 Q8K4K2 RFWD2 TRIB3 0.21 20410507 Q9R1A8 Q8K4K3 RFWD2 TRIB2 0.21 20410507 Q9R1A8 Q8K4K4 RFWD2 TRIB1 0.21 20410507 Q9R1A8 Q96524 RFWD2 CRY2 0.21 23833191 Q9R1A8 P35235 RFWD2 PTPN11 0.21 23269672 Q9R1A8 P0CG48 RFWD2 UBC 0.21 12466024 Q9R1A8 P43137 RFWD2 REG1 0.21 23269672 Q9R1A8 P19096 RFWD2 FASN 0.21 23269672