PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Nfkbib Arih2 23179078 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2e3 Arih2 19256485 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2l3 Arih2 11722579,10431818 biogrid exp, ortho P Ube2e1 Arih2 11722579 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2n Arih2 ortho P Ogt Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps3 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kpna6 Arih2 ortho P G G G G G G G G G G G G G Wdr91 Arih2 ortho P Cul5 Arih2 ortho P Ube2d1 Arih2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Socs6 Arih2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sgce Arih2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2e2 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Pabpn1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pdlim1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hk2 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Scamp2 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2l6 Arih2 ortho G G G G G G G G G Arap1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Cep126 Arih2 ortho Zfp41 Arih2 ortho Ehd1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ccdc33 Arih2 ortho Ube2t Arih2 ortho P G G G G G G G G G G G G Tceb1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2d2 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2r2 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Apex1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim27 Arih2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gfi1 Arih2 ortho G G G G G G Ppp2r1a Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rheb Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vcp Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup93 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eml4 Arih2 ortho P Ube2d2b Arih2 ortho P G Ube2v1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Papss2 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Eef1g Arih2 ortho P Parp6 Arih2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mpdu1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Arih2 Kcnq2 ortho G G G G G G G Il4r Arih2 ortho G G G G G G G G G G G G G G G G G G G Ralgps1 Arih2 ortho Ensa Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nmt1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rel Arih2 ortho G G G G Ntrk1 Arih2 ortho Nubp1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptn Arih2 ortho G G G G G G G G G G G G G G G G G G G G G G Vps53 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Slc1a6 Arih2 ortho G G G G Ube2d3 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kat5 Arih2 ortho Tp53 Arih2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Utp14a Arih2 ortho P Bub1 Arih2 ortho G G G G G G G G G G G G Disc1 Arih2 ortho Phf7 Arih2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Arih2 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cbr3 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G Ugp2 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pml Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G Mdm2 Arih2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dlst Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Notch1 Arih2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Twf2 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nedd8 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Asb9 Arih2 ortho G G Rpl8 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eef1a1 Arih2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crebl2 Arih2 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P68037 Q9Z1K6 - 10431818 - X 2 Q9Z1K6 O14933-2 two hybrid 11722579 direct interaction X 2 Q9Z1K6 P52482 two hybrid 11722579 direct interaction X 2 P52483 Q9Z1K6 two hybrid 19256485 direct interaction X 2 P68037 Q9Z1K6 two hybrid 11722579 direct interaction X 2 P68037 Q9Z1K6 affinity chromatography technology 11722579 physical association X 2 P68037 Q9Z1K6 affinity chromatography technology 10431818 physical association X 2 P68037 Q9Z1K6 two hybrid 10431818 direct interaction X 2 Q60778 Q9Z1K6 anti bait coimmunoprecipitation 23179078 physical association X 2 Q60778 Q9Z1K6 anti bait coimmunoprecipitation 23179078 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9Z1K6 O14933 ARIH2 UBE2L6 0.309 11722579 Q9Z1K6 P68037 ARIH2 UBE2L3 0.702 10431818,11722579 Q9Z1K6 P52482 ARIH2 UBE2E1 0.309 11722579 Q9Z1K6 P52483 ARIH2 UBE2E3 0.309 19256485