PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Sirt2 Zbtb3 20211142 biogrid exp G G Ubp1 Zbtb3 20211142 biogrid exp G G Mllt10 Zbtb3 20211142 biogrid exp G G Otx2 Zbtb3 20211142 biogrid exp Zbtb3 Polr3e 20211142 biogrid exp G G Gtf2a1l Zbtb3 ortho G Zbtb3 Zmym2 ortho Prox1 Zbtb3 ortho Bin1 Zbtb3 ortho G Irf6 Zbtb3 ortho Supt5h Zbtb3 ortho G G Pknox1 Zbtb3 ortho G G Gata4 Zbtb3 ortho G Thra Zbtb3 ortho G G Foxm1 Zbtb3 ortho G Eif5b Zbtb3 ortho G G Zbtb3 Bag3 ortho G G Elavl1 Zbtb3 ortho G G Zbtb3 Ankrd2 ortho Ikbkg Zbtb3 ortho G Nr3c1 Zbtb3 ortho G Pparg Zbtb3 ortho Jade2 Zbtb3 ortho Skil Zbtb3 ortho G G Lef1 Zbtb3 ortho G G Smad3 Zbtb3 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q91X45 two hybrid 20211142 direct interaction X 2 Q91X45 two hybrid 20211142 direct interaction X 2 Q91X45 two hybrid 20211142 direct interaction X 2 Q91X45 Q8VDQ8-3 two hybrid 20211142 direct interaction X 2 Q91X45 two hybrid 20211142 direct interaction X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Ubp1 Zbtb3 MI:0018(two hybrid) 20211142 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_313635 bait prey Zbtb3 Sirt2 MI:0018(two hybrid) 20211142 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_313731 prey bait Zbtb3 Otx2 MI:0018(two hybrid) 20211142 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_313470 prey bait Mllt10 Zbtb3 MI:0018(two hybrid) 20211142 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_313361 bait prey Zbtb3 Polr3e MI:0018(two hybrid) 20211142 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_313660 prey bait

PPI - HINT Gene A Gene B PMID Method Quality MLLT10 ZBTB3 20211142 0018 HT OTX2 ZBTB3 20211142 0018 HT UBP1 ZBTB3 20211142 0018 HT SIRT2 ZBTB3 20211142 0018 HT ZBTB3 POLR3E 20211142 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q91X45 O54826 ZBTB3 MLLT10 0.183 20211142 Q91X45 Q8VDQ8 ZBTB3 SIRT2 0.183 20211142 Q91X45 Q811S7 ZBTB3 UBP1 0.183 20211142 Q9CZT4 Q91X45 POLR3E ZBTB3 0.183 20211142