PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ncf4 Gbp6 protein, Guanylate binding protein 7, MCG141961, isoform CRA_a, Protein Gbp7 21551061 innatedb exp G G G G G G G G G G G G G G Ncf4 Hdac4 15102471 intact exp Ncf2 Ncf4 19903815,21551061 innatedb exp, ortho G G G G G G G G G G G G G G Ncf4 Ncf1 8679714 dip exp, ortho G G G G G G G G Txn Ncf4 ortho G G G G G G G G G G G G G G Xrcc6 Ncf4 ortho G G G G G G G G G G G G G G Ncf4 Cyba ortho G G G G G G G G G G G G G G Coro1a Ncf4 ortho G G G G G G G G G G G G G Msn Ncf4 ortho G G G G G G G G G G G G G G Prkdc Ncf4 ortho G G G G G G G G G G G G G G Ncf4 Mlh1 ortho G G G G G G G G G G G G G G Ncf4 Cybb ortho G G G G G G G G G G G G Prkcd Ncf4 ortho G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P97369 two hybrid 9490029 physical association X 2 P97369 Q09014 two hybrid 8679714 physical association X 2 P97369 Q6NZM9 two hybrid 15102471 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Ncf4 Ncf1 MI:0018(two hybrid) 8679714 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) MI:0465(dip) DIP_174 - - Ncf4 Hdac4 MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_164739 prey bait

PPI - HINT Gene A Gene B PMID Method Quality NCF2 NCF4 19903815 0107 LC NCF4 NCF1 8679714 0018 LC NCF4 HDAC4 15102471 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P97369 P19878 NCF4 NCF2 0.033 9490029 Q6NZM9 P97369 HDAC4 NCF4 0.183 15102471 Q09014 P97369 NCF1 NCF4 0.033 8679714