PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus spi Suppressor of cytokine signaling at 36E, isoform D 15710747 biogrid,i2d,mint,intact exp G G G G G G G G G G Suppressor of cytokine signaling at 36E, isoform D dmt 14605208 biogrid,i2d,mint,intact exp G G G G G G G Suppressor of cytokine signaling at 36E, isoform D AP-3 complex subunit beta 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G Src64B Suppressor of cytokine signaling at 36E, isoform D 14605208 biogrid,i2d,mint,intact exp G G G G G G G CG18135-PD, isoform D Suppressor of cytokine signaling at 36E, isoform D 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G Suppressor of cytokine signaling at 36E, isoform D GMF 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VJL6 Q8INY1 two hybrid 14605208 direct interaction X 2 A4V0W1 Q8INY1 two hybrid 15710747 direct interaction X 2 Q8INY1 Q9VVV6 two hybrid 14605208 direct interaction X 2 Q9W4K1 Q8INY1 two hybrid 14605208 direct interaction X 2 M9MSK3 Q8INY1 two hybrid 14605208 direct interaction X 2 Q9VH89 Q8INY1 two hybrid 14605208 direct interaction X 2 Q86BI9 Q8INY1 two hybrid 14605208 physical association X 2 Q9VJL6 Q8INY1 two hybrid 14605208 physical association X 2 A4V0W1 Q8INY1 two hybrid 15710747 physical association X 2 Q9W4K1 Q8INY1 two hybrid 14605208 physical association X 2 M9MSK3 Q8INY1 two hybrid 14605208 physical association X 2 Q9VH89 Q8INY1 two hybrid 14605208 physical association X 2 A4V0W1 Q8INY1 two hybrid fragment pooling approach 15710747 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8INY1 P00528 SOCS36E SRC64B 0.033 14605208 Q8INY1 Q01083 SOCS36E SPI 0.155 15710747