PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C BcDNA.GH02678 22036573 biogrid exp G G G G G G G G G G Neu3 LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 25294943 intact exp Syb LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 22036573 biogrid exp G G G G G G G G G G vps2 LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 22036573 biogrid exp G G G G G G G G G G Flo-2 LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 22036573 biogrid exp G G G G G G G G G CG9130-RA LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 14605208 i2d,mint,intact exp LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C Charged multivesicular body protein 2b, LD36173p 22036573 biogrid exp G G G G G G G G G G LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C cmb 22036573 biogrid exp G G G G SIP1-RA LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 22036573 biogrid exp Spinophilin, isoform J LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 25294943 intact exp G G G G G G NetB LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 25294943 intact exp G G G G G Charged multivesicular body protein 1, isoform A, Charged multivesicular body protein 1, isoform B, GH26351p LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 22036573 biogrid exp G G G G G G G G G G LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C dos 22036573 biogrid exp G G G G G G G G G G Dl LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 15710747 biogrid,i2d,intact exp G G G RE42507p, Stumps, isoform C LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C 12767830 i2d,intact exp G G G G G G G G G LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C chico 22068330,22036573 biogrid,intact exp G G G G G G G G G G LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C Charged multivesicular body protein 5 22036573 biogrid exp G G G G G G G G G G LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C CG7668-RA 22036573 biogrid exp G G G G G G G G G G LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C CG10103, isoform A, LD14015p 22036573 biogrid exp, ortho G G G G G G G G G G LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C mib1 ortho G G G G G G G G G G LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C ortho G G G G G G G G G G ik2-RB LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C ortho G G CG5603-PD, isoform D, Cylindromatosis ortholog, isoform E, FI01020p LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C ortho G G G G G G G G G G Set LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C ortho G G G G G G G G G G LD11955p, Mind bomb 2, isoform A, Mind bomb 2, isoform B, Mind bomb 2, isoform C AT16033p, CG3473, isoform A, CG3473, isoform B ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants A4V346 Q9VJ14 - 15710747 - X 2 Q9VJ14 - 14605208 - X 2 Q9VJ14 Q9VFH9 - 12767830 - X 2 Q9VJ14 Q8MLQ0 affinity chromatography technology 22036573 physical association X 2 Q9VJ14 M9PFI2 affinity chromatography technology 22036573 physical association X 2 Q9VJ14 Q95SH2 affinity chromatography technology 22036573 physical association X 2 Q9VJ14 Q9VBI3 affinity chromatography technology 22036573 physical association X 2 Q9VJ14 affinity chromatography technology 22036573 physical association X 2 Q9VW70 Q9VJ14 affinity chromatography technology 22036573 physical association X 2 A4V346 Q9VJ14 two hybrid 15710747 direct interaction X 2 Q9VJ14 Q9VVI9 affinity chromatography technology 22036573 physical association X 2 Q9VJ14 M9PCQ8 affinity chromatography technology 22036573 physical association X 2 Q9VJ14 M9PHL7 affinity chromatography technology 22036573 physical association X 2 Q9VJ14 Q9Y162 affinity chromatography technology 22036573 physical association X 2 Q9VJ14 H1UUB1 affinity chromatography technology 22036573 physical association X 2 Q9VRY6 Q9VJ14 affinity chromatography technology 22036573 physical association X 2 Q9VZZ9-2 Q9VJ14 affinity chromatography technology 22036573 physical association X 2 Q9VJ14 Q8IRH9 two hybrid 14605208 physical association X 2 A4V346 Q9VJ14 two hybrid 15710747 physical association X 2 Q9VJ14 Q8IRH9 two hybrid 14605208 physical association X 2 A4V346 Q9VJ14 two hybrid fragment pooling approach 15710747 physical association X 2 Q9VJ14 anti tag coimmunoprecipitation 22068330 association C 6 Q9VJ14 O96757 two hybrid 12767830 physical association X 2 Q9VJ14 O96757 two hybrid 12767830 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Flo-2 mib2 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_68735 bait prey Dl mib2 MI:0399(two hybrid fragment pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|MI:0465(dip) UniProt_42821|BIOGRID_61987|DIP_27857 bait|bait|- prey|prey|- vps2 mib2 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_73856 bait prey mib2 dos MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_65962 prey bait mib2 CG6259 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_65314 prey bait mib2 CG7668-RA MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_65085 prey bait HSPC300 mib2 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_66519 bait prey CG9130 mib2 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_55832|MINT_10106 bait|bait prey|prey mib2 CG10103 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_64884 prey bait Chmp1 mib2 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_72708 bait prey mib2 Vps4 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_71818 prey bait mib2 chico MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 22036573,22068330 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_68158|UniProt_46537 prey|prey bait|bait CG10732 mib2 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_70859 bait prey stumps mib2 MI:0018(two hybrid)|MI:0018(two hybrid) 12767830 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_38849|UniProt_38802 bait|bait prey|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9XTN2 Q9VJ14 CHICO MIB2 0.126 22068330 Q9VJ14 Q6QU65 MIB2 MELTRIN {ECO:0000313|FLYBASE:FBGN0265140} 0.126 25294943 Q9VJ14 O96757 MIB2 STUMPS 0.309 12767830 Q9VJ14 P10041 MIB2 DL 0.155 15710747 Q9VJ14 Q8IRH9 MIB2 CG9130-RA 0.183 14605208 Q9VJ14 M9NFI9 MIB2 M9NFI9 0.126 25294943 Q9VJ14 Q24568 MIB2 NETB 0.126 25294943