PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus F45C12.7 ZK20.3 11778048,14704431 biogrid,i2d,mint,intact exp R06B9.3 ZK20.3 14704431 biogrid,i2d,mint,intact,dip exp G ZK1240.2 ZK20.3 i2d exp C50F4.11, MDF-1 ZK20.3 11778048,14704431 biogrid,intact exp G ZK20.3 F35F10.12 i2d exp Uncharacterized F-box/LRR-repeat protein C02F5.7 ZK20.3 11778048 mint,intact exp G ZK20.3 Y77E11A.4 11778048,14704431 biogrid,i2d,mint,intact exp G ZK20.3 Y66H1A.6c 11778048 intact exp ZK20.3 F56F11.4b i2d exp C01G5.6 ZK20.3 11778048,14704431 biogrid,i2d,mint,intact exp G ZK20.3 cJTB-like i2d exp ZK20.3 C17E4.2 11778048,14704431 biogrid,i2d,mint,intact exp rfs-1 ZK20.3 i2d exp ZK20.3 Y76B12C.2 i2d exp B0205.3 ZK20.3 11778048,14704431 biogrid,i2d,mint,intact exp, ortho G K07G5.2 ZK20.3 i2d exp, ortho G ZK20.3 Proteasome subunit beta type i2d exp, ortho G rpt-1 ZK20.3 i2d exp, ortho G pbs-4 ZK20.3 i2d exp, ortho G rpn-12 ZK20.3 ortho G F36D4.3b, Hum-2 ZK20.3 ortho G ufd-2 ZK20.3 ortho ZC518.2 ZK20.3 ortho G rpt-4 ZK20.3 ortho G rpn-6.1 ZK20.3 ortho G ZK20.3 Y71H2B.3 ortho G T05C3.5 ZK20.3 ortho G rps-21 ZK20.3 ortho G ZK20.3 gspd-1 ortho G ZK20.3 Y66D12A.9 ortho G ZK20.3 png-1 ortho G R12E2.3 ZK20.3 ortho G F10G7.8 ZK20.3 ortho G cor-1 ZK20.3 ortho ZK20.3 DNA helicase ortho G ZK20.3 pas-2 ortho G uba-3 ZK20.3 ortho G aldo-1 ZK20.3 ortho G dph-1 ZK20.3 ortho G M01A10.3 ZK20.3 ortho G Y92H12A.2a ZK20.3 ortho G F57B10.9 ZK20.3 ortho G atx-3 ZK20.3 ortho ZK20.3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 ortho G T25G3.3 ZK20.3 ortho G ZK20.3 mdt-20 ortho atp-2 ZK20.3 ortho G glt-1 ZK20.3 ortho G ama-1 ZK20.3 ortho cyn-10 ZK20.3 ortho G ZK20.3 pas-3 ortho G tag-277 ZK20.3 ortho G ZK20.3 usp-7 ortho G ZK20.3 Y54G2A.31 ortho G T06D8.8 ZK20.3 ortho G gta-1 ZK20.3 ortho G unc-18 ZK20.3 ortho G wdr-5.1 ZK20.3 ortho G rnf-5 ZK20.3 ortho G ubq-1 ZK20.3 ortho G F55A12.9a ZK20.3 ortho G ZK20.3 Y43C5A.6a ortho Uncharacterized protein C30C11.4 ZK20.3 ortho G C31C9.2 ZK20.3 ortho G hda-6 ZK20.3 ortho G vdac-1 ZK20.3 ortho G ufd-1 ZK20.3 ortho G tbb-4 ZK20.3 ortho G W07E11.1a ZK20.3 ortho G rpn-3 ZK20.3 ortho G ZK20.3 C47E12.5a ortho G F32H2.5 ZK20.3 ortho G RNA-binding protein 8A ZK20.3 ortho G ubh-4 ZK20.3 ortho G pbs-6 ZK20.3 ortho G arx-2 ZK20.3 ortho G F15C11.2a ZK20.3 ortho G Protein disulfide-isomerase ZK20.3 ortho G rpt-3 ZK20.3 ortho G ZK20.3 ZK20.3 ortho G rpn-7 ZK20.3 ortho G rpt-2 ZK20.3 ortho G cyn-1 ZK20.3 ortho G Elongation factor Tu homologue, Y71H2AM.23 ZK20.3 ortho G F56H1.4 ZK20.3 ortho G C44E4.1a ZK20.3 ortho ZK20.3 Y79H2A.6 ortho G pas-7 ZK20.3 ortho G hsp-1 ZK20.3 ortho G ZK20.3 arx-1 ortho G acbp-1 ZK20.3 ortho G hrdl-1 ZK20.3 ortho G ZK20.3 Y66D12A.15 ortho G pas-1 ZK20.3 ortho G cdk-7 ZK20.3 ortho G F09E5.15b ZK20.3 ortho G dnc-2 ZK20.3 ortho G rpn-11 ZK20.3 ortho G M03C11.7 ZK20.3 ortho G ZK20.3 Y69A2AR.18b ortho G F22D6.2 ZK20.3 ortho G ZK20.3 K08E3.7a ortho G ZK20.3 Y47G6A.20b ortho G 1G758 ZK20.3 ortho G ZK20.3 C01G10.8 ortho G F38E9.5 ZK20.3 ortho G ZK20.3 T22D1.9 ortho G R02D3.3a ZK20.3 ortho G ZK20.3 ATP synthase subunit alpha, mitochondrial ortho G ZK20.3 spt-16 ortho G eef-2 ZK20.3 ortho G eef-1B.1 ZK20.3 ortho G C14C10.5a ZK20.3 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants G5EFM0 Q23451 two hybrid 14704431 direct interaction X 2 Q23451 Q93228 two hybrid 14704431 direct interaction X 2 O17982 Q23451 two hybrid 14704431 direct interaction X 2 Q23451 O16741 two hybrid 14704431 direct interaction X 2 Q23451 two hybrid 14704431 direct interaction X 2 Q17569 Q23451 two hybrid 14704431 direct interaction X 2 O61742 Q23451 two hybrid 14704431 direct interaction X 2 Q23451 two hybrid 14704431 direct interaction X 2 O17982 Q23451 two hybrid 14704431 physical association X 2 G5EFM0 Q23451 two hybrid pooling approach 11778048 physical association X 2 H2L0I7 Q23451 two hybrid pooling approach 11778048 physical association X 2 P34284 Q23451 two hybrid pooling approach 11778048 physical association X 2 Q23451 Q93228 two hybrid pooling approach 11778048 physical association X 2 O17982 Q23451 two hybrid pooling approach 14704431 physical association X 2 Q23451 O16741 two hybrid pooling approach 11778048 physical association X 2 Q17569 Q23451 two hybrid pooling approach 11778048 physical association X 2 Q9N4B5 Q23451 two hybrid pooling approach 11778048 physical association X 2 O61742 Q23451 two hybrid pooling approach 11778048 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B rad-23 Q9TYJ9 MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_3449 bait prey rad-23 C17E4.2 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|(intact) 113973|MINT_3446|UniProt_1453 bait|bait|bait prey|prey|prey arrd-13 rad-23 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0465(dip) UniProt_27434|MINT_1496|DIP_3048 bait|bait|- prey|prey|- rad-23 jtr-1 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|MI:0471(mint) 113985|UniProt_1457|MINT_3450 bait|bait|bait prey|prey|prey C01G5.6 rad-23 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|(intact) MINT_3445|113970|UniProt_1452 prey|prey|prey bait|bait|bait rad-23 hum-8 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_1456|113982 bait|bait prey|prey rpn-10 rad-23 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|MI:0471(mint) UniProt_1451|113967|MINT_3444 prey|prey|prey bait|bait|bait C02F5.7 rad-23 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|MI:0471(mint) UniProt_1465|114009|MINT_3635 bait|bait|bait prey|prey|prey rad-23 Q9NGT4 MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_3447 bait prey btb-6 rad-23 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|(intact) MINT_3448|113979|UniProt_1455 prey|prey|prey bait|bait|bait rad-23 mdf-1 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) 113976|UniProt_1454 bait|bait prey|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9N4B5 Q23451 JTR-1 RAD-23 0.126 11778048 Q23451 O61742 RAD-23 RPN-10 0.126 11778048 Q93228 Q23451 Q93228 RAD-23 0.126 11778048 Q23451 G5EFM0 RAD-23 MDF-1 0.126 11778048 Q23451 H2L0I7 RAD-23 HUM-8 0.126 11778048 Q23451 O16741 RAD-23 BTB-6 0.126 11778048 Q23451 P34284 RAD-23 P34284 0.126 11778048 Q23451 O17982 RAD-23 ARRD-13 0.155 14704431 Q23451 Q17569 RAD-23 Q17569 0.126 11778048