PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RPP1B PEX2 11283351 i2d,mint,intact,dip exp PEX2 EMP70 16093310 biogrid,dip exp SRO9 PEX2 22271760 biogrid exp ERG6 PEX2 21748599 biogrid exp PEX2 PEX18 24034674 biogrid exp PEX2 PET10 21748599 biogrid exp UBC4 PEX2 19687296,22471590,24034674 biogrid exp PEX2 SLF1 22271760 biogrid exp PEX2 GIS2 21232131 biogrid exp PEX2 MEC3 11283351 i2d,mint,intact,dip exp PEX2 PEX15 19687296, 23023127 biogrid exp, pred PEX2 PEX10 19687296,22471590,12667447,22500805, 23023127 biogrid,intact exp, pred PEX2 PEX11 22500805, 23023127 intact exp, pred PEX2 PEX5 19687296,12667447, 23023127 biogrid,intact exp, pred PEX2 PEX14 19687296,12667447,22500805,22375831, 23023127 biogrid,intact exp, pred PEX2 PEX13 19687296,12667447,22500805, 23023127 biogrid,intact exp, pred CRM1 PEX2 11283351, 23023127 i2d,mint,intact,dip exp, pred PEX2 PEX12 19687296,22471590,12667447,22500805, 23023127 biogrid,intact exp, pred PEX2 PEX17 12667447, 23023127 biogrid,intact exp, pred PEX2 PEX19 12876220, 23023127 biogrid,dip exp, pred PEX2 PEX8 12667447, 23023127 biogrid,intact exp, pred PEX2 PEX7 23023127 i2d exp, pred PEX4 PEX2 19687296,22471590, 23023127 biogrid exp, pred PEX2 PEX6 23023127 pred PEX3 PEX2 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P32800 Q02574 - 11283351 - X 2 P30822 P32800 - 11283351 - X 2 P10622 P32800 - 11283351 - X 2 P32800 P53112 protein complementation assay 22500805 direct interaction X 2 P32800 P53112 affinity chromatography technology 12667447 physical association X 2 P32800 P53112 affinity chromatography technology 12667447 physical association X 2 P32800 P40155 affinity chromatography technology 12667447 physical association X 2 P32800 Q07418 protein complementation assay 12876220 direct interaction X 2 P32800 P32802 protein complementation assay 16093310 direct interaction X 2 P32800 P53112 affinity chromatography technology 19687296 physical association X 2 P32800 Q08215 affinity chromatography technology 19687296 physical association X 2 P32800 P53112 affinity chromatography technology 22375831 physical association X 2 P53248 P32800 affinity chromatography technology 12667447 physical association X 2 P53248 P32800 affinity chromatography technology 12667447 physical association X 2 P29340 P32800 pull down 22471590 direct interaction X 2 P29340 P32800 affinity chromatography technology 19687296 physical association X 2 P25087 P32800 protein complementation assay 21748599 direct interaction X 2 Q04370 P32800 imaging technique 22500805 colocalization X 2 Q04370 P32800 affinity chromatography technology 12667447 physical association X 2 Q04370 P32800 affinity chromatography technology 12667447 physical association X 2 Q04370 P32800 pull down 22471590 direct interaction X 2 Q04370 P32800 pull down 22471590 direct interaction X 2 Q04370 P32800 affinity chromatography technology 19687296 physical association X 2 P32800 Q05568 protein complementation assay 22500805 direct interaction X 2 P32800 P80667 affinity chromatography technology 22500805 physical association X 2 P32800 Q05568 affinity chromatography technology 12667447 physical association X 2 P32800 P80667 affinity chromatography technology 12667447 physical association X 2 P32800 P35056 affinity chromatography technology 12667447 physical association X 2 P32800 Q05568 affinity chromatography technology 12667447 physical association X 2 P32800 P80667 affinity chromatography technology 12667447 physical association X 2 P32800 P35056 affinity chromatography technology 12667447 physical association X 2 P32800 P15731 pull down 22471590 direct interaction X 2 P32800 Q05568 pull down 22471590 direct interaction X 2 P32800 Q05568 pull down 22471590 direct interaction X 2 P32800 P38855 enzymatic study 24034674 direct interaction X 2 P32800 P15731 pull down 24034674 direct interaction X 2 P32800 P15731 affinity chromatography technology 19687296 physical association X 2 P32800 P35056 affinity chromatography technology 19687296 physical association X 2 P32800 P80667 affinity chromatography technology 19687296 physical association X 2 P32800 Q05568 affinity chromatography technology 19687296 physical association X 2 P32800 P36139 protein complementation assay 21748599 direct interaction X 2 P32800 P32802 ubiquitin reconstruction 16093310 physical association X 2 P32800 Q02574 two hybrid pooling approach 11283351 physical association X 2 P32800 Q07418 ubiquitin reconstruction 12876220 physical association X 2 P30822 P32800 two hybrid pooling approach 11283351 physical association X 2 P10622 P32800 two hybrid pooling approach 11283351 physical association X 2 P32800 pull down 12667447 association C 6 P32800 pull down 12667447 association C 6 P32800 pull down 12667447 association C 8 P32800 pull down 12667447 association C 8 P32800 pull down 12667447 association C 8 P32800 pull down 12667447 association C 8 P32800 pull down 12667447 association C 8 P32800 pull down 12667447 association C 4 P32800 Q02574 two hybrid fragment pooling approach 11283351 physical association X 2 P32800 Q12462 fluorescence microscopy 22500805 colocalization X 2 P32800 P53112 bimolecular fluorescence complementation 22500805 physical association X 2 P32800 P53112 bimolecular fluorescence complementation 22500805 physical association X 2 P30822 P32800 two hybrid fragment pooling approach 11283351 physical association X 2 P32800 pull down 12667447 association C 3 P32800 pull down 12667447 association C 3 P32800 pull down 12667447 association C 7 P32800 pull down 12667447 association C 7 Q04370 P32800 fluorescence microscopy 22500805 colocalization X 2 P32800 Q05568 bimolecular fluorescence complementation 22500805 physical association X 2 P32800 Q05568 bimolecular fluorescence complementation 22500805 physical association X 2 P32800 Q05568 fluorescence microscopy 22500805 colocalization X 2 P32800 Q05568 bimolecular fluorescence complementation 22500805 physical association X 2 P32800 P80667 anti tag coimmunoprecipitation 22500805 physical association X 2 P32800 P80667 fluorescence microscopy 22500805 colocalization X 2 P10622 P32800 two hybrid fragment pooling approach 11283351 physical association X 2 P32800 Q02574 two hybrid 11283351 - X 2 P32800 P39108 two hybrid - - X 2 P30822 P32800 two hybrid 11283351 - X 2 P10622 P32800 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality RPP1B PEX2 11283351,11283351,11283351 0018,0399,0398 HT ERG6 PEX2 21748599 0090 HT CRM1 PEX2 11283351,11283351,11283351 0018,0399,0398 HT PEX2 EMP70 16093310,16093310 0090,0112 HT PEX2 PET10 21748599 0090 HT PEX2 PEX18 24034674 0415 LC PEX2 PEX14 22500805,22500805,26644516 0090,0809,0090 LC PEX2 PEX13 22500805,22500805,22500805 0416,0004,0007 LC PEX2 MEC3 11283351,11283351,11283351 0018,0399,0398 HT PEX2 PEX12 22500805,22500805 0428,0416 LC PEX2 PEX10 22500805,22500805,22500805 0090,0809,0416 LC PEX2 PEX19 12876220,12876220 0112,0090 LC PEX2 PEX11 22500805 0416 LC UBC4 PEX2 19687296,24034674,22471590 0004,0096,0096 LC PEX4 PEX2 22471590,19687296 0096,0004 LC PEX2 PEX5 12667447,12667447,19687296 0096,0004,0004 LC PEX2 PEX17 12667447,12667447 0096,0004 LC PEX2 PEX14 19687296,12667447,12667447,22375831 0004,0004,0096,0004 LC PEX2 PEX8 12667447,12667447 0096,0004 LC PEX2 PEX13 22500805,12667447,12667447,22500805,22500805,19687296 0416,0004,0096,0004,0007,0004 LC PEX2 PEX12 22500805,19687296,12667447,22471590,12667447,22500805 0428,0004,0004,0096,0096,0416 LC PEX2 PEX10 19687296,12667447,22471590,12667447 0004,0004,0096,0096 LC PEX2 PEX15 19687296 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P32800 P25087 PEX2 ERG6 0.183 21748599 Q12462 P32800 PEX11 PEX2 0.126 22500805 P32800 P25567 PEX2 SRO9 0.126 22271760 Q05568 P32800 PEX10 PEX2 0.888 12667447,19687296,22471590,22500805 P35056 P32800 PEX5 PEX2 0.376 12667447,19687296 P32800 P29340 PEX2 PEX4 0.454 19687296,22471590 P80667 P32800 PEX13 PEX2 0.659 12667447,19687296,22500805 P32800 P15731 PEX2 UBC4 0.623 19687296,24034674,22471590 P53112 P32800 PEX14 PEX2 0.853 12667447,19687296,22375831,26644516,22500805 P32800 P10622 PEX2 RPP1B 0.236 11283351 P32800 P30822 PEX2 CRM1 0.21 11283351 P38855 P32800 PEX18 PEX2 0.309 24034674 P40155 P32800 PEX17 PEX2 0.21 12667447 P53248 P32800 PEX8 PEX2 0.376 12667447 Q02574 P32800 MEC3 PEX2 0.236 11283351 Q07418 P32800 PEX19 PEX2 0.21 12876220 Q08215 P32800 PEX15 PEX2 0.21 19687296 P32802 P32800 EMP70 PEX2 0.183 16093310 P36139 P32800 PET10 PEX2 0.183 21748599 P53849 P32800 GIS2 PEX2 0.126 21232131 Q04370 P32800 PEX12 PEX2 0.772 12667447,19687296,22471590,22500805