PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SSB1 Uncharacterized protein YJR141W 19536198 intact exp MCK1 Uncharacterized protein YJR141W 16319894 biogrid,i2d exp CDC28 Uncharacterized protein YJR141W 16319894 biogrid exp Uncharacterized protein YJR141W UBC7 14690591 intact exp SSE1 Uncharacterized protein YJR141W 19536198 intact exp HSL1 Uncharacterized protein YJR141W 16319894 biogrid,i2d exp Uncharacterized protein YJR141W NAF1 14690591 intact exp DDI1 Uncharacterized protein YJR141W 11283351 biogrid,i2d,mint,intact,dip exp MPE1 Uncharacterized protein YJR141W 14690591 i2d,intact exp Uncharacterized protein YJR141W BCK1 16319894 biogrid,i2d exp Uncharacterized protein YJR141W FRK1 16319894 biogrid,i2d exp SSA1 Uncharacterized protein YJR141W 19536198 intact exp RCK1 Uncharacterized protein YJR141W 16319894 biogrid,i2d exp VMA6 Uncharacterized protein YJR141W 11283351, 23023127 biogrid,i2d,mint,intact,dip exp, pred RFA3 Uncharacterized protein YJR141W 11805837, 23023127 biogrid,mint,intact,dip exp, pred Uncharacterized protein YJR141W ATP14 11283351, 23023127 i2d,mint,intact,dip exp, pred Uncharacterized protein YJR141W HSH49 14690591, 23023127 i2d,intact exp, pred Uncharacterized protein YJR141W NUP116 11283351, 23023127 i2d,mint,intact,dip exp, pred SIF2 Uncharacterized protein YJR141W 11283351, 23023127 biogrid,i2d,mint,intact,dip exp, pred Uncharacterized protein YJR141W RRP12 21482668, 23023127 biogrid exp, pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P47172 - 11805837 - C 11 P40087 P47172 - 11283351 - X 2 Q12349 P47172 - 11283351 - X 2 P47172 P38262 - 11283351 - X 2 Q02630 P47172 - 11283351 - X 2 P32366 P47172 - 11283351 - X 2 P35728 P47172 - 14690591 - X 2 Q99181 P47172 - 14690591 - X 2 P00546 P47172 enzymatic study 16319894 direct interaction X 2 Q03002 P47172 enzymatic study 16319894 direct interaction X 2 P40087 P47172 two hybrid 11283351 direct interaction X 2 P40087 P47172 two hybrid 11283351 direct interaction X 2 Q12754 P47172 affinity chromatography technology 21482668 physical association X 2 P47172 P21965 enzymatic study 16319894 direct interaction X 2 P47172 P38262 two hybrid 11283351 direct interaction X 2 P47172 P38262 two hybrid 11283351 direct interaction X 2 P34244 P47172 enzymatic study 16319894 direct interaction X 2 P26755 P47172 affinity chromatography technology 11805837 physical association X 2 P32366 P47172 two hybrid 11283351 direct interaction X 2 Q01389 P47172 enzymatic study 16319894 direct interaction X 2 P38622 P47172 enzymatic study 16319894 direct interaction X 2 P47172 anti tag coimmunoprecipitation 11805837 - C 11 P47172 anti tag coimmunoprecipitation 11805837 - C 30 P40087 P47172 two hybrid pooling approach 11283351 physical association X 2 P40087 P47172 two hybrid pooling approach 11283351 physical association X 2 Q12349 P47172 two hybrid pooling approach 11283351 physical association X 2 P47172 P38262 two hybrid pooling approach 11283351 physical association X 2 P47172 P38262 two hybrid pooling approach 11283351 physical association X 2 Q02630 P47172 two hybrid pooling approach 11283351 physical association X 2 P26755 P47172 anti tag coimmunoprecipitation 11805837 physical association X 2 P32366 P47172 two hybrid pooling approach 11283351 physical association X 2 P32589 P47172 tandem affinity purification 19536198 association X 2 P40087 P47172 two hybrid fragment pooling approach 11283351 physical association X 2 P40087 P47172 two hybrid fragment pooling approach 11283351 physical association X 2 Q12349 P47172 two hybrid fragment pooling approach 11283351 physical association X 2 P47172 anti tag coimmunoprecipitation 11805837 association C 11 P47172 P38262 two hybrid fragment pooling approach 11283351 physical association X 2 P47172 P38262 two hybrid fragment pooling approach 11283351 physical association X 2 P11484 P47172 tandem affinity purification 19536198 association X 2 Q02630 P47172 two hybrid fragment pooling approach 11283351 physical association X 2 Q02159 P47172 two hybrid array 14690591 physical association X 2 P32366 P47172 two hybrid fragment pooling approach 11283351 physical association X 2 P53919 P47172 two hybrid array 14690591 physical association X 2 P35728 P47172 two hybrid array 14690591 physical association X 2 Q99181 P47172 two hybrid array 14690591 physical association X 2 P10591 P47172 tandem affinity purification 19536198 association X 2 P47172 mass spectrometry studies of complexes 11805837 - C 12 P40087 P47172 two hybrid 11283351 - X 2 P40087 P47172 two hybrid 11283351 - X 2 Q12349 P47172 two hybrid 11283351 - X 2 P47172 P38262 two hybrid 11283351 - X 2 P47172 P38262 two hybrid 11283351 - X 2 Q02630 P47172 two hybrid 11283351 - X 2 P32366 P47172 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality CDC28 P47172 16319894 0415 LC MCK1 P47172 16319894 0415 LC VMA6 P47172 11283351,11283351,11283351 0018,0399,0398 HT HSL1 P47172 16319894 0415 LC MPE1 P47172 14690591,14690591 0018,0397 LC SIF2 P47172 11283351,11283351,11283351 0018,0399,0398 HT RCK1 P47172 16319894 0415 LC DDI1 P47172 11283351,11283351,11283351 0018,0399,0398 HT P47172 NAF1 14690591 0397 LC P47172 BCK1 16319894 0415 LC P47172 UBC7 14690591 0397 LC P47172 NUP116 11283351,11283351,11283351 0018,0399,0398 HT P47172 FRK1 16319894 0415 LC P47172 ATP14 11283351,11283351,11283351 0018,0399,0398 HT P47172 HSH49 14690591,14690591 0018,0397 LC SSA1 P47172 19536198 0676 HT SSB1 P47172 19536198 0676 HT RFA3 P47172 11805837,11805837 0004,0007 HT SSE1 P47172 19536198 0676 HT P47172 RRP12 21482668 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P47172 P00546 P47172 CDC28 0.183 16319894 P47172 P10591 P47172 SSA1 0.126 19536198 P47172 P11484 P47172 SSB1 0.126 19536198 P47172 P32366 P47172 VMA6 0.354 11283351 P47172 P38622 P47172 RCK1 0.183 16319894 P47172 P26755 P47172 RFA3 0.236 11805837 P47172 P40087 P47172 DDI1 0.416 11283351 P47172 P34244 P47172 HSL1 0.183 16319894 P47172 P32589 P47172 SSE1 0.126 19536198 P47172 P35728 P47172 MPE1 0.126 14690591 P47172 P38262 P47172 SIF2 0.523 11283351 P53919 P47172 NAF1 P47172 0.126 14690591 Q02159 P47172 UBC7 P47172 0.126 14690591 Q02630 P47172 NUP116 P47172 0.236 11283351 Q12349 P47172 ATP14 P47172 0.236 11283351 Q99181 P47172 HSH49 P47172 0.126 14690591 Q12754 P47172 RRP12 P47172 0.21 21482668 Q01389 P47172 BCK1 P47172 0.183 16319894 Q03002 P47172 FRK1 P47172 0.183 16319894 P47172 P21965 P47172 MCK1 0.183 16319894