iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	Phospho.ELM	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.20e-12	46.5	688	741

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFv 59
           kv + y yea+ +deL++ +Gd ++viek++ d++W+ ++ + +g +G +P  + 
   Q: 688  KVYAAYGYEAAFEDELSFDAGDELTVIEKDKVDKNWWTCE-KNNGEKGQVPRTYL 741
           78899**********************************5.89********9885 PP

Organism

Caenorhabditis elegans

Functional Description
(View)

Inhibitor of cep-1, which prevents the activation of apoptosis.

Protein Sequence
(Fasta)

MVTTSSGGGI GYPANNGVTQ VSLIHSSDSV RTVSTAPIYR PTSSMASTMA HKSSTAPFIS 60
ANQRMSKPPV RVVAQPPPPH PQALSQQYHQ QNPMMMYSAP NTRPHVIPTM QVQPTMAAQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATCTCAGT TCTCAACGAG ATGGTCACGA CCAGTAGCGG AGGGGGTATA GGGTACCCGG 60
CAAACAACGG TGTCACACAG GTGAGAATCG AGATTAATTA TTTTTCAAAT TGTTACAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0053--Apoptosis
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0656--Proto-oncogene
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001452--SH3_domain

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50002--SH3

Pfam

PF12796--Ank_2
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00248--ANK
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0002039--F:p53 binding
GO:0006915--P:apoptotic process
GO:0043066--P:negative regulation of apoptotic process

KEGG

cel:CELE_F46F3.4

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001642	Ailuropoda melanoleuca	52.05	1.00e-59	224.00
IUUC-Apl-004077	Anas platyrhynchos	51.14	2.00e-58	220.00
IUUC-Aca-005300	Anolis carolinensis	51.22	7.00e-55	208.00
IUUC-Ame-011289	Astyanax mexicanus	49.77	1.00e-56	213.00
IUUC-Bta-012477	Bos taurus	52.51	3.00e-60	226.00
IUUC-Cja-019672	Callithrix jacchus	51.60	1.00e-58	220.00
IUUC-Cfa-020703	Canis familiaris	51.60	1.00e-59	223.00
IUUC-Cpo-022364	Cavia porcellus	50.68	4.00e-58	218.00
IUUC-Csa-023051	Chlorocebus sabaeus	51.60	6.00e-59	221.00
IUUC-Cho-025060	Choloepus hoffmanni	50.73	3.00e-52	199.00
IUUC-Csv-025927	Ciona savignyi	52.05	2.00e-59	223.00
IUUC-Dre-028426	Danio rerio	51.14	4.00e-58	218.00
IUUC-Dno-029432	Dasypus novemcinctus	49.02	3.00e-48	186.00
IUUC-Dor-030603	Dipodomys ordii	49.53	2.00e-53	203.00
IUUC-Ete-032395	Echinops telfairi	49.77	1.00e-52	200.00
IUUC-Eca-033910	Equus caballus	51.60	5.00e-59	221.00
IUUC-Eeu-035287	Erinaceus europaeus	51.14	2.00e-58	219.00
IUUC-Fca-035913	Felis catus	51.60	1.00e-59	223.00
IUUC-Fal-036698	Ficedula albicollis	51.14	2.00e-58	219.00
IUUC-Gga-041256	Gallus gallus	51.14	2.00e-58	219.00
IUUC-Gac-041539	Gasterosteus aculeatus	49.77	2.00e-57	216.00
IUUC-Ggo-045619	Gorilla gorilla	51.60	2.00e-58	219.00
IUUC-Hsa-046506	Homo sapiens	51.14	2.00e-58	219.00
IUUC-Itr-048178	Ictidomys tridecemlineatus	51.14	3.00e-59	222.00
IUUC-Lch-050122	Latimeria chalumnae	43.04	1.00e-58	220.00
IUUC-Loc-052603	Lepisosteus oculatus	51.22	8.00e-54	204.00
IUUC-Laf-053834	Loxodonta africana	51.60	7.00e-59	221.00
IUUC-Mcc-055785	Macaca mulatta	51.60	7.00e-59	221.00
IUUC-Meu-056089	Macropus eugenii	51.14	3.00e-58	219.00
IUUC-Mga-059590	Meleagris gallopavo	51.14	1.00e-58	220.00
IUUC-Mmr-060975	Microcebus murinus	51.60	8.00e-59	221.00
IUUC-Mdo-063015	Monodelphis domestica	50.47	8.00e-57	214.00
IUUC-Mmu-064285	Mus musculus	51.14	1.00e-58	220.00
IUUC-Mpu-066414	Mustela putorius furo	52.97	3.00e-60	226.00
IUUC-Mlu-068059	Myotis lucifugus	51.14	4.00e-58	219.00
IUUC-Nle-069765	Nomascus leucogenys	50.47	1.00e-56	213.00
IUUC-Opr-070603	Ochotona princeps	51.14	2.00e-58	219.00
IUUC-Ont-072681	Oreochromis niloticus	49.77	5.00e-57	215.00
IUUC-Oan-073404	Ornithorhynchus anatinus	50.73	9.00e-55	207.00
IUUC-Ocu-074964	Oryctolagus cuniculus	50.68	6.00e-58	218.00
IUUC-Ola-086986	Oryzias latipes	50.28	1.00e-51	197.00
IUUC-Oga-088492	Otolemur garnettii	51.14	1.00e-58	220.00
IUUC-Oar-090212	Ovis aries	49.30	8.00e-54	204.00
IUUC-Ptr-091354	Pan troglodytes	51.60	7.00e-59	221.00
IUUC-Pan-092354	Papio anubis	51.60	7.00e-59	221.00
IUUC-Psi-093223	Pelodiscus sinensis	51.14	6.00e-59	221.00
IUUC-Pfo-097053	Poecilia formosa	48.68	2.00e-55	210.00
IUUC-Pab-097758	Pongo abelii	51.60	3.00e-59	222.00
IUUC-Pca-100736	Procavia capensis	51.60	1.00e-58	220.00
IUUC-Pva-102307	Pteropus vampyrus	50.68	6.00e-59	221.00
IUUC-Rno-105716	Rattus norvegicus	51.14	3.00e-58	219.00
IUUC-Sha-107553	Sarcophilus harrisii	51.14	5.00e-58	218.00
IUUC-Sar-113225	Sorex araneus	49.30	2.00e-54	206.00
IUUC-Ssc-115833	Sus scrofa	51.60	3.00e-59	222.00
IUUC-Tgu-116995	Taeniopygia guttata	51.14	2.00e-58	219.00
IUUC-Tru-118643	Takifugu rubripes	52.91	4.00e-57	215.00
IUUC-Tsy-119114	Tarsius syrichta	49.30	1.00e-51	197.00
IUUC-Tni-120786	Tetraodon nigroviridis	51.35	3.00e-55	209.00
IUUC-Tbe-127866	Tupaia belangeri	50.68	4.00e-58	219.00
IUUC-Ttr-128278	Tursiops truncatus	50.24	4.00e-52	199.00
IUUC-Vpa-130152	Vicugna pacos	50.24	1.00e-53	203.00
IUUC-Xtr-132886	Xenopus tropicalis	50.23	6.00e-57	214.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence