iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027927

Ensembl Protein ID

ENSDARP00000012720.5

UniProt Accession

Q567F1; Q567F1_DANRE

Genbank Protein ID

AAH93196.1; AAI65551.1

Protein Name

GRB2-related adaptor protein 2a; Zgc:112091; Zgc:112091 protein

Genbank Nucleotide ID

BX649558; BC165551

Gene Name

grap2a; zgc:112091

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000006468.8	ENSDART00000020381.6	ENSDARP00000012720.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.40e-32	110.5	231	284

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v+++yd++a++ddeL +++Gd+++v+  +  d+ W+kg   l+g++GlfP+n++e++
   Q: 231  QVRAIYDFTAEEDDELGFNSGDIIEVL--DRSDASWWKG--RLRGRSGLFPANYTEQI 284
           799************************..99********..9*************986 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MEARGKYDFS GTAEDELSFR KGDTLKILGS QDDWFKAELH GHEGYVPKNY VDRQIPSWFK 60
ESASRGSAEE TLMSREVGAF LIRGSQSSPG DFSISVRHDY DVQHFKVMKD KSGHYYLWTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATACACGGG CACGCGCATG CAGGTAGCGG TAGAAGAATT GAGGGTGAGA CACCAAGGAG 60
GTGGCAGTTT ATCTGCTGGA GGTTTCTTAT CTTTGTTGCT AAACAGCGAC ACAGCGGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR017304--NCK
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

dre:550452

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001994	Ailuropoda melanoleuca	49.04	5.00e-76	277.00
IUUC-Apl-003684	Anas platyrhynchos	47.40	2.00e-75	275.00
IUUC-Aca-005371	Anolis carolinensis	51.40	1.00e-75	276.00
IUUC-Ago-007771	Ashbya gossypii	35.94	4.00e-13	68.90
IUUC-Ame-011392	Astyanax mexicanus	73.04	1.00e-117	415.00
IUUC-Bta-013508	Bos taurus	45.89	2.00e-71	262.00
IUUC-Cfa-020290	Canis familiaris	49.04	1.00e-75	276.00
IUUC-Cpo-022534	Cavia porcellus	46.46	8.00e-71	260.00
IUUC-Csa-023438	Chlorocebus sabaeus	68.03	1.00e-57	217.00
IUUC-Cho-024466	Choloepus hoffmanni	50.34	1.00e-37	150.00
IUUC-Dno-029894	Dasypus novemcinctus	47.02	4.00e-73	268.00
IUUC-Dor-030493	Dipodomys ordii	69.39	7.00e-58	217.00
IUUC-Ete-032335	Echinops telfairi	57.05	5.00e-42	164.00
IUUC-Eca-033750	Equus caballus	48.41	1.00e-73	270.00
IUUC-Eeu-034884	Erinaceus europaeus	39.74	7.00e-44	171.00
IUUC-Fca-036001	Felis catus	48.56	4.00e-74	271.00
IUUC-Fal-036692	Ficedula albicollis	46.93	8.00e-78	283.00
IUUC-Gmo-039524	Gadus morhua	69.13	1.00e-59	223.00
IUUC-Gac-041301	Gasterosteus aculeatus	71.90	5.00e-63	234.00
IUUC-Ggo-045424	Gorilla gorilla	67.35	4.00e-57	215.00
IUUC-Hsa-045808	Homo sapiens	68.03	1.00e-57	217.00
IUUC-Itr-048000	Ictidomys tridecemlineatus	69.39	3.00e-58	218.00
IUUC-Lch-049610	Latimeria chalumnae	46.93	4.00e-67	248.00
IUUC-Loc-052925	Lepisosteus oculatus	61.46	8.00e-95	340.00
IUUC-Laf-054004	Loxodonta africana	47.69	1.00e-73	270.00
IUUC-Mcc-055020	Macaca mulatta	68.03	1.00e-57	217.00
IUUC-Mga-059483	Meleagris gallopavo	63.16	9.00e-56	210.00
IUUC-Mmr-061755	Microcebus murinus	47.98	6.00e-75	274.00
IUUC-Mdo-062504	Monodelphis domestica	45.37	2.00e-70	259.00
IUUC-Mmu-063557	Mus musculus	46.69	6.00e-73	267.00
IUUC-Mpu-066852	Mustela putorius furo	48.09	3.00e-75	275.00
IUUC-Mlu-067510	Myotis lucifugus	49.21	5.00e-75	274.00
IUUC-Nle-069691	Nomascus leucogenys	68.03	8.00e-58	217.00
IUUC-Opr-070271	Ochotona princeps	47.44	1.00e-72	266.00
IUUC-Ont-072651	Oreochromis niloticus	49.23	4.00e-80	291.00
IUUC-Oan-073183	Ornithorhynchus anatinus	48.61	4.00e-77	281.00
IUUC-Ocu-074899	Oryctolagus cuniculus	41.90	8.00e-60	223.00
IUUC-Ola-086462	Oryzias latipes	47.01	4.00e-79	288.00
IUUC-Oga-088553	Otolemur garnettii	46.50	3.00e-73	268.00
IUUC-Oar-089572	Ovis aries	44.94	2.00e-71	262.00
IUUC-Ptr-090582	Pan troglodytes	68.03	9.00e-58	217.00
IUUC-Pan-092063	Papio anubis	68.03	1.00e-57	217.00
IUUC-Psi-094056	Pelodiscus sinensis	47.71	4.00e-77	281.00
IUUC-Pfo-096115	Poecilia formosa	60.68	3.00e-98	351.00
IUUC-Pab-098217	Pongo abelii	68.03	9.00e-58	217.00
IUUC-Pca-100838	Procavia capensis	48.12	2.00e-71	262.00
IUUC-Pva-102559	Pteropus vampyrus	70.75	7.00e-60	224.00
IUUC-Rno-105926	Rattus norvegicus	37.69	2.00e-53	202.00
IUUC-Sha-106948	Sarcophilus harrisii	49.51	4.00e-74	271.00
IUUC-Ssc-115605	Sus scrofa	45.91	2.00e-72	265.00
IUUC-Tgu-117211	Taeniopygia guttata	47.53	4.00e-77	281.00
IUUC-Tru-118347	Takifugu rubripes	56.90	3.00e-72	264.00
IUUC-Tsy-119441	Tarsius syrichta	47.32	5.00e-73	268.00
IUUC-Tni-119732	Tetraodon nigroviridis	52.45	2.00e-92	332.00
IUUC-Tbe-127289	Tupaia belangeri	68.71	3.00e-58	218.00
IUUC-Ttr-128961	Tursiops truncatus	67.76	6.00e-59	221.00
IUUC-Xtr-131814	Xenopus tropicalis	64.63	5.00e-55	207.00
IUUC-Xma-133547	Xiphophorus maculatus	68.79	2.00e-62	233.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence