iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/GAT	3.10e-52	176.3	98	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/GAT

   S: 1    deeksklLerLlkskkPeDLreAnkLikelvkededkaekikkliseleevksnvkllnemlselspegeepednellqelyetckaar 89
           deeksk+L+rLlks++PeDLr+AnkLike+v+ed++++eki+k+++++eev++nvkll+em++++s++++++++++l++ely++c+++r
   Q: 98   DEEKSKMLARLLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGAASSSSEDLMKELYQRCERMR 186
           79*************************************************************************************** PP
   S: 90   pkllklieeeedndellaellkanDelnqvlnkykqlk 127
           p+l++l++++ednde+lae+l+anD+l+qv+n ykql+
   Q: 187  PTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLV 224
           ***********************************987 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MKSCGKRFHD EVGKFRFLNE LIKVVSPKYL GSRTSEKVKN KILELLYSWT VGLPEEVKIA 60
EAYQMLKKQG IVKSDPKLPE DAIFPLPPPR PKNVIFEDEE KSKMLARLLK SSHPEDLRAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGCTCAGA CTTGGGGGCT GTCCAACAAG TGGAGGGAAT CACCTCCCAC GCGCTCAATC 60
CCTCTTAACC GTGCCCGTTG CAGGATAGTT AGGGAGGCAG AAATTTCACT CTCCCATTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR008152--Clathrin_a/b/g-adaptin_app_Ig
IPR008153--Clathrin_g-adaptin_app
IPR013041--Coatomer/clathrin_app_Ig-like
IPR008942--ENTH_VHS
IPR004152--GAT_dom
IPR002014--VHS_dom

PROSITE

PS50180--GAE
PS50909--GAT
PS50179--VHS

Pfam

PF02883--Alpha_adaptinC2
PF03127--GAT
PF00790--VHS

SMART

SM00809--Alpha_adaptinC2

Gene Ontology

GO:0030131--C:clathrin adaptor complex
GO:0005654--C:nucleoplasm
GO:0006886--P:intracellular protein transport
GO:0045732--P:positive regulation of protein catabolic process
GO:1901998--P:toxin transport
GO:0016192--P:vesicle-mediated transport

KEGG

rno:300066

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001226	Ailuropoda melanoleuca	84.07	0.00e+00	842.00
IUUC-Apl-003932	Anas platyrhynchos	80.86	1.00e-135	476.00
IUUC-Afl-008682	Aspergillus flavus	24.57	3.00e-20	93.60
IUUC-Ame-011684	Astyanax mexicanus	70.00	1.00e-107	383.00
IUUC-Bta-012975	Bos taurus	89.03	0.00e+00	891.00
IUUC-Cja-019098	Callithrix jacchus	82.46	0.00e+00	792.00
IUUC-Cfa-020394	Canis familiaris	89.03	0.00e+00	874.00
IUUC-Cpo-022352	Cavia porcellus	89.56	0.00e+00	923.00
IUUC-Csa-024037	Chlorocebus sabaeus	90.46	0.00e+00	868.00
IUUC-Csv-026066	Ciona savignyi	39.68	1.00e-110	394.00
IUUC-Dre-027709	Danio rerio	62.81	1.00e-179	623.00
IUUC-Dno-029170	Dasypus novemcinctus	79.37	0.00e+00	752.00
IUUC-Dor-030638	Dipodomys ordii	89.38	0.00e+00	902.00
IUUC-Eca-034275	Equus caballus	88.65	0.00e+00	893.00
IUUC-Eeu-035068	Erinaceus europaeus	69.56	0.00e+00	697.00
IUUC-Fca-036278	Felis catus	95.85	4.00e-121	429.00
IUUC-Fal-036971	Ficedula albicollis	78.95	0.00e+00	782.00
IUUC-Gmo-039301	Gadus morhua	57.39	8.00e-119	421.00
IUUC-Gga-040880	Gallus gallus	75.00	0.00e+00	764.00
IUUC-Gac-041955	Gasterosteus aculeatus	60.87	1.00e-168	586.00
IUUC-Ggo-045652	Gorilla gorilla	90.28	0.00e+00	863.00
IUUC-Hsa-045919	Homo sapiens	90.28	0.00e+00	864.00
IUUC-Itr-048105	Ictidomys tridecemlineatus	90.41	0.00e+00	932.00
IUUC-Lch-049488	Latimeria chalumnae	66.67	0.00e+00	646.00
IUUC-Laf-053697	Loxodonta africana	86.02	0.00e+00	843.00
IUUC-Mcc-054687	Macaca mulatta	86.93	0.00e+00	793.00
IUUC-Meu-056352	Macropus eugenii	73.85	0.00e+00	705.00
IUUC-Mpo-057584	Magnaporthe poae	28.75	6.00e-09	55.80
IUUC-Mga-059936	Meleagris gallopavo	78.85	0.00e+00	789.00
IUUC-Mmr-060805	Microcebus murinus	86.22	0.00e+00	836.00
IUUC-Mdo-061808	Monodelphis domestica	79.05	0.00e+00	755.00
IUUC-Mmu-063131	Mus musculus	95.91	0.00e+00	895.00
IUUC-Mpu-066602	Mustela putorius furo	86.07	0.00e+00	881.00
IUUC-Mlu-068220	Myotis lucifugus	88.65	0.00e+00	849.00
IUUC-Nle-069039	Nomascus leucogenys	90.46	0.00e+00	861.00
IUUC-Opr-070709	Ochotona princeps	82.98	0.00e+00	851.00
IUUC-Ont-072069	Oreochromis niloticus	60.03	1.00e-172	600.00
IUUC-Oan-072906	Ornithorhynchus anatinus	70.69	0.00e+00	734.00
IUUC-Ola-086728	Oryzias latipes	54.35	1.00e-156	546.00
IUUC-Oga-088189	Otolemur garnettii	85.87	0.00e+00	836.00
IUUC-Oar-089226	Ovis aries	86.40	0.00e+00	849.00
IUUC-Pan-092529	Papio anubis	90.64	0.00e+00	870.00
IUUC-Psi-093412	Pelodiscus sinensis	72.05	0.00e+00	761.00
IUUC-Pfo-096458	Poecilia formosa	59.65	2.00e-173	602.00
IUUC-Pab-097684	Pongo abelii	89.22	0.00e+00	807.00
IUUC-Pca-100546	Procavia capensis	86.90	0.00e+00	653.00
IUUC-Pva-102877	Pteropus vampyrus	83.72	0.00e+00	839.00
IUUC-Sha-107248	Sarcophilus harrisii	78.11	0.00e+00	709.00
IUUC-Ssc-115539	Sus scrofa	81.40	2.00e-102	365.00
IUUC-Tgu-117227	Taeniopygia guttata	78.21	0.00e+00	781.00
IUUC-Tru-118666	Takifugu rubripes	57.14	6.00e-169	587.00
IUUC-Tni-120663	Tetraodon nigroviridis	59.49	5.00e-160	557.00
IUUC-Tbe-127589	Tupaia belangeri	89.03	0.00e+00	828.00
IUUC-Ttr-128616	Tursiops truncatus	89.56	0.00e+00	920.00
IUUC-Xtr-132596	Xenopus tropicalis	63.05	1.00e-123	436.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence