iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000020681.2	ENSCJAT00000040642.1	ENSCJAP00000038467.1
ENSCJAG00000020681.2	ENSCJAT00000040641.1	ENSCJAP00000038466.1
ENSCJAG00000020681.2	ENSCJAT00000040635.2	ENSCJAP00000038461.2
ENSCJAG00000020681.2	ENSCJAT00000040644.1	ENSCJAP00000038469.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.40e-08	34.2	29	70
E3 activity/RING/U-box	1.30e-07	32.6	27	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle +k+ p++  CgH f++ C+ +w        + f CP+Cr
   Q: 29   CSVCLEYLKE-PVIIECGHNFCKACITRW---WEDLERDFPCPVCR 70
           ********99.999************999...666889999****8 PP

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlpsGitydrssIekwlasggk..tcPvtrqplteedlvPnltlrrl 64
             C++ le  ++Pv++++G+ + +++I +w ++ ++   cPv+r++ + ++l Pn  l ++
   Q: 27   ASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERdfPCPVCRKTSRYRSLRPNRQLGSM 87
           68*****************************88887799****************998666 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAETSLLEAG ASAASTAAAL ENLQVEASCS VCLEYLKEPV IIECGHNFCK ACITRWWEDL 60
ERDFPCPVCR KTSRYRSLRP NRQLGSMVEI AKQLQAVKRK IRDESLCPQH HEALSLFCYE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGGGTTCC ACTGACACCA GCCTCGGTGC GGCTTCCGCT TCCGGCGAGT ATTGTGTGTC 60
GCGCCGCGGG GCGGGGGCGA GGGGAGGAGG AAGGAGGGAG GCAGCGCTCC GGCGGCTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0016874--F:ligase activity
GO:0008270--F:zinc ion binding
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2001235--P:positive regulation of apoptotic signaling pathway

KEGG

cjc:100401591

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001603	Ailuropoda melanoleuca	98.98	0.00e+00	962.00
IUUC-Apl-003354	Anas platyrhynchos	43.36	4.00e-109	388.00
IUUC-Aca-005381	Anolis carolinensis	70.97	0.00e+00	682.00
IUUC-Ame-011964	Astyanax mexicanus	33.62	1.00e-69	256.00
IUUC-Bta-012554	Bos taurus	97.87	2.00e-159	555.00
IUUC-Cfa-020342	Canis familiaris	99.14	0.00e+00	959.00
IUUC-Cpo-022084	Cavia porcellus	96.81	2.00e-157	548.00
IUUC-Csa-023186	Chlorocebus sabaeus	99.79	0.00e+00	966.00
IUUC-Cho-024697	Choloepus hoffmanni	86.84	0.00e+00	857.00
IUUC-Dre-028792	Danio rerio	35.68	2.00e-73	270.00
IUUC-Dor-031021	Dipodomys ordii	87.18	5.00e-145	507.00
IUUC-Ete-032936	Echinops telfairi	86.59	2.00e-153	534.00
IUUC-Eca-033687	Equus caballus	98.23	4.00e-160	557.00
IUUC-Eeu-034957	Erinaceus europaeus	99.55	5.00e-132	464.00
IUUC-Fca-035406	Felis catus	98.93	0.00e+00	959.00
IUUC-Fal-036705	Ficedula albicollis	46.49	7.00e-100	357.00
IUUC-Gmo-038505	Gadus morhua	35.21	3.00e-72	266.00
IUUC-Gac-041919	Gasterosteus aculeatus	36.19	1.00e-72	266.00
IUUC-Ggo-044526	Gorilla gorilla	93.76	0.00e+00	946.00
IUUC-Hsa-045719	Homo sapiens	93.76	0.00e+00	947.00
IUUC-Itr-048404	Ictidomys tridecemlineatus	97.47	0.00e+00	949.00
IUUC-Lch-049668	Latimeria chalumnae	40.00	8.00e-90	324.00
IUUC-Loc-052206	Lepisosteus oculatus	38.25	3.00e-86	312.00
IUUC-Laf-054295	Loxodonta africana	98.29	0.00e+00	956.00
IUUC-Mcc-055765	Macaca mulatta	95.10	0.00e+00	949.00
IUUC-Meu-055997	Macropus eugenii	61.60	2.00e-132	465.00
IUUC-Mga-059412	Meleagris gallopavo	43.35	2.00e-102	365.00
IUUC-Mmr-061030	Microcebus murinus	98.57	0.00e+00	678.00
IUUC-Mdo-062936	Monodelphis domestica	89.46	0.00e+00	854.00
IUUC-Mmu-063767	Mus musculus	97.43	0.00e+00	943.00
IUUC-Mpu-066160	Mustela putorius furo	98.98	0.00e+00	962.00
IUUC-Mlu-068126	Myotis lucifugus	95.39	3.00e-155	541.00
IUUC-Nle-070041	Nomascus leucogenys	89.37	0.00e+00	816.00
IUUC-Opr-070394	Ochotona princeps	93.52	0.00e+00	942.00
IUUC-Ont-071285	Oreochromis niloticus	34.90	7.00e-75	274.00
IUUC-Oan-072828	Ornithorhynchus anatinus	57.75	2.00e-162	565.00
IUUC-Ocu-073980	Oryctolagus cuniculus	97.57	0.00e+00	697.00
IUUC-Ola-086686	Oryzias latipes	32.26	7.00e-65	241.00
IUUC-Oga-088422	Otolemur garnettii	94.20	0.00e+00	905.00
IUUC-Oar-089277	Ovis aries	94.00	0.00e+00	885.00
IUUC-Ptr-090853	Pan troglodytes	93.76	0.00e+00	946.00
IUUC-Pan-091993	Papio anubis	99.79	0.00e+00	966.00
IUUC-Psi-092975	Pelodiscus sinensis	75.23	0.00e+00	650.00
IUUC-Pma-094519	Petromyzon marinus	27.11	8.00e-29	121.00
IUUC-Pfo-096831	Poecilia formosa	33.40	8.00e-70	257.00
IUUC-Pab-097944	Pongo abelii	99.79	0.00e+00	966.00
IUUC-Pca-100795	Procavia capensis	82.49	2.00e-167	582.00
IUUC-Pva-103180	Pteropus vampyrus	92.18	0.00e+00	928.00
IUUC-Rno-105736	Rattus norvegicus	95.58	0.00e+00	932.00
IUUC-Sha-107411	Sarcophilus harrisii	53.08	7.00e-148	516.00
IUUC-Sar-113371	Sorex araneus	89.81	0.00e+00	751.00
IUUC-Ssc-116025	Sus scrofa	99.57	0.00e+00	964.00
IUUC-Tgu-116998	Taeniopygia guttata	47.46	9.00e-103	367.00
IUUC-Tru-117532	Takifugu rubripes	33.54	5.00e-71	261.00
IUUC-Tsy-119072	Tarsius syrichta	86.34	2.00e-180	624.00
IUUC-Tbe-127820	Tupaia belangeri	87.94	4.00e-140	491.00
IUUC-Ttr-128310	Tursiops truncatus	99.10	1.00e-132	466.00
IUUC-Vpa-130803	Vicugna pacos	93.55	0.00e+00	946.00
IUUC-Xtr-132440	Xenopus tropicalis	36.05	2.00e-84	306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence