iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025577

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01002264

Gene Name

LOC100179266

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000007851.3	ENSCINT00000016064.3	ENSCINP00000016064.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.80e-43	149.4	145	335

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseike...llveeelykryekllleevveadaa 87
           C vCl +l  ++l+  l+C h+fC  C+kq++  ++k+g+ + i c+++ec+  ++++ +k+   +  ++ l + y+  l++ +v+++++
   Q: 145  CGVCLETLHRSKLL-ALNCGHQFCDGCWKQHMVFAVKDGMSQGIPCMEPECTLLCHPDFVKQfypVNQDSPLETAYKTHLFRISVSSHYQ 233
           99***888887766.67*********************************************444477888999**************** PP
   S: 88   lkwcpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegC 177
           l++cp  dC  v+  ek  +  +v+c +c+++fC+eC +  H +++C+++k++l+k++   +++e++++++an+k+CpkC+++iekn+gC
   Q: 234  LRFCPGVDCTSVIYGEKP-KPRKVQCLTCKTAFCFECGTPPHIPTNCETIKKWLTKCA---DDSETANYISANTKDCPKCHICIEKNGGC 319
           ************999997.999************************************...99*************************** PP
   S: 178  nhmtCakCkaefCwlC 193
           nh++C+kC ++fCw+C
   Q: 320  NHIKCSKCSHNFCWMC 335
           **************** PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

CSDDYEDDEE DINNYYNNNE DDFADSEEED GDSTSNNNDI KTSNNNDINQ SGIIMTSKLE 60
HFSSKTMTVS ETNEFLWKDC DKASVVLSIT PAMSRLVLQA SKWKLAVIKT RLYKTNKPNF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTCTGATG ATTATGAAGA TGACGAAGAA GACATCAATA ATTATTACAA CAACAACGAG 60
GATGATTTTG CCGACAGTGA GGAGGAAGAT GGAGACTCAA CTTCGAATAA TAACGACATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001557	Ailuropoda melanoleuca	53.52	1.00e-136	478.00
IUUC-Apl-003878	Anas platyrhynchos	54.63	3.00e-138	483.00
IUUC-Aca-004865	Anolis carolinensis	53.63	3.00e-137	480.00
IUUC-Bta-012901	Bos taurus	53.74	5.00e-137	479.00
IUUC-Cel-018334	Caenorhabditis elegans	48.92	9.00e-116	409.00
IUUC-Cja-019728	Callithrix jacchus	53.52	1.00e-136	478.00
IUUC-Cfa-020953	Canis familiaris	53.52	1.00e-136	478.00
IUUC-Cpo-021445	Cavia porcellus	53.30	4.00e-136	476.00
IUUC-Csa-023769	Chlorocebus sabaeus	53.08	9.00e-136	475.00
IUUC-Cho-024650	Choloepus hoffmanni	46.92	2.00e-109	387.00
IUUC-Csv-025849	Ciona savignyi	78.12	3.00e-179	619.00
IUUC-Dre-028490	Danio rerio	54.57	1.00e-136	478.00
IUUC-Dno-029942	Dasypus novemcinctus	53.74	7.00e-137	479.00
IUUC-Dor-030134	Dipodomys ordii	52.72	2.00e-91	327.00
IUUC-Dme-031853	Drosophila melanogaster	46.40	2.00e-116	410.00
IUUC-Ete-032355	Echinops telfairi	48.24	8.00e-117	412.00
IUUC-Eca-033440	Equus caballus	53.52	2.00e-136	478.00
IUUC-Eeu-035230	Erinaceus europaeus	63.95	2.00e-82	297.00
IUUC-Fca-036308	Felis catus	51.86	1.00e-129	455.00
IUUC-Fal-036974	Ficedula albicollis	54.63	3.00e-138	483.00
IUUC-Gmo-038642	Gadus morhua	58.79	3.00e-134	470.00
IUUC-Gga-041019	Gallus gallus	54.63	3.00e-138	483.00
IUUC-Gac-042014	Gasterosteus aculeatus	53.95	6.00e-139	486.00
IUUC-Ggo-045329	Gorilla gorilla	53.52	3.00e-136	477.00
IUUC-Hsa-046712	Homo sapiens	53.52	3.00e-136	477.00
IUUC-Itr-048370	Ictidomys tridecemlineatus	56.76	3.00e-135	473.00
IUUC-Lch-049584	Latimeria chalumnae	54.61	9.00e-138	481.00
IUUC-Loc-051826	Lepisosteus oculatus	52.96	9.00e-82	295.00
IUUC-Laf-054567	Loxodonta africana	51.67	9.00e-134	468.00
IUUC-Mcc-054919	Macaca mulatta	53.08	9.00e-136	475.00
IUUC-Meu-056332	Macropus eugenii	51.76	1.00e-131	461.00
IUUC-Mga-060132	Meleagris gallopavo	53.96	7.00e-140	489.00
IUUC-Mmr-061599	Microcebus murinus	50.88	3.00e-126	443.00
IUUC-Mdo-062186	Monodelphis domestica	57.18	6.00e-134	469.00
IUUC-Mmu-064271	Mus musculus	53.08	9.00e-136	475.00
IUUC-Mpu-066827	Mustela putorius furo	56.93	2.00e-134	471.00
IUUC-Mlu-067528	Myotis lucifugus	52.86	8.00e-133	465.00
IUUC-Nle-068995	Nomascus leucogenys	53.52	3.00e-136	477.00
IUUC-Opr-070518	Ochotona princeps	53.41	2.00e-135	474.00
IUUC-Ont-071650	Oreochromis niloticus	53.93	2.00e-138	484.00
IUUC-Oan-073676	Ornithorhynchus anatinus	56.90	8.00e-130	455.00
IUUC-Ocu-073761	Oryctolagus cuniculus	53.30	4.00e-136	476.00
IUUC-Ola-087204	Oryzias latipes	53.08	7.00e-134	469.00
IUUC-Olu-087826	Ostreococcus lucimarinus	30.47	2.00e-45	175.00
IUUC-Oga-088098	Otolemur garnettii	53.30	4.00e-136	476.00
IUUC-Oar-089205	Ovis aries	53.74	5.00e-137	479.00
IUUC-Ptr-091514	Pan troglodytes	53.52	3.00e-136	477.00
IUUC-Pan-092493	Papio anubis	50.00	1.00e-123	435.00
IUUC-Pfo-097256	Poecilia formosa	53.73	1.00e-138	484.00
IUUC-Pab-098504	Pongo abelii	47.80	6.00e-112	396.00
IUUC-Pca-100700	Procavia capensis	48.68	1.00e-114	405.00
IUUC-Pva-103105	Pteropus vampyrus	52.97	6.00e-133	466.00
IUUC-Rno-105289	Rattus norvegicus	53.08	6.00e-136	476.00
IUUC-Sha-107417	Sarcophilus harrisii	52.97	1.00e-132	465.00
IUUC-Ssl-108406	Sclerotinia sclerotiorum	25.00	8.00e-10	57.00
IUUC-Sar-113042	Sorex araneus	53.52	1.00e-136	478.00
IUUC-Ssc-115362	Sus scrofa	53.41	3.00e-136	476.00
IUUC-Tgu-117469	Taeniopygia guttata	54.15	8.00e-130	455.00
IUUC-Tru-117976	Takifugu rubripes	52.56	2.00e-138	484.00
IUUC-Tni-119831	Tetraodon nigroviridis	52.56	8.00e-137	479.00
IUUC-Tbe-127386	Tupaia belangeri	41.55	4.00e-62	230.00
IUUC-Ttr-128315	Tursiops truncatus	53.52	2.00e-136	477.00
IUUC-Vpa-130383	Vicugna pacos	48.90	5.00e-116	409.00
IUUC-Xtr-132945	Xenopus tropicalis	53.74	7.00e-136	475.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence