iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-28	99.1	251	301

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrsk 54
           + C +C+++++++ + v+Ce+C++ +H+ Cl +   +  p+   w C++Cr +
   Q: 251  TKCQICRQQDSNDTKYVKCEQCQKTYHASCLRPV-ISAIPKYG-WKCNRCRVC 301
           68*******************************9.88889887.******965 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSTNVVVSME EKAVADDLPY FPEKFPGKVC CLCNLGEKSA LGQGEILQLK APAPAEIKDK 60
YPTDRLREDG SRLLYGPKQA ASSSGDCHYE LDKIGQPDVV HPAEFLDEGF VYVHRMCIMW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAACATTGG GGCGCGATGC ACGTTGACAT TTTATTTAGC TGTCGAGTAA TGTATACAAA 60
ATAAGCGGCG GCTATTTTTT GTTATTTTAA TGAAACGCAT CAATCCGCGA TGAGCACGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR009071--HMG_box_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00249--PHD
SM00184--RING

Gene Ontology

GO:0008230--C:ecdysone receptor holocomplex
GO:0044666--C:MLL3/4 complex
GO:0005700--C:polytene chromosome
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0071390--P:cellular response to ecdysone
GO:0018990--P:ecdysis, chitin-based cuticle
GO:0035076--P:ecdysone receptor-mediated signaling pathway
GO:0051568--P:histone H3-K4 methylation
GO:0008586--P:imaginal disc-derived wing vein morphogenesis
GO:0007474--P:imaginal disc-derived wing vein specification
GO:0006909--P:phagocytosis
GO:1900114--P:positive regulation of histone H3-K9 trimethylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	34.12	2.00e-66	249.00
IUUC-Atr-003006	Amborella trichopoda	28.73	2.00e-23	103.00
IUUC-Apl-003311	Anas platyrhynchos	34.83	6.00e-67	251.00
IUUC-Aca-004705	Anolis carolinensis	33.62	7.00e-67	250.00
IUUC-Aly-006363	Arabidopsis lyrata	33.15	2.00e-23	103.00
IUUC-Ath-007307	Arabidopsis thaliana	31.11	1.00e-22	100.00
IUUC-Ame-010612	Astyanax mexicanus	32.57	2.00e-53	206.00
IUUC-Bta-012322	Bos taurus	33.60	1.00e-66	249.00
IUUC-Bdi-014882	Brachypodium distachyon	31.35	7.00e-23	101.00
IUUC-Bol-015791	Brassica oleracea	32.78	4.00e-24	105.00
IUUC-Bra-017422	Brassica rapa	32.78	6.00e-24	105.00
IUUC-Cel-018354	Caenorhabditis elegans	37.80	3.00e-38	154.00
IUUC-Cja-019983	Callithrix jacchus	33.60	8.00e-68	253.00
IUUC-Cfa-020903	Canis familiaris	33.60	2.00e-67	252.00
IUUC-Cpo-021732	Cavia porcellus	32.60	5.00e-68	254.00
IUUC-Csa-023083	Chlorocebus sabaeus	33.40	3.00e-68	255.00
IUUC-Cho-024469	Choloepus hoffmanni	41.03	5.00e-35	144.00
IUUC-Dre-028110	Danio rerio	35.36	8.00e-67	250.00
IUUC-Dno-029932	Dasypus novemcinctus	44.00	8.00e-54	207.00
IUUC-Dor-030569	Dipodomys ordii	34.15	1.00e-62	236.00
IUUC-Eca-033945	Equus caballus	33.40	2.00e-67	252.00
IUUC-Eeu-034848	Erinaceus europaeus	42.50	4.00e-51	198.00
IUUC-Fca-035922	Felis catus	33.40	4.00e-68	254.00
IUUC-Fal-037179	Ficedula albicollis	30.82	8.00e-50	194.00
IUUC-Gmo-039403	Gadus morhua	43.88	2.00e-57	219.00
IUUC-Gga-040815	Gallus gallus	34.19	7.00e-49	190.00
IUUC-Gac-042436	Gasterosteus aculeatus	31.58	3.00e-55	211.00
IUUC-Gma-043720	Glycine max	33.89	5.00e-26	112.00
IUUC-Ggo-044812	Gorilla gorilla	33.09	4.00e-61	231.00
IUUC-Hsa-046595	Homo sapiens	33.20	3.00e-68	255.00
IUUC-Hvu-047762	Hordeum vulgare	34.59	2.00e-17	83.60
IUUC-Itr-048303	Ictidomys tridecemlineatus	33.60	1.00e-67	253.00
IUUC-Lch-050086	Latimeria chalumnae	37.10	4.00e-61	231.00
IUUC-Lpe-051476	Leersia perrieri	30.20	2.00e-20	94.00
IUUC-Loc-052891	Lepisosteus oculatus	34.75	2.00e-63	239.00
IUUC-Laf-054348	Loxodonta africana	46.04	5.00e-59	223.00
IUUC-Mcc-054868	Macaca mulatta	33.40	2.00e-68	255.00
IUUC-Meu-055992	Macropus eugenii	41.05	9.00e-54	207.00
IUUC-Mtr-058482	Medicago truncatula	35.38	2.00e-19	90.50
IUUC-Mga-059541	Meleagris gallopavo	33.47	6.00e-67	251.00
IUUC-Mmr-061092	Microcebus murinus	33.14	3.00e-66	248.00
IUUC-Mdo-062610	Monodelphis domestica	34.15	5.00e-67	249.00
IUUC-Mmu-063666	Mus musculus	33.40	2.00e-67	252.00
IUUC-Mac-064935	Musa acuminata	33.15	9.00e-26	111.00
IUUC-Mpu-066366	Mustela putorius furo	32.99	3.00e-66	248.00
IUUC-Mlu-068201	Myotis lucifugus	33.81	5.00e-68	254.00
IUUC-Nle-069232	Nomascus leucogenys	33.25	2.00e-63	238.00
IUUC-Opr-070304	Ochotona princeps	44.00	7.00e-54	207.00
IUUC-Ont-071881	Oreochromis niloticus	32.71	2.00e-54	209.00
IUUC-Oan-072945	Ornithorhynchus anatinus	33.54	7.00e-66	247.00
IUUC-Ocu-074920	Oryctolagus cuniculus	34.17	3.00e-69	258.00
IUUC-Oba-075328	Oryza barthii	34.03	1.00e-18	87.80
IUUC-Obr-076458	Oryza brachyantha	33.16	4.00e-24	105.00
IUUC-Ogl-077851	Oryza glaberrima	32.62	1.00e-23	103.00
IUUC-Ogu-078706	Oryza glumaepatula	32.62	6.00e-24	105.00
IUUC-Oin-079802	Oryza indica	28.24	2.00e-19	89.70
IUUC-Olo-080932	Oryza longistaminata	32.62	6.00e-24	105.00
IUUC-Ome-081892	Oryza meridionalis	31.53	3.00e-13	69.30
IUUC-Oni-082043	Oryza nivara	32.62	5.00e-24	105.00
IUUC-Opu-083679	Oryza punctata	32.62	1.00e-23	103.00
IUUC-Oru-084257	Oryza rufipogon	32.62	8.00e-24	105.00
IUUC-Osa-085421	Oryza sativa	32.62	2.00e-23	103.00
IUUC-Ola-086436	Oryzias latipes	38.08	2.00e-58	222.00
IUUC-Oga-088637	Otolemur garnettii	34.01	3.00e-69	257.00
IUUC-Oar-089363	Ovis aries	33.40	5.00e-67	251.00
IUUC-Ptr-091527	Pan troglodytes	33.01	8.00e-68	253.00
IUUC-Pan-092102	Papio anubis	31.29	4.00e-66	248.00
IUUC-Pma-094252	Petromyzon marinus	30.79	1.00e-59	225.00
IUUC-Ppa-095221	Physcomitrella patens	34.25	9.00e-27	114.00
IUUC-Pab-098241	Pongo abelii	33.01	4.00e-66	248.00
IUUC-Pop-099585	Populus trichocarpa	33.33	3.00e-24	106.00
IUUC-Pca-100103	Procavia capensis	33.17	4.00e-64	241.00
IUUC-Ppe-101920	Prunus persica	31.67	2.00e-24	107.00
IUUC-Pva-102238	Pteropus vampyrus	34.25	8.00e-65	243.00
IUUC-Rno-105395	Rattus norvegicus	31.32	3.00e-61	229.00
IUUC-Sha-106550	Sarcophilus harrisii	34.35	2.00e-67	252.00
IUUC-Smo-109598	Selaginella moellendorffii	28.76	2.00e-22	100.00
IUUC-Sit-110552	Setaria italica	32.09	4.00e-23	102.00
IUUC-Sly-111442	Solanum lycopersicum	32.54	4.00e-26	112.00
IUUC-Sar-113183	Sorex araneus	42.47	7.00e-52	200.00
IUUC-Sbi-113816	Sorghum bicolor	33.94	2.00e-13	70.90
IUUC-Ssc-115678	Sus scrofa	44.00	3.00e-54	208.00
IUUC-Tgu-116677	Taeniopygia guttata	33.47	5.00e-67	251.00
IUUC-Tru-118037	Takifugu rubripes	39.72	1.00e-59	226.00
IUUC-Tsy-118932	Tarsius syrichta	43.36	4.00e-53	204.00
IUUC-Tni-120809	Tetraodon nigroviridis	31.84	5.00e-61	230.00
IUUC-Tca-121624	Theobroma cacao	32.02	4.00e-24	106.00
IUUC-Tae-124493	Triticum aestivum	34.59	8.00e-18	84.70
IUUC-Ttr-129051	Tursiops truncatus	33.81	7.00e-68	254.00
IUUC-Vpa-130236	Vicugna pacos	32.42	3.00e-58	221.00
IUUC-Vvi-131236	Vitis vinifera	31.71	7.00e-24	104.00
IUUC-Xtr-132455	Xenopus tropicalis	36.84	4.00e-59	224.00
IUUC-Xma-133751	Xiphophorus maculatus	33.77	6.00e-54	207.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence