iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Mmu-063254

Ensembl Protein ID

ENSMUSP00000033342.6

UniProt Accession

Q9DCH4; Q5XJV3; EIF3F_MOUSE

Genbank Protein ID

BAB22352.1; EDL16920.1; AAH83190.1

Protein Name

Eukaryotic translation initiation factor 3 subunit F; Deubiquitinating enzyme eIF3f; Eukaryotic translation initiation factor 3 subunit 5; eIF-3-epsilon; eIF3 p47

Genbank Nucleotide ID

AK002778; CH466531; BC083190

Gene Name

Eif3f; Eif3s5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000031029.6	ENSMUST00000033342.6	ENSMUSP00000033342.6

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	miRNAMap
RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
DUB/JAMM	99.25	2.00e-159	559.00	IUUC-Hsa-046860

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Functional Description
(View)

Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling.

Protein Sequence
(Fasta)

MASPAVPANV PPATAAAAPA PVVTAAPASA PTPSTPAPTP AATPAASPAP VSSDPAVAAP 60
AAPGQTPASA PAPAQTPAPS QPGPALPGPF PGGRVVRLHP VILASIVDSY ERRNEGAARV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTTTCTCG GCAAGATGGC TTCTCCGGCC GTACCGGCTA ATGTCCCTCC TGCCACTGCA 60
GCCGCAGCCC CGGCGCCGGT CGTCACCGCA GCCCCGGCTT CAGCCCCGAC CCCATCCACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0378--Hydrolase
KW-0396--Initiation factor
KW-0597--Phosphoprotein
KW-0645--Protease
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR027531--eIF3f
IPR000555--JAMM/MPN+_dom
IPR024969--Rpn11/EIF3F_C

Pfam

PF01398--JAB
PF13012--MitMem_reg

SMART

SM00232--JAB_MPN

Gene Ontology

GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0071541--C:eukaryotic translation initiation factor 3 complex, eIF3m
GO:0016020--C:membrane
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0003743--F:translation initiation factor activity
GO:0031369--F:translation initiation factor binding
GO:0075522--P:IRES-dependent viral translational initiation
GO:0016579--P:protein deubiquitination
GO:0006413--P:translational initiation

KEGG

mmu:66085

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001150	Aegilops tauschii	37.21	1.00e-47	183.00
IUUC-Aml-001527	Ailuropoda melanoleuca	99.25	1.00e-160	559.00
IUUC-Atr-002686	Amborella trichopoda	41.44	2.00e-50	192.00
IUUC-Apl-003977	Anas platyrhynchos	90.18	1.00e-120	425.00
IUUC-Aca-004335	Anolis carolinensis	90.00	6.00e-147	513.00
IUUC-Aly-005945	Arabidopsis lyrata	38.78	3.00e-50	191.00
IUUC-Ath-007045	Arabidopsis thaliana	39.16	3.00e-50	191.00
IUUC-Acl-008365	Aspergillus clavatus	34.80	4.00e-41	161.00
IUUC-Afl-008742	Aspergillus flavus	35.53	3.00e-40	159.00
IUUC-Afu-009030	Aspergillus fumigatus	34.43	8.00e-41	160.00
IUUC-Ani-009212	Aspergillus nidulans	35.29	1.00e-41	163.00
IUUC-Ang-009712	Aspergillus niger	34.31	9.00e-40	157.00
IUUC-Aor-009885	Aspergillus oryzae	35.53	8.00e-42	164.00
IUUC-Ate-010315	Aspergillus terreus	35.53	1.00e-39	156.00
IUUC-Ame-010801	Astyanax mexicanus	53.33	9.00e-67	246.00
IUUC-Bgr-011982	Blumeria graminis	35.17	3.00e-40	158.00
IUUC-Bta-012804	Bos taurus	98.57	2.00e-166	578.00
IUUC-Bci-013891	Botrytis cinerea	35.14	5.00e-35	141.00
IUUC-Bdi-014328	Brachypodium distachyon	40.00	4.00e-49	187.00
IUUC-Bol-015446	Brassica oleracea	39.16	4.00e-51	194.00
IUUC-Bra-016862	Brassica rapa	39.54	1.00e-51	196.00
IUUC-Cel-018171	Caenorhabditis elegans	35.54	2.00e-46	179.00
IUUC-Cja-019335	Callithrix jacchus	99.26	2.00e-163	568.00
IUUC-Cfa-020138	Canis familiaris	98.88	3.00e-160	557.00
IUUC-Cpo-022109	Cavia porcellus	86.91	2.00e-135	475.00
IUUC-Cre-022664	Chlamydomonas reinhardtii	38.43	7.00e-57	214.00
IUUC-Csa-023994	Chlorocebus sabaeus	99.26	2.00e-163	568.00
IUUC-Cho-024351	Choloepus hoffmanni	76.10	1.00e-113	402.00
IUUC-Cin-025801	Ciona intestinalis	56.51	5.00e-88	317.00
IUUC-Csv-025805	Ciona savignyi	55.39	2.00e-85	308.00
IUUC-Cgl-026643	Colletotrichum gloeosporioides	31.87	2.00e-35	142.00
IUUC-Cne-026868	Cryptococcus neoformans	29.15	4.00e-28	118.00
IUUC-Cme-027328	Cyanidioschyzon merolae	27.22	1.00e-22	100.00
IUUC-Dre-028085	Danio rerio	80.30	5.00e-129	453.00
IUUC-Dno-030099	Dasypus novemcinctus	98.88	4.00e-160	557.00
IUUC-Dor-030324	Dipodomys ordii	90.30	4.00e-139	487.00
IUUC-Dse-031314	Dothistroma septosporum	36.13	3.00e-44	172.00
IUUC-Dme-031926	Drosophila melanogaster	48.89	5.00e-76	277.00
IUUC-Ete-032569	Echinops telfairi	92.45	3.00e-151	527.00
IUUC-Eca-033502	Equus caballus	93.93	3.00e-153	534.00
IUUC-Eeu-034883	Erinaceus europaeus	81.08	2.00e-81	294.00
IUUC-Fca-035873	Felis catus	99.25	1.00e-160	559.00
IUUC-Fal-036921	Ficedula albicollis	91.48	5.00e-148	516.00
IUUC-Fox-037765	Fusarium oxysporum	32.61	8.00e-30	124.00
IUUC-Fso-038240	Fusarium solani	33.33	4.00e-32	132.00
IUUC-Gmo-038864	Gadus morhua	78.44	1.00e-128	452.00
IUUC-Ggr-039862	Gaeumannomyces graminis	31.52	8.00e-30	124.00
IUUC-Gga-040952	Gallus gallus	91.54	2.00e-149	521.00
IUUC-Gac-041677	Gasterosteus aculeatus	79.55	4.00e-129	453.00
IUUC-Gma-043061	Glycine max	41.06	1.00e-49	189.00
IUUC-Ggo-045591	Gorilla gorilla	99.26	7.00e-164	569.00
IUUC-Hsa-046860	Homo sapiens	99.26	2.00e-163	568.00
IUUC-Hvu-047410	Hordeum vulgare	31.08	3.00e-20	90.90
IUUC-Itr-048211	Ictidomys tridecemlineatus	98.88	3.00e-160	557.00
IUUC-Lch-049410	Latimeria chalumnae	73.79	2.00e-86	311.00
IUUC-Lpe-051102	Leersia perrieri	40.39	6.00e-48	184.00
IUUC-Loc-052016	Lepisosteus oculatus	69.72	2.00e-113	401.00
IUUC-Lma-053157	Leptosphaeria maculans	34.15	7.00e-43	167.00
IUUC-Laf-054568	Loxodonta africana	98.53	7.00e-163	566.00
IUUC-Mcc-054613	Macaca mulatta	99.26	1.00e-163	569.00
IUUC-Meu-056832	Macropus eugenii	72.86	2.00e-82	298.00
IUUC-Mor-057104	Magnaporthe oryzae	31.32	5.00e-30	125.00
IUUC-Mtr-058445	Medicago truncatula	41.06	8.00e-59	220.00
IUUC-Mla-059038	Melampsora laricipopulina	31.12	3.00e-32	132.00
IUUC-Mga-059548	Meleagris gallopavo	91.10	4.00e-128	450.00
IUUC-Mvi-060520	Microbotryum violaceum	27.95	3.00e-22	99.00
IUUC-Mdo-062376	Monodelphis domestica	93.66	4.00e-149	520.00
IUUC-Mac-065635	Musa acuminata	40.73	2.00e-51	195.00
IUUC-Mpu-066314	Mustela putorius furo	99.25	1.00e-160	558.00
IUUC-Mlu-067512	Myotis lucifugus	97.39	2.00e-155	541.00
IUUC-Nfi-068262	Neosartorya fischeri	34.43	9.00e-41	160.00
IUUC-Ncr-068872	Neurospora crassa	32.61	2.00e-32	133.00
IUUC-Nle-070118	Nomascus leucogenys	99.25	1.00e-160	559.00
IUUC-Opr-071228	Ochotona princeps	98.72	6.00e-140	489.00
IUUC-Ont-072600	Oreochromis niloticus	80.67	1.00e-131	462.00
IUUC-Oan-073584	Ornithorhynchus anatinus	92.80	1.00e-131	462.00
IUUC-Ocu-074542	Oryctolagus cuniculus	98.88	6.00e-160	556.00
IUUC-Oba-075923	Oryza barthii	39.35	4.00e-51	194.00
IUUC-Obr-076313	Oryza brachyantha	40.39	2.00e-49	188.00
IUUC-Ogl-076932	Oryza glaberrima	39.35	4.00e-51	194.00
IUUC-Ogu-078152	Oryza glumaepatula	39.35	4.00e-51	194.00
IUUC-Oin-079528	Oryza indica	39.35	4.00e-51	194.00
IUUC-Olo-080401	Oryza longistaminata	39.35	4.00e-51	194.00
IUUC-Ome-081553	Oryza meridionalis	38.99	9.00e-51	193.00
IUUC-Oni-082090	Oryza nivara	39.35	4.00e-51	194.00
IUUC-Opu-083583	Oryza punctata	40.39	7.00e-49	187.00
IUUC-Oru-084492	Oryza rufipogon	39.35	4.00e-51	194.00
IUUC-Osa-085383	Oryza sativa	39.35	4.00e-51	194.00
IUUC-Ola-086835	Oryzias latipes	79.55	1.00e-128	452.00
IUUC-Olu-087716	Ostreococcus lucimarinus	28.95	2.00e-28	119.00
IUUC-Oga-088886	Otolemur garnettii	98.51	1.00e-159	555.00
IUUC-Oar-090079	Ovis aries	98.57	5.00e-164	570.00
IUUC-Ptr-091457	Pan troglodytes	99.26	2.00e-163	568.00
IUUC-Pan-092317	Papio anubis	98.92	1.00e-107	382.00
IUUC-Psi-093129	Pelodiscus sinensis	84.94	9.00e-129	452.00
IUUC-Pma-094488	Petromyzon marinus	76.21	3.00e-123	434.00
IUUC-Pno-095049	Phaeosphaeria nodorum	34.15	5.00e-43	168.00
IUUC-Ppa-095341	Physcomitrella patens	41.57	4.00e-64	237.00
IUUC-Pfo-096286	Poecilia formosa	79.18	2.00e-129	454.00
IUUC-Pab-097765	Pongo abelii	99.26	2.00e-163	568.00
IUUC-Pop-099131	Populus trichocarpa	40.68	2.00e-54	205.00
IUUC-Pca-100524	Procavia capensis	82.05	4.00e-107	380.00
IUUC-Ppe-101934	Prunus persica	41.83	2.00e-59	222.00
IUUC-Pva-102577	Pteropus vampyrus	98.51	8.00e-160	556.00
IUUC-Pgr-103521	Puccinia graminis	30.19	2.00e-31	129.00
IUUC-Pte-104304	Pyrenophora teres	34.97	2.00e-43	169.00
IUUC-Pyt-104563	Pyrenophora triticirepentis	34.84	1.00e-43	170.00
IUUC-Rno-105717	Rattus norvegicus	99.63	2.00e-161	561.00
IUUC-Sha-107190	Sarcophilus harrisii	93.87	3.00e-145	507.00
IUUC-Sja-107918	Schizosaccharomyces japonicus	35.89	1.00e-45	176.00
IUUC-Spo-108355	Schizosaccharomyces pombe	35.84	1.00e-45	176.00
IUUC-Smo-109374	Selaginella moellendorffii	44.28	4.00e-68	251.00
IUUC-Sit-110119	Setaria italica	39.92	6.00e-50	190.00
IUUC-Sly-111570	Solanum lycopersicum	37.34	3.00e-46	178.00
IUUC-Stu-112308	Solanum tuberosum	39.66	3.00e-52	198.00
IUUC-Sar-113515	Sorex araneus	95.74	8.00e-51	192.00
IUUC-Sbi-114605	Sorghum bicolor	39.54	1.00e-49	190.00
IUUC-Sre-114906	Sporisorium reilianum	39.78	9.00e-52	196.00
IUUC-Tgu-117087	Taeniopygia guttata	89.41	1.00e-125	441.00
IUUC-Tru-117700	Takifugu rubripes	78.81	2.00e-128	451.00
IUUC-Tni-120470	Tetraodon nigroviridis	79.55	3.00e-129	454.00
IUUC-Tca-121109	Theobroma cacao	39.92	4.00e-48	184.00
IUUC-Tre-122095	Trichoderma reesei	33.94	3.00e-32	132.00
IUUC-Tvi-122580	Trichoderma virens	33.57	2.00e-31	130.00
IUUC-Tae-125129	Triticum aestivum	39.50	3.00e-52	198.00
IUUC-Tur-126658	Triticum urartu	36.11	2.00e-43	169.00
IUUC-Tme-127043	Tuber melanosporum	38.58	1.00e-47	183.00
IUUC-Tbe-127927	Tupaia belangeri	99.25	1.00e-160	559.00
IUUC-Ttr-129231	Tursiops truncatus	98.88	3.00e-160	557.00
IUUC-Uma-129578	Ustilago maydis	39.42	2.00e-50	192.00
IUUC-Vda-129730	Verticillium dahliae	32.25	5.00e-37	148.00
IUUC-Vpa-130677	Vicugna pacos	64.75	4.00e-42	165.00
IUUC-Vvi-130968	Vitis vinifera	41.06	1.00e-52	199.00
IUUC-Xtr-132203	Xenopus tropicalis	84.39	1.00e-135	475.00
IUUC-Xma-133972	Xiphophorus maculatus	78.81	5.00e-129	453.00
IUUC-Yli-134553	Yarrowia lipolytica	36.33	5.00e-40	157.00
IUUC-Zma-134941	Zea mays	39.16	2.00e-45	176.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence