iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116676

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01049187

Gene Name

SOCS5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000002631.1	ENSTGUT00000002731.1	ENSTGUP00000002703.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	8.30e-16	57.5	474	519

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
            l r+ p+SLq++CR +I+rc++++++   d LPLP++L+d+L++++y+
   Q: 474  SLNRTFPFSLQYICRAVICRCTTYDGI---DDLPLPSMLQDFLKEYHYK 519
           577899*********************...****************985 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MDKVGKMWNN FKYRCQNLFS HEGGSQNESI VVNSNNCSSG KEKAIQITDL TQQPSSPLRE 60
DIALQLGLSP SKNSARRNQN CVTEIPQIVE ISIEKENDSC VTTGARLARR DSYSRHAPWG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATAAAG TGGGAAAGAT GTGGAACAAT TTCAAATACA GATGCCAGAA TCTCTTTAGT 60
CATGAGGGTG GAAGCCAAAA TGAGAGTATA GTTGTGAACT CCAATAATTG CTCATCTGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0071404--P:cellular response to low-density lipoprotein particle stimulus
GO:0019221--P:cytokine-mediated signaling pathway
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0050728--P:negative regulation of inflammatory response
GO:0032715--P:negative regulation of interleukin-6 production
GO:0071638--P:negative regulation of monocyte chemotactic protein-1 production
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045627--P:positive regulation of T-helper 1 cell differentiation
GO:0016567--P:protein ubiquitination
GO:0097699--P:vascular endothelial cell response to fluid shear stress

KEGG

tgu:100222989

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003815	Anas platyrhynchos	96.64	0.00e+00	1060.00
IUUC-Aca-004504	Anolis carolinensis	86.57	0.00e+00	879.00
IUUC-Ath-007174	Arabidopsis thaliana	32.73	3.20e+00	26.20
IUUC-Ame-010677	Astyanax mexicanus	63.94	0.00e+00	642.00
IUUC-Bta-012338	Bos taurus	91.42	0.00e+00	981.00
IUUC-Cja-019828	Callithrix jacchus	91.79	0.00e+00	966.00
IUUC-Cfa-020369	Canis familiaris	91.23	0.00e+00	985.00
IUUC-Cpo-021397	Cavia porcellus	89.55	0.00e+00	987.00
IUUC-Csa-023856	Chlorocebus sabaeus	91.60	0.00e+00	983.00
IUUC-Dre-028262	Danio rerio	62.99	3.00e-170	591.00
IUUC-Dno-029019	Dasypus novemcinctus	91.60	0.00e+00	1006.00
IUUC-Dme-031965	Drosophila melanogaster	67.44	9.00e-70	258.00
IUUC-Eca-033867	Equus caballus	90.30	0.00e+00	994.00
IUUC-Fca-035806	Felis catus	91.23	0.00e+00	975.00
IUUC-Fal-037117	Ficedula albicollis	98.32	0.00e+00	1061.00
IUUC-Gmo-039066	Gadus morhua	83.49	2.00e-107	382.00
IUUC-Gga-040876	Gallus gallus	96.08	0.00e+00	1025.00
IUUC-Gac-042149	Gasterosteus aculeatus	65.81	0.00e+00	636.00
IUUC-Ggo-045169	Gorilla gorilla	90.86	0.00e+00	976.00
IUUC-Hsa-045805	Homo sapiens	91.98	0.00e+00	985.00
IUUC-Hvu-047122	Hordeum vulgare	39.02	7.00e-03	33.90
IUUC-Itr-049048	Ictidomys tridecemlineatus	91.42	0.00e+00	1004.00
IUUC-Lch-049686	Latimeria chalumnae	80.33	0.00e+00	846.00
IUUC-Lpe-051639	Leersia perrieri	29.23	1.70e-01	30.80
IUUC-Loc-051745	Lepisosteus oculatus	73.27	0.00e+00	723.00
IUUC-Lma-053042	Leptosphaeria maculans	24.17	9.90e-01	30.80
IUUC-Laf-054124	Loxodonta africana	89.94	0.00e+00	982.00
IUUC-Mcc-055175	Macaca mulatta	91.60	0.00e+00	983.00
IUUC-Meu-056557	Macropus eugenii	90.72	0.00e+00	991.00
IUUC-Mla-136541	Melampsora laricipopulina	52.17	8.40e+00	23.50
IUUC-Mga-059214	Meleagris gallopavo	95.90	0.00e+00	1051.00
IUUC-Mmr-060613	Microcebus murinus	76.49	0.00e+00	762.00
IUUC-Mdo-062788	Monodelphis domestica	90.91	0.00e+00	959.00
IUUC-Mmu-064333	Mus musculus	89.55	0.00e+00	967.00
IUUC-Mpu-066048	Mustela putorius furo	91.60	0.00e+00	983.00
IUUC-Mlu-067430	Myotis lucifugus	91.23	0.00e+00	959.00
IUUC-Nle-069086	Nomascus leucogenys	91.60	0.00e+00	1005.00
IUUC-Opr-070312	Ochotona princeps	87.50	0.00e+00	934.00
IUUC-Ont-072299	Oreochromis niloticus	65.07	0.00e+00	642.00
IUUC-Ocu-074123	Oryctolagus cuniculus	86.19	0.00e+00	920.00
IUUC-Ola-086934	Oryzias latipes	67.78	0.00e+00	659.00
IUUC-Oga-088535	Otolemur garnettii	91.23	0.00e+00	1004.00
IUUC-Oar-089875	Ovis aries	91.04	0.00e+00	981.00
IUUC-Ptr-090541	Pan troglodytes	91.98	0.00e+00	985.00
IUUC-Pan-092416	Papio anubis	91.60	0.00e+00	983.00
IUUC-Psi-092960	Pelodiscus sinensis	89.74	0.00e+00	981.00
IUUC-Pma-094222	Petromyzon marinus	50.45	9.00e-137	479.00
IUUC-Pfo-096930	Poecilia formosa	64.07	0.00e+00	651.00
IUUC-Pab-098659	Pongo abelii	91.79	0.00e+00	984.00
IUUC-Pop-098820	Populus trichocarpa	41.18	1.20e-01	30.40
IUUC-Pca-100222	Procavia capensis	87.90	0.00e+00	964.00
IUUC-Pva-102387	Pteropus vampyrus	90.67	0.00e+00	974.00
IUUC-Rno-105698	Rattus norvegicus	89.74	0.00e+00	967.00
IUUC-Sha-107234	Sarcophilus harrisii	89.98	0.00e+00	959.00
IUUC-Sar-113698	Sorex araneus	84.89	0.00e+00	869.00
IUUC-Ssc-115985	Sus scrofa	90.49	0.00e+00	993.00
IUUC-Tru-118441	Takifugu rubripes	59.85	3.00e-152	531.00
IUUC-Tsy-119163	Tarsius syrichta	85.26	0.00e+00	931.00
IUUC-Tni-120436	Tetraodon nigroviridis	66.11	0.00e+00	639.00
IUUC-Tae-124846	Triticum aestivum	32.65	1.60e-01	28.90
IUUC-Tbe-127353	Tupaia belangeri	91.79	0.00e+00	984.00
IUUC-Ttr-128907	Tursiops truncatus	91.23	0.00e+00	959.00
IUUC-Vpa-130140	Vicugna pacos	91.42	0.00e+00	984.00
IUUC-Xtr-132817	Xenopus tropicalis	79.33	0.00e+00	860.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence