iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	44.85	1.00e-165	581.00	IUUC-Mmu-063153
E3 activity/RING/RING	50.19	0.00e+00	769.00	IUUC-Dre-028844

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MRASIPPGIR VVRGPNWIWS NQDDGEGHVG TVCEIGRCGS THSPENTVVV NWDSGHRTNY 60
RVGYQNQYDL IIVDNAQVGV RHSNVVCDGC SKAGIAGIVF KCAQCPNYHL CAYCYAEDLH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAATTCGTC CATTTCGGCC GCTCTTTTCA TCACACGCTA CCGAACATGA ATACAAATAA 60
GTAATCACTC CGCGATTGAC AACTATGTAA ATTTATGGAC TGCCAAAAAT AAAATAATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001370--BIR_rpt
IPR010606--Mib_Herc2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR000433--Znf_ZZ

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS51416--MIB_HERC2
PS50089--ZF_RING_2
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF12796--Ank_2
PF06701--MIB_HERC2
PF00569--ZZ

SMART

SM00248--ANK
SM00184--RING
SM00291--ZnF_ZZ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0031430--C:M band
GO:0030018--C:Z disc
GO:0032038--F:myosin II heavy chain binding
GO:0032033--F:myosin II light chain binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0046716--P:muscle cell cellular homeostasis
GO:0007520--P:myoblast fusion
GO:0000209--P:protein polyubiquitination

KEGG

dme:Dmel_CG17492

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001839	Ailuropoda melanoleuca	47.41	1.00e-172	599.00
IUUC-Apl-003333	Anas platyrhynchos	44.87	3.00e-162	564.00
IUUC-Ame-011227	Astyanax mexicanus	52.34	0.00e+00	747.00
IUUC-Bta-012993	Bos taurus	47.32	0.00e+00	634.00
IUUC-Cja-019653	Callithrix jacchus	43.36	0.00e+00	644.00
IUUC-Cfa-020044	Canis familiaris	47.84	0.00e+00	634.00
IUUC-Cpo-021836	Cavia porcellus	47.85	0.00e+00	653.00
IUUC-Csa-023940	Chlorocebus sabaeus	47.68	0.00e+00	649.00
IUUC-Dre-028844	Danio rerio	50.19	0.00e+00	773.00
IUUC-Dor-030915	Dipodomys ordii	42.95	7.00e-96	344.00
IUUC-Dse-031315	Dothistroma septosporum	39.13	3.00e-06	47.00
IUUC-Ete-033045	Echinops telfairi	45.25	1.00e-147	516.00
IUUC-Eca-034009	Equus caballus	47.43	2.00e-179	621.00
IUUC-Eeu-035321	Erinaceus europaeus	54.55	2.00e-79	289.00
IUUC-Fal-036757	Ficedula albicollis	47.16	0.00e+00	731.00
IUUC-Gmo-039304	Gadus morhua	53.48	0.00e+00	727.00
IUUC-Gga-040651	Gallus gallus	46.36	0.00e+00	731.00
IUUC-Gac-042061	Gasterosteus aculeatus	49.17	0.00e+00	736.00
IUUC-Hsa-046523	Homo sapiens	47.40	0.00e+00	642.00
IUUC-Itr-048215	Ictidomys tridecemlineatus	46.08	2.00e-172	598.00
IUUC-Lch-049427	Latimeria chalumnae	46.12	0.00e+00	729.00
IUUC-Loc-052166	Lepisosteus oculatus	49.50	0.00e+00	781.00
IUUC-Laf-054174	Loxodonta africana	44.74	4.00e-154	537.00
IUUC-Mcc-055748	Macaca mulatta	47.82	0.00e+00	652.00
IUUC-Meu-056351	Macropus eugenii	42.81	3.00e-67	249.00
IUUC-Mla-058995	Melampsora laricipopulina	30.77	6.00e-07	45.40
IUUC-Mga-059882	Meleagris gallopavo	36.80	9.00e-135	473.00
IUUC-Mmr-061388	Microcebus murinus	44.11	4.00e-156	544.00
IUUC-Mdo-061981	Monodelphis domestica	47.29	0.00e+00	712.00
IUUC-Mmu-063153	Mus musculus	43.99	6.00e-163	567.00
IUUC-Mpu-066551	Mustela putorius furo	46.76	5.00e-175	607.00
IUUC-Ont-072414	Oreochromis niloticus	49.94	0.00e+00	761.00
IUUC-Osa-085300	Oryza sativa	30.05	6.00e-14	71.60
IUUC-Ola-086715	Oryzias latipes	53.31	0.00e+00	758.00
IUUC-Oga-088898	Otolemur garnettii	47.54	0.00e+00	650.00
IUUC-Oar-089265	Ovis aries	41.06	1.00e-133	469.00
IUUC-Pan-092360	Papio anubis	47.68	0.00e+00	646.00
IUUC-Psi-093964	Pelodiscus sinensis	46.53	0.00e+00	701.00
IUUC-Pma-094121	Petromyzon marinus	35.75	5.00e-139	487.00
IUUC-Pfo-096821	Poecilia formosa	49.38	0.00e+00	762.00
IUUC-Pab-098440	Pongo abelii	39.43	4.00e-99	355.00
IUUC-Pca-100806	Procavia capensis	41.24	1.00e-75	277.00
IUUC-Pva-102667	Pteropus vampyrus	44.08	7.00e-124	437.00
IUUC-Rno-105681	Rattus norvegicus	47.52	0.00e+00	631.00
IUUC-Spo-108118	Schizosaccharomyces pombe	28.27	8.00e-07	48.10
IUUC-Ssc-116370	Sus scrofa	48.79	0.00e+00	629.00
IUUC-Tgu-116853	Taeniopygia guttata	47.42	0.00e+00	730.00
IUUC-Tru-118714	Takifugu rubripes	43.61	0.00e+00	840.00
IUUC-Tni-119764	Tetraodon nigroviridis	52.12	0.00e+00	757.00
IUUC-Tme-127010	Tuber melanosporum	37.70	8.00e-06	45.10
IUUC-Xtr-132967	Xenopus tropicalis	40.55	0.00e+00	776.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence