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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-031640
Ensembl Protein ID FBpp0079496
UniProt Accession Q9VL72; Q2PDU7; Q95ST4; SMRCD_DROME
Genbank Protein ID AAF52824.1; AAL28145.1
Protein Name SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 homolog; Enhancer trap locus homolog 1
Genbank Nucleotide ID AE014134; AY060597
Gene Name Etl1; CG5899
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0032157 FBtr0079901 FBpp0079496
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
CPLMdbPAFUniProt
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/CUE 38.36 6.00e-99 357.00 IUUC-Sce-106399
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs (By similarity).
 DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs (By similarity).
Protein Sequence
(Fasta)
MSDSTVAASA SASASSSAKS SLSDLRQFRI NKNASSVVAS PSRTERVPGK KRIQVMADSD 60
SDGNDSQTPK KTKLELTVKE KEERYMAAAK ISPHFDTMAI QESLSRTNWD VAASVRYLRE 120
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Protein Fasta Sequence


>IUUC-Dme-031640|UBD,CUE|Drosophila melanogaster
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Nucleotide Sequence
(Fasta)
TATCGGGATA ATCAAACGGC CGCACTAGCA TGCGAATATT CACAAATACC AACTTAAGAT 60
TGTAGGAGTT GCAAACAGAA TTTGTTAATA AGGACTGACA GATTGCCAGG AAGCGTTTCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031640|UBD,CUE|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
Pfam

PF00271--Helicase_C
PF00176--SNF2_N
SMART

SM00487--DEXDc
SM00490--HELICc
Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0004386--F:helicase activity
GO:0016569--P:covalent chromatin modification
GO:0050829--P:defense response to Gram-negative bacterium
GO:0006281--P:DNA repair
GO:0045089--P:positive regulation of innate immune response
KEGG dme:Dmel_CG5899
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000567 Aegilops tauschii 39.11 9.00e-100 357.00
IUUC-Aml-002063 Ailuropoda melanoleuca 45.54 7.00e-160 557.00
IUUC-Atr-003078 Amborella trichopoda 36.87 3.00e-104 372.00
IUUC-Apl-003860 Anas platyrhynchos 46.17 1.00e-164 572.00
IUUC-Aca-004485 Anolis carolinensis 46.63 8.00e-164 570.00
IUUC-Aly-006561 Arabidopsis lyrata 39.77 7.00e-104 370.00
IUUC-Ath-006832 Arabidopsis thaliana 39.55 5.00e-104 371.00
IUUC-Ago-007758 Ashbya gossypii 40.93 9.00e-113 400.00
IUUC-Acl-008226 Aspergillus clavatus 41.62 3.00e-114 405.00
IUUC-Afl-008556 Aspergillus flavus 42.46 2.00e-107 383.00
IUUC-Afu-008799 Aspergillus fumigatus 41.42 1.00e-113 403.00
IUUC-Ani-009127 Aspergillus nidulans 40.11 6.00e-103 368.00
IUUC-Ang-009676 Aspergillus niger 41.73 6.00e-112 398.00
IUUC-Aor-010184 Aspergillus oryzae 42.57 2.00e-108 386.00
IUUC-Ate-010559 Aspergillus terreus 36.22 5.00e-112 398.00
IUUC-Ame-011933 Astyanax mexicanus 44.48 1.00e-148 520.00
IUUC-Bgr-012028 Blumeria graminis 35.89 3.00e-52 198.00
IUUC-Bta-012963 Bos taurus 45.23 5.00e-159 554.00
IUUC-Bci-013670 Botrytis cinerea 37.97 6.00e-100 358.00
IUUC-Bdi-014286 Brachypodium distachyon 39.67 6.00e-102 364.00
IUUC-Bol-016519 Brassica oleracea 39.96 1.00e-103 370.00
IUUC-Bra-017239 Brassica rapa 39.96 4.00e-104 371.00
IUUC-Cel-018253 Caenorhabditis elegans 42.45 6.00e-136 477.00
IUUC-Cja-019465 Callithrix jacchus 45.54 7.00e-160 557.00
IUUC-Cfa-020637 Canis familiaris 45.69 2.00e-160 559.00
IUUC-Cpo-021822 Cavia porcellus 45.69 3.00e-159 555.00
IUUC-Csa-023315 Chlorocebus sabaeus 45.54 8.00e-160 556.00
IUUC-Cin-025444 Ciona intestinalis 44.04 2.00e-149 521.00
IUUC-Cgl-026383 Colletotrichum gloeosporioides 31.45 6.00e-86 311.00
IUUC-Cne-027090 Cryptococcus neoformans 34.80 4.00e-100 358.00
IUUC-Dre-028385 Danio rerio 43.65 1.00e-138 486.00
IUUC-Dno-028932 Dasypus novemcinctus 45.54 1.00e-159 556.00
IUUC-Dse-031394 Dothistroma septosporum 38.07 9.00e-92 330.00
IUUC-Eca-033276 Equus caballus 45.38 1.00e-160 560.00
IUUC-Fca-035936 Felis catus 44.77 5.00e-156 544.00
IUUC-Fal-037636 Ficedula albicollis 46.63 8.00e-165 573.00
IUUC-Fso-038229 Fusarium solani 31.81 4.00e-92 332.00
IUUC-Gmo-039654 Gadus morhua 44.34 4.00e-135 474.00
IUUC-Ggr-039922 Gaeumannomyces graminis 32.25 9.00e-82 298.00
IUUC-Gga-040646 Gallus gallus 46.15 5.00e-162 564.00
IUUC-Gac-042320 Gasterosteus aculeatus 45.25 2.00e-141 495.00
IUUC-Gma-042832 Glycine max 40.11 9.00e-107 380.00
IUUC-Ggo-044875 Gorilla gorilla 40.15 1.00e-131 463.00
IUUC-Hsa-046992 Homo sapiens 45.38 2.00e-160 559.00
IUUC-Hvu-047408 Hordeum vulgare 39.30 2.00e-99 356.00
IUUC-Itr-047881 Ictidomys tridecemlineatus 48.20 2.00e-145 508.00
IUUC-Kpa-049212 Komagataella pastoris 41.12 8.00e-117 414.00
IUUC-Lpe-050987 Leersia perrieri 39.52 7.00e-103 367.00
IUUC-Loc-052272 Lepisosteus oculatus 44.72 3.00e-152 531.00
IUUC-Lma-053118 Leptosphaeria maculans 39.82 1.00e-108 387.00
IUUC-Laf-053436 Loxodonta africana 45.08 1.00e-154 540.00
IUUC-Mcc-055209 Macaca mulatta 45.54 1.00e-159 556.00
IUUC-Meu-056545 Macropus eugenii 52.22 8.00e-26 112.00
IUUC-Mor-056994 Magnaporthe oryzae 32.68 1.00e-83 303.00
IUUC-Mpo-057305 Magnaporthe poae 32.35 1.00e-85 310.00
IUUC-Mtr-058432 Medicago truncatula 40.30 6.00e-106 377.00
IUUC-Mla-058972 Melampsora laricipopulina 36.08 4.00e-109 388.00
IUUC-Mga-059572 Meleagris gallopavo 46.33 1.00e-148 520.00
IUUC-Mvi-060209 Microbotryum violaceum 35.47 2.00e-115 409.00
IUUC-Mmr-061416 Microcebus murinus 44.05 2.00e-134 471.00
IUUC-Mdo-062869 Monodelphis domestica 45.54 3.00e-162 565.00
IUUC-Mmu-064272 Mus musculus 45.69 9.00e-154 536.00
IUUC-Mac-064963 Musa acuminata 40.47 6.00e-101 361.00
IUUC-Mpu-065755 Mustela putorius furo 45.69 2.00e-160 559.00
IUUC-Mlu-067604 Myotis lucifugus 45.54 3.00e-165 575.00
IUUC-Nfi-068310 Neosartorya fischeri 41.10 2.00e-114 406.00
IUUC-Ncr-068841 Neurospora crassa 31.85 6.00e-92 331.00
IUUC-Nle-069227 Nomascus leucogenys 45.38 2.00e-160 559.00
IUUC-Opr-071088 Ochotona princeps 42.00 2.00e-143 503.00
IUUC-Ont-072291 Oreochromis niloticus 45.75 3.00e-142 498.00
IUUC-Oan-073460 Ornithorhynchus anatinus 46.31 1.00e-167 582.00
IUUC-Ocu-074811 Oryctolagus cuniculus 45.69 3.00e-160 558.00
IUUC-Oba-075463 Oryza barthii 39.74 4.00e-103 367.00
IUUC-Obr-076342 Oryza brachyantha 39.55 1.00e-104 373.00
IUUC-Ogu-078837 Oryza glumaepatula 39.74 3.00e-103 369.00
IUUC-Oin-079623 Oryza indica 39.74 3.00e-103 369.00
IUUC-Ome-081105 Oryza meridionalis 39.74 2.00e-103 369.00
IUUC-Oni-082598 Oryza nivara 39.74 3.00e-103 369.00
IUUC-Opu-084040 Oryza punctata 39.74 1.00e-103 369.00
IUUC-Oru-084219 Oryza rufipogon 39.74 3.00e-103 369.00
IUUC-Osa-085461 Oryza sativa 39.74 1.00e-103 370.00
IUUC-Ola-087307 Oryzias latipes 45.28 5.00e-134 471.00
IUUC-Olu-087812 Ostreococcus lucimarinus 36.62 1.00e-89 323.00
IUUC-Oga-089064 Otolemur garnettii 45.54 1.00e-158 553.00
IUUC-Oar-090054 Ovis aries 45.38 2.00e-159 555.00
IUUC-Ptr-091228 Pan troglodytes 45.54 6.00e-160 557.00
IUUC-Pan-092769 Papio anubis 45.44 1.00e-141 496.00
IUUC-Psi-093202 Pelodiscus sinensis 46.24 1.00e-163 570.00
IUUC-Pma-094725 Petromyzon marinus 37.28 8.00e-157 546.00
IUUC-Pno-095130 Phaeosphaeria nodorum 39.88 1.00e-101 364.00
IUUC-Ppa-095559 Physcomitrella patens 39.89 2.00e-108 385.00
IUUC-Pfo-096546 Poecilia formosa 44.62 1.00e-146 513.00
IUUC-Pab-097698 Pongo abelii 45.38 3.00e-160 558.00
IUUC-Pop-099986 Populus trichocarpa 42.46 2.00e-110 392.00
IUUC-Ppe-101649 Prunus persica 40.40 4.00e-110 391.00
IUUC-Pva-102138 Pteropus vampyrus 44.95 3.00e-156 545.00
IUUC-Pgr-103272 Puccinia graminis 35.09 8.00e-108 384.00
IUUC-Ptt-103880 Puccinia triticina 34.98 3.00e-114 405.00
IUUC-Pte-104260 Pyrenophora teres 40.00 3.00e-104 372.00
IUUC-Pyt-104532 Pyrenophora triticirepentis 35.58 9.00e-79 288.00
IUUC-Rno-105903 Rattus norvegicus 46.00 9.00e-156 543.00
IUUC-Sce-106399 Saccharomyces cerevisiae 38.36 5.00e-106 378.00
IUUC-Sha-106783 Sarcophilus harrisii 45.69 2.00e-158 552.00
IUUC-Sja-107887 Schizosaccharomyces japonicus 41.19 5.00e-129 454.00
IUUC-Spo-108154 Schizosaccharomyces pombe 37.92 1.00e-131 464.00
IUUC-Smo-108759 Selaginella moellendorffii 39.38 6.00e-107 380.00
IUUC-Sit-110023 Setaria italica 39.18 2.00e-102 366.00
IUUC-Sly-111423 Solanum lycopersicum 39.55 4.00e-102 364.00
IUUC-Sbi-114688 Sorghum bicolor 36.09 5.00e-104 371.00
IUUC-Sre-114983 Sporisorium reilianum 34.32 2.00e-103 370.00
IUUC-Ssc-116030 Sus scrofa 45.54 6.00e-160 557.00
IUUC-Tgu-117451 Taeniopygia guttata 45.92 1.00e-159 555.00
IUUC-Tru-118600 Takifugu rubripes 44.60 8.00e-130 457.00
IUUC-Tsy-119130 Tarsius syrichta 39.04 2.00e-120 426.00
IUUC-Tni-119758 Tetraodon nigroviridis 43.62 8.00e-133 467.00
IUUC-Tca-121797 Theobroma cacao 41.87 1.00e-109 389.00
IUUC-Tre-121883 Trichoderma reesei 32.30 9.00e-85 307.00
IUUC-Tvi-122333 Trichoderma virens 32.59 2.00e-94 340.00
IUUC-Tae-122848 Triticum aestivum 39.11 1.00e-99 357.00
IUUC-Tur-126594 Triticum urartu 39.11 5.00e-99 354.00
IUUC-Tme-127106 Tuber melanosporum 40.44 1.00e-113 403.00
IUUC-Tbe-127911 Tupaia belangeri 47.35 4.00e-130 458.00
IUUC-Ttr-128597 Tursiops truncatus 44.90 7.00e-159 553.00
IUUC-Uma-129321 Ustilago maydis 34.96 8.00e-105 374.00
IUUC-Vpa-130686 Vicugna pacos 40.71 4.00e-123 435.00
IUUC-Vvi-131046 Vitis vinifera 41.46 2.00e-108 385.00
IUUC-Xtr-132740 Xenopus tropicalis 43.45 6.00e-148 517.00
IUUC-Xma-134260 Xiphophorus maculatus 44.41 8.00e-147 513.00
IUUC-Yli-134634 Yarrowia lipolytica 42.37 4.00e-118 418.00
IUUC-Zma-135493 Zea mays 37.50 1.00e-102 367.00
Created Date 25-Jun-2017

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