iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-060013

Ensembl Protein ID

ENSMGAP00000006305.2

UniProt Accession

G1N3K5; G1N3K5_MELGA

Protein Name

Uncharacterized protein

Gene Name

VAV3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000006230.2	ENSMGAT00000007045.2	ENSMGAP00000006298.2
ENSMGAG00000006230.2	ENSMGAT00000007053.2	ENSMGAP00000006305.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-14	53.6	792	843

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ yd+ a +  eL+l kGdvv++   +   +gW++g  e +g+ G fP+ +ve+
   Q: 792  IARYDFCARDMRELSLLKGDVVKIY-TKMSANGWWRG--EVNGRVGWFPSTYVEE 843
           578*********************9.999999*****..9*************85 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

IACWVQCGQW LISCKVLPPN HRVTWDTAQV FDLAQTLRDG VLLCQLLNNL RSHSINLKEI 60
NLRPQMSQFL CLKNIRTFLS ACCEIFGMKK SELFEAFDLF DVRDFGKVIE TLSKLSRTPI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGCTTGCT GGGTGGTGAG TGTTGGGCTC TGGGACATTC AGGGCAGCTG TAGGCAGCAC 60
TGGTTGTGCT CTCTGTCAGA AGACATTCTC ACCCCAGGCT GTGTCTTTTT TTTTTTTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
IPR003096--SM22_calponin

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00888--SM22CALPONIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001362	Ailuropoda melanoleuca	82.51	0.00e+00	1374.00
IUUC-Apl-003734	Anas platyrhynchos	92.06	0.00e+00	1404.00
IUUC-Aca-004477	Anolis carolinensis	81.69	0.00e+00	1379.00
IUUC-Ath-007340	Arabidopsis thaliana	50.00	1.00e-02	34.30
IUUC-Ame-011279	Astyanax mexicanus	65.25	0.00e+00	1083.00
IUUC-Bta-012722	Bos taurus	81.98	0.00e+00	1372.00
IUUC-Cel-018578	Caenorhabditis elegans	29.26	2.00e-97	350.00
IUUC-Cja-018941	Callithrix jacchus	82.52	0.00e+00	1365.00
IUUC-Cfa-020266	Canis familiaris	82.02	0.00e+00	1216.00
IUUC-Cpo-021966	Cavia porcellus	81.09	0.00e+00	1169.00
IUUC-Csa-023892	Chlorocebus sabaeus	81.63	0.00e+00	1251.00
IUUC-Dre-028199	Danio rerio	65.28	0.00e+00	1099.00
IUUC-Dno-029474	Dasypus novemcinctus	82.51	0.00e+00	1380.00
IUUC-Eca-033961	Equus caballus	82.28	0.00e+00	1234.00
IUUC-Eeu-034719	Erinaceus europaeus	60.99	0.00e+00	942.00
IUUC-Fca-036572	Felis catus	82.54	0.00e+00	1350.00
IUUC-Fal-036802	Ficedula albicollis	89.36	0.00e+00	1518.00
IUUC-Gmo-039409	Gadus morhua	68.48	0.00e+00	1155.00
IUUC-Gga-040884	Gallus gallus	93.26	0.00e+00	1550.00
IUUC-Gac-041395	Gasterosteus aculeatus	70.45	0.00e+00	1216.00
IUUC-Ggo-044460	Gorilla gorilla	79.58	0.00e+00	1175.00
IUUC-Hsa-046099	Homo sapiens	80.21	0.00e+00	1368.00
IUUC-Itr-048144	Ictidomys tridecemlineatus	78.65	0.00e+00	1185.00
IUUC-Lch-049650	Latimeria chalumnae	76.89	1.00e-95	341.00
IUUC-Loc-052487	Lepisosteus oculatus	71.33	0.00e+00	1212.00
IUUC-Laf-054564	Loxodonta africana	82.62	0.00e+00	1377.00
IUUC-Mcc-054622	Macaca mulatta	79.98	0.00e+00	1364.00
IUUC-Meu-056680	Macropus eugenii	76.06	0.00e+00	1243.00
IUUC-Mmr-061251	Microcebus murinus	78.92	0.00e+00	1379.00
IUUC-Mdo-061875	Monodelphis domestica	82.74	0.00e+00	1386.00
IUUC-Mmu-063735	Mus musculus	82.15	0.00e+00	1389.00
IUUC-Mpu-065856	Mustela putorius furo	82.86	0.00e+00	1382.00
IUUC-Mlu-068108	Myotis lucifugus	79.52	0.00e+00	1321.00
IUUC-Nle-069863	Nomascus leucogenys	78.87	0.00e+00	1338.00
IUUC-Opr-070372	Ochotona princeps	72.50	0.00e+00	890.00
IUUC-Ont-072286	Oreochromis niloticus	71.39	0.00e+00	1205.00
IUUC-Ocu-074194	Oryctolagus cuniculus	82.15	0.00e+00	1365.00
IUUC-Ola-086336	Oryzias latipes	70.27	0.00e+00	1201.00
IUUC-Oga-089104	Otolemur garnettii	59.32	0.00e+00	988.00
IUUC-Oar-089272	Ovis aries	81.86	0.00e+00	1410.00
IUUC-Ptr-090652	Pan troglodytes	80.31	0.00e+00	1358.00
IUUC-Pan-092550	Papio anubis	78.86	0.00e+00	1198.00
IUUC-Psi-093784	Pelodiscus sinensis	82.16	0.00e+00	1283.00
IUUC-Pfo-097308	Poecilia formosa	69.53	0.00e+00	1203.00
IUUC-Pab-098698	Pongo abelii	80.14	0.00e+00	1357.00
IUUC-Pva-102262	Pteropus vampyrus	81.89	0.00e+00	1315.00
IUUC-Rno-105421	Rattus norvegicus	81.56	0.00e+00	1383.00
IUUC-Sha-107325	Sarcophilus harrisii	83.25	0.00e+00	1415.00
IUUC-Sar-113456	Sorex araneus	77.19	0.00e+00	1296.00
IUUC-Ssc-115338	Sus scrofa	57.65	0.00e+00	903.00
IUUC-Tgu-116595	Taeniopygia guttata	90.10	0.00e+00	1479.00
IUUC-Tru-117884	Takifugu rubripes	65.26	0.00e+00	1137.00
IUUC-Tsy-119429	Tarsius syrichta	82.28	0.00e+00	790.00
IUUC-Tni-119951	Tetraodon nigroviridis	67.65	0.00e+00	1121.00
IUUC-Tbe-127995	Tupaia belangeri	75.87	1.00e-160	559.00
IUUC-Ttr-128281	Tursiops truncatus	82.51	0.00e+00	1373.00
IUUC-Vpa-130066	Vicugna pacos	47.26	1.00e-34	140.00
IUUC-Xtr-132427	Xenopus tropicalis	70.82	0.00e+00	1226.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence