iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000004070.1	ENSPSIT00000004347.1	ENSPSIP00000004324.1
ENSPSIG00000004070.1	ENSPSIT00000004351.1	ENSPSIP00000004328.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.20e-09	36.5	240	282

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl+++++g  +++lpC H++h  C+ +w     +++++ +CP+C+
   Q: 240  CAICLDEYEEGdrLRILPCAHAYHCRCVDHW-----LTQTKKTCPVCK 282
           ********5544499****************.....89*********7 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

LRAVSRLTLS PLQDSTSSVA TLLLQACLLL PPVAAYIHAV TDHNFTMDFS DLPALFGVLL 60
PREGLVGYLI EAKPSNACEP IEGPPGPSNA THFIALIRRY NCNFDIKVWH AQQAGFHAAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGAGGGCTG TCTCCAGGCT CACGCTCTCC CCTCTACAGG ACTCCACCAG CTGATAGTAT 60
GCTGCTCAAG CATGCCTTCC CCAGCTCAGT TGCAACCCTG CTGCTCCAAG CCTGCCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045786--P:negative regulation of cell cycle
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000889	Aegilops tauschii	27.27	4.00e-19	89.40
IUUC-Aml-001413	Ailuropoda melanoleuca	64.20	4.00e-93	334.00
IUUC-Bta-012651	Bos taurus	66.82	9.00e-90	322.00
IUUC-Bdi-014479	Brachypodium distachyon	35.77	1.00e-28	119.00
IUUC-Bol-015396	Brassica oleracea	32.20	1.00e-23	103.00
IUUC-Cja-018953	Callithrix jacchus	66.14	5.00e-101	360.00
IUUC-Cfa-020540	Canis familiaris	55.73	2.00e-76	278.00
IUUC-Cpo-022372	Cavia porcellus	60.46	6.00e-107	380.00
IUUC-Csa-023070	Chlorocebus sabaeus	61.24	3.00e-106	377.00
IUUC-Dre-028786	Danio rerio	60.62	3.00e-87	315.00
IUUC-Dno-028877	Dasypus novemcinctus	62.21	6.00e-103	366.00
IUUC-Dor-030128	Dipodomys ordii	55.56	1.00e-91	329.00
IUUC-Eca-033699	Equus caballus	65.49	1.00e-98	352.00
IUUC-Eeu-034819	Erinaceus europaeus	59.48	9.00e-101	359.00
IUUC-Fca-036168	Felis catus	66.27	1.00e-99	355.00
IUUC-Gac-041339	Gasterosteus aculeatus	61.78	7.00e-85	306.00
IUUC-Gma-043776	Glycine max	33.70	3.00e-28	119.00
IUUC-Ggo-045113	Gorilla gorilla	62.05	3.00e-105	374.00
IUUC-Hsa-046476	Homo sapiens	62.25	2.00e-105	375.00
IUUC-Itr-047953	Ictidomys tridecemlineatus	60.98	2.00e-107	381.00
IUUC-Lch-050034	Latimeria chalumnae	64.80	9.00e-111	392.00
IUUC-Loc-051914	Lepisosteus oculatus	67.34	6.00e-91	327.00
IUUC-Laf-053687	Loxodonta africana	61.72	4.00e-102	364.00
IUUC-Mcc-055879	Macaca mulatta	61.76	1.00e-106	379.00
IUUC-Meu-056408	Macropus eugenii	67.73	1.00e-87	316.00
IUUC-Mmr-060656	Microcebus murinus	60.91	9.00e-107	379.00
IUUC-Mdo-062795	Monodelphis domestica	66.15	2.00e-102	365.00
IUUC-Mmu-063722	Mus musculus	60.59	2.00e-110	391.00
IUUC-Mpu-066094	Mustela putorius furo	61.59	2.00e-103	369.00
IUUC-Mlu-067350	Myotis lucifugus	65.10	2.00e-98	352.00
IUUC-Nle-069971	Nomascus leucogenys	62.05	3.00e-106	377.00
IUUC-Opr-070716	Ochotona princeps	59.11	1.00e-64	239.00
IUUC-Ocu-074157	Oryctolagus cuniculus	60.59	5.00e-105	374.00
IUUC-Oga-089169	Otolemur garnettii	61.04	7.00e-107	380.00
IUUC-Oar-089216	Ovis aries	65.49	2.00e-102	365.00
IUUC-Ptr-091493	Pan troglodytes	62.05	3.00e-105	374.00
IUUC-Pan-092215	Papio anubis	60.91	7.00e-106	376.00
IUUC-Pfo-097514	Poecilia formosa	61.72	1.00e-83	302.00
IUUC-Pab-097739	Pongo abelii	57.49	4.00e-102	364.00
IUUC-Pca-100609	Procavia capensis	61.76	3.00e-98	351.00
IUUC-Pva-102834	Pteropus vampyrus	62.09	2.00e-103	368.00
IUUC-Rno-106080	Rattus norvegicus	60.71	7.00e-106	376.00
IUUC-Sce-106402	Saccharomyces cerevisiae	35.96	4.00e-08	52.80
IUUC-Sha-106787	Sarcophilus harrisii	66.93	3.00e-101	360.00
IUUC-Sar-113580	Sorex araneus	52.94	2.00e-75	275.00
IUUC-Sbi-114522	Sorghum bicolor	30.69	8.00e-29	121.00
IUUC-Ssc-115900	Sus scrofa	61.56	2.00e-106	378.00
IUUC-Tni-120357	Tetraodon nigroviridis	63.56	1.00e-91	329.00
IUUC-Tae-125403	Triticum aestivum	34.48	2.00e-31	130.00
IUUC-Tur-126455	Triticum urartu	30.65	8.00e-28	117.00
IUUC-Tbe-127812	Tupaia belangeri	66.82	4.00e-90	323.00
IUUC-Ttr-128409	Tursiops truncatus	66.82	1.00e-89	322.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence