PTM - CPLM Gene Name UniProt ID Type Position Code AUP1 Q9Y679 Ubiquitination 316 K AUP1 Q9Y679 Ubiquitination 209 K AUP1 Q9Y679 Ubiquitination 330 K AUP1 Q9Y679 Ubiquitination 425 K AUP1 Q9Y679 Ubiquitination 443 K AUP1 Q9Y679 Ubiquitination 456 K AUP1 Q9Y679 Ubiquitination 335 K

PTM - dbPAF Gene Name UniProt ID Position Type Species AUP1 Q9Y679 220 T Homo sapiens(Human) AUP1 Q9Y679 326 T Homo sapiens(Human) AUP1 Q9Y679 346 S Homo sapiens(Human) AUP1 Q9Y679 349 S Homo sapiens(Human) AUP1 Q9Y679 350 S Homo sapiens(Human) AUP1 Q9Y679 354 S Homo sapiens(Human) AUP1 Q9Y679 358 S Homo sapiens(Human) AUP1 Q9Y679 365 T Homo sapiens(Human) AUP1 Q9Y679 420 T Homo sapiens(Human) AUP1 Q9Y679 422 S Homo sapiens(Human) AUP1 Q9Y679 424 S Homo sapiens(Human) AUP1 Q9Y679 428 S Homo sapiens(Human) AUP1 Q9Y679 429 S Homo sapiens(Human) AUP1 Q9Y679 433 T Homo sapiens(Human) AUP1 Q9Y679 437 T Homo sapiens(Human) AUP1 Q9Y679 451 S Homo sapiens(Human) AUP1 Q9Y679 460 Y Homo sapiens(Human) AUP1 Q9Y679 462 Y Homo sapiens(Human) AUP1 Q9Y679 5 S Homo sapiens(Human) AUP1 Q9Y679 68 T Homo sapiens(Human) AUP1 Q9Y679 82 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9Y679 S5-p Phosphorylation ___MELPsGPGPERL Q9Y679 T68-p Phosphorylation LRRFVVRtMCAVLGL Q9Y679 S82-p Phosphorylation LVARQEDsGLRDHSV Q9Y679 T220-p Phosphorylation ASTRLPPtPLLLFPE Q9Y679 T326-p Phosphorylation GQTGTRLtPADkAEH Q9Y679 S346-p Phosphorylation HPRLRPQsAQssFPP Q9Y679 S349-p Phosphorylation LRPQsAQssFPPsPG Q9Y679 S350-p Phosphorylation RPQsAQssFPPsPGP Q9Y679 S354-p Phosphorylation AQssFPPsPGPsPDV Q9Y679 S358-p Phosphorylation FPPsPGPsPDVQLAT Q9Y679 S422-p Phosphorylation TQSLPTAsAskFPss Q9Y679 S424-p Phosphorylation SLPTAsAskFPssGP Q9Y679 S428-p Phosphorylation AsAskFPssGPVtPQ Q9Y679 S429-p Phosphorylation sAskFPssGPVtPQP Q9Y679 T433-p Phosphorylation FPssGPVtPQPtALT Q9Y679 T437-p Phosphorylation GPVtPQPtALTFAkS Q9Y679 S451-p Phosphorylation SSWARQEsLQERkQA Q9Y679 Y460-p Phosphorylation QERkQALyEyARRRF Q9Y679 Y462-p Phosphorylation RkQALyEyARRRFTE Q9Y679 K209-ub Ubiquitination GELVESLkRFCASTR Q9Y679 K316-ub Ubiquitination RVQQLVAkELGQTGT Q9Y679 K330-ub Ubiquitination TRLtPADkAEHMkRQ Q9Y679 K335-ub Ubiquitination ADkAEHMkRQRHPRL Q9Y679 K388-ub Ubiquitination VIQRDLAkTGCVDLT Q9Y679 K413-ub Ubiquitination FMPEDITkGTQSLPT Q9Y679 K425-ub Ubiquitination LPTAsAskFPssGPV Q9Y679 K443-ub Ubiquitination PtALTFAkSSWARQE Q9Y679 K456-ub Ubiquitination QEsLQERkQALyEyA

PTM - dbPTM UniProt ID Position Code Type Resources References Q9Y679 354 S Phosphorylation Swiss-Prot 1010711 18669648 Q9Y679 358 S Phosphorylation Swiss-Prot 1010711 18669648 Q9Y679 422 S Phosphorylation Swiss-Prot 1010711 18669648 Q9Y679 429 S Phosphorylation Swiss-Prot 1010711 18669648 Q9Y679 433 T Phosphorylation Swiss-Prot 1010711 18669648;19413330 Q9Y679 354 S Phosphorylation PhosphoELM.10011 18669648 Q9Y679 358 S Phosphorylation PhosphoELM.10011 18669648 Q9Y679 422 S Phosphorylation PhosphoELM.10011 18669648 Q9Y679 428 S Phosphorylation PhosphoELM.10011 18669648 Q9Y679 429 S Phosphorylation PhosphoELM.10011 18669648 Q9Y679 365 T Phosphorylation PhosphoELM.10011 18669648 Q9Y679 433 T Phosphorylation PhosphoELM.10011 18669648 Q9Y679 209 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9Y679 316 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9Y679 330 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9Y679 335 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9Y679 425 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9Y679 443 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9Y679 354 S Phosphorylation Phosphositeplus.1010730 18669648;18691976;20068231 Q9Y679 358 S Phosphorylation Phosphositeplus.1010730 17137347;18669648 Q9Y679 429 S Phosphorylation Phosphositeplus.1010730 18669648;20068231 Q9Y679 82 S Phosphorylation Phosphositeplus.1010730 16674116 Q9Y679 326 T Phosphorylation Phosphositeplus.1010730 18691976 Q9Y679 433 T Phosphorylation Phosphositeplus.1010730 18669648;18691976;20068231 Q9Y679 68 T Phosphorylation Phosphositeplus.1010730 16674116 Q9Y679 354 S Phosphorylation HPRD 9.0 18669648,18691976,20068231 Q9Y679 358 S Phosphorylation HPRD 9.0 18669648 Q9Y679 422 S Phosphorylation HPRD 9.0 18669648 Q9Y679 428 S Phosphorylation HPRD 9.0 18669648,20068231 Q9Y679 429 S Phosphorylation HPRD 9.0 18669648,20068231 Q9Y679 326 T Phosphorylation HPRD 9.0 18691976 Q9Y679 365 T Phosphorylation HPRD 9.0 18669648 Q9Y679 433 T Phosphorylation HPRD 9.0 18669648,19413330,18691976,20068231

PTM - HPRD Symbol Position Code Type References AUP1 260 T Phosphorylation 18691976 AUP1 288 S Phosphorylation 18669648,18691976,20068231 AUP1 292 S Phosphorylation 18669648 AUP1 299 T Phosphorylation 18669648 AUP1 326 T Phosphorylation 18691976 AUP1 354 S Phosphorylation 18669648,18691976,20068231 AUP1 356 S Phosphorylation 18669648 AUP1 358 S Phosphorylation 18669648 AUP1 362 S Phosphorylation 18669648,20068231 AUP1 363 S Phosphorylation 18669648,20068231 AUP1 365 T Phosphorylation 18669648 AUP1 367 T Phosphorylation 18669648,19413330,18691976,20068231 AUP1 422 S Phosphorylation 18669648 AUP1 428 S Phosphorylation 18669648,20068231 AUP1 429 S Phosphorylation 18669648,20068231 AUP1 433 T Phosphorylation 18669648,19413330,18691976,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9Y679 365 T 18669648 HTP Phosphorylation Q9Y679 354 S 18669648 HTP Phosphorylation Q9Y679 358 S 18669648 HTP Phosphorylation Q9Y679 433 T 18669648 HTP Phosphorylation Q9Y679 429 S 18669648 HTP Phosphorylation Q9Y679 422 S 18669648 HTP Phosphorylation Q9Y679 428 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9Y679 1 N-acetylmethionine 22223895;22814378 Q9Y679 5 Phosphoserine 23186163 Q9Y679 354 Phosphoserine 18669648;18691976;20068231;23186163 Q9Y679 358 Phosphoserine 18669648 Q9Y679 429 Phosphoserine 18669648 Q9Y679 433 Phosphothreonine 18669648;18691976;23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type AUP1 IPI00001891 S 354 QSSFPPpSPGPSPD phosphorylation AUP1 IPI00001891 S 429 ASKFPSpSGPVTPQ phosphorylation AUP1 IPI00001891 T 326 QTGTRLpTPADKAE phosphorylation AUP1 IPI00001891 T 433 PSSGPVpTPQPTAL phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 550 107031 - K Ubiquitination 16196087 550 107031 - K Ubiquitination 18781797 550 107031 - K Ubiquitination 21987572 550 107031 - K Ubiquitination 21139048 550 107031 - K Ubiquitination 21890473 550 107031 - K Ubiquitination 21906983 550 107031 - K Ubiquitination 21857022 550 107031 - K Ubiquitination 22053931 550 107031 - K Ubiquitination 22505724 550 107031 - K FAT10ylation 22797925 550 107031 - K Ubiquitination 21963094 550 107031 - K Ubiquitination 23000965 550 107031 - K Ubiquitination 24039768 550 107031 - K Ubiquitination 25015289 550 107031 - K Ubiquitination 25147182

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID AUP1 Homo sapiens (Human) 316 "316,VQQLVAKELGQTG" "316:21139048,22053931" AUP1 Homo sapiens (Human) 425; 443; 330; 209; 316 "425,PTASASKFPSSGP; 443,TALTFAKSSWARQ; 330,RLTPADKAEHMKR; 209,ELVESLKRFCAST; 316,VQQLVAKELGQTG" 425:21890473; 443:21890473; 330:21890473; 209:21890473; 316:21890473 AUP1 Homo sapiens (Human) 359; 250; 143; 264; 377; 269 "359,PTASASKFPSSGP; 250,VQQLVAKELGQTG; 143,ELVESLKRFCAST; 264,RLTPADKAEHMKR; 377,TALTFAKSSWARQ; 269,DKAEHMKRQRHPR" "359:21890473,21906983; 250:21890473,21906983; 143:21890473,21906983; 264:21890473; 377:21890473,21906983; 269:21906983" AUP1 Homo sapiens (Human) 250; 143; 264; 269 "250,VQQLVAKELGQTG; 143,ELVESLKRFCAST; 264,RLTPADKAEHMKR; 269,DKAEHMKRQRHPR" "250:21890473,21906983; 143:21890473,21906983; 264:21890473; 269:21906983" AUP1 Homo sapiens (Human) 425; 443; 335; 330; 209; 316 "425,PTASASKFPSSGP; 443,TALTFAKSSWARQ; 335,DKAEHMKRQRHPR; 330,RLTPADKAEHMKR; 209,ELVESLKRFCAST; 316,VQQLVAKELGQTG" "425:21890473,21906983; 443:21890473,21906983; 335:21906983; 330:21890473; 209:21890473,21906983; 316:21890473,21906983,22053931" AUP1 Homo sapiens (Human) 307; 200; 321; 434 "307,VQQLVAKELGQTG; 200,ELVESLKRFCAST; 321,RLTPADKAEHMKR; 434,TALTFAKSSWARQ" 307:21890473; 200:21890473; 321:21890473; 434:21890473 AUP1 Homo sapiens (Human) 250; 143; 264 "250,VQQLVAKELGQTG; 143,ELVESLKRFCAST; 264,RLTPADKAEHMKR" 250:21890473; 143:21890473; 264:21890473