PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CG42306-RA CG11097 14605208 biogrid,intact exp Abd-B CG42306-RA 14605208 biogrid,intact exp CG42306-RA fz2 25294943 intact exp CG42306-RA 4E-binding protein THOR, CG8846-PA, HL08053p, Thor, isoform B 25294943 intact exp CG42306-RA CG12116, RE21057p 14605208 biogrid,intact exp CG42306-RA l(2)35Bd 14605208 biogrid,intact exp CG42306-RA zip 25294943 intact exp Lac CG42306-RA 25294943 intact exp CG42306-RA TER94 25369031,22036573 biogrid,dip exp, ortho Short stop, isoform H CG42306-RA ortho CG42306-RA RuvB-like helicase 1 ortho CG42306-RA 26S proteasome regulatory complex subunit p97, Regulatory particle non-ATPase 1 ortho CG42306-RA GH10703p, Vacuolar protein sorting 39 ortho CG42306-RA Fas-associated factor, isoform A, Fas-associated factor, isoform B, GH16914p ortho 14-3-3epsilon CG42306-RA ortho CG42306-RA sbr ortho Aph-4 CG42306-RA ortho CG42306-RA Phospholipase A2 activator protein, isoform A, Phospholipase A2 activator protein, isoform B, Phospholipase A2 activator protein, isoform C, SD05646p ortho Cpr CG42306-RA ortho Ef1alpha100E CG42306-RA ortho RpS3 CG42306-RA ortho CG42306-RA Ufd1-like ortho Ugt CG42306-RA ortho CG42306-RA Ergic53, isoform A, Ergic53, isoform B, LD43551p, Rhea ortho Flo-1 CG42306-RA ortho CG42306-RA CG8258, LD24495p ortho CG42306-RA Der-1 ortho CG42306-RA RuvB-like helicase 2 ortho CG42306-RA Coatomer subunit alpha ortho CG42306-RA Npl4 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q7K0S5 Q9W3F1 - 14605208 - X 2 Q7K0S5 Q9VJQ4 - 14605208 - X 2 Q8IH18 Q7K0S5 - 14605208 - X 2 Q7K0S5 A4V304 - 14605208 - X 2 Q7K0S5 Q9W3F1 two hybrid 14605208 direct interaction X 2 Q7K0S5 Q9VJQ4 two hybrid 14605208 direct interaction X 2 Q7K0S5 two hybrid 14605208 direct interaction X 2 Q7K0S5 L0MLQ9 two hybrid 14605208 direct interaction X 2 Q7K0S5 Q7KN62-2 affinity chromatography technology 22036573 physical association X 2 Q7K0S5 anti tag coimmunoprecipitation 25369031 - C 3 Q7K0S5 anti tag coimmunoprecipitation 25369031 - C 3 Q7K0S5 Q7KN62 anti tag coimmunoprecipitation 25369031 physical association X 2 Q7K0S5 Q7KN62 anti tag coimmunoprecipitation 25369031 physical association X 2 Q7K0S5 Q7KN62 anti tag coimmunoprecipitation 25369031 physical association X 2 Q7K0S5 Q7KN62 anti tag coimmunoprecipitation 25369031 physical association X 2 Q7K0S5 Q7KN62 MI:0809,(-) 25369031 physical association X 2 Q7K0S5 Q9W3F1 two hybrid 14605208 physical association X 2 Q7K0S5 Q9VJQ4 two hybrid 14605208 physical association X 2 Q8IH18 Q7K0S5 two hybrid 14605208 physical association X 2 Q7K0S5 Q7K3Z3 anti tag coimmunoprecipitation 25369031 physical association X 2 Q7K0S5 Q7K3Z3 anti tag coimmunoprecipitation 25369031 physical association X 2 Q7K0S5 P09087 two hybrid 14605208 physical association X 2 Q7K0S5 anti tag coimmunoprecipitation 25294943 association C 13 Q7K0S5 Q9W3F1 two hybrid 14605208 physical association X 2 Q7K0S5 Q9VJQ4 two hybrid 14605208 physical association X 2 Q7K0S5 anti tag coimmunoprecipitation 25294943 association C 24 Q8IH18 Q7K0S5 two hybrid 14605208 physical association X 2 Q7K0S5 P09087 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Gint3 TER94 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_71970 bait prey Gint3 CG12116 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0465(dip) BIOGRID_37499|UniProt_64702|DIP_10682 prey|prey|- bait|bait|- Gint3 l(2)35Bd MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|MI:0465(dip) UniProt_49766|BIOGRID_33100|DIP_22565 prey|prey|- bait|bait|- Gint3 CG32016 MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(biogrid) DIP_21321|BIOGRID_44453 -|prey -|bait Abd-B Gint3 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|(intact) BIOGRID_37025|DIP_9845|UniProt_63904 bait|-|null prey|-|prey Gint3 CG11097 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_27039 prey bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9XZ56 Q7K0S5 THOR GINT3 0.126 25294943 Q7K0S5 P09087 GINT3 ABD-B 0.21 14605208 Q8IH18 Q7K0S5 4E-T GINT3 0.183 14605208 Q9VJQ4 Q7K0S5 L(2)35BD GINT3 0.183 14605208 Q9W3F1 Q7K0S5 Q9W3F1 GINT3 0.183 14605208 Q99323 Q7K0S5 ZIP GINT3 0.126 25294943 Q9VVX3 Q7K0S5 FZ2 GINT3 0.126 25294943 Q7K0S5 Q24372 GINT3 LAC 0.126 25294943