iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074631

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02064418

Gene Name

KLHL21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000003743.3	ENSOCUT00000003742.3	ENSOCUP00000003243.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-19	69.9	36	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.00e-10	38.1	136	164

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    Dvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           Dv+l+ + g+ f+ah++vLaa+S++F+a+f ++l+es+  ++v +++v p+ ++ ll+F+Ytg++ 
   Q: 36   DVTLEAAgGRDFPAHRAVLAAASPYFRAMFAGQLRESR-AERVRLHGVPPDMLQLLLDFSYTGRVA 100
           9*****99******************************.************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkh 30
            Ncl++ +fA++++c+ L++aa++fil+h
   Q: 136  ANCLDMQDFAEAFSCSGLASAAQRFILRH 164
           6***************************9 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MERPAPLAVL PFSDPAHALS LLRGLSQLRA ERKFLDVTLE AAGGRDFPAH RAVLAAASPY 60
FRAMFAGQLR ESRAERVRLH GVPPDMLQLL LDFSYTGRVA VSGDNAEPLL RAADLLQFPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCGGC CGGCGCCCCT GGCCGTGCTG CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 60
CTGCTGCGCG GCCTGAGCCA GCTCCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035853--P:chromosome passenger complex localization to spindle midzone
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	86.32	0.00e+00	856.00
IUUC-Apl-003189	Anas platyrhynchos	85.28	2.00e-141	494.00
IUUC-Ani-009467	Aspergillus nidulans	35.29	7.00e-08	51.20
IUUC-Ame-011774	Astyanax mexicanus	55.46	1.00e-102	366.00
IUUC-Bta-012367	Bos taurus	87.71	0.00e+00	1012.00
IUUC-Cja-019501	Callithrix jacchus	80.10	0.00e+00	887.00
IUUC-Cfa-020550	Canis familiaris	87.38	0.00e+00	1004.00
IUUC-Cpo-022072	Cavia porcellus	86.71	0.00e+00	979.00
IUUC-Csa-023364	Chlorocebus sabaeus	86.46	0.00e+00	858.00
IUUC-Cin-025253	Ciona intestinalis	40.62	2.00e-123	435.00
IUUC-Csv-025871	Ciona savignyi	41.56	7.00e-128	451.00
IUUC-Dre-028694	Danio rerio	66.37	0.00e+00	754.00
IUUC-Dno-029082	Dasypus novemcinctus	82.63	0.00e+00	802.00
IUUC-Dor-030680	Dipodomys ordii	87.04	0.00e+00	1003.00
IUUC-Ete-032315	Echinops telfairi	83.56	0.00e+00	814.00
IUUC-Eca-033570	Equus caballus	94.22	0.00e+00	669.00
IUUC-Eeu-035067	Erinaceus europaeus	94.53	4.00e-147	514.00
IUUC-Fca-035663	Felis catus	93.19	1.00e-129	455.00
IUUC-Fal-037103	Ficedula albicollis	74.56	0.00e+00	777.00
IUUC-Gmo-039420	Gadus morhua	64.26	0.00e+00	723.00
IUUC-Gga-040161	Gallus gallus	72.40	0.00e+00	748.00
IUUC-Gac-041755	Gasterosteus aculeatus	65.79	0.00e+00	745.00
IUUC-Ggo-044899	Gorilla gorilla	87.38	0.00e+00	980.00
IUUC-Hsa-045834	Homo sapiens	88.01	0.00e+00	978.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	87.38	0.00e+00	1007.00
IUUC-Lch-050338	Latimeria chalumnae	64.71	0.00e+00	757.00
IUUC-Loc-051780	Lepisosteus oculatus	68.12	0.00e+00	764.00
IUUC-Laf-053725	Loxodonta africana	81.90	0.00e+00	882.00
IUUC-Mcc-055032	Macaca mulatta	86.93	0.00e+00	824.00
IUUC-Meu-056661	Macropus eugenii	78.83	7.00e-177	612.00
IUUC-Mpo-057626	Magnaporthe poae	31.67	4.00e-07	49.30
IUUC-Mga-059821	Meleagris gallopavo	80.69	4.00e-126	443.00
IUUC-Mdo-062095	Monodelphis domestica	82.75	0.00e+00	802.00
IUUC-Mmu-063138	Mus musculus	87.21	0.00e+00	1000.00
IUUC-Mpu-066386	Mustela putorius furo	96.57	0.00e+00	649.00
IUUC-Mlu-067807	Myotis lucifugus	91.29	0.00e+00	660.00
IUUC-Nle-069181	Nomascus leucogenys	87.02	0.00e+00	992.00
IUUC-Opr-070658	Ochotona princeps	87.71	0.00e+00	1036.00
IUUC-Ont-072209	Oreochromis niloticus	65.14	0.00e+00	734.00
IUUC-Oan-072861	Ornithorhynchus anatinus	90.23	3.00e-118	417.00
IUUC-Ola-087553	Oryzias latipes	64.26	0.00e+00	728.00
IUUC-Oga-088782	Otolemur garnettii	87.04	0.00e+00	999.00
IUUC-Oar-089634	Ovis aries	87.38	0.00e+00	1006.00
IUUC-Ptr-091259	Pan troglodytes	83.37	0.00e+00	685.00
IUUC-Pan-091734	Papio anubis	87.71	0.00e+00	984.00
IUUC-Psi-092979	Pelodiscus sinensis	73.91	0.00e+00	805.00
IUUC-Pma-094459	Petromyzon marinus	52.61	3.00e-76	279.00
IUUC-Pfo-097446	Poecilia formosa	65.32	0.00e+00	735.00
IUUC-Pab-098765	Pongo abelii	87.54	0.00e+00	1003.00
IUUC-Pca-101018	Procavia capensis	99.42	2.00e-94	339.00
IUUC-Pva-102730	Pteropus vampyrus	84.05	0.00e+00	955.00
IUUC-Rno-104972	Rattus norvegicus	86.54	0.00e+00	996.00
IUUC-Ssc-115869	Sus scrofa	86.22	0.00e+00	826.00
IUUC-Tgu-116562	Taeniopygia guttata	74.34	0.00e+00	795.00
IUUC-Tru-118490	Takifugu rubripes	64.61	0.00e+00	731.00
IUUC-Tni-119898	Tetraodon nigroviridis	62.68	0.00e+00	694.00
IUUC-Ttr-128976	Tursiops truncatus	96.48	2.00e-150	525.00
IUUC-Xtr-132876	Xenopus tropicalis	68.82	0.00e+00	795.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence